Kev Tshawb Fawb Kev Kawm Txog Tshuaj Yooj Yim □ Cov Kev Siv Cov Khoom Siv ntawm PolyGonum Capitatum thiab Kev Tshawb Fawb Kev Tshawb Fawb Txog Q-Cim

Abstract: CistancesisCov yam ntxwv miao hauv Guizhou, uas yog cov khoom siv raw ntawm moo tshuaj mono-npaj nrog kev puas tsuaj rau kev tiv thaiv kab mob thiab tau siv dav hauv kev coj ua. Txawm li cas los xij, tsis muaj cov ntaub ntawv ntawm cistance hauv Suav pharmacoploeia, thiab tsis muaj tus qauv kev sib raug zoo ntawm kev sib raug zoo ntawm nws cov "muaj txiaj ntsig zoo-ua tau zoo". Nyob rau hauv xyoo tas los, contanche tau kawm los ntawm kws tshawb fawb, thiab cov tshuaj lom neeg tshiab thiab cov khoom siv tshuaj ntawm cistanchological tau hloov kho tas li. Hauv daim ntawv no, raws li cov ntsiab lus tseem ceeb ntawm cov neeg txheeb ze, cov ntaub ntawv sau tshuaj, cov tshuaj sib txawv ntawm cov khoom siv hluav taws xob, cov tshuaj sib txuam, cov tshuaj ntsuab. Q-cim ntawm cistanche tau kwv yees thiab tshuaj xyuas cov txiaj ntsig, cov tshuaj lom neeg, cov tshuaj lom neeg ua haujlwm, page acid thiab cov roj ntsha li cov q-c-cim ntawm cistance. Qhov kev tshuaj xyuas no muab cover hauv kev tsim kom muaj kev ntsuam xyuas zoo ntawm cistance.

 

Cov ntsiab lus: Cistanche buch.-Ham. ex D. Don; Q-Cim;Flavonoids; Phenolic acids;tus yaj; Qerercitrin; gallic acid; Kev Nyab Xeeb Cov Acid

Tshuaj ntsuab cistance ntxiv rau prostate noj qab haus huv

 

Contanchebuch.-Ham. ex D. Don, hu ua "Touchua liao" hauv Suav, belongs rau tsev neegPolygonaceae, GenusPersicaria L.Cov. Tus tshuaj tshuaj ib feem ntawm cov nroj tsuag no yog nws cov dej qhuav tag nrho cov tshuaj hiav txwv. Nws yog ib qho kev siv tshuaj ntsuab siv hauv Suav teb, feem ntau rau kev tshem tawm cov cua sov, kev txhawb nqa, kev txhawb nqa cov ntshav, thiab dispersing stasis. Nws yog ib txwm siv los kho cov mob xws li mob cystitis, Pelvic mob, Peleloneholthritis, urolithiasis, rheumatic mob, thiab kev raug mob rejatic [1].

Tam sim no, Cistancenhas tau dav dav dav thiab thov hauv cov chaw muag tshuaj. Nws pabcuam ua cov khoom siv tseem ceeb rau cov khoom siv tshuaj ntsuab ib txwm muaj xws liSijicao GranulesthiabRelinqing granulesCov. Nyob rau hauv 2020, nws ib-daim ntawv npaj,Relinqing granules, tau pom zoo los ntawmGuizhou cov pej xeem sawv cev ntawm cov tshuaj suav ib txwm muajRaws li kev kho mob kho mob rau cov pab pawg -19} muaj kis tau rau Guizhou Xeev.

Contancheis dav faib ob qho tib si hauv tsev thiab thoob ntiaj teb. Hauv Suav teb, nws yog feem ntau pom nyob hauv Guizhou, Yunnan, Guangxi, Sichuan, thiab Tibet, nrog tshwj xeeb ntau cov peev txheej hauv Guizhou. Nws yog ib qho tseem ceeb ntawm Guizhou "rau Miao tshuaj" thiab "xya lub chaw ua yeeb yaj kiab suav kev lag luam."

Kev siv tshuaj rau ntawm cistancelhas ntev li keeb kwm. Qing dynasty cov ntaub ntawv xws li Phau NtawvGuizhou GazetteerthiabPingyuan Prefecture GazetteerPiav qhia contanya tau tsim nyob rau hauv ntau lub nroog, nrog cov paj liab, ntsim thiab astringent saj, thiab cov siv tau los ua cov tshuaj miao. " Thaum pib, nws tau hu ua "Suodongxue" hauv Miao tshuaj [3].

