Hu rau: jerry.he@wecistanche.com

Tus kab mob Parkinsonyog ib tug kab mob ntawm lub hauv nruab nrab lub paj hlwb uas tshwm sim nyob rau hauv nruab nrab-hnub nyoog thiab cov neeg laus. Hauv cov neeg muaj hnub nyoog tshaj 60 xyoo, qhov tshwm sim feem ntau yog kwv yees li 10 feem pua, thiab muaj qhov sib txawv me ntsis ntawm Tuam Tshoj thiab txawv teb chaws.

Cistanche zoo heev rau Parkinson tus kab mob

1. Muaj feem cuam tshuam ntawm cov tshuaj feem ntau ntawm cov kab mob Parkinson

1 Neuropsychiatric phiv

L-dopa-induced hallucinations yog ib qho kev mob tshwm sim, txawm tias tsis tshua muaj kev kho mob thaum ntxov. Qee cov kev tshawb fawb qhia tias thawj ob xyoos ntawm kev kho levodopa, qhov tshwm sim ntawm kev hnov ​​​​lus tsuas yog 3.3 feem pua, tab sis nrog lub sijhawm ntev ntawm cov tshuaj, qhov tshwm sim ntawm kev hnov ​​​​lus kuj nce ntxiv. Tsis tas li ntawd, cov neeg mob laus kuj muaj feem ntau rau kev hnov ​​​​lus.

Tsis tas li ntawd, COMT inhibitors, selegiline, amantadine, thiab cov tshuaj anticholinergic kuj tau tshaj tawm tias ua rau pom kev. L-dopa, tag nrho cov dopamine agonists, thiab anticholinergics muaj peev xwm ua rau muaj kev cuam tshuam ntawm kev nco qab, tshwj xeeb tshaj yog nyob rau hauv cov neeg laus thiab cov neeg muaj kev puas hlwb. Cov tshuaj Anticholinergic feem ntau ua rau muaj kev puas siab puas ntsws, nrog rau kev nco tsis tau, txo qis concentration, thiab lub ntsej muag lobe tsis ua haujlwm.

2 pw tsaug zog

Tus kab mob Parkinsonnws tus kheej kuj yog ze ze rau kev pw tsaug zog, yog li thaumParkinson tus kab mobcov neeg mob muaj kev pw tsaug zog tsis zoo, nws yog ib qho nyuaj rau txiav txim seb qhov kev ua tau zoo yog vim qhov kev loj hlob ntawm tus kab mob nws tus kheej los yog cov kev mob tshwm sim ntawm kev tiv thaiv.Parkinson tus kab mobtshuaj. Piv txwv li, qhov tshwm sim ntawm kev pw tsaug zog nyob rau hauv PD nce nrog cov neeg mob hnub nyoog, koob tshuaj levodopa, thiab qhov tshwm sim ntawm "on-off phenomenon". Feem ntau hais lus, thaum nws los txog rau kev pw tsaug zog mob tshwm sim los ntawm cov tshuaj tiv thaiv Parkinson tus kab mob, thawj yam peb xav txog yog selegiline. Nws yog feem ntau ntseeg tias nws yuav tsum tau noj ua ntej tav su, thiab luv luv, nws yuav tsum tsis txhob noj thaum yav tsaus ntuj thiab yav tsaus ntuj. Qhov tseeb, levodopa thiab tag nrho cov dopamine agonists tuaj yeem cuam tshuam nrog insomnia. Tsis tas li ntawd, amantadine kuj tseem tuaj yeem ua rau pw tsaug zog. Kev pw tsaug zog ntau dhau nruab hnub yog qhov tshwm sim hauvParkinson tus kab mobcov neeg mob. Kev tshawb fawb txog kab mob kis tau qhia tias 16 feem pua ​​​​ntawm cov neeg mob Parkinson tuaj yeem muaj tus mob no, uas tej zaum yuav cuam tshuam txog kev kis kab mob. Kev kho mob nrog levodopa yog txuam nrog kev puas hlwb.

3 Kev mob plab hnyuv

Kev xeev siab thiab ntuav yog qhov tshwm sim ntawm plab hnyuv loj ntawm cov tshuaj antiparkinsonian, tab sis tsis tshua muaj tshwm sim hauv kev kho tsis tau.Tus kab mob Parkinsoncov neeg mob. Txog li 80 feem pua ​​​​ntawm cov neeg mob yuav muaj anorexia, xeev siab, ntuav thiab epigastric tsis xis nyob, kub hnyiab, tsam plab thiab lwm yam tsos mob thaum lawv pib siv levodopa.

