Thaum twg Yog Lub Sijhawm Zoo Tshaj Plaws Rau Cov Neeg Mob Parkinson Kom Tau Txais Lub Hlwb Pacemaker (DBS)?

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Muaj ntau cov lus qhia nyob rau hauv lub teb ntawmParkinson tus kab mobkev kho mobnyob hauv lub ntiaj teb, suav nrog World Movement Disorders Association MDS cov lus qhia, American AAN cov lus qhia, European Union EFNS cov lus qhia, thiab British NICE cov lus qhia. Ntawm lawv, MDS cov lus qhia yog qhov kev ntseeg siab tshaj plaws, vim tias MDS tseem ceeb heev rau qhov kev ntsuam xyuas zoo ntawm txhua qhov kev sim tshuaj, thiab cov qauv ntsuas yog 24 yam, thiab ntsuas qhov ua tau zoo. Science paub tsis muaj ciam teb.Parkinson tus kab mobkab mobtau nthuav dav thoob plaws ntiaj teb, thiab cov kev kho mob zoo sib xws. Nyob rau hauv ib puag ncig uas muaj ntau cov lus qhia, tsis tas yuav tsum muaj ntau cov lus qhia txog kev kho mob hauv Suav. Rau kev kuaj mob ntawmParkinson tus kab mobkab mob, Tuam Tshoj tsis muaj cov txheej txheem kuaj mob tshwj xeeb, tsis yog Europe lossis Tebchaws Meskas. Yuav luag tag nrho lub ntiaj teb no siv cov txheej txheem kuaj mob ntawm British Brain Bank. Muaj me ntsis haiv neeg txawv nyob rau hauvParkinson tus kab mobkab mob. Kab rov tav, qhov zoo sib xws yog siab heev. Vertically, ntau cov lus qhia txawv teb chaws tsuas yog hloov kho thiab ntxiv me ntsis tom qab xyoo 2006, thiab tsis muaj qhov hloov pauv loj. Los ntawm qhov kev pom ntawm kev ua tau zoo, nws tuaj yeem sib koom ua ke tag nrho hauv ntiaj teb, txhua tus txais yuav MDS cov txheej txheem ntawm Lub Koom Haum Ntiaj Teb Kev Tsis Txaus Siab, Suav version yog txaus rau Suav, thiab nws yog siv los ua ke nrog cov xwm txheej hauv Suav teb.

Nyem rau Cistanche extract hmoovrau tus kab mob Parkinson

Hauv thaj teb ntawmParkinson tus kab mobkab mobkev kho mobnyob rau Suav teb, muaj ib lo lus hais tias: "Cov dej me me yuav ntws tsis nrhiav kev ua tiav". Xws li cov lus tsis yog tag nrho raws li kev tshawb fawb tab sis muaj xim kab lis kev cai muaj zog: nws yog qhov zoo dua kom tuag dua li kev ua neej nyob. Thaum ntxov xyoo, ntau tus neeg txhawj xeeb txog cov kev mob tshwm sim ntawm cov tshuaj dopamine, feem ntau ncua kev pib tshuaj. Muaj cov kws kho mob uas muaj kab mob ntau tshaj 10 xyoo, uas twb yog cov neeg mob H&Y qib 5 hnyav tshaj plaws, thiab tseem muaj kev cuam tshuam los ntawm ncua sij hawm noj tshuaj, ntshai tias cov tshuaj "tshuaj lom heev". Nrog rau lub sijhawm ntev, cov nyhuv ntawm cov tshuaj dopamine poob qis, thiab cov laj thawj tseem ceeb rau cov kev mob tshwm sim yog apoptosis ntawm dopamine receptor postsynaptic membrane thiab txo qis ntawm lub peev xwm ntawm cov presynaptic membrane tso tawm vesicles, uas tsis muaj dab tsi ua nrog. kev siv tshuaj dopamine. Kev kho tshuaj rau tus kab mob Parkinson yuav tsum tau pib sai li sai tau rau cov laj thawj hauv qab no: 1. Kev cuam tshuam ntxov tuaj yeem txhim kho lub cev muaj zog thiab lub neej zoo; 2. Kev loj hlob ntxov ntawm tus kab mob Parkinson yog sai dua li theem lig, tej zaum yog vim muaj cov txheej txheem them nyiaj tsis zoo nyob rau theem pib; 3. Thaum ntxov ntawm Parkinson tus kab mob kev loj hlob Kev pib ntawm kev kho mob cov tsos mob tej zaum yuav cuam tshuam qhov kev pab cuam deleterious. Rau cov kab mob neurodegenerative xws li Parkinson's disease, yav tom ntej ntawm kev tshawb fawb yog nyob rau hauv kev kuaj mob ntxov thiab kev kho mob ntxov. Thaum tus neeg mob tsim cov tsos mob, ntau tshaj li ib nrab ntawm cov dopaminergic hlwb nyob rau hauv lub basal ganglia ntawm lub hlwb twb tuag lawm. Yog tias tsuas yog 20 feem pua ​​​​ntawm cov dopaminergic hlwb tseem nyob, cov kws kho mob tuaj yeem ua dab tsi ntxiv?

