Cov ntsiab lus ntawm Lub Sijhawm Ciaj sia ntawm Tus Kab Mob Coronavirus Tshiab Hauv Ib puag ncig

Thov hu rauoscar.xiao@wecistanche.comyog xav paub ntxiv

Droplet thiab kev sib cuag ntawm neo-coronavirus tau pom tias yog txoj hauv kev tseem ceeb ntawm kev sib kis, tab sis ntev npaum li cas tus kabmob tshiab tuaj yeem nyob hauv ib puag ncig? Nws yog lub ntsiab lus ntawm peb qhov kev txhawj xeeb, vim tias tus kab mob no muaj sia nyob ntev dua, qhov muaj feem cuam tshuam rau peb kis tau ntau dua.

Thaum Lub Ob Hlis 2020 cov kws tshaj lij los ntawm Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau hais tias nws muaj peev xwm ua rau tus kabmob muaj sia nyob hauv ib puag ncig ob peb hnub yog tias qhov kub thiab av noo yog qhov raug [1,2]. Cov nqe lus no tsis meej heev, yog li puas muaj cov kev tshawb fawb cuam tshuam hauv tsev thiab txawv teb chaws lossis tsis?

Kuv yuav coj koj los txheeb xyuas cov kev tshawb fawb tsis ntev los no ntsig txog tus mob coronavirus tshiab thiab kev zam rau ib puag ncig.

Thov nias ntawm no kom paub ntxiv

1. Qhov kev kam rau tus kab mob no yog dab tsi?

Thaum Lub Peb Hlis 10, lub chaw kho mob preprint platform medRxiv tau tshaj tawm txoj kev tshawb fawb txog kev muaj sia nyob ruaj khov ntawm cov kab mob coronaviruses tshiab hauv aerosols thiab ntawm qhov chaw sib txawv, hu ua "Aerosol thiab qhov chaw ruaj khov ntawm HCV-19 (SARS-CoV-2) piv to SARS-CoV-2. Kab lus no tau xa mus rau phau ntawv xov xwm kho mob uas muaj koob npe tshaj plaws, New England Journal of Medicine (NEJM), thiab cov ntawv tseem tsis tau raug tshuaj xyuas.

Daim duab saum toj no sawv cev rau kev sib piv ntawm qhov muaj peev xwm ntawm neo-CoV thiab SARS tus mob coronavirus tom qab fogging, nrog rau qhov kub thiab txias ntawm 21-23 degree thiab 65 feem pua ​​​​ntawm cov av noo. Nws tau pom tias tus kab mob muaj sia nyob tuaj yeem muaj sia nyob hauv aerosol tom qab fogging rau 3 teev, nrog rau ntau yam kev ua kis las zoo ib yam li tus kabmob SARS.

Cov kws tshawb fawb kuj tau ua qhov kev sim ntawm qhov chaw ntawm cov ntaub ntawv uas sawv cev ntawm ntau qhov chaw nyob thiab ua haujlwm, xws li yas (polypropylene), alloyed stainless hlau, tooj liab, thiab cardboard. Cov txiaj ntsig tau pom tias tus kabmob tshiab no tau ruaj khov tshaj plaws ntawm cov yas thiab cov hlau tsis muaj steel, muaj peev xwm ciaj sia mus txog 72 teev.

Plaub cov ntaub ntawv tshwj xeeb tau pom lub sijhawm muaj sia nyob ntawm tooj liab (3.4 teev) < duab los qhia (8.45 teev) < stainless hlau (13.1 teev) < yas (15.9 teev).

Nws yog ib qho tseem ceeb uas hais txog ib nrab-lub neej, ib nrab-lub neej ntawm tus kabmob tshiab no tau ntev dua li ntawm tus kabmob SARS ntawm cov khoom siv zoo li daim duab los qhia, nrog tus nqi nruab nrab ntawm 8.45 teev.

Cistanche tuaj yeem txhim kho kev tiv thaiv

2. Dab tsi yog qhov muaj sia nyob ntawm cov kab mob ntawm lwm qhov chaw?

Ntxiv nrog rau aerosol, yas, stainless hlau, cardboard, thiab tooj liab cov ntaub ntawv saum npoo, dab tsi yog qhov muaj peev xwm ntawm cov kab mob ntawm lwm cov khoom siv, xws li cov khoom siv textile?

"NHS lub vev xaib piav qhia tias lub sijhawm muaj sia nyob ntawm tus kab mob tom qab tawm hauv lub cev nyob ntawm qhov chaw ntawm cov khoom nws txuas nrog, nrog rau cov xwm txheej ib puag ncig xws li kub thiab av noo."