Tsis tas li ntawd, yuav luag txhua cov tshuaj antiparkinsonian muaj peev xwm ua rau xeev siab, suav nrog selegiline, tag nrho cov dopamine agonists, thiab COMT inhibitors tolcapone thiab entocapone. Anorexia yog qhov tshwm sim ntau dua ntawm tolcapone thiab selegiline. Qhov kev mob tshwm sim no tuaj yeem ua rau lub cev poob qis. Kev mob raws plab yog qhov tshwm sim tsis zoo uas tsis yog dopaminergic thaum cov neeg mob tau kho nrog COMT inhibitors, thiab tuaj yeem tshwm sim txawm tias tom qab cov neeg mob tso tseg cov tshuaj. Cov ntawv tshaj tawm kuj tau tshaj tawm tias entacapone thiab darlingfu (stalevo, sib xyaw ntawm entacapone, carbidopa, thiab levodopa) tuaj yeem ua rau mob plab.

Levodopa thiab dopamine agonists feem ntau ua rau orthostatic hypotension. Tsis tas li ntawd, ergot alkaloids thiab non-ergot agonists ntawm dopamine receptors tuaj yeem ua rau cov ntshav siab poob qis, txawm tias cov tsos mob tshwm sim tsuas yog ib feem me me ntawm cov neeg mob, thiab cov lus teb no tshwm sim thawj zaug, yog li Dopamine agonists yuav tsum pib me me. koob tshuaj thiab titrated maj mam. Ntawm cov dopamine agonists, pramipexole yog tib cov tshuaj uas tau txiav txim siab tsis pub muaj orthostatic hypotension hauv monotherapy. Ob leeg selegiline thiab COMT inhibitors (tocapone thiab entocapone) tuaj yeem ua rau orthostatic hypotension.

Nws yog ib qho tseem ceeb rauParkinson tus kab mobcov neeg mob nrhiav kev kho mob rau lawv!

Kev siv tshuaj yeeb tshuaj yog qhov txuas tseem ceeb tshaj plaws hauv kev tawm tsamTus kab mob Parkinson. Kev noj tshuaj yog txheej txheem ntev, thiab ntau "them nyiaj" muaj kev txhawj xeeb txog cov tshuaj vim lawv txhawj xeeb txog cov kev mob tshwm sim ntawm cov tshuaj sab hnub poob. Qhov tseeb, nrog rau kev txhim kho cov cuab yeej siv kho mob, cov tshuaj sab hnub poob thiab cov tshuaj suav tshuaj tau ua rau muaj txiaj ntsig zoo rau kev kho mobTus kab mob Parkinson. Yog tias cov tshuaj Western tsis zoo, nws tuaj yeem kho nrog cov tshuaj suav tshuaj, thiab qee zaum cov tshuaj suav tshuaj tuaj yeem tsim "cov teebmeem txuj ci tseem ceeb". Raws li cov txheej txheem ib txwm siv ntawm cov tshuaj suav tshuaj, Dr. Wang Shilong qhov kev kho mob hauv kev kho mobParkinson tus kab mobcov neeg mob rau 20 xyoo tau sau tseg. , tuaj yeem zam cov kev mob tshwm sim los ntawm cov tshuaj sab hnub poob!

Peb theem ntawm kev kho mob:

Thawj theem yog tsuas yog ua kom lub siab ua kom lub siab thiab ua kom cua txias, ua kom lub siab tsis zoo yang, thiab txo cov kev tsis txaus siab tseem ceeb. Tsim kev ntseeg siab rau cov neeg mob kom kov yeej lawv cov kab mob.

Cov kauj ruam thib ob yog kev noj qab haus huv raum, noj cov ntsiab lus, txhawb cov ntshav thiab txhawb cov yin, tshem tawm lub hauv paus rau kev tsim cov tsos mob, thiab nrhiav tus kab mob. Pib los ntawm qhov chaw thiab sib sau ua ke cov nyhuv curative.

Qhov thib peb kauj ruam yog tswj lub zang-fu lub cev thiab sib npaug yin thiab yang. Cov lus qub "yin thiab yang yog zais cia, thiab tus ntsuj plig tuaj yeem kho tau", "kev ncaj ncees khaws cia hauv lub cev, thiab kev phem tsis tuaj yeem qhuav". tiv kev phem