3.8. Molecular Interaction Hloov tom qab Lub Sij Hawm Ntev

Raws li kev tshawb fawb cuam tshuam,cistancheyog ib hom tshuaj ntsuab uas hu ua "cov tshuaj ntsuab miracle uas ua rau lub neej ntev". Nws lub ntsiab tivthaiv yogcistanoside, uas muaj ntau yam teebmeem xws liantioxidant, anti-inflammatory, thiabkev tiv thaiv kev ua haujlwm txhawb nqa. Lub mechanism ntawm cistanche thiabtawv nqaij dawbnyob rau hauv cov nyhuv antioxidant ntawm cistancheglycosides. Melanin nyob rau hauv tib neeg daim tawv nqaij yog tsim los ntawm oxidation ntawm tyrosine catalyzed los ntawmtyrosinase, thiab cov tshuaj tiv thaiv oxidation yuav tsum muaj kev koom tes ntawm oxygen, yog li cov pa oxygen dawb radicals hauv lub cev dhau los ua qhov tseem ceeb.cuam ​​tshuam rau melanin ntau lawm.Cistanche muaj cistanoside, uas yog ib qho antioxidant thiab tuaj yeem txo qhov tsim ntawm cov dawb radicals hauv lub cev, yog liinhibiting melanin ntau lawm.

Nyem rau ntawm Cistanche Tubulosa Ntxiv

Yog xav paub ntxiv:

david.deng@wecistanche.com WhatApp:86 13632399501

Tsis tas li ntawd, cistanche tseem muaj cov haujlwm ntawm kev txhawb nqa collagen ntau lawm, uas tuaj yeem ua rau kom elasticity thiab luster ntawm daim tawv nqaij thiab pab kho cov tawv nqaij puas.CistanchePhenylethanol Glycosides muaj qhov cuam tshuam tseem ceeb ntawm kev ua haujlwm ntawm tyrosinase, thiab cov nyhuv ntawm tyrosinase tau pom tias muaj kev sib tw thiab thim rov qab inhibition, uas tuaj yeem muab lub hauv paus kev tshawb fawb los tsim thiab siv cov khoom xyaw whitening hauv Cistanche. Yog li ntawd, cistanche muaj lub luag haujlwm tseem ceeb hauv kev ua kom tawv nqaij. Nws tuaj yeem cuam tshuam melanin ntau lawm kom txo cov xim thiab dullness; thiab txhawb collagen ntau lawm los txhim kho daim tawv nqaij elasticity thiab radiance. Vim qhov kev lees paub dav dav ntawm cov teebmeem ntawm cistanche, ntau cov khoom siv tawv nqaij dawb tau pib infuse cov khoom xyaw tshuaj ntsuab xws li Cistanche kom tau raws li cov neeg siv khoom xav tau, yog li ua kom muaj txiaj ntsig kev lag luam ntawm Cistanche hauv cov khoom siv tawv nqaij. Hauv cov ntsiab lus, lub luag haujlwm ntawm cistanche hauv daim tawv nqaij dawb yog qhov tseem ceeb. Nws cov nyhuv antioxidant thiab collagen-tsim cov nyhuv tuaj yeem txo cov xim thiab dullness, txhim kho daim tawv nqaij elasticity thiab luster, thiab yog li ua tiav cov nyhuv whitening. Tsis tas li ntawd, daim ntawv thov dav ntawm Cistanche hauv cov khoom siv tawv nqaij ua kom pom tseeb tias nws lub luag haujlwm hauv kev lag luam tsis tuaj yeem kwv yees.

