Thanaka (H. Crenulata, N. Crenulata, L. Acidissima L.): Kev Tshawb Fawb Txog Kev Siv Tshuaj, Tshuaj lom neeg thiab kev siv tshuaj pleev ib ce Part 1

Abstract: Thanaka (H. crenulate, N. crenulate, L. acidissima L.) yog ib tsob ntoo zoo nkauj nyob rau sab hnub tuaj Asia siv los ntawm cov neeg Myanmar los tsim lawv lub ntsej muag tshwj xeeb uas yog siv rau kev tiv thaiv hnub ci thiab kev tu tawv nqaij txhua hnub. Ntxiv mus, nws yog siv raws li ib txwm tshuaj los kho ntau yam kab mob vim nws kuj yuav siv tau raws li ib tug tshuaj tua kab. Hauv qhov kev tshuaj xyuas zoo no, cov khoom siv tshuaj lom neeg thiab tshuaj lom neeg ntawm Thanaka tau sau tseg los ntawm 18 cov khoom tau los ntawm Scopus database. Ntau yam extracts ntawm Thanaka muaj ib tug tseem ceeb ntawm bioactive tebchaw uas muaj xws li antioxidant, anti-aging, anti-inflammatory, anti-melanogenic, thiab anti-microbial zog. Qhov tseem ceeb tshaj, Thanaka nthuav tawm qis cytotoxicity rau tib neeg cov kab ntawm tes. Kev siv cov khoom siv cog ntoo nrog ntau yam kev ua haujlwm lom neeg muaj txiaj ntsig tau feem ntau hloov cov khoom siv dag zog rau kev noj qab haus huv thiab ib puag ncig vim li cas cov khoom cog ntoo muaj qhov zoo xws li antioxidant, thiab cov kab mob tua kab mob thaum muab cov khoom noj tseem ceeb rau daim tawv nqaij. Qhov kev tshuaj xyuas no yog siv rau kev tshawb fawb, kev tsim kho, thiab kev lag luam ntawm Thanaka cov khoom tu tawv nqaij, tshwj xeeb, tshuaj pleev thaiv hnub. Cov tshuaj pleev thaiv hnub ntuj tau nyiam cov kev txaus siab loj heev uas yog lub peev xwm hloov pauv rau cov khoom tiv thaiv hnub ci uas siv cov tshuaj hluavtaws xws li oxybenzone uas yuav ua rau muaj teeb meem kev noj qab haus huv thiab kev puas tsuaj rau ib puag ncig.

Glycoside ntawm cistanche tuaj yeem ua rau muaj kev ua haujlwm ntawm SOD hauv plawv thiab daim siab cov ntaub so ntswg, thiab txo cov ntsiab lus ntawm lipofuscin thiab MDA hauv txhua cov ntaub so ntswg, tshem tawm ntau yam reactive oxygen radicals (OH-, H₂O₂, thiab lwm yam) thiab tiv thaiv DNA puas. los ntawm OH-radicals. Cistanche phenylethanoid glycosides muaj peev xwm tshem tawm cov dawb radicals, muaj peev xwm txo tau ntau dua li cov vitamin C, txhim kho cov haujlwm ntawm SOD hauv cov phev ncua, txo cov ntsiab lus ntawm MDA, thiab muaj qee yam kev tiv thaiv ntawm cov phev ua haujlwm. Cistanche polysaccharides tuaj yeem txhim kho kev ua haujlwm ntawm SOD thiab GSH-Px hauv erythrocytes thiab ntsws cov ntaub so ntswg ntawm cov nas senescent sim los ntawm D-galactose, nrog rau txo cov ntsiab lus ntawm MDA thiab collagen hauv lub ntsws thiab ntshav, thiab nce cov ntsiab lus ntawm elastin, muaj Cov nyhuv scavenging zoo ntawm DPPH, ncua lub sijhawm ntawm hypoxia hauv cov nas senescent, txhim kho cov haujlwm ntawm SOD hauv cov ntshav, thiab ncua lub physiological degeneration ntawm lub ntsws hauv kev sim cov nas nrog cellular morphological degeneration, kev sim tau pom tias Cistanche muaj peev xwm antioxidant zoo. thiab muaj peev xwm los ua ib qho tshuaj tiv thaiv thiab kho cov kab mob ntawm daim tawv nqaij laus. Nyob rau tib lub sijhawm, echinacoside hauv Cistanche muaj lub peev xwm tseem ceeb txhawm rau txhawm rau DPPH dawb radicals thiab muaj peev xwm tshem tawm cov pa oxygen reactive thiab tiv thaiv dawb radical-induced collagen degradation, thiab kuj muaj kev kho zoo ntawm thymine dawb radical anion puas.

