Population Aging Intensifies, Lub Phenomenon ntawm Senile Dementia yuav tshwm sim, Yuav ua li cas tiv thaiv nws?

Raws li United Nations tsis ntev los no tau tshaj tawm World Population Prospects 2022 tsab ntawv ceeb toom, cov pej xeem thoob ntiaj teb tau mus txog 8 billion hnub no, thiab tus lej no tseem yuav loj hlob ntxiv rau ntau xyoo tom ntej, tab sis kev loj hlob yuav tsum qeeb.Cov pej xeem thoob ntiaj teb xav tias yuav nce mus txog 8.5 billion los ntawm 2030, 9.7 billion los ntawm 2050, nce siab txog li 10.4 billion hauv 2080s, thiab txuas ntxiv mus txog 2100, tsab ntawv ceeb toom tau hais.Tsis tas li ntawd, nce lub neej expectancy, ua ke nrog poob fertility tus nqi, yuav exacerbate ntiaj teb no pejxeem laus.

Dab tsi yuav cuam tshuam rau cov neeg laus dua?Raws li qhov xwm txheej tam sim no muaj kev txhawj xeeb, tus nqi fertility tsawg txhais tau tias qee cov neeg laus yuav ntsib teeb meem nyiaj laus yav tom ntej. Txawm hais tias cov neeg no tuaj yeem thov rau cov kev cai cuam tshuam ntawm lub xeev thiab tau txais qee qhov txiaj ntsig zoo, lawv tseem tsis tuaj yeem nyob kaj siab lug thaum lawv laus vim yog lub cev tsis zoo.

Tshwj xeeb, senile dementia, maj mam poob nco thiab ua lub nra rau lwm tus, yog ib yam uas cov neeg laus feem ntau txais tsis tau.Feem ntau senile dementias suav nrog Alzheimer's kab mob thiab vascular dementia.

Cov tsos mob dab tsi ua rau senile dementia muaj? ‍

1. Kev ua haujlwm thaum ntxov

Nyob rau theem pib ntawm Alzheimer's disease, cov neeg mob yuav muaj kev nco tsis tu ncua, xws li txoj kev lawv feem ntau taug kev, dheev ploj mus ib hnub, lossis tej yam uas lawv yuav tsum ua, tsis tau ua tiav ob peb zaug, thiab qee cov neeg mob yuav muaj cov tsos mob. phenomenon ntawm nco dislocation, confuse ib yam nrog rau lwm tus.

2. Kev ua haujlwm nruab nrab

Alzheimer's tus kab mob nyob rau hauv nruab nrab theem, tsis nco qab qhov kev ua tau zoo tej yam yuav loj heev, tsuas yog tshwm sim feem ntau tsis nco qab, txawm tsis nco qab lub npe ntawm tsev neeg, thiab cov phooj ywg, thiab tsis paub qhov txawv ntawm cov txiv neej thiab cov poj niam.Thaum cov neeg laus nkag mus rau theem mob no, lawv tsis tuaj yeem saib xyuas lawv tus kheej thiab feem ntau xav tau cov neeg hauv tsev neeg lossis cov neeg saib xyuas tshwj xeeb los saib xyuas lawv.

3. Kev ua haujlwm lig

Nyob rau hauv nruab nrab thiab lig theem ntawm Alzheimer's tus kab mob, cov neeg laus yuav nkag mus rau tag nrho tsis tuaj yeem saib xyuas lawv tus kheej, txawm tias lawv cov lus ua haujlwm thiab kev muaj peev xwm txav mus los yuav maj mam poob, txhua yam ntawm kev muaj peev xwm degrade tiag tiag, ua rau cov neeg laus tsuas tuaj yeem ua tau. mus pw tsaug zog.

