Muaj kwv yees li 10 lab tus neeg mob Alzheimer's nyob hauv Suav teb. Cov kev tsis nkag siab no yuav tsum tau nkag siab

Tsis nco qab cov txheeb ze nyob ib ncig ntawm koj, tawm mus thiab nrhiav tsis tau koj txoj hauv kev, thiab txawm hloov koj lub siab nyiam... Hauv Suav teb, muaj txog 10 lab tus neeg laus uas raug mob zoo li no. Txhua lub Cuaj Hlis 21st yog World Alzheimer's Day, tseem hu ua "World Alzheimer's Day". Koj paub ntau npaum li cas txog tus kab mob no?

Txhua 3 vib nas this, muaj tus neeg mob Alzheimer's nyob hauv lub ntiaj teb

Alzheimer's disease feem ntau hu ua Alzheimer's disease. Vim muaj kev qias neeg coj los ntawm lub npe, ntau tus neeg mob thiab lawv tsev neeg tsis kam mus nrhiav kev kho mob thiab tsis kam tham txog Alzheimer's disease. Txawm li cas los xij, "Lub Ntiaj Teb Alzheimer's Disease 2018 Report" tso tawm los ntawm Alzheimer's Disease International (ADI) qhia tias txhua 3 vib nas this, muaj tus neeg mob dementia hauv ntiaj teb. Muaj tsawg kawg yog 50 lab tus neeg mob dementia thoob ntiaj teb. Los ntawm 2050, tus lej ntawd yuav tsum ncav cuag 152 lab. Ntawm lawv, kwv yees li 60-70 feem pua ​​​​yog cov neeg mob Alzheimer. Hauv Suav teb, pab pawg no kuj loj heev. Tam sim no muaj txog 10 lab Alzheimer's cov neeg mob hauv Suav teb, thiab nws xav tias los ntawm 2050, yuav muaj ntau dua 40 lab tus neeg mob Alzheimer hauv Suav teb, ntau dua li cov pej xeem ntawm Canada.

Nyem Cistanches herba thiab citrus bioflavonoids rau Anti Alzheimer's kab mob

Alzheimer's yog ib yam kab mob

Alzheimer's disease yog dab tsi?

Qhov tseeb, Alzheimer's disease yog ib qho kev paub tsis meej uas tshwm sim los ntawm lub hlwb raug mob lossis kab mob, thiab qhov loj ntawm qhov kev poob qis no ntau dua li qhov kev loj hlob ntawm kev laus ib txwm muaj. Senile kev paub tsis meej, feem ntau hu ua "dementia", muaj ntau yam kev faib tawm, suav nrog Alzheimer's kab mob, frontotemporal dementia, vascular dementia, Lewy lub cev dementia, kab mob prion, thiab lwm yam. Ntawm lawv, Alzheimer's kab mob suav rau qhov tseem ceeb. Kev paub txog kev poob qis los ntawm cov lus hais saum toj no yog dementias irreversible. Ntau tus neeg ntseeg tias cov tsos mob xws li kev nco tsis zoo nyob rau theem pib ntawm Alzheimer's disease yog qhov tshwm sim ntawm kev laus thiab tsis tas yuav mus ntsib kws kho mob. Tab sis qhov tseeb, nyob rau hauv lub xyoo caum ntawm Alzheimer's kab mob kev loj hlob, kev txawj ntse dysfunction, txav tsis meej pem, kev muaj peev xwm ua neej nyob txhua hnub, thiab txawm tuag tshwm sim ib tom qab. Kev kuaj mob ntxov thiab kev kho mob ntxov yog qhov tseem ceeb heev. "Qee tus neeg xav tias 'kev tsis meej pem qub' yog qhov tshwm sim ntawm ntuj tsim. Qhov no yog kev nkag siab yuam kev. Kev nco poob tau muab faib ua physiological thiab pathological, thiab tom kawg xav tau kev saib xyuas." Sun Yongan, tus kws kho mob tus thawj coj ntawm Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv ntawm Peking University Thawj Tsev Kho Mob. Sun Yongan tau hais ntxiv tias yog tias ib yam dab tsi tsis nco qab tuaj yeem rov qab tau tom qab tau ceeb toom, thiab nws tuaj yeem raug cais raws li lub cev kev nco qab, tab sis yog tias nws tsis tuaj yeem rov qab tau tom qab rov nco qab, nws yog qhov yuav tsum tau ceev faj txog kev nco qab.

