Cov nyhuv ntawm Cistanche rau tso zis ntawm lub raum tsis ua haujlwm nas

Hu rau:joanna.jia@wecistanche.com/ WhatsApp: 008618081934791

Cov nyhuv ntawm Cistanche rau tso zis ntawmnoj qab nyob zoonas thiab nas nrog raum tsis ua haujlwm

Shen Lianzhong Zhong Xiaoyan Wang Shuxian

【Cov ntsiab lus】Lub Hom Phiaj: Saib xyuas cov nyhuv ntawmCistanchentawmtso zisnyob rau hauv txiv neej Healthy nas thiab raum tsis ua hauj lwm nas. Method: Muab Healthy txiv neej nas ib igCistanche, sau thiab ntsuas cov zis tawm ntawm lub sijhawm sib txawv tom qab kev tswj hwm; siv im hydrocortisone los tsim lub raum tsis ua haujlwm nas qauv, thiab txuas ntxiv igCistancheNyob rau tib lub sijhawm, sau thiab ntsuas tom qab kev tswj hwm zaum kawg Cov zis ntau lub sijhawm, thiab ntsuas lub cev hnyav thiab qhov hnyav ntawm cov khoom nruab nrog cev. Cov txiaj ntsig: Txiv neej Healthy nas ib zaug igCistanche10g/kg thiab 20g/kg ua kom cov zis tso zis ntau ntxiv ntawm 0-1 teev thiab 1-2 teev tom qab kev tswj hwm. Contrary to the effect on Healthy nas, muab nas nruam igCistancherau 10 hnub tau txo qis qhov tso zis ntau ntxiv hauv 0-1 teev thiab 1-2 teev tom qab koob tshuaj kawg ntawm lub raum tsis ua haujlwm nas, thiab nce qhovtso zisntawm raum tsis ua hauj lwm nas. Lub cev hnyav thiab qee qhov hnyav ntawm lub cev. Xaus:Cistanchemuaj txawv regulating cuam tshuam rau lubtso zisntawm Healthy nas thiab raum tsis ua hauj lwm nas.

Ntsiab lus: Cistanche; tso zis; hydrocortisone

CistancheYCMa yog lub cev qia ntawmCistanco, tshuaj suav tshuaj rau kev txhim kho raum ua haujlwm. Nws muaj cov teebmeem ntawm nourishing lub raum, nourishing essence thiab moisturizing cov hnyuv. "Materia Medica" yog hu ua cov tshuaj tseem ceeb rau kev ntxiv cov ntsiab lus thiab cov ntshav thiab txhawb lub raum. Nws muaj txiaj ntsig zoo rau kev qaug zog, tsis nco qab, tsis hnov ​​​​lus, thiab enuresis tshwm sim los ntawm lub raum tsis txaus.CistancheNws kuj tseem siv tau rau tib neeg los kho senile urinary disorder (ntau zaustso zis, tso zis ntau zaus,tso zis). Ceev ceev, tso zis, thiab lwm yam). Cov kev tshawb fawb niaj hnub no tau qhia tiasCistanchemuaj qee yam kev tiv thaiv kev laus [1, 2], thiab nws tag nrho cov extract muaj cov teebmeem ntawm kev txhim kho lub cev tiv thaiv kab mob [3, 4] thiab inhibiting lipid peroxidation [4, 5]. Muaj cov ntawv ceeb toom ntawm kev sim kev tshawb fawb txog qhov cuam tshuam ntawmCistanche[91], tab sis tsis muaj lus ceeb toom txog nws qhov cuam tshuam rau tsiajtso zistau pom. Kab lus no tham txog nws cov nyhuv rautso zisnyob rau hauv lub raum tsis ua hauj lwm nas.

Cistanche

1 khoom

1.1 Test tshuaj:

Cistanchepastes 2.5 g / ml, batch naj npawb 901127, muab los ntawm Natural Medicine Laboratory ntawm Tuam Tshoj Medical Research thiab Development Center.

1.2 Tsiaj

Tsis txhob siv Wistar nas, yuav los ntawm Tsiaj Department ntawm Beijing Medical University.