CISTANCHE TUBULOSA SLICES

Txoj kev tshawb fawb EarlyStim luam tawm nyob rau hauv New England Journal of Medicine hauv 2013 yog qhov loj-loj ob-dig muag randomized tswj kev sim ua nyob rau hauv Fabkis thiab lub teb chaws Yelemees. Qhov nruab nrab ntawm tus kab mob yog 7 xyoo, thiab luv tshaj yog 3 xyoo. Kev ua tau zoo ntawm DBS ntxiv rau pab pawg kho mob tau zoo dua li ntawm pawg tshuaj ib leeg. . Qhov kev pom yav dhau los yog DBS phais yuav tsum tau ua 4 xyoos tom qab tus neeg mob pib, vim tias 4- xyoo kab mob txaus los txiav txim seb tus neeg mob puas muaj Parkinson's disease lossis Parkinson's syndrome. Nrog rau kev txhim kho thev naus laus zis, xws li PDRD lub hlwb ntsig txog lub network tsim los ntawm FDG PET-CT, kev txheeb xyuas qhov tseeb ntawm Parkinson's disease thiab Parkinson's syndrome tau tshaj 80 feem pua, thiab cov kab mob ntev li 4 xyoos tsis yog qhov pib ntawm kev kuaj mob. Kev tshawb fawb txog kev kho DBS hauv cov neeg mob uas muaj kab mob nruab nrab ntev dua 7 xyoo tam sim no tab tom ua hauv Europe.

Cistanche extracttuaj yeem txo Parkinson's syndrome

3-5 xyoo yog lub sijhawm honeymoon ntawm kev kho tshuaj, thaum tus neeg mob zoo, puas tsim nyog phais? Cov lus nug ntawm no yog tias DBS zoo heev hauv kev kho cov tsos mob, thiab nws yeej cov tshuaj hauv kev kho mob ntawm cov tsos mob hloov pauv thiab dyskinesia. Puas yog DBS muaj cov teebmeem neuroprotective thiab ncua kev kis kab mob? Nws yog ib qho nyuaj rau kev paub qhov txawv ntawm kev tiv thaiv thiab kho cov teebmeem ntawm kev tshawb fawb, thiab cov pov thawj ntawm kev tiv thaiv los ntawm cov tshuaj tiv thaiv xws li pramipexole, selegiline, rasagiline, high-dose vitamin E, coenzyme Q10, thiab lwm yam. . Txaus thiab feem ntau pov thawj rau qhov tsis sib xws tshwm sim. Cov lus qhia hloov kho xyoo no tshem tawm cov kev coj ua ntawm kev sib cais cov tshuaj tiv thaiv thiab cov tshuaj tiv thaiv kab mob hauv qhov thib ob tsab ntawm 2009 cov lus qhia, vim tias txawm tias cov tshuaj tsuas txhim kho cov tsos mob thiab txhim kho tus neeg mob lub cev muaj peev xwm thiab lub siab xav, nws yuav ua rau txo qis kev kis kab mob. ceev. Qhov zoo ntawm DBS hauv kev txhim kho lub cev muaj zog thiab txhim kho lub neej zoo yog qhov sib piv nrog cov tshuaj. Yog tias lub sijhawm honeymoon ntawm kev kho tshuaj tsis qab zib, DBS tuaj yeem ua rau cov neeg mob xis nyob.