Nyem rau qhov Kuv Yuav Yuav Cistanche

【Yog xav paub ntxiv:george.deng@wecistanche.com / WhatApp:86 13632399501 】

Ntsiab lus: khoom ntuj; ntuj tshuaj pleev thaiv hnub; ntsuab tshuaj pleev thaiv hnub; thaiv hnub ci; Hesperethusa crenulata; Nroj tsuag crenulata; Limonia acidissima L.

1. Taw qhia

Thanaka yog ib tsob ntoo uas tuaj yeem pom nyob ib puag ncig Asia. Cov npe tshawb fawb ntawm Thanaka suav nrog Hesperethusa crenulata (syn. Naringi crenulata) thiab Limonia acidissima L. Nws yog nyob rau tebchaws Myanmar, Is Nrias teb, Malaysia, Sri Lanka, Java, thiab Pakistan. Cov npe muaj xws li Thanaka rau Burmese thiab Belinggai hauv Malaysia. Tus ntoo Thanaka tau piav qhia thawj zaug los ntawm Talbot (1909) tias "ib tsob ntoo spinous, glabrous, me me" nrog cov pos ncaj, cov nplooj nplooj du, nrog 5-7 nplooj ntawv qhov twg ntug ntawm nplooj yog crenulate (minutely scalloped). Cov nplooj ntawv kuj tau piav qhia tias tsis muaj ntxhiab tsw thaum crushed. Cov txiv hmab txiv ntoo yog oblong, nrog dub, du textured rind, nrog liab / purplish-tinged nqaij. Thanaka yog tsob ntoo me me uas tuaj yeem loj hlob mus rau qhov siab ntawm 10 m, feem ntau loj hlob ntawm toj qhuav lossis hauv hav zoov qhuav. Lub qia yog lub teeb daj, nrog lub yellowish-grey, du thiab corky bark.

tsob ntoo Thanaka yog qhov tshwj xeeb rau cov neeg ntawm Myanmar qhov chaw daj hmoov av los ntawm cov ntoo tawv ntoo tau siv los ua cov khoom siv tawv nqaij thiab tshuaj pleev ib ce rau ntau tshaj 2000 xyoo. Cov ntawv pov thawj ntxov tshaj plaws ntawm kev siv Thanaka hauv Myanmar tuaj yeem pom nyob rau hauv 14-xyoo pua paj huam sau los ntawm King Razadarit tus khub thiab nyob rau xyoo pua 15th cov ntaub ntawv ntawm Shin Manaratthasara, ib tug kws sau paj huam Burmese. Cov ntaub ntawv pov thawj ntawm cov kayak tus pin (cov pob zeb puag ncig) tau pom tom qab av qeeg hauv xyoo 1930 hauv cov ruins ntawm Shwemawdaw Pagoda. Kyauk pin (round pob zeb slab) yog ib txwm siv los grind Thanaka bark hmoov thiab nws tau hais tias yog tus ntxhais ntawm King Bayinnaug uas kav nyob rau hauv lub xyoo pua 15th. Lub caij no, qee leej ntseeg tias keeb kwm ntawm Thanaka tuaj yeem rov qab los ntau dua 2000 xyoo dhau los thaum tus poj huab tais legendary ntawm Peikthano, poj huab tais Phantwar hlub Thanaka. Peikthano yog lub nroog Pyu thaum ub thiab raws li keeb kwm, cov neeg Pyu tau sib yuav nrog cov neeg Sino-Tibetan tsiv teb tsaws chaw thiab tom qab ntawd los ua ib feem ntawm haiv neeg Burman [1]. Cov lus dab neeg ntawm poj huab tais Phantwar yeej ib txwm nyiam cov menyuam yaus zaj dab neeg pw hauv Myanmar.