2 Cov txheej txheem thiab cov txiaj ntsig

2∙1 Cov nyhuv ntawm cov zis tso zis ntawm Healthy nas

Yuav kom txo tau tus kheej qhov sib txawv ntawm covtso zisntawm cov tsiaj, "rats ig ib txwm dej 2∙5ml / 100g thiab tom qab ntawd sau cov ntim hauv 2 teev.tso zisntim nce mus txog ntau dua 40 feem pua ​​​​ntawm gavage ntim raws li cov tsiaj sim. Peb caug txiv neej nas hnyav 231 ± 19g tau muab faib ua 3 pawg raws li lawv lub cev hnyav. ' Tom qab 24 teev ntawm kev yoo mov thiab dej, ig 3. Tom qab ntawd, cov tsiaj hauv txhua pab pawg tau muab cov tshuaj ua kua los yog qhov sib npaug ntawm cov ntsev ib txwm ntawm lub cev hnyav ntawm 2.0ml / 100g. Muab cov tsiaj tso rau hauv lub tawb metabolic, ib qho rau txhua lub tawb, thiab sau cov zis ntawm 0-1, 1-2, 2-4, 4-6 teev tom qab tswj hwm, thiab ntsuas qhov ntim. Cov txiaj ntsig tau pom tias cov zis ntim ntawm lubCistanchepab pawg tau siab dua li ntawm pawg tswj hwm hauv 2 teev (0-1h, 1-2h) tom qab tswj hwm (saib Table 1).

Table 1Cov teebmeem ntawm Cistanche ntawm cov zis tso zis ntawm ib txwm txiv neej nas

2∙2 Effect ontso zisntawm nas nrog raum tsis ua haujlwm

40 txiv neej nas hnyav 350±4{{10}}g, muab faib ua 4 pawg raws li lub cev hnyav, tshwj tsis yog rau pawg tswj hwm dawb huv, im sterilized saline {{ 18}}.3ml / 100g ib hnub twg, tag nrho lwm pab pawg tau txhaj tshuaj nrog qhov sib npaug ntawm 0.5 feem pua ​​​​ hydrocortisone Tib lub sijhawm, muab cov tshuaj lossis qhov sib npaug ntawm cov kua qaub ib txwm 1∙0ml / 100g rau 10 hnub. 30 feeb ua ntej koob tshuaj zaum kawg, ig 3.0ml / 100g ib txwm saline load rau 30 feeb, nyem tus nas lub plab plab kom khoob lub zais zis ntau li ntau tau, thiab tom qab ntawd muab tshuaj. Tom qab siv tshuaj, muab tus nas tso rau hauv txhua lub tawb thiab muab cov tsiaj tso tom qab muab tso rau hauv lub tawb metabolic, cov zis tso zis tau sau rau 0 mus rau 1 teev, 1 mus rau 2 teev, 2 mus rau 4 teev, thiab 4 mus rau 6 teev tom qab. kev tswj hwm. Tom qab ntawd ntsuas lub cev qhov hnyav, thiab ntsuas cov thymus, qog adrenal, prostate, cov hlab ntsha, cov qog ntshav, thiab zais zis tom qab tua. Cov txiaj ntsig tau pom tias cov zis tso zis ntawmCistanchentawm 0-1 teev thiab 1-2 teev tau qis dua li ntawm pawg hydrocortisone; tustso zistso zis ntawmCistanche10g/kg pab pawg ntawm 2-4 teev thiab 4-6 teev qis dua li ntawm hydrocortisone (saib Daim duab 2). Qhov hnyav ntawm nas nyob rau hauv pawg hydrocortisone raum tsis ua haujlwm thiab qhov hnyav ntawm thymus, qog adrenal, cov qog ntshav, thiab lwm yam kabmob tau txo qis.Cistanchetuaj yeem nce qhov hnyav, qog adrenal, cov hlab ntsha hauv lub cev, thiab cov qog ntshav ntawm lub raum tsis ua haujlwm nas qhov hnyav (saib Table 3).

Rooj 2Cov teebmeem ntawm Cistanche ntawm cov zis tso zis ntawm nas raum tsis ua haujlwm

Table 3Cov teebmeem ntawm Cistanche ntawm lub cev hnyav thiab lub cev hnyav ntawm nas nrog raumua tsis tiav

