Txoj Kev Kawm Txog Kev Ntsuas Tus Qauv Ntawm Lub raum Deficiency Syndrome hauv Lub Sijhawm Rov Qab Los Ntawm Ischemic Stroke Raws Li Ntau Qhov Kev Nkag Mus Los

Abstract:

Lub Hom Phiaj Tsim kom muaj tus qauv kuaj mob ntawmlub raum tsis muaj peev xwmsyndrome nyob rau hauv lub sij hawm rov qab ntawm ischemic stroke raws li ntau yam Logistic regression txoj kev.

Cov txheej txheem Los ntawm cov yav tom ntej, ntau lub chaw, thiab dynamically sau plaub-diagnosis cov ntaub ntawv soj ntsuam, 181 convalescent cov neeg mob nrog ischemic stroke uas tau raws li cov kev xam thiab cais cais tau suav nrog nyob rau hauv 15 sub-centers, thiab tag nrho ntawm 970 cov ntaub ntawv ua tiav cov ntaub ntawv yog tau. Tus qauv kuaj mob ntawmlub raum deficiency syndrometau tsim los ntawm kev siv multivariate Logistic regression, thiab qhov ua tau zoo tau txiav txim los ntawm ROC nkhaus. Cov txiaj ntsig tau tshuaj xyuas 12 yam xws li pob txha pob txha, mob nraub qaum, tso zis ntau zaus, tsis nco qab, tsis muaj zog pulse, kub flashes, lub hauv caug mos, tsib chim kub taub hau, tsis muaj npe, lub duav txias, tso zis ntau thiab ntev, thiab sib sib zog nqus thiab thready mem tes, uas yog tus yuam sij. Cov laj thawj rau ischemic stroke rov qab.Lub raum tsis muaj peev xwm

Cov kev sib raug zoo ntawm cov pov thawj tau tsim, thiab tus qauv kuaj pom tau tsim: P{{0}}/[1 ntxiv rau Exp (11.223-2.002 × zygomatic liab { {5}}. flashes - 1.297 × mos lub hauv caug - 1.181 × tsib chim kub cev - 1.028 × listlessness - 0.742 × lub duav txias - 0.722 × meej thiab cov zis ntev - 0.594 × sib sib zog nqus thiab thready mem tes)], thaj tsam hauv qab ROC nkhaus ntawm tus qauv kev twv ua haujlwm yog 0.946, thiab Youden Performance index yog 0.766, rhiab heev ntawm tus qauv kuaj mob yog 90.5 feem pua, Qhov tshwj xeeb yog 85.4 feem pua ​​​​, thiab kev kuaj mob sib xws ntawm tib tus qauv yog 84.1 feem pua.

Nyem qhov no kom paub ntau ntxiv txog Yuav Ua Li Cas Cistanche Treatlub raum tsis muaj peev xwm

NUG INFO NTAWM: wallence.suen@wecistanche.com 0015292862950

Xaus Los ntawm multivariate Logistic regression tsom xam, tus qauv kuaj mob ntawmlub raum tsis muaj peev xwmSyndrome nyob rau lub sijhawm convalescent ntawm ischemic stroke raws li cov ntaub ntawv ntawm plaub qhov kev kuaj mob tau tsim los muab cov cuab yeej siv rau kev txheeb xyuas cov mob raum tsis txaus nyob rau lub sijhawm convalescent ntawm ischemic stroke.

Ntsiab lus: rov qab lub sij hawm ntawm ischemic stroke;Syndrome ntawm lub raum tsis muaj peev xwm; ntau logistic regression; ROC nkhaus; kuaj ntsuas ntsuas