Hauv tebchaws Myanmar, kev siv Thanaka cov hmoov nplej yog ib feem ntawm lawv cov kab lis kev cai tshwj xeeb thiab cov neeg txaus siab hnav Thanaka muab tshuaj txhuam los ntawm kev sib xyaw Thanaka hmoov nrog dej. Cov neeg Burmese yuav zom cov tawv ntoo los ntawm kev siv tus pin kayak nrog dej los ua ib qho muab tshuaj txhuam uas ua rau lub siab txias thiab ib qho tshuaj tsw qab zoo li sandalwood. Raws li cov lus piv txwv qub Asian hais tias: "Cov poj niam zoo nkauj tshaj plaws hauv ntiaj teb muaj lub ntsej muag Thaib, Khab qhov muag, thiab tawv nqaij Burmese". Cov neeg Burmese tau paub txog lawv cov tawv nqaij zoo nkauj thiab cov neeg ntseeg tias nws yog vim muaj txiaj ntsig ntawm kev hnav Thanaka muab tshuaj txhuam raws li cov tshuaj pleev ib ce, uas xav tias yuav tiv thaiv pob txuv, smoothen daim tawv nqaij thiab muab kev tiv thaiv tshav ntuj. Tsis tas li ntawd, Thanaka muab tshuaj txhuam kuj tau siv los ua tshuaj yoov tshaj cum. Tsis tas li ntawd, rau kev kho mob ntawm daim tawv nqaij, cov poj niam Burmese kuj hnav Thanaka muab tshuaj pleev los ntawm kev kos duab paj raws li cov tshuaj txhuam yuav qhuav thiab nyob twj ywm raws li cov khoom daj daj tom qab cov kua nkag mus rau hauv daim tawv nqaij (Daim duab 1).

Ntau yam kev tshawb fawb tshuaj thiab tshuaj lom neeg tau ua tiav ntawm cov tawv ntoo, nplooj, txiv hmab txiv ntoo, thiab cov noob ntawm Thanaka txij xyoo 1971 txog rau lub sijhawm tam sim no. Nayar, Sutar, thiab Bhan (1971) thiab Nayar thiab Bhan (1972) tau txheeb xyuas cov alkaloid 4-methoxy-1-methyl-2- quinolone (I), ob coumarins suberin thiab parmesan los ntawm cov roj rho tawm ntawm H. crenulata [2,3]. Meanwhile, Joo et al. (2004) kuj pom parmesan hauv methanol / chloroform (1: 1) extract ntawm Thanaka uas muaj UV-absorbing chromophores uas tuaj yeem nqus tau ntau yam ntawm UV-A hluav taws xob pom nyob rau hauv cov qauv tshuaj ntawm parmesan [4]. Kim et al. (2008) pom 3 tyramine derivatives, acidissimina A, acidissimina B, thiab acidissimina B epoxide, thiab 2 phenolic compounds, oxirane-(3,{19}}dimethoxy-4-}hydroxy-phenyl)-methanol thiab oxirane-( 3,4,5-tri methoxy-phenyl)-methanol hauv ethyl acetate extract ntawm L. acidissima [5].