Koj yuav tsum ua dab tsi hauv koj lub neej kom tsis txhob muaj kab mob Alzheimer? ‍

1. Cov khoom noj khoom haus muaj nyob rau hauv qhov chaw

Txhawm rau kom noj qab haus huv thiab tswj lub hlwb ua haujlwm, nws tseem ceeb heev uas yuav tsum tau ua tib zoo saib xyuas cov khoom noj khoom haus thiab kev sib koom ua ke.Cov neeg laus mob siab rau kev noj zaub mov ntau, xws li noj cov zaub mov muaj protein ntau, cov khoom noj muaj fiber ntau, tsim nyog kom txo tau cov rog, kub, thiab ntsev, tib lub sijhawm yuav tsum tau xyuam xim kom tsis txhob nqus tau qee yam teeb meem. , xws li haus luam yeeb lossis cawv, thiaj li khaws tau body ib puag ncig meej txaus, txhua yam ntawm kev ua haujlwm kuj tuaj yeem ua haujlwm ib txwm, suav nrog lub hlwb. Yog tias cov neeg laus noj zaub mov tsis zoo, ces lub nra ntawm txhua yam ntawm lub cev yuav nce ntxiv, lub hlwb muab ntshav thiab oxygen tsis txaus, thiab lub peev xwm cuam tshuam yuav ua rau tsis zoo.Ntawm lawv, muaj ntau yam khoom noj uas tiv thaiv Alzheimer's kab mob, xws li mis nyuj, qe, nqaij thiab lwm yam khoom noj muaj protein ntau, thiabCistanche.

Yees duab: Faw Cistanche

Kev tshawb fawb qhia tias tag nrho glycosides ntawmCistanchetuaj yeem nce qib kev kawm thiab kev nco ntawm AD nas tshwm sim los ntawm quinolinic acid (QA), txo cov ntsiab lus ntawm malondialdehyde (MDA) hauv cov ntaub so ntswg los ntawm quinolinic acid, thiab nce glutathione peroxidase (glutathione). peroxidase (GSH-Px), superoxide dismutase (superoxide dismutase, SOD) kev ua haujlwm, txo acetylcholine esterase (acetylcholine esterase, TChE) kev ua, lub hlwb apoptosis tus nqi, thiab txo cov calcium tsub zuj zuj hauv lub hlwb. Cov txheej txheem yuav cuam tshuam nrog kev txhim kho ntawm cov dawb radical scavenging enzyme kev ua, txo cov lipid peroxidation, txo cov calcium hauv cov ntaub so ntswg, thiab inhibition ntawm QA-induced hlwb hlwb apoptosis; Thib ob, tag nrho glycosides ntawm cistanche tuaj yeem nce -AP thiab aluminium trichloride Qhov tshwm sim yog AD nas txoj kev kawm thiab kev nco, txo qis hauv hlwb cov ntaub so ntswg MDA cov ntsiab lus, nce SOD thiab GSH-Px kev ua, txhim kho qee yam kev hloov pauv hauv lub hlwb, thiab txo cov hlwb hlwb. apoptosis tus nqi. Nws cov txheej txheem ntawm kev ua haujlwm kuj tseem cuam tshuam nrog nws cov haujlwm antioxidant.

Duab: Cistanche Cov txiaj ntsig

Tag nrho glycosides ntawmCistanchekuj tseem tuaj yeem muaj kev tiv thaiv zoo ntawm ultrastructure ntawm hippocampus ntawm D-galactose qauv nas, thiab muaj kev sib raug zoo ntawm koob tshuaj. Nws tau kwv yees tias tag nrho glycosides ntawm cistanche tuaj yeem ncua kev laus thiab tiv thaiv Alzheimer's kab mob los ntawm kev siv tshuaj antioxidant. nyhuv.