Mob stroketau dhau los ua tus thib ib ua rau muaj kev tuag thiab kev tsis taus nyob rau hauv Suav cov neeg laus [1-2], ntawm cov ischemic stroke suav txog li 60 feem pua ​​​​rau 80 feem pua ​​[3], nqa lub nra hnyav rau peb lub tebchaws. Txawm hais tias thrombolysis thiab lwm yam vascular recanalization tuaj yeem txhim kho kev ua haujlwm ntawm lub paj hlwb ntawm cov neeg mob hlab ntsha tawg, vim lub sijhawm nqaim ntawm lub qhov rais thiab tsis tshua muaj kev nkag tau yooj yim, cov neeg mob feem ntau tseem muaj qhov tsis zoo ntawm lub paj hlwb xws li limb dysfunction thiab aphasia tom qab nkag mus rau lub sijhawm rov qab los. Cov tsos mob [4]. Cov tshuaj suav ua lub luag haujlwm tseem ceeb hauv kev kuaj mob thiab kev kho mob ntawm ischemic stroke rov qab lub sijhawm [5]. Nrog rau kev kawm tob ntawm "lub hlwb-lub raum kev sib raug zoo" txoj kev xav, nws feem ntau ntseeg tias "kev puas tsuaj, lub hlwb tsis txaus, thiab lub hlwb tsis ua haujlwm" yog cov kab mob ntawm cov hlab ntsha tsis txaus tom qab mob stroke [6]. Cov txheej txheem kuaj mob yav dhau los rau ischemic stroke syndrome cov ntsiab lus ntawm "cua, hluav taws, phlegm, ntshav stasis, qi deficiency, thiab yin deficiency" tseem tsis muaj cov cuab yeej kuaj mob ntau rau cov mob ischemic stroke nrog raum tsis muaj peev xwm, uas cuam tshuam rau kev soj ntsuam kev ua tau zoo, thiab lwm yam. . ntsig txog kev tshawb fawb. Yog li ntawd, nws yog ib qho tsim nyog yuav tsum tsim kom muaj qhov ntsuas ntsuas ntsuas los ntawm kev ua ntau lub cheeb tsam, ntau lub chaw, thiab ntau lub sijhawm tshawb xyuas ntawm lub raum deficiency syndromes nyob rau lub sijhawm convalescent ntawm ischemic stroke, thiab tshuaj xyuas cov ntaub ntawv ntawm plaub cov ntaub ntawv kuaj mob. . Txoj kev tshawb no npaj los tshuaj xyuas plaub cov ntaub ntawv kuaj mob ntsig txog kev tsimlub raum deficiency syndromelos ntawm multivariate Logistic regression kev ntxub ntxaug, tsim cov qauv kuaj mob ntawm lub raum deficiency syndrome nyob rau lub sijhawm rov qab los ntawm ischemic stroke, thiab muab cov ntaub ntawv siv rau kev kuaj mob ntau.

1 Cov ntaub ntawv thiab cov txheej txheem

1.1 Cov ntaub ntawv dav dav

Txoj kev tshawb no yog ib tug yav tom ntej, multi-center, dynamic sau ntawm plaub yam ntaub ntawv ntsuam xyuas. Ua nyob rau hauv 15 sub-centers, suav nrog: Tsev Kho Mob Dongzhimen ntawm Beijing University of suav tshuaj, Lianyungang Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Linfen Central Tsev Kho Mob, Weifang Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Luohe Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Jincheng University Tsev Kho Mob, Fourth Affiliated Tsev Kho Mob ntawm Nanchang University, Rizhao City Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Plaub Lub Tsev Kho Mob ntawm Liaoning University of Traditional Chinese Medicine, Jiulongpo District Tsev Kho Mob ntawm Cov Tshuaj Suav Tshuaj ntawm Chongqing, Huaian Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Kunming Tsev Kho Mob ntawm Tsob Ntoo Suav Tshuaj, Koom Haum Tsev Kho Mob ntawm Jiujiang Medical College, Lub Tsev Kho Mob Thib Ob ntawm Luoyang City of Traditional Chinese Medicine, Tib Neeg Lub Tsev Kho Mob ntawm Ganzhou City. Cov neeg mob rov qab los ntawm ischemic stroke uas tau pom hauv lawv lub tsev kho mob lossis tsev kho mob raug xaiv.