Kev sib cuam tshuam ntawm qib molecular ntawm cov tshuaj thiab cov khoom siv polymer yog qhov tseem ceeb los piav qhia txog kev ruaj ntseg hauv cov ntaub ntawv ntau npaum li cas [46]. FTIR yog cov txheej txheem tseem ceeb rau kev txiav txim siab ntawm kev sib cuam tshuam ntawm molecular ntawm cov tshuaj thiab cov polymers. Daim duab 7 qhia txog FTIR spectra ntawm CP-F ua ntej thiab tom qab khaws cia hauv cov xwm txheej sib txawv, tau txais hauv thaj tsam ntawm 4000 cm-1 txog 600 cm-1. FTIR spectrum ntawm CP pom cov qhab ntawm 1670 cm-1 hu ua C=O stretching. Cov bands ntawm 1627, 3448, thiab 3356 cm-1 sib raug rau N-H stretching ntawm CP. FTIR spectrum ntawm nanofibrous zaj duab xis dawb paug sawv cev rau qhov siab tshaj plaws ntawm 3290 cm-1 uas xa mus rau O-H stretching vibration ntawm pawg hydroxyl ntawm lub hauv paus polymer. Lub ncov ntawm 1444 thiab 2944 cm-1 xa mus rau -CH2 dabtsi yog khoov thiab C-H stretching ntawm PVA, feem [47,48]. Qhov siab tshaj plaws nqus ntawm 1696 cm−1 yog hu ua C=O los ntawm pawg amide ntawm PVP [49]. Lub ncov nyob ib ncig ntawm 1044 cm−1 yog Si–O ncab [50]. FTIR spectral qauv ntawm CP-F zoo ib yam li cov nanofibrous zaj duab xis. Qhov nqus tau siab tshaj ntawm ib ncig ntawm 1446-1440 cm-1 xa mus rau CH2 dabtsi yog khoov ntawm PVA. Qhov tsis muaj zog dav dav ntawm pawg hydroxyl ntawm 3500-3200 cm-1 spectral cheeb tsam tau muab rau O-H stretching vibration ntawm pawg hydroxyl ntawm PVA. Lub ncov tsawg zaus ntawm C=O stretching vibrations spectrum ntawm PVP los ntawm 1696 txog 1650 cm−1 tau pom thiab pom muaj zog nqus siab siab ntawm 1092 cm-1.

Nws tau raug sau tseg tias qhov tsawg zaus ntawm C=O stretching vibration ntawm 1696 cm-1 ntawm PVP nyob rau hauv lub nanofibrous zaj duab xis tau hloov mus rau 1650 cm-1 tom qab thauj CP mus rau nanofibrous zaj duab xis. Qhov no tej zaum yuav yog vim muaj kev cuam tshuam ntawm peroxide thiab PVP [51]. Tsis tas li ntawd, qhov muaj zog nqus siab siab ntawm 1044 cm-1 yog vim tus choj siloxane (Si-O-Si) ntawm cov formulations. Txawm li cas los xij, tom qab thauj CP rau zaj duab xis nanofibrous, lub ncov no tau hloov mus rau 1092 cm-1, qhia txog kev sib cuam tshuam ntawm molecular nrog tus choj siloxane. Nws tau raug tshaj tawm tias hydrogen peroxide tuaj yeem tsim muaj zog hydrogen bond nrog cov pa oxygen ntawm tus choj siloxane [52]. Lub spectral hloov siab kawg ntawm 1092 cm-1 sawv cev rau kev sib cuam tshuam ntawm hydrogen peroxide los ntawm cov molecules ntawm CP, uas adsorbed ntawm silica nto mus rau siloxane choj ntawm silica gel.

FTIR spectrum ntawm CP-F tom qab cia ntawm 25 degree / 75 feem pua ​​RH pom qhov nce ntawm qhov siab ntawm 3700-3200 cm-1. Raws li tau hais dhau los, cov ntsiab lus dej ntawm CP-F tuaj yeem nce ntxiv vim cov dej sorption ntawm CP-F thaum khaws cia hauv cov av noo siab, yog li cov qhab hauv cheeb tsam ntawm 3700-3200 cm-1 sib raug rau -OH stretching vibration ntawm hydrogen bonds ntawm dej molecules [53] Txawm li cas los xij, FTIR spectrum ntawm CP-F tom qab khaws cia ntawm 45 degree / 30 feem pua ​​​​RH nthuav tawm qhov kev siv qis heev ntawm thaj tsam ntawm 3700-3200 cm-1, thiab lub ncov ntawm 1092 cm-1 tsis tuaj. Tsuas yog qhov stretching vibration ntawm N-H ntawm 1635 cm-1 tau pom. Cov txiaj ntsig no tau qhia tias qhov kub thiab txias tuaj yeem ua rau txo qis hauv cov ntsiab lus dej thiab pawg hydroxyl [54]. Yog li ntawd, ntau lub ncov tau ploj lawm vim kev puas tsuaj los ntawm tshav kub. Qhov zoo siab, FTIR spectrum ntawm CP-F tom qab khaws cia ntawm 25 ◦C / 30 feem pua ​​RH rau 12 lub hlis tsis pom muaj kev hloov pauv hauv kev sib cuam tshuam ntawm molecular thaum lub sijhawm khaws cia. Qhov txiaj ntsig no tau qhia tias qhov xwm txheej ntawm 25 ◦C / 30 feem pua ​​RH yog qhov tsim nyog rau khaws CP-F.