Zuag qhia tag nrho, cov kab mob muaj sia nyob ntev dua ntawm cov khoom tsis-permeable (waterproof) qhov chaw, xws li stainless hlau lossis yas; Cov kab mob muaj sia nyob rau lub sijhawm luv luv ntawm qhov chaw permeable xws li cov ntaub fibers lossis ntawv phuam.

Ib daim ntawv luam tawm xyoo 2014 hauv American Journal of Infection Control los ntawm cov kws tshawb fawb los ntawm ntau lub teb chaws, suav nrog Tebchaws Askiv, Fabkis, Tebchaws Meskas, thiab Tuam Tshoj, tau tshuaj xyuas lub sijhawm muaj sia nyob ntawm tus kab mob khaub thuas A (H1N1) ntawm plaub qhov chaw.

Cov kws tshawb fawb tau ua ntau qhov piv txwv thiab kev tshuaj xyuas ntawm cov ntoo, stainless hlau, yas, thiab ntaub nto hauv tsev.

Cov txiaj ntsig tau pom tias cov ntoo saum npoo yog qhov zoo tshaj plaws "ua liaj ua teb" rau tus kab mob no, thiab tus kab mob no tuaj yeem ua kom muaj peev xwm kis tau rau 48 teev; Lub sijhawm muaj sia nyob ntawm tus kab mob ntawm cov hlau tsis muaj steel thiab cov yas yas feem ntau yog li 24 teev; Lub sijhawm muaj sia nyob ntawm tus kab mob txuas rau ntawm daim ntaub yog qhov luv tshaj plaws, thiab cov haujlwm ntawm tus kab mob yuav sai sai poob mus rau xoom hauv 8 teev.

Lwm daim ntawv luam tawm xyoo 2016 hauv American Journal of Applied and Environmental Microbiology tau saib ntau ze ntawm kev ciaj sia ntawm cov kab mob khaub thuas H1N1 ntawm cov hlau tsis muaj hlau nyob hauv ib puag ncig sib txawv.

Txoj kev tshawb no qhia tias tus kab mob khaub thuas tuaj yeem muaj sia nyob ntawm cov hlau tsis muaj steel ntev txog 7 hnub thiab tseem muaj peev xwm kis tau. Txoj kev tshawb no qhia tau hais tias "lub sijhawm tos ntev heev" ntawm cov kab mob khaub thuas rau ntawm qhov chaw tsis muaj dej.

Ua ke nrog cov kev tshawb fawb ntsig txog, peb tuaj yeem xav tias tus kabmob tshiab no yuav tsum muaj cov yam ntxwv zoo sib xws, nyob rau hauv cov khoom siv permeable lub sijhawm muaj sia nyob tsawg dua li cov ntaub ntawv uas tsis yog permeable.

3. Dhau li ntawm kev sib cuag nrog cov ntaub ntawv saum npoo, dab tsi cuam tshuam nrog cov kab mob hauv ib puag ncig?

Otter et al. (2016) tau tshawb xyuas cov xwm txheej rau kev ciaj sia ntawm cov kab mob uas muaj peev xwm kis tau zoo xws li H1N1, H5N1, thiab H5N7 kab mob khaub thuas, thiab mob hnyav ua pa nyuaj (SARS) / Middle East respiratory syndrome (MERS) coronaviruses (CoV) ntawm cov chaw suav nrog cov kab mob sib kis. , titration, nto hom, ncua kev kawm ntawv nruab nrab, deposition hom, kub, thiab txheeb ze humidity,. thiab txoj kev ntsuas tus kab mob ciaj sia [4].

Peb kawm txog hom ntog hauv ntu dhau los, thiab peb mus rau qhov cuam tshuam ntawm qhov kub thiab txias, thiab kev hloov pauv ntawm tus kab mob.

Cistanche tuaj yeem txhim kho kev tiv thaiv

4. Qhov kub thiab av noo ntawm cov kab mob yog dab tsi?

VanDoremalen et al. (2013) txoj kev tshawb fawb tau txiav txim siab qhov ruaj khov ntawm Middle East Respiratory Syndrome coronavirus (MERS-CoV) ntawm 20 degree -40 feem pua ​​txheeb ze av noo (RH), 30 degree -30 feem pua ​​RH thiab 30 degree -80 feem pua ​​RH.

MERS-CoV tau ruaj khov dua nyob rau hauv qhov kub thiab qis qis thiab tseem zoo li qub tom qab 48 teev. Thaum lub sij hawm aerosolization ntawm MERS-CoV, tsis muaj qhov txo qis hauv kev ruaj ntseg ntawm 20 degree -40 feem pua ​​RH [5].