Daim duab: Cov teebmeem ntawm Cistanche kho Alzheimer's disease

CistancheExtract tuaj yeem nce qib protein ntau ntawm nicotinic acetylcholine receptor (nAChR) 3 thiab 7 receptor subunits hauv SH-SY5Y hlwb, thiab tiv thaiv qib ntawm 3 thiab 7 receptor subunits tshwm sim los ntawm A 25-35 Kev txo qis ntawm A tuaj yeem txo qhov cell puas thiab nce lipid peroxidation theem tshwm sim los ntawm A; Nws tseem tuaj yeem txhawb nqa axon kev loj hlob ntawm nas pheochromocytoma (PC12) hlwb thiab nce rat glioma (Gioomas, C6) hlwb Cov theem ntawm cov paj hlwb loj hlob (NGF), nrog rau nas hippocampal axon kev loj hlob, neuron sib txawv, thiab synapse tsim, thiab tuaj yeem txhawb nqa qhov tso tawm ntawm NGF hauv nas cortex thiab hippocampus, txhim kho kev kawm thiab kev nco muaj peev xwm ntawm nas. Cov teebmeem no qhia tau tias cov tshuaj suav tshuajCistanchedeserticola extract muaj peev xwm los ua ib qho tshuaj rau kev kho mob ntawm AD.

Nyem qhov no kom paub ntau ntxiv txog Cistanche

2. Kev sib raug zoo

Qhov tseeb, tsis yog cov tub ntxhais hluas xwb, tab sis cov neeg laus kuj xav tau kev sib raug zoo, tsis muaj dab tsi thiab cov phooj ywg ua ke ua si mahjong, chess, seev cev square zoo heev, tsis tsuas yog tuaj yeem ua phooj ywg tab sis kuj tuaj yeem siv lub cev, txhim kho lub hlwb, noj qab nyob zoo.

Nrog cov phooj ywg, nws yooj yim dua rau cov neeg laus nrhiav cov ncauj lus thiab nyiam nyiam. Yog tias qhov lawv nyiam ua raws li, cov neeg laus lub hlwb yuav tsum tau ua haujlwm tas li kom tsis txhob muaj teeb meem ntawm kev puas siab puas ntsws.

3. Ua kom muaj kev ua ub ua no uas txhawb koj lub hlwb

Tib neeg lub hlwb hloov tau yooj yim dua, txawm tias mus rau hauv cov laus, thiab yuav ua raws li txoj cai no, yog tias cov neeg laus tsis muaj lub hlwb ua haujlwm hauv lub neej, ces qhov muaj peev xwm ntawm lub hlwb yuav pom qhov kev poob qis, thiab qhov tshwm sim ntawm dementia yuav nce ntxiv rau yav tom ntej. .

Yog li ntawd, nws tau hais tias cov neeg laus yuav tsum muaj kev tawm dag zog lub hlwb ntau dua hauv lawv lub neej, xws li tsim tus cwj pwm ntawm kev tawm dag zog, ua si qee qhov kev sib tw, lossis nrog rau cov tub ntxhais hluas nyob ib puag ncig lawv thiab tau txais qee qhov "cov ntsiab lus paub". Tsuas yog thaum lub hlwb tau tsim kho tas li, lub peev xwm ntawm txhua yam ntawm lub hlwb puas tuaj yeem tswj hwm qhov qub?

4. Kho koj tus cwj pwm

Qee cov neeg laus yuav ntshai heev txog Alzheimer's kab mob. Piv txwv li, muaj ib hnub, lawv mam li nco dheev ib yam thiab xav tias lawv muaj dementia. Cov kev xav zoo li no tsis pom zoo.Kev xav txog tus kheej mus ntev yuav cuam tshuam rau lub hlwb ntawm cov neeg laus, kev puas siab puas ntsws tsis raug yuav cuam tshuam rau lub siab, qhov kev xav ntau dua, qhov kev xav tsis zoo ntawm lub hlwb, tab sis tsis haum rau kev noj qab haus huv.Nws tau hais tias peb muab tus cwj pwm ncaj nraim hauv lub neej, thiab ua tib zoo saib xyuas, kom nws muaj txiaj ntsig zoo rau kev noj qab haus huv.

Yog li ntawd, Alzheimer's disease tuaj yeem tiv thaiv tau, tsuav yog cov ntsiab lus saum toj no, tuaj yeem txo qhov kev pheej hmoo ntawm kev raug mob los ntawm tus kab mob no.