Raws li kev suav ntawm 33 yam khoom koom nrog hauv "Cov Ntaub Ntawv Sau Daim Ntawv Qhia Txog Plaub Qhov Kev Ntsuas Ntawm Lub Raum Tsis Txaus Siab Hauv Lub Sijhawm Rov Qab Los ntawm Ischemic Stroke" [7], cov ntaub ntawv sau tseg yuav tsum tsis pub tsawg dua 660 tus neeg mob. Tag nrho ntawm 181 tus neeg mob convalescent nrog ischemic stroke uas ua tau raws li cov txheej txheem suav nrog thiab suav nrog, suav nrog 122 tus txiv neej thiab 59 tus poj niam; hnub nyoog 40-78 xyoo, nrog rau hnub nyoog nruab nrab ntawm (60.7 ± 8.29) xyoo; 111 tus neeg mob sab hauv thiab 111 tus neeg mob sab nraud.

70 rooj; tag nrho ntawm 970 kis ntawm kev sau cov ntaub ntawv tiav tau txais. Txoj kev tshawb no tau pom zoo los ntawm Pawg Saib Xyuas Kev Ncaj Ncees ntawm Tsev Kho Mob Dongzhimen, Beijing University of Traditional suav tshuaj (tus naj npawb pom zoo: DZMEC-JG-2017-79).

1.2 Cov txheej txheem kuaj mob

Western tshuaj diagnostic cov txheej txheem: Western tshuaj ntsuam xyuas cov txheej txheem rau ischemic stroke yog tsim nrog siv rau cov kev kuaj mob rau ischemic stroke nyob rau hauv "Cov lus qhia rau kev kuaj mob thiab kev kho mob ntawm tus mob Ischemic Stroke nyob rau hauv Tuam Tshoj 2018" [8]: ① mob tshwm sim; ② Focal neurological function Defects (tsis muaj zog los yog loog loog ntawm ib sab ntawm lub ntsej muag los yog ceg ceg, lus barrier, thiab lwm yam), ob peb yog cov kev puas hlwb tsis txaus; ③ Lub sijhawm ntawm cov tsos mob lossis cov cim qhia tsis txwv (thaum kev kuaj pom pom muaj lub luag haujlwm ischemic lesions), lossis kav ntev dua 24 teev (Thaum tsis muaj cov duab thaij duab lub luag haujlwm); ④ Tsis suav nrog cov kab mob vascular; ⑤ Brain CT lossis MRI kom tshem tawm cov ntshav hauv hlwb. Kev kuaj mob los ntawm theem: Lub sijhawm rov zoo yog 2 lub lis piam mus rau 6 lub hlis tom qab pib.

Cov txheej txheem kuaj mob rau TCM syndromes: Cov txheej txheem sib txawv ntawm lub raum tsis muaj peev xwm tau tsim nrog kev siv rau cov txheej txheem sib txawv ntawm cov mob raum.lub raum yin deficiencythiablub raum yang deficiencynyob rau hauv "Cov Cai Qhia Txog Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Cov Tshuaj Tshiab Suav" (Siv) [9]. Cov tsos mob tseem ceeb: mob los yog mob khaub thuas nyob rau hauv lub duav thiab lub hauv caug, listlessness los yog unresponsiveness los yog sluggish txav, tsis nco qab, urinary incontinence los yog nquag tso zis, nquag nocturia los yog ntshiab thiab ntev tso zis. Cov tsos mob thib ob: ua daus no thiab txias txias, tsib chim siab kub taub hau lossis kub hnyiab thiab hmo ntuj tawm hws, kiv taub hau lossis qhov muag tsis pom kev, plaub hau poob thiab hniav tshee, tinnitus thiab lag ntseg. Tus nplaig pulse: daj ntseg nplaig, nyias nyias plaub los yog me me los yog tsis muaj plaub, tsis muaj zog los yog sib sib zog nqus thready los yog qeeb mem tes. Nrog 1 cov tsos mob tseem ceeb lossis ntau dua 2 cov tsos mob thib ob, ua ke nrog tus nplaig thiab mem tes, cov tsos mob tuaj yeem sib txawv raws li cov tsos mob qub.

