Tshuaj Chemical Cheebtsam ntawm Cistanche Deserticola rau kev txhim kho kev txawj ntse muaj nuj nqi

Kev paub yog hais txog cov txheej txheem uas lub paj hlwb tau txais cov lus qhia thiab ua rau lawv cov tswv yim, yog li tau txais kev paub. Kev paub txog kev txawj ntse muaj ntau yam kev txawj ntse, suav nrog kev nco, kev suav, kev taw qhia spatiotemporal, kev muaj peev xwm ua haujlwm, kev ua haujlwm, kev nkag siab lus thiab kev qhia, thiab kev siv. Cognitive dysfunction yog ib tug degenerative kab mob ntawm lub hauv paus paj hlwb, feem ntau tshwm sim raws li kev puas hlwb, dyscalculia, visuospatial impairment, executive dysfunction, apraxia, aphasia, agnosia, dementia, thiab lwm yam. Alzheimer's disease, vascular kev paub tsis meej, Lewy lub cev dementia, Xaiv kab mob, thiab lwm yam. [1]. Kev paub tsis meej yog tshwm sim nyob rau hauv cov neeg laus thiab nyob rau hauv qeb ntawm "dementia" hauv cov tshuaj suav tshuaj. Lub ntsiab ua rau thiab pathogenesis ntawm tus kab mob no yog deficiency ntawm lub raum essence thiab deficiency ntawm medullary hiav txwv. Cov tshuaj suav tshuaj suav hais tias lub raum khaws cov ntsiab lus thiab cov ntsiab lus tsim cov pob txha. "Tag nrho cov pob txha yog nyob rau hauv lub hlwb"... Deficiency ntawm lub raum essence, depletion ntawm lub medullary hiav txwv, poob ntawm nourishment nyob rau hauv lub hlwb, depletion ntawm medullary chaw thiab lub hlwb, thiab poob ntawm Vajtswv mechanism ua rau kev txawj ntse los yog txawm dementia. Yog li ntawd, tonifying raum essence yog ib txoj kev kho mob tseem ceeb rau kev paub tsis meej hauv cov tshuaj suav tshuaj.

Suab puam nyob cistanche-Anti Alzheimer's kab mob

Nyem qhov no mus saib Cistanche Txhim Kho Kev Nco thiab Tiv Thaiv Alzheimer's Disease cov khoom

【Nug ntxiv】 Email: cindy.xue@wecistanche.com / Whats App: 0086 18599088692 / Wechat: 18599088692

Cistanche deserticola, hu ua "desert ginseng", muaj cov teebmeem ntawm tonifying lub raum thiab nourishing ntshav essence. Qhov tshwm sim ntawm Cistanche deserticola nyob rau hauv ntau yam dynasties ' puzzle qauv tsuas yog thib ob rau ginseng [2]. Cistanche, feem ntau hu ua Da Yun, Jing Zhu, Zong Rong, Rou Song Rong, Di Jing, thiab Cun Yun, feem ntau yog faib rau hauv thaj chaw qhuav xws li suab puam thiab suab puam, muaj txog 22 hom thoob ntiaj teb. Cov nroj tsuag ntawm genus Cistanche hauv Suav teb yog ib txwm nyob rau sab qaum teb sab hnub poob xws li Inner Mongolia, Gansu, thiab Qinghai, feem ntau suav nrog suab puam Cistanche, tubular Cistanche, saline Cistanche, thiab xuab zeb Cistanche.

Suab puam ginseng

Raws li thaum ntxov raws li "Shennong Materia Medica Classic", nws tau hais tias cov khoom no "nourishes tsib lub cev, ntxiv dag zog rau yin, thiab muaj txiaj ntsig zoo thiab qi." Nyob rau hauv cov ntaub ntawv muaj feem xyuam, nws tau taw qhia tias Cistanche deserticola "yog cov tshuaj rau lub raum meridian thiab cov ntshav faib, uas yog siv los ntxiv qhov tsis muaj zog ntawm lub zog tseem ceeb. Ni Zhumo ntawm Ming Dynasty tau sau rau hauv nws "Compendium of Materia Medica": "Cistanche deserticola yog ib yam tshuaj uas txhawb nqa lub qhov rooj tseem ceeb, txhawb nqa lub raum qi, thiab txhawb nqa cov ntsiab lus thiab cov ntshav... Nws yog cov tshuaj uas muaj zog thiab noj qab haus huv uas sov tab sis tsis kub, nourishing tab sis tsis khov, sov tab sis tsis qhuav, thiab du tab sis tsis xau, li no lub npe ntawm calmness. " Cov khoom no tuaj yeem txhawb nqa cov ntsiab lus thiab cov ntshav los ntawm kev nkag mus rau lub raum, muaj txiaj ntsig zoo rau cov hluav taws hauv dej, txhawb nqa lub raum, ntxiv cov ntsiab lus ntxiv, thiab txhawb nqa cov pob txha thiab lub hlwb, yog li ua tiav lub hom phiaj ntawm kev txhim kho kev txawj ntse.