3 Kev sib tham

Cov tshuaj suav tshuaj suav hais tias "lub raum tswj hwm dej," lub zais zis ntawm lub zais zis, triple-burner thiab excretion ntawm dej thiab kua tag nrho yog nyob ntawm qhov kub ntawm lub raum. Kev tswj tsis tau tso zis (frequenttso zis, ceev ceev, incessanttso zis, nocturia, thiab lwm yam) yog tshwm sim los ntawm lub raum tsis txaus yang thiab txias nyob rau hauv qis Jiao. Nws muaj ntau dua nyob rau hauv cov neeg laus hnub nyoog nruab nrab thiab cov neeg laus. ' Yog li ntawd, kev kho cov zis tawm ntawm cov zis yuav tsum tsom mus rau kev txhim kho lub raum ua haujlwm. Tom qab intramuscular txhaj ntawm hydrocortisone nyob rau hauv nas, lub cev hnyav ntawm lub raum tsis ua hauj lwm qauv pawg tau txo qis, thiab adrenal thiab gonadal coefficients tau txo qis. ``Thiab cov zis tso zis hloov pauv hauv 0~ 1 teev (tus tsiaj qhov hnyav sib txawv ntawm txhua pab pawg yog qhov tseem ceeb, yog li nws yuav tsum tau hloov los ntawm qhov hnyav) piv nrog Pab Pawg Tswj Xyuas Kev Noj Qab Haus Huv ntawm nas. ib igCistanchemuaj qhov pom tseeb los tiv thaiv qhov hnyav, adrenal thiab gonadal coefficient poob qis thiab lwm yam tsos mob ntawm lub raum tsis ua haujlwm. ' Cov zis tso zis ntawm ob pawg koob tshuaj ntawmCistanchetsis pub dhau 0 mus rau 1 teev thiab 1 mus rau 2 teev tom qab kev tswj hwm tau qis dua li ntawm pawg neeg lub raum tsis ua haujlwm, thiab muaj qee qhov kev sib raug zoo ntawm cov tshuaj. Cov zis tso zis ntawm lubCistanche10g / kg pawg hauv 2-4h thiab 4-6 teev tau siab dua li ntawm pawg hydrocortisone, uas tej zaum yuav tshwm sim los ntawm qhov tsis muaj zog ntawm cov tshuaj.

Cov txiaj ntsig ntawm kev tshawb fawb nrog Healthy nas qhia tias "Cistanchemuaj kev txhawb nqatso zishauv Healthy nas. "Qhov no yog raws li peb daim ntawv tshaj tawm dhau los [7] uasCistanchetxhawb lub zais zis tso zis. 'Contrary to the result oftso zisntawm raum tsis ua hauj lwm nas.Cistanchemuaj ob qho kev sib txawv kiag li ntawmtso zisntawm Healthy nas thiab raum tsis ua hauj lwm nas. "Ua ntej, nws yuav tsum tau piav qhia los ntawm kev nce cov zis tso zis ntawm nas tom qab lub raum tsis ua haujlwm: nas im hydrocortisone tuaj yeem ua rau lub raum tsis ua haujlwm. Cov nas tsuag tau tso zis ntau ntxiv, uas tej zaum yuav zoo ib yam nrog qee cov tsos mob ntawm qhov chaw kho mob tso zis tsis tswj.Cistancheua rau lub raum tsis ua hauj lwm Tsiaj txhu tau txo cov zis tso zis, "Qhov no yog raws li ib txwm suav tshuaj uasCistanchetxhim kho lub raum ua haujlwm. Tau kawg, txawm tias qhov nce ntawm cov zis tso zis tom qab lub raum tsis ua haujlwm los ntawm hydrocortisone muaj feem cuam tshuam nrog cov tsos mob ntawm cov zis tawm ntawm kev tswj hwm tseem yuav tsum tau lees paub los ntawm kev sim ntxiv. "Yog tias qhov tshwm sim yog qhov zoo," qhov no kuj tseem yuav yog tus qauv tshuaj tsiaj zoo rau cov kab mob tso zis tawm hauv cov tshuaj suav tshuaj.

Qhov thib ob, nws muaj kev txhawb nqa rau cov tsiaj noj qab haus huv. Txawm hais tias cov tsiaj uas siv yog cov nas tsaug zog thiab cov tshuaj loog uas siv rau hauv cov ntawv tshaj tawm dhau los [7] yog nyob rau hauv ib lub xeev sib txawv, "ob qhov kev ntsuam xyuas no yog tag nrho cov tsiaj txhu, cov kev ntsuam xyuas luv luv, yog li lawv muaj txiaj ntsig zoo, cov txheej txheem yuav tsum ua kom zoo ib yam, thiab cov tib yam yuav tsum tau.Cistanchemuaj ob qhov cuam tshuam rau cov tsiaj sib txawv (ib qho yog Healthy thiab lwm yam yog tus qauv tsiaj mob). "Qhov no kuj tseem tuaj yeem ua pov thawj tias cov tshuaj suav tshuaj suav nrog kev mob siab rau kev sib txawv thiab kev kho mob.

Cov teebmeem ntawm cistanche ntawm tso zis

Cov ntaub ntawv

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