1.3 Cov txheej txheem suav nrog

① Cov neeg mob uas ua tau raws li kev kuaj mob ntawm ischemic stroke hauv Western tshuaj; ② Cov neeg mob uas ua tau raws li cov txheej txheem kuaj mob ntawm lub raum tsis muaj zog hauv lub sijhawm rov qab los ntawm ischemic stroke hauv cov tshuaj suav tshuaj; ③ Cov kab mob yog 2 mus rau 6 lub lis piam tom qab pib; ④ Hnub nyoog ntawm 40 thiab 80 xyoo; Kuaj thiab kos npe rau kev pom zoo.

1.4 Cov txheej txheem cais tawm

① Cov neeg mob cerebral infarction tshwm sim los ntawm cov qog, raug mob, kab mob ntshav, thiab lwm yam.; ② Cov neeg mob uas muaj kev puas siab puas ntsws hnyav; ③ Cov poj niam cev xeeb tub, lactating cov poj niam lossis cov uas muaj txoj kev npaj rau tsev neeg yav tom ntej; ④ Cov neeg mob uas muaj kev paub tsis meej, aphasia lossis tsis tuaj yeem piav qhia meej txog lawv tus kheej cov kab mob; ⑤ Cov neeg uas xav tias lossis muaj keeb kwm ntawm cawv lossis yeeb tshuaj, lossis tsis haum rau kev suav nrog hauv tus kws tshawb fawb qhov kev txiav txim.

1.5 Kev sau cov ntaub ntawv

Kev sau cov ntaub ntawv feem ntau suav nrog cov hauv qab no: ① Cov ntaub ntawv tseem ceeb ntawm cov neeg mob: lub npe, poj niam txiv neej, hnub nyoog, lub sijhawm pib, lub sijhawm rov qab los, keeb kwm ntawm tus kheej, keeb kwm yav dhau los, thiab lwm yam; ② Kev kuaj kab mob: Kev kuaj mob hauv Suav teb, kuaj tshuaj Western, thiab kev txiav txim siab ntawm kev suav nrog thiab cais tawm; ③ Sau cov ntaub ntawv qhia txog plaub yam kev kuaj mob: txais yuav "Ischemic Stroke Convalescence Stage Kidney Deficiency Syndrome Four Diagnosis Information Collection Form", suav nrog 33 yam khoom sib txawv hauv tag nrho; ④ Kev txiav txim siab rau lub raum deficiency syndrome; ⑤ Lwm cov ntaub ntawv.

Kev sau cov ntaub ntawv suav nrog cov ntsiab lus hauv qab no 6 lub sijhawm: 2 lub lis piam txij thaum pib, 4 lub lis piam txij thaum pib, 6 lub lis piam txij thaum pib, 8 lub lis piam txij thaum pib, 12 lub lis piam txij thaum pib, thiab 14 lub lis piam txij thaum pib. 4 cov ntaub ntawv sib sau ua ke ntawm plaub qhov kev kuaj mob thiab kev txiav txim siab ntawm lub raum deficiency syndromes ua rau tag nrho ntawm 970 tus neeg mob ntawm cov ntaub ntawv sau tag nrho.

1.6 Kev Tswj Xyuas Zoo

Nws yog qhov yuav tsum tau ua kom cov kws tshawb fawb ntawm txhua lub chaw yuav tsum siab dua qib ntawm cov laus tuaj koom TCM cov kws kho mob hauv Department of Encephalopathy. Ua ntej pib txoj kev tshawb no, cov kws kho mob koom nrog hauv kev kuaj mob ntawm TCM syndromes yuav tsum tau txais kev cob qhia zoo ib yam thiab cov kev ntsuas sib xws yuav tsum tau ua kom ntseeg tau tias kev kho mob ntawm ischemic stroke nrog raum tsis txaus nyob rau lub sijhawm rov qab los. Kev tshawb nrhiav tau ua tom qab kev soj ntsuam kev txiav txim siab ntawm cov tsos mob zoo ib yam (kev sib raug zoo> 85 feem pua); cov sub-centers tau saib xyuas thaum lub sijhawm tshawb fawb kom txo qis heterogeneity ntawm cov chaw. EDC system yog siv los sau ob npaug rau kev soj ntsuam cov txiaj ntsig kom ntseeg tau qhov tseeb thiab kev ntseeg siab ntawm cov ntaub ntawv.