cistanche-tiv thaiv Alzheimer's kab mob

Chen Jing et al. [4] txheeb xyuas Cistanche deserticola raws li kev siv tshuaj hauv network thiab pom tias Cistanche deserticola tuaj yeem txhim kho cov neeg mob kev paub txog kev ua haujlwm. Zhang Kaimei [5] txheeb xyuas qhov kev sib raug zoo ntawm cov hom phiaj cov proteins raws li txoj hauv kev tsom xam, thiab cov txiaj ntsig tau pom tias Cistanche deserticola muaj cov teebmeem neuroprotective, feem ntau los ntawm kev tswj cov hom phiaj xws li CTNNBI, PTGS2, HMOXI, thiab cov kev taw qhia xws li Wnt, thiab P13K. -AKT, yog li txhim kho kev txawj ntse. Jia Jianxin et al. [6] pom tias Cistanche deserticola tuaj yeem txhim kho kev kawm thiab kev nco txog kev laus ntawm cov nas dementia sai (SAMP8). Wang Qing [7] random faib 124 tus neeg mob dementia ua ob pawg. Pab pawg kho mob tau kho nrog Cistanche deserticola tag nrho glycosides capsules, thiab pab pawg tswj tau kho nrog Anlishen. Cov txiaj ntsig tau pom tias qhov xwm txheej ntawm dementia hauv pab pawg kho mob tau zoo dua qub, thiab cov kev mob tshwm sim tau qis dua li cov hauv pawg tswj hwm. Hauv cov ntsiab lus, Cistanche deserticola thiab nws cov extracts tuaj yeem txhim kho kev paub tsis zoo thiab siv los kho cov kab mob xws li Alzheimer's kab mob thiab vascular dementia [8]. Cov kab lus feem ntau qhia txog cov tshuaj lom neeg thiab cov txheej txheem ntawm kev ua ntawm Cistanche deserticola hauv kev txhim kho kev txawj ntse thiab muab lub hauv paus rau kev tshawb fawb rau nws daim ntawv thov kho mob.

1 Chemical Constituents ntawm Cistanche deserticola

Cistanche deserticola muaj cov tshuaj lom neeg nplua nuj. Tam sim no, ntau tshaj 100 lub tebchaw tau raug cais tawm los ntawm cov kws tshawb fawb hauv tsev thiab txawv teb chaws, suav nrog phenyl ethanol glycosides, suab thaj, iridoids thiab lawv cov glycosides, lignans thiab lawv glycosides, amino acids, sterols, alkaloids, thiab lwm yam. [9-10] . Ntawm lawv, phenyl ethanol glycosides thiab suab thaj muaj kev txhim kho ntawm kev txawj ntse.

1.1 Phenylethanol glycosides

Phenylethanol glycosides yog lub ntsiab active Cheebtsam ntawm succulent stems ntawm lub genus Cistanche, thiab Suav Pharmacopoeia kuj taw qhia tias phenylethanoid glycosides yog ib qho tseem ceeb Cheebtsam rau kev txheeb xyuas thiab txiav txim cov ntsiab lus ntawm "Cistanche". Liu Wenjing et al. [11] rho tawm 12 phenylethanoid glycosides los ntawm Cistanche deserticola los ntawm cov kev tshawb fawb txog kev sim, xws li pas dej, Cistanche deserticola glycoside C, Saline Cistanche deserticola glycoside D, thiab Echinacetin. Thawj phenylethanoid glycoside compound kaw nyob rau hauv cov ntaub ntawv yog echinacea. Zhang Kaimei [12] cais heterologous glycosides los ntawm Cistanche deserticola, suav nrog chymosin B thiab chymosin B. Tu Pengfei li al. [13] taw qhia tias phenylethanoid glycosides muaj cov nyhuv tonifying lub raum thiab ntxiv dag zog rau yang. Ntawm cov phenylethanoid glycosides, echinacoside, poolside, thiab ergosterol glycosides muaj antioxidants thiab txhim kho kev kawm thiab kev nco muaj peev xwm [14]. Tsis tas li ntawd, kev tshawb fawb [15] pom tias phenylethanoid glycosides tuaj yeem ua rau muaj kev tiv thaiv neuroprotective, tiv thaiv kab mob, thiab lwm yam teebmeem.