Raws li cov kev tshawb fawb yav dhau los tau hais, cov ntsiab lus polyphenol feem ntau pom muaj nyob hauv ntau yam Thanaka extracts. Polyphenol yog ib chav kawm ntawm cov nroj tsuag uas tsis yog-volatile secondary metabolite siv thoob plaws xyoo rau lawv cov txiaj ntsig kev noj qab haus huv uas, nyob ntawm lawv cov qauv tshuaj, tuaj yeem muab cov tshuaj tua kab mob antioxidant, tiv thaiv kab mob, thiab tshuaj tiv thaiv kab mob uas tuaj yeem pab tiv thaiv kab mob. . Ntawm cov sub-chav kawm ntawm polyphenols, coumarin pom muaj nyob rau hauv Thanaka extracts. Coumarin, los yog 2H-1-benzopyran-2-ib, yog ib feem ntawm cov chav kawm loj ntawm cov tshuaj phenolic ua los ntawm fused -pyrone rings thiab benzene [6]. Tsawg kawg yog 1300 txawv coumarins tau txheeb xyuas. Cov coumarins ntuj no tuaj yeem muab faib ua rau hom, feem ntau yooj yim coumarins, furanocoumarins, dihydrofuranocoumarins, pyranocoumarins, phenylcoumarins thiab bicoumarins [7]. Coumarins yog tus cwj pwm los ntawm UV-lub teeb nqus, uas ua rau muaj cov yam ntxwv xiav fluorescent uas tseem muaj cov duab zoo nkauj, hloov tau yooj yim los ntawm lub teeb ntuj [7,8]. Coumarins kuj tau sau tseg rau ntau yam tshuaj ua haujlwm xws li tshuaj tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, hypotensive, thiab tiv thaiv kab mob [7]. Yog li, coumarins yog siv nyob rau hauv ntau daim ntawv thov tshuaj. Ntxiv mus, coumarin muaj cov ntxhiab tsw qab uas zoo ib yam li cov nyom nyom tshiab, uas ua rau nws siv hauv cov tshuaj tsw qab txij li xyoo 1882 [7]. Coumarins kuj tseem siv rau hauv cov qauv ntawm cov khoom tu tawv nqaij xws li cov tshuaj pleev tom qab, cov khoom ntxuav, moisturizers, thiab tshuaj pleev thaiv hnub.

Hauv kev tshuaj xyuas no, cov khoom siv tshuaj lom neeg thiab tshuaj lom neeg ntawm Thanaka thiab nws cov ntawv thov tshuaj pleev ib ce tau sau tseg. Kev siv cov khoom siv cog qoob loo nrog ntau yam kev ua ub no muaj txiaj ntsig zoo yog tam sim no ib qho kev hloov pauv cov khoom siv dag zog rau kev tswj hwm kev noj qab haus huv thiab ib puag ncig teeb meem vim tias cov khoom cog ntoo muaj qhov zoo xws li antioxidant, thiab cov kab mob tua kab mob thiab muab cov khoom noj tseem ceeb rau daim tawv nqaij. Qhov kev tshuaj xyuas no yuav ua raws li kev siv rau kev tsim cov khoom tu tawv nqaij uas muaj Thanaka, tshwj xeeb, tshuaj pleev thaiv hnub. Cov tshuaj pleev thaiv hnub ntuj tau nyiam cov kev txaus siab loj heev raws li kev hloov cov khoom siv tiv thaiv lub hnub ua los ntawm cov khoom siv hluavtaws xws li oxybenzone uas yuav tsis tsuas yog ua rau muaj teeb meem kev noj qab haus huv tab sis kuj ua rau ib puag ncig zoo xws li dej paug thiab coral reef puas tsuaj.

2. Cov txheej txheem

Qhov kev tshuaj xyuas qhov systematic no tau ua raws li Cov Lus Qhia Tshaj Lij Tshaj Lij rau Kev Ntsuam Xyuas Txheej Txheem thiab Meta-Analyses (PRISMA) tus qauv [9]. Cov txheej txheem tau pab hauv kev xaiv cov ntaub ntawv ntsig txog thiab tsim nyog thiab ua rau muaj kev ntsuam xyuas thiab kev soj ntsuam ntawm qhov zoo thiab ua tib zoo saib xyuas.

Kev xa khoom ntawm cov khoom tau ua los ntawm Scopus database thaum Lub Rau Hli 2020. Thawj theem ntawm cov txheej txheem kev tshuaj xyuas muaj xws li kev txheeb xyuas cov ntsiab lus, tom qab ntawd los ntawm kev tshawb nrhiav cov ntsiab lus ntsig txog raws li encyclopedias thiab kev tshawb fawb yav dhau los. Nyob rau hauv cov ntaub ntawv no, cov ntsiab lus siv rau qhov kev tshuaj xyuas no yog ua raws li cov npe thiab kev tshawb fawb ntawm cov nroj tsuag nyiam los ua cov kev tshuaj xyuas kom ntxaws txog feem ntau ntawm cov nroj tsuag no, siv txoj hlua tshawb nrhiav raws li qhia hauv Table 1. Cov txiaj ntsig tam sim no tau ua tiav tiav. tag nrho ntawm 74 cov ntaub ntawv los ntawm Scopus database.