Lub Koom Haum Ntiaj Teb Kev Tsis Txaus Siab MDS hauv xyoo 2011 tau teev ob sab subthalamic nucleus DBS, ob sab globus pallidus DBS, thiab unilateral globus pallidus lesions ua pov thawj siab tshaj plaws. Piv nrog rau xyoo 2009, qhov thib peb tsab ntawm 2014 Suav cov lus qhia tsis tau hloov pauv ntau hauv cov kev kho mob phais. Nws tseem pom zoo tias kev ua haujlwm ua ntej levodopa rhiab heev tuaj yeem siv los ua qhov ntsuas ntsuas rau kev kho DBS (qib pov thawj B). Cov neeg mob uas muaj hnub nyoog yau thiab cov kab mob luv luv tuaj yeem txhim kho ntau dua. Qhov tseem ceeb (qib pov thawj C), tsis muaj pov thawj rau GPI DBS thiab VIM DBS los ua qhov kev pom zoo prognostic (qib pov thawj U). Xws li kev pom tsis tsim nyog hauv Suav cov lus qhia yuav ua rau cov kws kho mob thiab cov neeg mob yuam kev.

Yog tias tus neeg mob yuav tsum tau tos kom txog thaum cov tshuaj kho tau tag, thiab cov hlwb dopamine tseem tshuav tsawg dua 10 feem pua ​​​​ua ntej nrhiav kev kho mob phais, ces peb tsuas tuaj yeem nplij tus neeg mob: nws yog qhov zoo dua kom tuag dua li kev nyob. Tau ntsib nrog cov txheej txheem kho mob zoo li no, peb xav ceeb toom cov neeg mob Parkinson tus kab mob tias yog tias koj vam tias yuav muaj lub neej zoo, kev phais DBS ntxov yuav pab tau lawv ntau dua.

Lus Cim: Cov tshuaj suav tshuaj suav tshuaj ntsuab cistanche (tseem hu ua "daj tshuaj ntsuab" thiab "tso suab puam ginseng"), loj hlob tsuas yog hauv cov suab puam qhuav thiab sov. Raws li ib qho ntawm cuaj cov tshuaj tsis txawj tuag, Cistanche (cistanche tubulosa / cistanche deserticola / desertliving cistanche / cistanche salsa) cov ntsiab lus nrog cov khoom xyaw nplua nuj xws li echinacoside, acteoside, tag nrho phenylethanoid glycosides, flavonoids, polysaccharides, thiab lwm yam. nourishing tshuaj ntsuab thiab khoom noj khoom haus rau tib neeg lub cev tiv thaiv kab mob, cov kab mob hauv nruab nrog cev, thiab hlwb hlwb thiab neurons, thiab lwm yam. Cov kev tshawb fawb tshuaj niaj hnub no tau lees paub cov txiaj ntsig ntawm cistanche (cov txiaj ntsig ntawm cistanche): txhim kho kev tiv thaiv; txhim kho kev ua haujlwm ntawm kev sib deev thiab lub raum ua haujlwm; tiv thaiv qaug zog; anti-aging; txhim kho kev nco; anti-Parkinson tus kab mob; anti-Alzheimer tus kab mob; antioxidation; yooj yim- cem quav; anti-inflammatory; txhawb cov pob txha loj hlob, ua kom tawv nqaij dawb; tiv thaiv daim siab; lwm.