Cov tshuaj tseem ceeb ntawm Cistanche deserticola

1.2 Carbohydrates thiab lawv cov Derivatives

Tom qab kev sib cais thiab kev ua kom huv, cov monosaccharides feem ntau yog tsim los ntawm qabzib, fructose, mannitol, glucuronic acid, galactose uronic acid, thiab lwm yam. Cov monosaccharides tsim ib txoj saw ncaj los yog ceg saw hlau polysaccharides los ntawm glycosidic bonds. Kev tshawb fawb [16-20] qhia tau hais tias D-mannitol thiab Cistanche deserticola polysaccharide (CDPS) tuaj yeem ncua kev laus ntawm daim tawv nqaij, txhim kho kev tiv thaiv kab mob, ua kom superoxide dismutase, thiab txo cov lipids hauv lub cev. Cai Kerui et al. [21] pom tias Cistanche deserticola polysaccharide tuaj yeem txo cov apoptosis ntawm paj hlwb, tiv thaiv lub hlwb paj hlwb ntawm cov nas laus uas raug ntxias los ntawm D galactose, thiab txhim kho kev tiv thaiv ntawm lub cev [15].

2 Lub tshuab ntawm Cistanche deserticola txhim kho kev txawj ntse

Kev tshawb fawb tau pom tias Cistanche deserticola tsis tsuas yog muaj lub luag haujlwm xws li kev tiv thaiv daim siab, tshuaj tiv thaiv kab mob, hluav taws xob tiv thaiv, hypoglycemic, tiv thaiv kev ua xua, thiab tiv thaiv kab mob qog noj ntshav, tab sis kuj muaj antioxidant, tiv thaiv kab mob, tiv thaiv kab mob, thiab cov teebmeem neuroprotective, yog li no txhim kho kev paub tsis meej [18,22-27].

Cov teebmeem ntawm Cistanche-Anti Alzheimer's disease

2.1 Clearing - Amyloid protein ntau

Cov kev hloov pauv hauv AD histopathology yog － Neuroinflammatory plaques tsim los ntawm kev tso tawm ntawm amyloid protein nyob rau sab nraum paj hlwb, yog li A Yog tias qhov kev tshem tawm muaj peev xwm txo qis, nws yuav ua rau A Deposition, yog li cuam tshuam rau kev txawj ntse. Roland et al Kev tshawb fawb ntawm AD qauv nas pom tau tias tag nrho glycosides ntawm Cistanche deserticola tuaj yeem txhim kho A Clearing peev xwm thiab txhawb kev rov qab los ntawm cov paj hlwb puas hauv cov qauv nas, yog li txhim kho kev txawj ntse. Tao Yichun et al. [29] pom tias Cistanche deserticola tuaj yeem cuam tshuam kev sim AD nas － Tso tawm ntawm amyloid qe dawb me ntsis, tshem tawm A, Nws muaj txiaj ntsig zoo rau kev rov ua haujlwm ntawm cholinergic neurons, yog li txhim kho kev txawj ntse.