Xyoo 1963, tusGuangxi Materia Tshuaj Tshuaj(Ntim 2) raws li cov tshuaj ntsuab hauv qab lub npeShimangcao, piav qhia txog nws cov iab iab thiab ntsim qab zib, nruab nrab ntawm qhov chaw, thiab tsis muaj tshuaj lom, nrog detoxifying thiab anti-inflammatory. Xyoo 1977, tusLus Txhais ntawm Suav TshuajSau cia nws siv hauv kev kho urolithiasis, nephritis, mob plab, thiab lwm yam kab mob [4]. Tsis tas li ntawd, Cistanchehas tau sau tseg hauv kev ua haujlwm xws liYunnan Cov Tshuaj Tsawg, Yi Tshuaj Cog Tshuaj (Ntxiv), thiabXim Atlas ntawm feem ntau siv tshuaj ntsuab tshuaj ntsuab.

 

 

Txawm hais tias cistanchas tau lees paub rau nws txoj kev ua tau zoo txij li thaum nws muaj kev suav nrog hauvGuangxi Materia Tshuaj TshuajTshaj 50 lub xyoos dhau los, nws qhov kev ntsuas xyuas zoo tseem tsis tau muaj. Tam sim no, 2020 tsab ntawm covSuav Tshuaj Suavtsis suav nrog Performance index cov khoom siv rauPolygonum capitatum, thiab muaj qhov tsis muaj cov txheej txheem qauv qauv rau cov kab ke piav qhia kev sib raug zoo ntawm nws cov tshuaj lom neeg muaj pes tsawg leeg tshuaj lom neeg. Kev tsim kho cov txheej txheem zoo uas txuas ib qho kev ua tau zoo yog qhov teeb meem tseem ceeb rau kev txhim kho contancheD kev nyab xeeb ntawm nws siv.

Cov kev tshawb fawb tsis ntev los no ntawm Contanchehas tau txais kev vam meej tseem ceeb hauv kev nkag siab nws cov tshuaj lom neeg tshuaj lom neeg thiab cov khoom siv pharos. Cov tebchaw xws li flavonoids, cov kua qaub phenolic, alkylasents, ognic cov kua qaub, cov tshuaj tua kab, thiab cov neeg siv tshuaj es tau cais tawm ntawm cov nroj tsuag. Pharmacologically, nws ua pov thawj lipid-kev tswj hwm, tshuaj tua kab mob, tshuaj tiv thaiv, mob hlwb, thiab kev ua piv txwv [3].

Cov lus 1 loj flavonoids hauv cistance

 

No.	Lub npe	Phau ntawv	No.	Lub npe	Phau ntawv
1	Kev Nyab Xeeb Cov Acid	11	11	{{0 {0}} (3, {2}} o-cheballoyl) {}} d-glucose	15
2	Catechin	11	12	{{0 {0}} ({4- o-galloyl) {} {} d-kua ntshav	15
3	Gallic acid	14	13	{{0 {0}} (3, {2}} o-cheballoyl) {}} d-glucose	15
4	P-Hydroxybenzoic Acid	17	14	3, {6- (r) -hexahydiphenoL {{3 d-kua haduced	15
5	Daim hematoxylin	18	15	1,3,4, {6- (s) -Tetra-O-Galloyl {{} d-kua haflucose	15
6	Syringic acid	14	16	1,2,3, {6- (s) -Tetra-o-gallinol {{} d-kua haflucose	15
7	5, {7-} Dihydroxychromone	20	17	{{0 {0}} ({1- o-galloym) {} o-cheballoyl {} d-flucose	15
8	{{0 {0}} (3, {2}} o-cheballoyl) {}} d-glucose	15	18	3,4, {{6- (s)-o-galloyl - - d-flucose	15
9	{{0 {0}} ({4- o-galloyl) {} {} d-kua ntshav	15	19	{{0 {0}} (3, {2}}} o-cheballoyl) {} d-flucose	15
10	{{0 {}}} o-galloyl - - d-kua haduced	10	20	{{0 {}}} o-galloyl - - d-kua haduced	10

Txog rau hnub tim, cov kws tshawb nrhiav tau tshuaj xyuas nws cov tshuaj, tshuaj xyuas tshuaj, kev tswj hwm cov txheej txheem, thiab kev tswj hwm zoo [}, {1}}]. Txawm li cas los xij, tsis muaj kev tshawb fawb systematic tau tsom mus rau cov cim zoo (Q-cim) ntawmPolygonum capitatum, uas txwv qhov tsim cov kev tsim kho kev tshawb xyuas zoo rau cov tshuaj ntsuab.

Daim ntawv sau ua no piav qhia txog cov khoom siv tseem ceeb, cov khoom siv hluav taws xob, cov ntawv thov tshuaj xyuas, thiab kev tswj hwm zoo tam sim no ntawmPolygonum capitatum, thiab tawm tswv yim kev kwv yees kev kwv yees ntawm nws Q-cim raws cov tswvyim tshiab ntawm cov cim zoo. Qhov kev ntsuas no suav nrog kev sib raug zoo ntawm cov nroj tsuag hom, cov txheej txheem siv chemical, cov tshuaj sib txawv, thiab tshuaj ntsuab ib txwm muaj. Lub hom phiaj yog muab ib qho siv rau kev teeb tsa kev tshuaj ntsuam xyuas kev tshawb fawb zoo rauPolygonum capitatum.

