Cistance tubulosa: cov tshuaj kawm science rau pob txha noj qab haus huv & osteoporosis tiv thaiv
Apr 15, 2025
Cistanche tubulosa: txhawb cov pob txha hauv plab los ntawm kev txawj ntse txawj ntse & kev tshawb fawb niaj hnub
Khw ua lag luam Snapshot:
✔ TSHIAB 200M + Osteoporosis Cov Neeg Mob Hauv Ntiaj Teb, nrog 3 tus poj niam tshaj 50 cuam tshuam
✔ ✔ 34% nce hauv pob txha ceev cov cim pom nrog cistance extracts (ovx nas)
✔ 60% ntawm nutraceutical cov neeg yuav lus nrhiav kev xaiv cov nroj tsuag rau bisphosphonates
✔ Khij vojrified 40-60% Echinacoside cov ntsiab lus muaj los ntawm cov Pony-ntawv pov thawj tus neeg muag khoom
Mechanism ntawm Kev Ua: Yuav ua li cas cistanche masters pob txha rov kho dua
Cov kev tshawb fawb soj ntsuam pom tau ua qauv cistanche's tripey-kev txiav txim mus kom ze los ntawm opp / rank pathway:
- OPG upregulation:Nce osteoprotrin Ntau Lawm los ntawm 2.1X hauv Osteooblasts (hauv Cov Khoom Siv Vitro)
- Dibll Kev:Txo cov receptor activator ntawm NF-κB Ligand qhia los ntawm 58%
- Estrogenic kev hloov kho:Khi rau er receptors nrog 73% affinity vs. 17 - esttradiol
-
Cistanche organic extract
Cov ntaub ntawv pov thawj kho mob: Los ntawm kev sim mus rau cov txiaj ntsig tiag tiag
| Kawm Qauv | Ntsiab lus tseem ceeb | Cistance Kev Cuam Tshuam |
|---|---|---|
| Ovx nas (6 lub hlis) | BMD, cuab tam -5 b, opp / rankl piv | ↑ 34% BMD ↓ 41% pob txha rov qab kho cov cim |
| Cov poj niam postmenopausal (n =120) | Lumbar txha nraub qaum | 5.2% nce vs placebo (12-} lub hlis mus sib hais) |
| Nyob rau hauv vitro osteoclasts | Qeb qhia |
79% inhibition ntawm sib txawv
|
Kev qhia-qib rau cov kws sau ntawv
Xav tau cov cim zoo los ntawm cov chaw muab khoom:
- Nquag teb:Ntau dua los yog sib npaug rau 75% phenylethanoid glycosides (HPLC-txheeb xyuas)
- Cov hlau hnyav:Tsawg dua los yog sib npaug rau 3ppm arsenic, tsawg dua los yog sib npaug rau 1ppm cadmium (ICP-MS Cov Ntawv Qhia)
- Kev Nyab Xeeb Microbial:Tag Nrho Cov Phaj Suav<10,000 CFU/g
- Sourcing:Wildralfted los ntawm Sab Hauv Tebchaws Mongolia Des suab puam Ecosystems
-
Cistanchoe Organic Bases Nyob Ze Nyob Ze Wecistanche Hoobkas
-
WhatsApp Peb rau cov lus qhia ntxiv
Cov ntawv thov kev xaiv ya rau hauv pob txha mob
Kev tsim kho txoj kev:
• Cov Neeg Saib Noj Ua Si: Ua ke nrog Calcium & Vitamin D3
• pab cov kis las: pawg nrog collagen peptides
• Cov Khoom Noj Khoom Haus: Enteric-Coated ntsiav tshuaj rau txhim kho kev nqus
• Cov tshuaj tsw qab: transdermal xa mus rau hauv zej zog kev txhawb nqa
Cov av nplaum hauv av: kev ntseeg Suav cov tuam ntxhab
- Xinjiang Suab puam Botanicals:Tshwj xeeb hauv CO2 supercritical rho tawm (40% Yuam Kev)
- Gansu Herbal hav:Muaj cov organic-ntawv pov thawj raw khoom (EU / NOP qauv)
- Ningxia TCM rho tawm:Muab cov kev cai sib piv (10: 1 txog 50: 1 concentrates)
Cov ntawv txheeb xyuas cov neeg siv khoom rau cov neeg yuav khoom thawj zaug
- Thov COA nrog HPLC / LC-MS Kev Pom Zoo ntawm Cov Cai
- Paub meej tias CFDA ntawv pov thawj xwm txheej
- Soj ntsuam cov txheej txheem (dej / ethanol nyiam)
- Sib tham moqs (Txuj Ci: 25kg nruas; qauv: 500g)
-
Tawm tswv yim kev tshawb fawb pem hauv ntej
Txiav-Edd Trudies qhia txog cov txiaj ntsig ntxiv:
- Synergistic muaj txiaj ntsig nrog genistein (kua isoflavones)
- Kev sib cais ntawm cov plab hnyuv liab axis ntawm cov kev sib txuas lus microbiome
- Kev tiv thaiv ntawm glucocorticicoid-induced pob txha poob
Kev Cai Tswj:Contanche feem ntau pom tau tias muaj kev nyab xeeb (Gras) hauv Asmeskas thiab tau kev pom zoo hauv EU cov kev cai tshiab cov cai noj mov (2015/2283). Yuav tsum sab laj cov kws ua raws cai rau cov tub phiaj kev ua lag luam.
