Suav Cov Kws Tshaj Lij Pom Kev Pom Zoo Ntawm Kev cem quav ntev Ⅱ

2. Etiology thiab pathophysiology

5. Lub etiology ntawm kev cem quav ntev muaj xws li kev ua haujlwm, cov organic, thiab cov tshuaj tiv thaiv.

Kev cem quav ntev tuaj yeem muab faib ntxiv rau hauv plab hnyuv loj (tseem hu ua idiopathic cem quav lossis cem quav) thiab cem quav thib ob raws li etiology. Kev cem quav los ntawm cov kab mob ua haujlwm feem ntau yog tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm cov leeg nqaij leeg hauv txoj hnyuv, qhov quav, thiab qhov quav, nrog rau kev cem quav, kev ua haujlwm tsis zoo, thiab cem quav-predominant irritable bowel syndrome (IBS-C), thiab lwm yam. muaj feem xyuam rau ntau yam, feem ntau yog cov kab mob organic thiab cov laj thawj ntsig txog tshuaj. Cov kab mob hauv nruab nrog uas ua rau cem quav feem ntau suav nrog cov kab mob metabolic, kab mob neurogenic, kab mob hauv plab hnyuv loj (xws li mob qog noj ntshav), thiab lwm yam. Cov tshuaj tiv thaiv cem quav feem ntau yog tshwm sim los ntawm cov tshuaj anticholinergic, opioids, calcium antagonists, antidepressants, antihistamines, antispasmodics, thiab anticonvulsants. Hauv kev kho mob cem quav, qhov ua rau cov kab mob organic lossis cov tshuaj muaj feem cuam tshuam yuav tsum tau daws ua ntej, yog li nws tseem ceeb heev uas yuav tsum tau ua tib zoo nug cov keeb kwm kev kho mob thiab ua cov kev ntsuam xyuas cuam tshuam los txiav txim cem quav uas cuam tshuam txog cov organic thiab tshuaj.

Nyem rau laxatives rau cem quav

6. Raws li kev hloov pauv pathophysiological, cem quav uas tshwm sim los ntawm cov kab mob ua haujlwm tuaj yeem muab faib ua ntu ntu ntu ntu (NTC), cem quav qeeb qeeb (STC), cem quav, thiab cem quav.

Cov txheej txheem defecation tib neeg feem ntau yog nyob ntawm kev sib koom ua ke ntawm plab hnyuv motility, secretion, visceral sensation, pelvic pem teb cov leeg, thiab enteric paj hlwb. Lub cev colonic motility yog yam ntxwv los ntawm segmental thiab propulsive peristaltic contraction kev ua. Cov txheej txheem ntawm cov quav propulsion mus rau lub qhov quav thiab qhov quav feem ntau yog nyob ntawm qhov ua tiav propulsive peristaltic contraction ntawm cov nyuv generated los ntawm kev sib koom tes ntawm colonic myenteric plexus, plab hnyuv Cajal hlwb, thiab plab hnyuv neurotransmitters. Kev tshem tawm cov quav hauv qhov quav thiab qhov quav feem ntau yog nyob ntawm kev sib koom ua ke ntawm cov leeg hauv plab thiab sab hauv thiab sab nraud qhov quav sphincters.

Kev ua haujlwm tsis zoo ntawm cem quav tshwm sim nyob rau hauv kev sib koom ua ke ntawm ntau yam pathophysiological mechanisms, nrog rau txoj hnyuv motility, plab hnyuv secretion disorder, hloov nyob rau hauv visceral rhiab heev, pelvic pem teb nqaij dysfunction, thiab enteric nervous system dysfunction. Raws li cov txiaj ntsig ntawm lub sijhawm hloov pauv hauv lub cev, kev ua haujlwm ntawm lub cev, thiab kev defecography, kev ua haujlwm cem quav tuaj yeem muab faib ntxiv rau NTC, STC, cem quav, thiab cem quav.

NTC yog hom kab mob ntau dua ntawm kev ua haujlwm cem quav. Cov neeg mob uas muaj cov kev kuaj colonic transit function tests muaj cov tsos mob ntawm cem quav. Los ntawm ntau yam kev kuaj mob ntawm lub sij hawm colonic transit, nws pom tau tias muaj kev ncua ncua sij hawm nyob rau hauv tag nrho cov nyuv los yog txhua ntu ntawm cov nyuv nyob rau hauv cov neeg mob nrog STC, uas yog tshwm sim los ntawm tsis txaus colonic propulsion, txo colonic motility, thiab txo colonic propulsive. Kev ua haujlwm peristaltic contraction, ua rau lub sijhawm ntev ntawm cov quav los ntawm txoj hnyuv. Nws yog tus cwj pwm los ntawm cov tsos mob hnyav xws li defecation tsis tu ncua, mob plab zom mov, thiab cov quav qhuav, tab sis tsis muaj kev sib koom ua ke defecation. Defecation disorder constipation feem ntau yog hais txog paradoxical contraction thiab insufficiency ntawm so ntawm lub pelvic pem teb cov leeg nqaij los yog qhov nce ntawm lub qhov quav nyob rau hauv lub siab thaum tus neeg mob sim mus defecate, uas ua rau muaj kev cuam tshuam cov quav excretion. Cov neeg mob uas muaj kev cem quav tsis zoo feem ntau muaj ntau yam kev hloov pauv pathophysiological, piv txwv li, ntau tshaj li ib nrab ntawm cov neeg mob uas quav quav quav quav cawv kuj muaj lub sij hawm ntev ntawm txoj hnyuv. Ntau tshaj 2/3 ntawm cov neeg mob STC muaj kev tsis sib haum xeeb ntawm kev sib koom tes. Los ntawm kev ntsuas siab, nws tau pom tias 40% ntawm NTC, 47% ntawm STC, 53% ntawm kev quav dej quav cawv, thiab 42% ntawm cov neeg mob cem quav tau yoo mov lossis postprandial colonic nro thiab kev ua raws li txo qis. Cov kev tshawb fawb tseem pom tau tias 43% ntawm cov neeg mob STC tau yoo mov colonic motility thiab ib txwm teb rau noj mov thiab bisacodyl stimulation ntawm colonic motility.