Kev tshuaj xyuas cov ntaub ntawv tau ua los xaiv cov ntaub ntawv tsim nyog. Nyob rau hauv cov ntaub ntawv no, tsis muaj ib tug duplicate tshwm sim li no cov ntaub ntawv 74 tau soj ntsuam ntxiv raws li ob peb inclusion thiab exclusion qauv. Thawj qhov kev ntsuas yog hom kab lus uas tsom mus rau thawj qhov kev tshawb fawb cov khoom. Yog li ntawd, cov ntawv tshaj tawm nyob rau hauv daim ntawv tshuaj xyuas, erratum, thiab rooj sib tham rooj plaub raug tshem tawm thiab, nyob rau hauv cov ntaub ntawv no, tag nrho ntawm tsib kab lus raug tshem tawm. Nws yog ib qho tsim nyog hais tias qhov kev tshuaj xyuas zoo tsuas yog tsom rau cov ntawv luam tawm ua lus Askiv, thaum tsis muaj qhov txwv tsis pub muab tso rau hauv ncua sij hawm vim muaj ob peb cov ntawv luam tawm. Qhov tseem ceeb tshaj plaws, cov khoom uas muaj cov ntawv nyeem puv tau raug xaiv. Cov khoom tau muab los ntawm Scopus tshawb nrhiav tau rub tawm ua cov ntawv sau tag nrho los ntawm kev tshawb fawb xyaw xws li Lancaster University OneSearch, Google Scholar, Elsevier, thiab ResearchGate. Zuag qhia tag nrho, tag nrho ntawm 50 kab lus raug xaiv rau cov txheej txheem tshuaj xyuas kev tsim nyog.

Rau kev ntsuam xyuas kev tsim nyog, lub npe, kev paub daws teeb meem, thiab cov ntsiab lus tseem ceeb ntawm tag nrho 50 kab lus tau raug tshuaj xyuas kom meej kom ntseeg tau tias cov ntaub ntawv tseem ceeb thiab txaus haum rau lub hom phiaj ntawm kev tshuaj xyuas. Li no, 32 kab lus raug tshem tawm. Tawm ntawm 32 kab lus uas raug tshem tawm, 14 kab lus tsis muaj feem cuam tshuam rau lub ntsiab lus hauv phau ntawv no thiab 13 kab lus muaj cov ntaub ntawv tsis txaus ntawm Thanaka. Thaum kawg, qhov seem 18 kab lus tau raug xaiv rau cov khoom tsim tau zoo raws li pom hauv daim duab 2. Cov ntaub ntawv teev nyob rau hauv Table 4 tau txais los ntawm Google tshawb fawb xyaw thiab cov vev xaib ntawm cov tuam txhab uas tsim cov khoom Thanaka nyob rau sab hnub tuaj Asia.