1.7 Cov txheej txheem txheeb cais

SPSS 17.<0.05 was considered statistically significant. Taking whether the diagnosis of clinical syndrome is established or not as the dependent variable (1 = the syndrome of kidney deficiency is established, 0 = the syndrome of kidney deficiency is not established), and the variables with statistical significance in the χ2 test are introduced into the multivariate Logistic regression equation, and the forward step method is selected, and the maximum iteration is The number of times is 100, with P<0.05 as the detection level of the stepping variable, and P>0.10 raws li qib kev tshawb pom ntawm kev tshem tawm qhov sib txawv; thiab tus nqi kwv yees tus nqi ntawm kev ua haujlwm regression yog tsim nyob rau hauv SPSS, thiab tangent point ntawm tus qauv yog kwv yees thiab ntsuam xyuas los ntawm ROC nkhaus diagnostic kev ua tau zoo.

2 kev tshwm sim

2.1 Univariate tsom xam ntawm plaub qhov kev kuaj mob cov ntaub ntawv hais txog lub raum deficiency syndrome nyob rau hauv lub convalescent theem ntawm ischemic stroke

Kev tshuaj ntsuam xyuas tsis sib xws tau pom tias ntawm 33 yam ntawm lub raum tsis muaj peev xwm nyob rau lub sijhawm rov qab los ntawm ischemic stroke, chills, txias extremities, tsaus muag, ceg tawv, tsis muaj zog tawm hws, tsis muaj npe, qeeb zog, tinnitus, tsis nco qab, tsib chim siab kub taub hau, kub flashes, cov hws tawm hws, hmo ntuj tawm hws, mob nraub qaum, mob hauv caug, lub duav mos, lub hauv caug mos, lub duav txias, lub hauv caug txias, tso zis tsis txaus, tso zis luv, tso zis ntau zaus, tso zis ntau zaus thaum hmo ntuj, tso zis ntshiab thiab ntev, me ntsis lossis tsis muaj txheej, tus nplaig 28 Cov yam ntxwv xws li kev rog rog, tsis muaj zog pulse, thiab sib sib zog nqus thready mem tes tau cuam tshuam nrog kev tsim cov mob raum tsis muaj zog hauv lub sijhawm rov qab los ntawm ischemic stroke (P<0.05). See Table 1.

2.2 Multivariate logistic regression tsom xam ntawm plaub cov ntaub ntawv kuaj mob ntsig txog raum tsis muaj pov thawj thaum lub sij hawm ischemic stroke rov qab Lub 28 qhov sib txawv nrog P<0.05 in the univariate analysis were included in the multivariate logistic regression analysis, and the stepwise model was used. Results The results showed that after excluding the influence of confounding factors, zygomatic redness, lumbar soreness, frequent urination, amnesia, weak pulse, hot flashes, knee tenderness, five heart troubles, heat The 12 factors, including mental depression, lumbar coldness, clear and long urine, and sunken pulse, were correlated with the establishment of kidney deficiency evidence in the recovery period of ischemic stroke. (P<0.05). See Table 2.

2.3 Diagnostic modeling ntawm lub raum deficiency pov thawj nyob rau hauv lub rov qab lub sij hawm ntawm ischemic stroke

Raws li cov txiaj ntsig ntawm kev sib txawv ntawm cov logistic regression, tus qauv kuaj mob ntawm lub raum tsis txaus hauv ischemic stroke rov qab tau tsim: P=1/[1 ntxiv rau Exp(11.223-2.002 × liab pliv - 1 }. {15}}.297 × lub hauv caug tsis muaj zog - 1.181 × kub taub hau hauv tsib lub siab - 1.028 × kev nyuaj siab - 0.742 × lumbar coldness - 0.722 × tso zis ntshiab thiab ntev - 0.594 × sunken mem tes)], qhov twg txhua yam yog ib tug dichotomous variable (1=yog, 0=tsis), thiab tsim ib tug tus kheej kwv yees tus nqi sib txawv.