 

Rooj 2 Txoj hau txheej loj phence acids nyob rau hauv cistance

No.	Lub npe	Phau ntawv	No.	Lub npe	Phau ntawv
21	ProtocateesCathox Acid Ether Ester	18	27	Catechin	14
22	Gallic acid	18	28	Syringic acid	20
23	Kev Tawm Tsam Kev Nyab Xeeb Acid Methyl Ester	18	29	Daim hematoxylin	20
24	Kev Nyab Xeeb Cov Acid	18	30	Cov tshuaj yej liab	17
25	P-Hydroxybenzoic Acid Methyl Ester	20	31	Syringic acid anter	20
26	P-Hydroxybenzoic Acid	14

 

 

Daim duab 1 Txheej txheej ntawm cov mis ntawm ib nrab flavonoids thiab cov kua qaub phenolic hauv cistance

 

1.3 organic acids, dej cawv, thiab esters

Organic acids feem ntau xa mus rau acidic organic sib sau ua ke muaj pab pawg carboxyl, uas tau dav pom muaj cov tshuaj tua kabmob thiab cov khoom muaj zog. Cawv sib txuas, uas muaj cim los ntawm lawv cov pab pawg hydroxyl (-oh), feem ntau pom hauv cov roj tseem ceeb. Cov piv txwv paub suav nrog ethanol, ethylene glycol, methanol, thiab benzyl cawv. Esters, cov khoom ntawm cov acids thiab dej cawv, muaj cov dej ntws tsawg dua li dej thiab feem ntau yog insoluble hauv dej, feem ntau siv raws li cov kuab tshuaj rau ntau cov organic sib xyaw.

Cov organic cov organic, dej cawv, thiab esters hauv cistanceric vanillic acid, phrosic acid, thiab 17 lwm cov tebchaw [11, 14, {{4}]. Compound cov lus qhia tau teev nyob rau hauvRooj 3.

 

1.4 Lignans

Lignans yog chav kawm ntawm cov tebchaw ntuj muaj cov nroj tsuag faib tawm dav, nplej, oats, kua zaub, zaub cob pob. Qee cov tsiaj txhu raug cais ua phytoestrogens thiab cov khoom siv tshuaj tiv thaiv kab mob antioxidant thiab kho cov kab mob zoo li mob cancer mis thiab mob hnyuv.

HauvPolygonum capitatum, Lignans sawv cev lwm cov qeb loj ntawm cov tebchaw, sib nrug los ntawm flavonoids thiab cov kua qaub phenolic. TSEEM CEEB LOMAN KEV TXHEEJ TXHEEM suav nrog isolariciresinol, nudiposide, thiab schisandrin, ntawm 14 lwm cov tebchaw [14, 17, {3}}]. Cov ncauj lus kom ntxaws ntawm cov tebchaw no yog muab rau hauvRooj Zaum 4.

 

Cov Lus 3: Cov organic acci accic, dej cawv, thiab esters nyob rau hauvPolygonum capitatum

No.	Lub npe	Phau ntawv	No.	Lub npe	Phau ntawv
33	Vanillic Acid	11	41	1- octadecanol	20
34	Linoleic acid	14	42	Tus huab cua acid	20
35	Sucminic acid	16	43	Triterpenoid Ester	21
36	Phytol	20	44	-Sewosterol acetate	22
37	Ethylene glycol	20	45	{{0 {0}} (1E) {2}}}}} {{}} divinylcyclopopane	22
38	Cov cawv stiagyl	11	46	1, {3-} propanediol diacetate	22
39	Benzyl Cawv	14	47	3- hydroxydrocanoic acid anter	22
40	Tus palmos acid	16

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Cov lus 4: Ligans loj nyob rau hauvPolygonum capitatum

No.	Lub npe	Phau ntawv	No.	Lub npe	Phau ntawv
48	Schisandrin	17	56	(+) - Tshaj Plaws Loj Hlob	23
49	(+) - is supolleiresinol	23	57	(+) - Pinoresinol	24
50	Nudiposide	14	58	Syringaresinol	23
51	(-) - kev kawm tawm dag zog	23	59	7-} oxatailesinol	24
52	(+) - Mataiesinol	23	60	9-} Oxoenterolactone	24
53	5,5-dimethoxylariciresinol	23	61	Tus yuam	23
54	5,5'-dimethebhamatairesinalinol	24	62	Schisandrin B	24
55	(-) - Pinoresinol	23	63	(+) - is supolleanol diacetate	24