3. Chemical Constituents thiab Phytochemical Screening of Thanaka

Table 2 qhia txog cov tshuaj lom neeg thiab tshuaj phytochemical tsom xam ntawm Thanaka. Xyoo 1971, Nayar et al. pom tias alkaloid, 4-methoxy-1-methyl-2- quinolone, los ntawm Thanaka qia bark petroleum extract, tuaj yeem ntxuav los ntawm chromatography ntawm nruab nrab alumina thiab crystallized rau cov qauv molecular txheeb xyuas siv nuclear magnetic resonance (NMR) [2]. Tom qab xyoo 1972, Nayar thiab Bhan siv tib txoj kev li Nayar li al. 1971 thiab txheeb xyuas sitosterol hauv cov roj av feem, suberin, thiab 7- methoxy-6-(2,{11}}epoxy-6-}methylbutyl) coumarin los ntawm petro-benzene (19:1) feem , as well as 4-methoxy-1-methyl{18}}quinolone, parmesan thiab suberenol los ntawm petrol-benzene (9:1) feem [3]. Niu et al. (2001) muab rho tawm Thanaka qia tawv ntoo hmoov siv 70 feem pua ​​​​acetone, crude resuspended hauv dej, thiab rov muab rho tawm nrog ethyl acetate, ua raws li kab chromatography tshaj silica gel los ua ib feem ntawm chloroform, chloroform acetate (9: 1 thiab 4: 1) thiab acetone. Tom qab ntawd, crystalline los ntawm cov eluted fractions tau tshwm sim los ntawm optical rotation, IR spectra, UV spectra, huab hwm coj spectrometry (MS), thiab NMR, los txiav txim 21 bioactive compounds nyob rau hauv Thanaka qia bark: alkaloids (crenulate, n-benzoyl tyramine methyl ether, tembamid). , 4-Methoxy-6-hydroxy-1-methyl-2-quinolone), flavanones (20,40,5,7-Tetrahydroxyflavanone, 3,40,5,{{ 42}}Tetrahydroxyflavanone), cov tshuaj tsw qab (syringaldehyde, 1,3,5-trimethoxybenzene), coumarins (7-hydroxycoumarin, angustifolin, impaneling, moellendorffilin), triterpenoid (lupeol), tetranortrimonininoids deacetylnomilinate), steroids (stigmast-4-en-6 -ol-3-ib, schleicheol 2, 3 -hydroxy-5 ,8 -epidioxyergosta{{54} }, 22-diene) thiab lignans (syringaresinol, lyoniresinol) [10]. Xyoo 2004, Joo et al. 2004 muab rho tawm Thanaka tawv tawv siv methanol thiab chloroform (1: 1, v / v) hnyav, purified los ntawm silica gel chromatography, eluted nrog chloroform ua raws li nyias txheej chromatography (TLC) nrog 40: 1 (v / v) ntawm chloroform thiab methanol thiab ntxiv purified nrog silica gel chromatography [4]. Qhov thib ob TLC tau ua tiav kom tau txais cov feem nrog cov chaw muaj zog tshaj plaws fluorescence. Cov feem xaiv tau raug ntxuav ntxiv siv cov kua chromatography siab (HPLC) kom tau txais qhov kawg qhuav crystallized active compound rau huab hwm coj spectrometry (MS) tsom xam. Joo et al. (2004) tus yam ntxwv ntawm cov khoom xyaw nquag ua parmesan thiab pom tias nws cov qauv muaj peev xwm nqus tau ntau yam ntawm UV-A hluav taws xob [4]. Kim et al. (2008) tau rov ua kem chromatography ntawm ethyl acetate extracts ntawm Thanaka bark thiab pom 3 tyramine derivatives (acidissimina A, acidissimina B, thiab acidissimina B epoxide) thiab ob phenolic tebchaw (oxirane-(3, 5-dimethoxy{{74). }}hydroxy-phenyl)-methanol thiab oxirane-(3,4,5- tri methoxy-phenyl)-methanol) [5]. Sarada et al. (2011) tau txheeb xyuas 20 bioactive compounds (teev nyob rau hauv Table 2) pom nyob rau hauv Thanaka qia bark ethanol extract, lub caij no, 16 bioactive compounds (teev nyob rau hauv Table 2) nyob rau hauv Thanaka nplooj ethanol extract los ntawm Gas chromatography Mass spectrometry (GC-MS), nrog 5 Cov tshuaj sib xyaw ua ke suav nrog 3,5-dimethyl-Octane, 1,1,3-tri ethoxy-Propane, 3-ethyl-5-(2-ethyl butyl)- Octadecane, 9-hexyl-Heptadecane, thiab 1,3,5-trimethyl-2-octadecyl-cyclohexane) [11]. Sampathkumar thiab Ramakrishnan (2012) tau txheeb xyuas 27 lub tebchaw (teev nyob rau hauv Table 2) los ntawm GC-MS los ntawm Thanaka nplooj ethanol extract npaj los ntawm kub extraction txoj kev siv Soxhlet apparatus [12].