Dab tsi yog cov tsos mob ntawm Alzheimer's disease kom paub txog?

Yog li, dab tsi yog cov tsos mob tshwj xeeb ntawm Alzheimer's disease? Zhang Nan, tus kws tshaj lij ntawm neurology ntawm General Tsev Kho Mob ntawm Tianjin Medical University, tau sau tseg raws li hauv qab no:

• Kev nco hloov uas cuam tshuam rau lub neej txhua hnub

• Yooj yim npaj tej yam los yog daws teeb meem

• Nyuaj ua haujlwm paub hauv tsev, tom haujlwm, lossis thaum ua si lom zem

• Tsis meej pem txog lub sijhawm lossis qhov chaw

• Nyuaj to taub cov duab pom thiab kev sib raug zoo spatial

• Cov teeb meem tshiab nrog kev siv cov lus hauv kev hais lus lossis kev sau ntawv

• Cov khoom yog misplaced thiab poob lub peev xwm los saib rov qab thiab rov ua dua

• Deterioration los yog tsis muaj zog ntawm kev txiav txim

• Tawm haujlwm lossis ua haujlwm hauv zej zog

• Kev hloov ntawm lub siab thiab tus cwj pwm

Cov kws kho mob hais tias thaum cov tsos mob saum toj no tshwm sim, yuav tsum tau them nyiaj mloog, thiab yog tias lawv tshwm sim ntau zaus, lawv yuav tsum mus rau hauv tsev kho mob kom kuaj xyuas lub sijhawm.

Dab tsi yog qhov muaj feem cuam tshuam rau Alzheimer's disease?

Dab tsi yog qhov muaj feem cuam tshuam rau Alzheimer's disease? Feem ntau, cov kws kho mob muab faib ua ob pawg: yam uas tswj tsis tau thiab tswj tau. Ntawm lawv, cov yam ntxwv uas tswj tsis tau muaj xws li hnub nyoog, noob caj noob ces, keeb kwm ntawm tsev neeg, thiab lwm yam. "Qhov kev nthuav dav nce ntxiv nrog lub hnub nyoog, qhov tshwm sim ntawm cov neeg muaj hnub nyoog tshaj 65 xyoo yog ntau dua 3 feem pua, thiab nws yog siab dua thoob ntiaj teb. Feem ntau, nws yog hais txog. 3 feem pua ​​​​rau 7 feem pua ​​. Ntau tshaj 85 xyoo Yog, txog 50 feem pua ​​.” Zhang Nan hais. Tsis tas li ntawd, cov yam ntxwv tswj tau muaj xws li ntshav qab zib mellitus, midlife hypertension, midlife rog, txo kev ua lub cev, kev nyuaj siab, kev haus luam yeeb, thiab kev kawm qis. Tab sis cov no yog tiv thaiv tau.

Puas yog Alzheimer's disease kho tau?

"Alzheimer's kab mob yog tiv thaiv tau tiag tiag. Los ntawm kev tiv thaiv kev kub ntxhov, plab rog, hnov ​​​​lus tsis zoo, ntshav qab zib, thiab lwm yam kab mob, thiab noj ntau dua aerobic ce thiab lwm yam kev ntsuas, qhov tshwm sim ntawm dementia tuaj yeem txo los ntawm 1/3." Sun Yongan tau hais tias vim muaj coob tus neeg tsis paub, thiab tsis to taub, ncua sijhawm rau kev kuaj mob ntxov thiab kho ntxov. Hais txog kev kho mob, kev kho mob ntawm Alzheimer's tus kab mob suav nrog kev kho tshuaj thiab kev kho tsis yog tshuaj. Ntawm lawv, kev kho tshuaj muaj xws li cholinesterase inhibitors, NMDA receptor antagonists, thiab lwm yam, thiab cov kev kho mob uas tsis yog tshuaj muaj xws li kev txawj ntse, kev tawm dag zog aerobic, kho lub teeb, kho hluav taws xob / sib nqus, thiab lwm yam. "Tam sim no cov tshuaj tsis tuaj yeem kho tus kab mob Alzheimer's, tab sis kev noj tshuaj tuaj yeem pab ncua kev loj hlob ntawm tus kab mob thiab txhim kho lub neej zoo ntawm cov neeg mob. Qhov kev kuaj mob ua ntej thiab kev kho mob, qhov txiaj ntsig zoo dua." Sun Yongan hais.