2.2 Antioxidant thiab dawb radical scavenging

Qhov tshwm sim thiab kev loj hlob ntawm kev txawj ntse muaj feem cuam tshuam nrog oxidative kev nyuaj siab, uas yog ib qho ntawm cov teeb meem tseem ceeb uas ua rau muaj kev puas siab puas ntsws. Wang Lu et al. [25] pom tias tag nrho glycosides ntawm Cistanche deserticola tuaj yeem ua rau muaj kev ua ub no ntawm glutathione peroxidase thiab serum superoxide dismutase, ntawm qhov tsis sib xws, txo cov kev ua ntawm malondialdehyde, txhim kho lub peev xwm ntawm lub cev kom tshem tawm cov dawb radicals, tshem tawm cov peroxide ntau dhau hauv lub cev. lub cev, thiab txhim kho kev txawj ntse. Huang Huilian et al. [30] taw qhia tias tag nrho glycosides ntawm Cistanche deserticola tuaj yeem txhim kho kev kawm muaj peev xwm ntawm Alzheimer tus kab mob qauv nas, feem ntau yog los ntawm kev txhim kho cov haujlwm ntawm cov dawb radical scavenging enzymes, txo lipid peroxidation cov tshuaj tiv thaiv, inhibiting quinolinic acid-induced hlwb cell apoptosis, txo lub hlwb. cov ntaub so ntswg calcium cov ntsiab lus, yog li txhim kho kev kawm thiab kev nco muaj peev xwm, thiab txhim kho kev txawj ntse. Cai Kerui et al. [21] faib cov nas dementia rau hauv pawg tswj sib txawv thiab pawg saib xyuas. Los ntawm kev tshawb fawb, nws tau pom tias cov kev ua haujlwm ntawm serum superoxide dismutase thiab glutathione peroxidase kev ua haujlwm hauv pawg cistanche polysaccharide tau txhim kho, thiab tib lub sijhawm, DNA puas ntawm cov paj hlwb raug kho rau qee yam, thiab kev paub txog kev ua haujlwm tau zoo dua. Cistanche deserticola muaj cov nplooj zoo li glycosides uas tuaj yeem tiv thaiv amyloid protein A 25-35 induced SH-SY5Y cell puas yog tsuas yog ua tiav los ntawm antioxidant lossis kev tswj hwm txoj hauv kev ntawm cytochrome C, Bcl-2, thiab caspase-3 cell apoptosis, yog li txhim kho kev txawj ntse hauv cov neeg mob AD [31]. Echinosin ua lub luag haujlwm hauv kev tawm tsam cov amyloid deposition nyob rau hauv hippocampus ntawm nas tshwm sim los ntawm D-neneneba galactose, yog li pab tshem tawm oxygen-dawb radicals, txo cell deformation thiab poob los ntawm oxygen-dawb radical puas, thiab txhim kho kev kawm thiab nco lub peev xwm. AD nas [32].

2.3 Anti-inflammatory thiab immunomodulatory teebmeem

Lwm qhov laj thawj tseem ceeb rau kev puas siab puas ntsws yog kev ua kom microglia thiab tso tawm ntau ntawm cov kab mob inflammatory thiab kev tiv thaiv kab mob ntxiv rau cov protein. Echinoside exerts inhibitory nyhuv ntawm inflammatory teb thiab txhim kho kev txawj ntse muaj nuj nqi los ntawm kev txo cov tiam ntawm reactive oxygen hom (ROS) nyob rau hauv PC12 hlwb [26]. Tag nrho cov glycosides ntawm Cistanche deserticola tuaj yeem txhim kho lub peev xwm hloov pauv lymphocyte thiab phagocytosis ntawm peritoneal macrophages hauv cov nas laus uas raug ntxias los ntawm D-neneneba galactose. Nyob rau tib lub sijhawm, nws tuaj yeem ua kom cov haujlwm ntawm NK hlwb, cov ntsiab lus ntawm CD4+T hlwb thiab CD8+T hlwb, thiab cov ntsiab lus ntawm IL-2 hauv cov ntshav peripheral, yog li ua si lub luag haujlwm immunomodulatory thiab txhim kho kev kawm thiab kev nco muaj peev xwm [33]. Zhang Yuhe et al. [34] pom tias ob qho tib si qis molecular qab zib thiab polysaccharide los ntawm Cistanche deserticola tuaj yeem txhim kho phagocytic kev ua haujlwm ntawm RAW264 7 hlwb, uas muaj txiaj ntsig zoo rau kev tso tawm NO los ntawm RAW2647 hlwb. Txawm li cas los xij, tsuas yog qis molecular qab zib los ntawm Cistanche deserticola tuaj yeem txhim kho IKK ／ Ｉ κ Ｂ ／ ＮＦ － κ Ua kom lub B signaling txoj kev muaj txiaj ntsig zoo rau IL-6 thiab TNF - Kev qhia ntawm cov proteins ua kom lub cev tsis muaj zog phagocytic kev ua haujlwm ntawm cov hlwb. Ntawm lawv, mannitol tuaj yeem txhim kho phagocytic kev ua haujlwm ntawm macrophages. Cistanche deserticola muaj ntau yam tshuaj lom neeg, ntawm cov glycosides ntawm Cistanche deserticola yog cov khoom siv tseem ceeb rau nws txoj kev tiv thaiv kab mob, thiab cov khoom xyaw tseem ceeb yog mannitol [35].