Qee cov kws tshawb fawb tau ua phytochemical tsom xam ntawm Thanaka extracts ua ntej loj spectrometry tsom xam los yog chromatography profiling. Sampathkumar thiab Ramakrishnan (2012b) ua phytochemical tsom xam ntawm qia, tawv, thiab nplooj ntawm Thanaka muab rho tawm nrog ethanol thiab qhia tias ethanolic nplooj extract ua rau muaj proteins, lipids, phenols, tannins, flavonoids, saponins, thiab quinones, thaum lub ethanolic qia extract muaj cov proteins, lipids, phenols, carbohydrate, txo cov suab thaj, tannin, flavonoid, saponin, thiab alkaloids; cov ethanolic bark extract kuj tau tshaj tawm tias muaj yuav luag tib cov ntsiab lus raws li cov qia extract tsuas yog tsis muaj alkaloid txiav txim siab thaum triterpenoid thiab quinone nyob hauv cov tawv ntoo extract [13]. Sampathkumar thiab Ramakrishnan (2012) tom qab ntawd profiled cov extracts ntawm qia, tawv, thiab nplooj siv high-performance nyias-txheej chromatography (HPTLC) thiab pom 10 peaks nrog Rf qhov tseem ceeb nyob rau hauv qhov ntau ntawm 0.08 rau 0.65 hauv qia ethanol extract; 8 peaks nrog Rf qhov tseem ceeb hauv thaj tsam ntawm 0.07 txog 0.63 hauv bark ethanol extract; thiab 8 peaks nrog Rf qhov tseem ceeb hauv thaj tsam ntawm 0.09 txog 0.49 hauv nplooj ethanol extract. Pratheeba et al. (2019) tau tshaj tawm tias phytochemical Cheebtsam ntawm Thanaka nplooj muab rho tawm nrog cov kuab tshuaj sib txawv uas txawv ntawm hexane (tsis-polar) extract muaj alkaloids, quinones, thiab carbohydrates thaum ethyl acetate (me ntsis polar) rho tawm tsuas muaj saponins thiab carbohydrates. Thaum methanol (polar) thiab acetone (polar) muaj cov khoom zoo sib xws (phenols, alkaloids, saponins, tannins, thiab carbohydrates) methanol extract muaj cov khoom ntxiv ntawm cov protein thiab flavonoids. Tom qab ntawd lawv tau ua GC-MS tsom xam ntawm Thanaka txiv hmab txiv ntoo acetone extract thiab txheeb xyuas 8 lub tebchaw raws li teev nyob rau hauv Table 2 [14]. Lub caij no, Vasant thiab Narasimhacharya (2013) tau ua ib qho kev soj ntsuam phytochemical ntawm roj av ether extracts ntawm Thanaka txiv hmab txiv ntoo thiab qhia fibers (47 g / kg), phytosterols (38.7 g / kg), polyphenols (67.4 g / kg), flavonoids (0.6 g / kg), saponins (0.18 g / kg) thiab ascorbic acid (0.54 g / kg), txawm li cas los xij, lawv tsis tau ua ib qho kev soj ntsuam MS ntxiv lossis kev txheeb xyuas raws li lawv lub hom phiaj tseem ceeb yog los saib xyuas cov txiaj ntsig ntawm Thanaka txiv hmab txiv ntoo hauv fluoride-induced hyperglycemia. thiab hyperlipidemia [15]. Coincidentally, Pandavadra thiab Chanda (2014) kuj tau ua tsuas yog phytochemical tsom xam yam tsis tau ntxiv MS tsom xam lossis profileing ntawm cov hmoov nplej ntawm Thanaka qia tawv thiab nplooj, qhia tias Thanaka crude qia bark hmoov muaj alkaloids, flavonoids, plawv glycosides, triterpenes, thiab steroids. thaum Thanaka nplooj hmoov hmoov muaj alkaloids, flavonoids, tannins, plawv glycosides, triterpenes thiab steroids [16].

Ntawm tag nrho cov txiaj ntsig chromatography, ib qho kev sib xyaw ua ke (Caryophyllene) tau pom nyob rau hauv cov kev tshawb fawb ua los ntawm Sarada li al. (2011) thiab Pratheeba et al. (2019). Txawm li cas los xij, kev ua haujlwm lom neeg ntawm cov khoom sib txuas hauv kab lus 2 tsis tau tham thiab tshawb xyuas los ntawm cov kws sau ntawv.

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