Ntuj Herbal Tshuaj Rau Relieving cem quav-Cistanche

Cistanche yog ib tug genus ntawm parasitic nroj tsuag uas belongs rau tsev neeg Orobanchaceae. Cov nroj tsuag no paub txog lawv cov khoom siv tshuaj thiab tau siv hauv Cov Tshuaj Suav Tshuaj (TCM) rau ntau pua xyoo. Cov hom Cistanche feem ntau pom muaj nyob hauv thaj av qhuav thiab suab puam ntawm Tuam Tshoj, Mongolia, thiab lwm qhov chaw ntawm Central Asia. Cistanche nroj tsuag yog tus cwj pwm los ntawm lawv cov nqaij tawv, yellowish stems thiab muaj nuj nqis heev rau lawv cov txiaj ntsig kev noj qab haus huv. Hauv TCM, Cistanche ntseeg tau tias muaj cov khoom siv tonic thiab feem ntau yog siv los kho lub raum, txhim kho qhov tseem ceeb, thiab txhawb kev ua haujlwm ntawm kev sib deev. Nws kuj yog siv los daws cov teeb meem ntsig txog kev laus, qaug zog, thiab kev noj qab haus huv tag nrho. Thaum Cistanche muaj keeb kwm ntev ntawm kev siv tshuaj ib txwm siv, kev tshawb fawb tshawb fawb txog nws txoj kev ua tau zoo thiab kev nyab xeeb tsis tu ncua thiab txwv. Txawm li cas los xij, nws paub tias muaj ntau yam bioactive tebchaw xws li phenylethanoid glycosides, iridoids, lignans, thiab polysaccharides, uas tuaj yeem ua rau nws cov teebmeem tshuaj.

Wecistanche covcistanche hmoov, cistanche ntsiav tshuaj, cistanche capsules, thiab lwm yam khoom tsim los sivsuab puam cistancheraws li cov khoom siv raw, txhua yam muaj txiaj ntsig zoo rau kev tshem tawm cem quav. Cov txheej txheem tshwj xeeb yog raws li hauv qab no: Cistanche ntseeg tau tias muaj cov txiaj ntsig zoo rau kev tshem tawm cem quav raws li nws cov kev siv ib txwm siv thiab qee cov tshuaj uas nws muaj. Txawm hais tias kev tshawb fawb tshawb fawb tshwj xeeb ntawm Cistanche qhov cuam tshuam rau cem quav yog txwv, nws tau xav tias muaj ntau lub tswv yim uas yuav ua rau nws muaj peev xwm txo tau cem quav. Laxative nyhuv:Cistanchetau ntev tau siv nyob rau hauv tsoos suav tshuaj raws li ib tug tshuaj rau cem quav. Nws ntseeg tau tias muaj cov nyhuv laxative me me, uas tuaj yeem pab txhawb kev zom zaub mov thiab ua rau cem quav. Cov nyhuv no tuaj yeem raug ntaus nqi rau ntau lub tebchaw nyob hauv Cistanche, xws li phenylethanoid glycosides thiab polysaccharides. Moistening cov hnyuv: Raws li kev siv ib txwm siv, Cistanche suav hais tias muaj cov khoom siv moisturizing, tshwj xeeb yog tsom rau cov hnyuv. Txhawb nqa dej thiab lubrication ntawm cov hnyuv yuav pab tau cov cuab yeej soften thiab yooj yim dua, yog li no relieving cem quav. Anti-inflammatory Effect: cem quav tej zaum yuav txuam nrog o nyob rau hauv lub plab zom mov. Cistanche muaj qee qhov sib txuas, suav nrog phenylethanoid glycosides thiab lignans, uas ntseeg tau tias muaj cov tshuaj tiv thaiv kab mob. Los ntawm kev txo cov kab mob hauv cov hnyuv, nws tuaj yeem pab txhim kho kev zom zaub mov tsis tu ncua thiab txo qhov cem quav.