2.4 Inhibition ntawm neuronal apoptosis

Thaum lub sij hawm kev loj hlob ntawm lub paj hlwb, paj hlwb ua lub luag haujlwm tseem ceeb. Thaum cov paj hlwb apoptosis, nws tuaj yeem ua rau lub cev tsis ua haujlwm thiab kev paub tsis meej. Yog li ntawd, lub hom phiaj tseem ceeb ntawm kev tiv thaiv thiab kho kev puas hlwb yog los tiv thaiv cov hlab ntsha thiab ncua kev tuag neuronal. Cov txheej txheem ntawm neuronal apoptosis feem ntau suav nrog oxidative kev nyuaj siab thiab txo qis ntawm mitochondrial membrane peev xwm. Ju Bowei et al. [36] pom tias phenylethanolamine tuaj yeem txo A hauv hippocampus nas los ntawm kev kawm AD nas １－４２,Ａ Kev qhia ntawm 1-40 protein cuam tshuam A Cascade cov tshuaj tiv thaiv los tiv thaiv neurons thiab txhim kho cov kev kawm thiab kev nco muaj peev xwm ntawm AD nas. Kev tshawb fawb [37] qhia tias echinacoside tuaj yeem cuam tshuam qhov sib txuam ntawm ntau cov calcium uas tsis muaj nyob hauv cov cell uas tshwm sim los ntawm cov pa oxygen reactive, yog li ua rau cov teebmeem neuroprotective thiab txhim kho kev txawj ntse. Maorui paj glycoside yog ib qho activator ntawm Nrf2 thiab inducer ntawm HO-1 qhia. Los ntawm kev txhim kho ntawm HO-1, nws plays ib qho antioxidant thiab txo cov neurotoxicity, yog li inhibiting neuronal apoptosis thiab txhim kho kev kawm thiab kev nco muaj peev xwm [38]. Luo Lan et al. [28] pom los ntawm kev tshawb fawb tias tag nrho glycosides ntawm Cistanche deserticola tuaj yeem txo cov kab mob pathological ntawm cov neurons puas hauv CA1 cheeb tsam ntawm hippocampus ntawm kev sim AD nas, thaum tseem txo qis kev puas tsuaj rau ultrastructure ntawm hippocampal neurons, yog li txhim kho kev txawj ntse. Kev sim txhaj tshuaj A rau hauv ob sab hippocampus ntawm nas 25-35, nws yooj yim ua rau neuronal apoptosis hauv hippocampus. Miao Xin et al. [39] pom los ntawm kev tshawb fawb tias Cistanche deserticola poolside tuaj yeem tiv thaiv PC12 paj hlwb puas tsuaj los ntawm D-neneneba galactose thiab txhim kho kev txawj ntse. Nkauj Qingqing [8] tau ua qhov kev sim dej tshawb nrhiav ntawm tus nas qauv ntawm ob sab sib xws carotid artery ligation (2VO). Tus qauv nas ntawm 2VO tau ua rau puas tsuaj rau cov neurons hauv hippocampus. Tom qab muab Cistanche deserticola, HE staining thiab Nissl staining tau siv. Cov txiaj ntsig tau pom tias tsis muaj kev puas tsuaj rau cov neurons tom qab kev tswj hwm, qhia tias Cistanche deserticola muaj cov nyhuv neuroprotective, Yog li txhim kho kev kawm thiab kev nco muaj peev xwm [40].