Tus kheej kwv yees tus nqi sib txawv tau tsim. ROC nkhaus tau tsim kho ntxiv los txiav txim siab qhov kev kuaj mob ntawm tus qauv los ntawm kev sib txuas cov txiaj ntsig ntawm cov kws tshaj lij. Raws li ROC nkhaus, tus nqi khi ntawm qhov siab tshaj plaws ntawm tus qauv Yuden Performance index ({{0}}}.766) yog 0001 3, thiab cheeb tsam hauv qab qhov nkhaus yog 0.946, p < 0.001, qhia tias tus qauv kev ua haujlwm kwv yees muaj txiaj ntsig zoo. Lub sijhawm no, qhov kev nkag siab ntawm tus qauv kuaj mob no yog 90.5 feem pua, thiab qhov tshwj xeeb yog 85.4 feem pua.

Ib yam li qhov kev pom zoo kuaj pom tseeb ntawm phau ntawv no yog 84.1 feem pua. Kev kwv yees ROC nkhaus ntawm tus qauv kuaj mob rau lub raum tsis muaj pov thawj hauv lub sijhawm rov qab los ntawm ischemic stroke tau qhia hauv daim duab 1.

3 Kev sib tham

Raws li lub hauv paus ntawm kev kuaj mob thiab kev kho mob hauv TCM, yuav ua li cas kom ua tiav cov pov thawj tseeb thiab zoo ib yam yog tus yuam sij rau kev soj ntsuam thiab kev tshawb fawb hauv TCM. Ischemic stroke, uas yog ib qho teeb meem loj rau kev noj qab haus huv, tau ntev tau ua kom pom tseeb ntawm TCM tus qauv kev ua haujlwm. Tom qab ua tiav ntawm lub teb chaws "8th Tsib-Year Plan" kev tshawb fawb thiab thev naus laus zis project ntawm kev kuaj mob stroke thiab luam tawm ntawm "Diagnostic Criteria for Ischemic Stroke" hauv 1994 [10], peb pab neeg tau tsim "Kev Ntsuas Kev Ntsuas rau Ischemic. Stroke" raws li cov ntaub ntawv ntawm 14,880 tus neeg mob thiab cov txiaj ntsig ntawm kev sau cov tsos mob, uas muaj 6 subscales cua, hluav taws kub, phlegm, stasis, qi deficiency thiab yin deficiency. Diagnostic Scale of Ischemic Stroke Symptom Elements [11] tau tsim los ntawm cov ntaub ntawv sau los ntawm 14,880 tus neeg mob thiab cov txiaj ntsig ntawm kev sau cov ntaub ntawv cov tsos mob.

Vim yog qhov nyuaj ntawm cov ntaub ntawv sib txawv, qhov ntsuas ntsuas rau ischemic stroke tau tsim los ntawm kev tshem tawm cov kab mob ntawm lub raum tsis txaus xws li yang deficiency thiab yin deficiency thiab hyperactivity raws li cov ntaub ntawv kho mob. Nrog rau kev kawm tob ntawm lub hlwb thiab lub raum txoj kev xav, cov kev kho rau lub raum tau maj mam hais txog kev tiv thaiv thiab txhim kho cov kab mob ischemic stroke, thiab kev soj ntsuam thiab kev tshawb fawb hauv paus ntawm cov pov thawj ntawm lub raum tsis txaus nyob rau lub sijhawm rov qab los. ntawm ischemic stroke tau nce ntxiv [12], uas kuj tau tsim qhov kev thov kom muaj nuj nqis ntawm cov tsos mob. Txhawm rau hais txog qhov xav tau no, txoj kev tshawb fawb tam sim no tau ua los ntawm kev txhim kho "Diagnostic Scale of Ischemic Stroke Evidence Elements", thiab ib qho kev kuaj mob kom muaj nuj nqis ntawm lub raum tsis txaus cov pov thawj hauv ischemic stroke rov qab los ntawm kev xaiv ntau yam Logistic regression algorithm. lim thiab xam lub zog ntawm plaub qhov kev kuaj mob cov ntaub ntawv cuam tshuam rau kev tsim cov pov thawj ntawm lub raum tsis txaus. Lub algorithm yog raws li qhov loj ntawm qhov sib xws ntawm cov qauv kuaj mob rau cov neeg mob uas muaj cov tsos mob tshwm sim thiab muaj feem xyuam rau cov ntaub ntawv uas qhov sib txawv ntawm qhov sib txawv yog dichotomous sib txawv [13-14].

