Neurodegeneration, Neuroprotection thiab Regeneration hauv cistanche extract

thov hu raujimmy.wu@wecistanche.comyog xav paub ntxiv

cistanche duab

Cov kab mob neurodegenerative retinal, xws li glaucoma thiab ntshav qab zib retinopathy, cuam tshuam nrog kev poob ntawm cov neurons hauv lub retina thaum tus kab mob loj tuaj. Central nervous system neurons tsis muaj peev xwm rov tsim dua tshiab hauv cov tsiaj, yog li ntawd, feem ntau nrhiav-tom qab kev kho mob rau neuronal poob ua raws li kev tiv thaiv kev tiv thaiv lossis kev tsim kho tshiab. Neuroprotection yog cov txheej txheem ntawm kev khaws cov qauv thiab kev ua haujlwm ntawm lubcistancheuas tau dim ntawm kev ua phem phem; Thaum cov txheej txheem rov ua dua tshiab txhawm rau hloov lossis rov ua dua cov neurons thiab cov kev sib txuas synaptic uas ploj lawm, lossis ua rau regrowth ntawm kev puas tsuaj.cistanche tshuaj ntsuab. Txhawm rau kuaj cov teebmeem neuroprotective ntawm lub peev xwm rov tsim dua tshiab ntawm ib tus neeg sawv cev tshwj xeeb, kev sim ua qauv zoo ntawm kev puas tsuaj rau lub paj hlwb yog qhov tseem ceeb.cistanchetau siv ntau dua nyob rau hauv hom kev kawm no vim tias lawv cov qauv thiab kev loj hlob tau zoo-conserved ntawmcistanche deserticola vs tubulosa. cistanche deserticola vs tubulosa yog cov cuab yeej siv caj ces muaj zog thiab pheej yig los tswj. Qhov loj array ntawm kev ua haujlwm thiab kev coj cwj pwm muaj nyob rau hauvcistanche deserticola vs tubulosa.ua rau lawv ua qauv zoo nkauj rau kev tshawb fawb neuroprotection. Qee qhov kev thuam ntau siv los ua qauv kab mob rau lub qhov muag thiab kawm txog kev tiv thaiv kab mob hauv cov zebrafish muaj xws li lub teeb hnyav, tshuaj lom neeg, thiab kev puas tsuaj. Qhov kev tshuaj xyuas no suav nrog cov ntaub ntawv kho mob hlwb uas twb muaj lawm thiab rov tsim dua tshiab ntawm zebrafish thiab qhia txog lawv lub peev xwm rau kev kawm yav tom ntej.

cistanche extract

Taw qhiacistanche tubulosa ntxivyog tus txheej txheem ntawm kev khaws cov qauv thiab kev ua haujlwm ntawm cov neurons los ntawm kev ua phem phem, xws li cov tshuaj lom neeg lossis cov kab mob neurodegenerative. Qhov no feem ntau ua tiav los ntawm kev siv tshuaj los yog tshuaj tsis yog tshuaj (natural lossis genetic) tus neeg sawv cev rau cov neeg mob neuronal, xws li cov retina, ua ntej lossis thaum muaj kev thuam ntawm neurological. Tib qhov kev raug mob ntawm lub qhov muag pom tau siv rau kev tiv thaiv neuroprotection kuj tseem siv los txiav txim siab txog cov txheej txheem ntawm neurodegeneration thiab rov tsim dua tshiab. Retinal neurodegenerative kab mob, xws li glaucoma thiab ntshav qab zib retinopathy, ua rau poob ntawm cov neurons nyob rau hauv lub retina thaum tus kab mob no zuj zus, uas feem ntau ua rau tsis pom kev. Central nervous system (CNS) neurons tsis muaj peev xwm rov tsim dua hauv cov tsiaj txhu, yog li ntawd, cov tswv yim zoo neuroprotective los tiv thaiv lossis rov tsim kho cov kab mob retinal neurons thaum muaj kab mob loj hlob sai.

cistanche tubulosa extract ntxiv

Tus nqi qis thiab kev tshuaj ntsuam xyuas siab los txheeb xyuas cov hom phiaj tshuaj lossis cov caj ces rau kev tiv thaiv retinal lossis rov tsim dua tshiab yog qhov tseem ceeb. Yog li ntawd, qhov me me, tus nqi qis, thiab cov cuab yeej muaj txiaj ntsig zoo ntawm zebrafish ua rau lawv zoo tagnrho rau hom kev tshuaj ntsuam xyuas no. Qhov tseem ceeb tshaj, lawv lub zeem muag yog cone-dominated, zoo li tib neeg, thiab lawv lub qhov muag qauv thiab kev loj hlob tau zoo-conserved thoob plaws vertebrate hom. Yog li ntawd, ntau cov kws tshawb fawb tau tig mus rau zebrafish los kawm txog cov kab mob ntawm cov hlab ntsha hauv cov hlab ntsha. Tsis tas li ntawd, herba cistanche retinas muaj peev xwm rov tsim dua tom qab qee qhov kev raug mob thiab muab lub sijhawm tshwj xeeb los tshuaj xyuas cov txheej txheem rov tsim dua tshiab uas tuaj yeem pab txhawb rau kev txhim kho neuroprotective thiab kev kho dua tshiab hauv tib neeg. Muaj ntau qhov kev tshuaj xyuas ntxaws ntxaws uas tau tshaj tawm hauv 10 xyoo dhau los piav qhia txog cov cuab yeej siv dav dav (cov qauv hloov pauv, tshuaj tiv thaiv kab mob, ERGs, thiab kev coj tus cwj pwm pom) muaj rau kev tshawb fawb pom kev hauv zebrafish. Ntawm no, peb hais txog cov kev tshawb fawb tshiab uas tau ua haujlwm rau kev siv zebrafish los kawm thiab tsim cov tswv yim tiv thaiv kab mob thiab rov tsim dua tshiab thiab lub hom phiaj rau cov kab mob retinal. Peb tau sim sau cov ntaub ntawv tam sim no hais txog kev tiv thaiv kab mob ntawm lub qhov muag thiab rov tsim dua tshiab hauv zebrafish retinal raug mob paradigms.

Kev kho mob tseem ceeb ntawm Neurodegeneration hauv Retina Lub Zeem Muag poob hauv cov kab mob retina tshwm sim los ntawm ntau qhov sib txawv ntawm cov txheej txheem uas feem ntau ua rau cov cell tuag ntawm retinal neurons. Neurodegeneration yog li ib qho kev tshwm sim hauv qab tsis pom kev tsis pom kev poob hauv cov kab mob retinal, thiab cov ntaub ntawv pov thawj tseem ceeb rau nws lub luag haujlwm tseem ceeb hauv kev cuam tshuam ntawm retinal dystrophies thiab optic neuropathies. Neurodegeneration manifests clinically raws li morphological thiab functional hloov xws li thinning ntawm txheej txheej nuclear thiab degeneration ntawm lub ellipsoid cheeb tsam kuaj pom los ntawm optical coherence tomography (OCT), correlating rau qhov muag tsis pom kev pom tseeb ntawm qhov muag pom los yog electroretinogram (ERG) kuaj [6-8] . Qhov tseem ceeb ntawm kev kho mob ntawm retinal neurodegeneration, thiab tsis muaj kev xaiv kho mob, hais txog qhov tseem ceeb ntawm cov qauv tsiaj xws li herba cistanche, uas tso cai rau peb kom tshem tawm cov kab mob thiab nthuav tawm cov phiaj xwm kev kho mob.