2.5 Txo ischemic hlwb raug mob

Nyob rau hauv xyoo tas los no, qhov kev xav ntawm neurovascular tau nce zuj zus hauv kev teb rau kev paub tsis meej, tshwj xeeb tshaj yog Alzheimer's disease. Kev tshawb fawb [41] qhia tau hais tias neuronal cell apoptosis kuj tuaj yeem tshwm sim los ntawm cerebrovascular dysfunction, thiab ischemic hlwb raug mob tuaj yeem txo A Muaj peev xwm tshem tawm extracellular A nce sedimentation ua rau kev paub tsis meej. Cerebral ischemia-reperfusion raug mob feem ntau cuam tshuam nrog ntau yam kev sib txuas, suav nrog kev tso tawm ntawm excitatory amino acids (EAA), nce tsim cov dawb radicals, intracellular calcium ion instability, thiab muaj zog tiv thaiv kab mob. Nws yog ib qho nyuaj cascade cov tshuaj tiv thaiv. Xaiv cerebral ischemia nas thiab saib xyuas cov ntsiab lus ntawm aspartic acid nyob rau hauv lub hlwb cov ntaub so ntswg tom qab reperfusion. Nws tuaj yeem pom tau tias tag nrho glycosides ntawm cistanche tuaj yeem txo nws cov ntsiab lus, thiab tswj cov ntsiab lus ntawm EAA hauv lub paj hlwb cortex, yog li txo qis ischemic hlwb puas thiab txhim kho kev txawj ntse [6].

Superman tshuaj ntsuab cistanche-Anti Alzheimer tus kab mob

3 Cov ntsiab lus

Raws li paub zoo, Tuam Tshoj tau nkag mus rau lub neej laus, thiab Tuam Tshoj noj qab haus huv tau dhau los ua lub tswv yim hauv tebchaws. Alzheimer's disease, Lewy lub cev dementia, vascular dementia, thiab lwm yam kab mob nrog kev paub tsis meej raws li qhov tshwm sim tseem ceeb tau dhau los ua cov kab mob uas cuam tshuam rau lub cev thiab lub hlwb kev noj qab haus huv ntawm cov hnub nyoog nruab nrab thiab cov neeg laus, cuam tshuam rau lub neej zoo ntawm cov neeg mob, thiab ua rau muaj kev cuam tshuam loj heev. lub nra rau tsev neeg thiab zej zog. Yuav ua li cas txhawm rau txhim kho kev paub tsis meej yog qhov tseem ceeb ntawm kev tshawb fawb kho mob hauv ntau lub teb chaws, suav nrog Tuam Tshoj.Cistanche deserticola yog me me hauv qhov thiab saj. Kev tshawb fawb [22-24, 42-43] qhia tau hais tias Cistanche deserticola deserticola deserticola thiab nws cov extracts ua lub luag haujlwm zoo hauv ntau cov kab mob hauv tib neeg, tshwj xeeb tshaj yog hauv kev tiv thaiv thiab kho cov kab mob hauv paj hlwb, tshwj xeeb tshaj yog hauv kev txhim kho kev txawj ntse, thiab muaj kev nyab xeeb zoo. Cov ntshav-hlwb barrier plays lub luag haujlwm tseem ceeb hauv kev ruaj ntseg ntawm ib puag ncig sab hauv. Feem ntau cov tshuaj tsis tuaj yeem dhau los ntawm cov hlab ntsha-hlwb, uas txwv lub luag haujlwm ntawm lub paj hlwb. Txawm li cas los xij, qee cov khoom xyaw tseem ceeb ntawm Cistanche deserticola tuaj yeem ua tau zoo dhau los ntawm cov hlab ntsha hauv hlwb, yog li ua rau muaj txiaj ntsig zoo ntawm cov paj hlwb hauv nruab nrab [44]. Vim tias qhov bioavailability tsawg, kev siv tshuaj kho mob tsuas yog txwv rau qee qhov. Qee cov kev tshawb fawb tau sim los txhim kho cov kev npaj ib txwm muaj ntawm Cistanche deserticola los ntawm txoj kev xws li PhGs liposomes, nanoparticles, phospholipid complexes, thiab lwm yam raws li cov tshuaj suav tshuaj, los txhim kho nws cov bioavailability. Qhov no yuav muab cov tswv yim muaj txiaj ntsig rau kev tshawb fawb tob txog kev tiv thaiv thiab kho kev puas hlwb hauv Cistanche deserticola thiab muaj cov tshuaj suav tshuaj suav tshuaj.. Xib Fwb Yang Wenming tsim Zhinao Capsule, uas yog tsim los ntawm Cistanche deserticola ua ib qho tseem ceeb. Ntau qhov kev tshawb fawb [45-46] tau pom tias Zhinao Capsule muaj cov txiaj ntsig ntawm dilating cov hlab ntsha, antioxidant thiab tshem tawm cov dawb radicals, tiv thaiv hlwb hlwb thiab neurons, thiab yog li txhim kho kev txawj ntse.