Hauv txoj kev tshawb no, peb pib muab plaub yam kev kuaj mob ntsig txog lub raum tsis muaj pov thawj hauv ischemic stroke rov qab, suav nrog 12 yam khoom suav nrog zygomatic liab, mob lumbar, tso zis ntau zaus, amnesia, tsis muaj zog pulse, kub flashes, hauv caug tsis muaj zog, chim siab kub hauv tsib lub siab. , kev puas siab puas ntsws , lumbar txias , tso zis ntshiab thiab ntev , thiab cov mem tes sunken , thiab muab cov khoom siv sib xws, ntawm cov zygomatic liab, lumbar mob, nquag tso zis, thiab amnesia yog plaub yam tseem ceeb tshaj plaws. Lub raum yog lub cev ntawm dej thiab hluav taws, lub hauv paus ntawm yin thiab yang, tus tswv ntawm cov pob txha thiab cov pob txha, lub hlwb thiab ob lub plab, thiab nws cov peev yog lub duav. Yog hais tias lub raum tsis txaus yin thiab yang ntab saum toj, ces lub puab tsaig yog liab; yog tias lub raum tsis muaj qhov tseem ceeb thiab lub duav khoob, ces lub duav yog mob; yog tias lub raum tsis khov thiab tsis tuaj yeem ua dej, ces cov zis nquag; Yog tias lub raum tsis muaj zog thiab lub hlwb tsis ua haujlwm, lub hlwb tsis ua haujlwm, ces lub cim xeeb tsis nco qab. Plaub cov tsos mob no qhia txog cov yam ntxwv ntawm ntau yam ntawm lub raum tsis muaj peev xwm, xws li raum yin deficiency thiab yang hyperactivity, lub raum tsis muaj peev xwm, lub raum qi deficiency, thiab lub raum pob txha tsis muaj peev xwm, uas yog raws li kev hloov pauv ntawm pathogenesis ntawm ischemic stroke kab mob los ntawm raum tsis muaj peev xwm, suav nrog "yin tsis muaj peev xwm thiab cua sab hauv" thiab "cov ntsiab lus tsis txaus thiab cov pob txha puas tsuaj" [15]. Clinical manifestations [15]. Nws tau pom tias lub raum tsis txaus yog ib qho tseem ceeb ntawm cov tsos mob ntawm kev puas siab puas ntsws hauv lub sijhawm rov qab los ntawm ischemic stroke, thiab cov txheej txheem ntawm tonifying lub raum thiab pab cov pob txha tuaj yeem txhim kho cov neeg mob lub neej txhua hnub thiab kev txawj ntse, uas muaj txiaj ntsig zoo. lawv prognosis [16-17]. Yog li ntawd, nws yog ib qho tseem ceeb los tsim ib qho kev kuaj mob rau cov pov thawj ntawm lub raum tsis muaj peev xwm nyob rau hauv ischemic stroke rov qab, thiab txhim kho lub hom phiaj thiab qhov tseeb ntawm cov pov thawj-raws li kev kho mob los coj cov kev kho mob ntawm ischemic stroke rov qab cov neeg mob nyob rau hauv Suav tshuaj.

Nyob rau hauv txoj kev tshawb no, ib qho kev kuaj mob ntau yam muaj xws li 12 yooj yim-rau-sau thiab yooj yim-rau-paub soj ntsuam plaub cov ntaub ntawv kuaj mob tau tsim los ntawm multivariate logistic regression qauv thiab ROC nkhaus kev tshuaj ntsuam ntawm ciam teb qhov tseem ceeb.

Cov qauv tsim nyob rau hauv txoj kev tshawb no muaj kev kuaj mob zoo thiab tuaj yeem muab cov cuab yeej siv rau kev txheeb xyuas cov pov thawj ntawm lub raum tsis txaus nyob rau lub sijhawm rov qab los ntawm ischemic stroke.