Cov neeg mob Alzheimer xav tau kev saib xyuas thiab nkag siab ntau dua

Raws li xyoo 2018, Tuam Tshoj cov neeg laus hnub nyoog tshaj 60 xyoo suav txog 17.9 feem pua ​​​​ntawm cov pej xeem hauv lub tebchaws, thiab yav tom ntej, cov pej xeem hnub nyoog 65 xyoos thiab tshaj saud yuav dhau los ua pawg hnub nyoog loj tshaj plaws. Txawm li cas los xij, lub hnub nyoog ntawm 65 xyoo kuj yog lub sijhawm siab tshaj plaws rau Alzheimer's disease. Cov neeg laus loj hlob sai sai thiab lub nra hnyav yog cov teeb meem ceev uas lub neej tam sim no yuav tsum tau ntsib. Txawm li cas los xij, hauv Suav teb, Alzheimer's disease tseem ntsib qhov "peb lows" - kev paub tsawg, tus nqi kho mob qis, thiab qis dua ntawm kev txais kev kho mob. Cov neeg mob Alzheimer's feem ntau tsis nco qab, tsis quav ntsej, thiab tsis to taub los ntawm tib neeg. Tsis tas li ntawd, vim muaj kev cuam tshuam ntawm lub tswv yim ntawm "filial piety", tam sim no, Tuam Tshoj tseem muaj kev tswj hwm los ntawm tsev neeg cov nyiaj laus. Daim ntawv tshaj tawm ntawm International Alzheimer's Disease Association" tau taw qhia tias tsev neeg cov qauv nyiaj laus rau qee yam zais qhov mob Alzheimer's mob hnyav hauv Suav teb, thaum cov neeg saib xyuas tsev neeg nkees ntawm 24- teev tsis tu ncua, thiab lub cev. thiab kev puas siab puas ntsws nyob rau hauv lub sij hawm loj heev, muaj kev tsis txaus ntawm cov kev pab cuam ntawm kev sib raug zoo, thiab cov kev xav tau ntawm cov qauv thiab cov qauv kev kuaj mob thiab kev kho mob thiab kev saib xyuas tib neeg thiab kev kho kom rov zoo yog nyob deb ntawm kev ua tiav. Qee tus neeg hais tias tsis muaj dab tsi txaus ntshai tshaj li kev tuag ntau dua li kev tsis nco qab los ntawm cov neeg hlub. Txawm hais tias cov cuab yeej siv kho mob uas twb muaj lawm tsis tuaj yeem kho tus kab mob no, nws yuav yog qhov tseem ceeb dua rau cov neeg mob Alzheimer's thiab lawv tsev neeg kom muaj kev nkag siab ntau dua ntawm tus kab mob thiab muab kev nkag siab thiab kev txhawb nqa rau lawv.

Cov tshuaj ntsuab zoo tshaj plaws rau Alzheimer's disease

Cistanche tshuaj ntsuabtuaj yeem nce qib protein ntau ntawm nicotinic acetylcholine receptor (nAChR) 3 thiab 7 receptor subunits hauv SH-SY5Y hlwb, thiab tiv thaiv qib ntawm 3 thiab 7 receptor subunits tshwm sim los ntawm A 25-35. Kev txo qis ntawm A tuaj yeem txo cov cell puas thiab nce qib lipid peroxidation los ntawm A; Nws kuj tseem tuaj yeem txhawb nqa axon kev loj hlob ntawm pheochromocytoma (PC12) hlwb hauv cov neeg mob Alzheimer's kab mob, thiab nce lub hlwb ntawm cov neeg mob Alzheimer's disease. Qib ntawm cov paj hlwb loj hlob (NGF) hauv glioma (Gioomas, C6) hlwb, nrog rau kev loj hlob ntawm hippocampal axon,neuronalkev sib txawv, thiab synapse tsim nyob rau hauv hippocampus ntawm cov neeg mob nrogAlzheimer tus kab mobkab mob, tuaj yeem txhawb nqa Alzheimer's Kev tso tawm ntawm NGF hauv cerebral cortex thiab hippocampus ntawm cov neeg mob Alzheimer's kab mob ua kom zoo dua qub.kev kawmthiabnco.

Yog xav paub ntxiv: Ali.ma@wecistanche.com