Duan et al. (2003) tau kawm txog cov thermal susceptibility ntawm tus kab mob SARS thiab pom tias tus kab mob no ruaj khov rau tsawg kawg yog 2 h ntawm 4 degree, 20 degree, thiab 37 degree tsis muaj kev hloov pauv tseem ceeb hauv kev kis kab mob hauv lub cev, tab sis tsis kis kab mob tom qab 90, 60. , thiab 30 min ntawm raug ntawm 56 degree, 67 degree, thiab 75 degree, feem [6].

Xyoo 2010, cov kws tshawb fawb ntawm Harvard Tsev Kawm Ntawv Kev Noj Qab Haus Huv tau pom tias cov kab mob tsis nyiam qhov kub thiab txias thiab cov av noo siab thiab lub caij ntuj sov yog qhov tsim nyog rau kev tswj tus kab mob.

Yog li cov txiaj ntsig ntawm MERS thiab SARS tus mob coronaviruses, peb tuaj yeem xav zoo sib xws tias qhov kub thiab qis qis yog qhov zoo rau kev muaj sia nyob ntawm tus kabmob tshiab, thiab qhov kub thiab txias thiab cov av noo tsis zoo rau kev ciaj sia ntawm tus kabmob tshiab.

5. Puas muaj kev hloov pauv ntawm tus kab mob uas yuav kis tau rau tib neeg yav tom ntej?

Tsis muaj cov ntaub ntawv hais txog kev tshawb fawb ntawm neo-coronavirus tau pom, thiab peb xa mus rau txoj kev tshawb fawb ntawm tus kab mob Ebola, tsis muaj qhov sib txawv ntawm kev ruaj ntseg ntawm tus kab mob hauv aerosol xyoo 1976 thiab 2014, ob qho tib si muaj sia nyob tau 180 feeb. Tam sim no, tsis muaj pov thawj tias tus mob coronavirus tshiab muaj peev xwm hloov pauv tau ntau.

6. Kev lag luam zaub mov yuav tsum paub txog dab tsi?

Ua ke nrog cov yam ntxwv saum toj no ntawm tus kabmob tshiab, peb hauv kev lag luam khoom noj yuav tsum tau saib xyuas lub sijhawm muaj sia nyob ntawm tus kabmob tshiab no hauv ib puag ncig thiab ua haujlwm zoo ntawm kev tiv thaiv thiab kev tswj hwm.

Kev tswj ntawm qhov chaw sib cuag ntawm cov neeg ua haujlwm siab.

1) Txheeb xyuas qhov twg yog peb qhov chaw sib tiv tauj ntau zaus, tshwj xeeb tshaj yog cov khoom siv tsis zoo ntawm cov khoom sib cuag xws li cov ntaub ntawv yas thiab stainless hlau, cov rooj sib tham, cov khoom siv ua haujlwm, cov ntsiav tshuaj, countertops, thiab lwm yam.

2) tshuaj tua kab mob ntawm qhov chaw tiv tauj tsis tu ncua, piv txwv li, siv 75 feem pua ​​​​ntawm cawv.

3) mob siab rau kev ntxuav tes, thiab pom zoo rau cov hnab looj tes rau txoj haujlwm uas muaj kev pheej hmoo siab, xws li cov neeg nyob hauv kev sib cuag nrog cov hlau tsis muaj steel, yas, thiab cov thawv ntawv.

4) Nco ntsoov qhov kev sib cuag tsis ncaj qha ntawm aerosols, ua qhov cua nquag, tshuaj tua kab mob rau qhov chaw kaw, tsis muaj kev sib sau ntawm cov neeg ua haujlwm, thiab lwm yam.

kev xav

Niaj hnub no, tib neeg sim uatxhim kho lawv kev tiv thaivlos ntawm kev noj qee yam zaub mov lossis tshuaj ntxiv. Thiab ntawm lawv muaj cov tshuaj ntxiv uas ua haujlwm zoo dua li lwm tus. cov lus teb yog Cistanche. nrog tsis muaj kev phiv. Nws ua haujlwm li casCistanche Polysaccharides thiab Verbascum glycosidesnyob rau hauv cistanche tuaj yeem nce qhovenzymeKev ua haujlwm ntawm lub plawv thiab lub hlwb cov ntaub so ntswg, thiab txhim kho phagocytic kev ua haujlwm ntawm lub plab zom mov, thiab lymphocyte proliferation, yog licistanchetuaj yeem txo qhov feem ntau ntawm kev kis tus kabmob Omicron.

Kab lus no yog kho los ntawm Wecistanche