3.9. Mechanical Properties Hloov tom qab Lub Sij Hawm Ntev

Cov txiaj ntsig ntawm kev cia khoom ntawm cov khoom siv kho tshuab ntawm CP-F yog qhov txaus siab. Cov txiaj ntsig raws li qhia hauv Table 5 qhia tias tsis muaj qhov sib txawv ntawm qhov sib txawv ntawm lub zog tensile, elongation ntawm kev tawg, thiab Young tus nqi ntawm kev ntsuas pib thiab tom qab cia ntawm 25 ◦C / 30 feem pua ​​RH. Txawm li cas los xij, kev hloov pauv ntawm cov khoom siv kho tshuab tau kuaj pom hauv CP-F khaws cia ntawm 25 ◦C / 75 feem pua ​​RH thiab 45 ◦C / 30 feem pua ​​RH. Cov av noo ntau dua ua rau txo qis zog tensile thiab Young tus nqi modulus ntawm CP-F, thaum feem pua ​​​​ntawm elongation thaum so tau nce ntxiv piv rau thawj tus nqi. Qhov no yuav muaj feem cuam tshuam rau cov dej molecules hauv CP-F, uas txo cov kev cuam tshuam qub hauv cov polymer matrix ntawm nanofibrous zaj duab xis [55]. Cov dej molecules tuaj yeem hloov kho cov saw hlau sib txuas los ntawm inter- thiab intramolecular hydrogen bonds [56], ua rau muaj kev nce hauv elongation thaum so thiab txo qis tensile lub zog thiab Young tus nqi modulus. Nyob rau hauv cov ntaub ntawv ntawm qhov kub siab ntawm 45 ◦C / 30 feem pua ​​RH cia, qhov txo qis hauv tensile lub zog, elongation ntawm kev tawg, thiab Young tus nqi modulus tau pom. Nws tuaj yeem raug sau tseg tias qhov kub siab dua cuam tshuam rau lub zog thiab yoog raws ntawm nanofibrous zaj duab xis, ua rau cov yeeb yaj kiab ntau dua. Cov txiaj ntsig no sib raug rau tus qauv FTIR uas qhia txog qhov tsis zoo ntawm qhov chaw cia khoom ntawm kev sib cuam tshuam molecular ntawm CP-F, yog li, kev hloov pauv hauv cov khoom siv kho tshuab kuj tshwm sim.

3.10. Adhesive Property Changes tom qab khaws cia ntev

Qhov adhesion ntawm nanofibrous zaj duab xis yog qhov tseem ceeb vim nws cuam tshuam rau kev ua haujlwm ntawm cov hniav ntxuav hniav dawb. Lub CP-F uas tau npaj tshiab tuaj yeem ua raws li qhov chaw ntawm cov mucosa thiab qhov ntsuas qhov nplaum tau pom tias yog 0.79 ± 0.07 N. Tom qab khaws cia ntawm 25 ◦ C/3{{10}} feem pua ​​RH rau 12 lub hlis, cov qauv tsis qhia qhov sib txawv tseem ceeb hauv cov khoom nplaum ntawm zaj duab xis los ntawm nws cov nqi pib. Lub zog nplaum ntawm cov zaj duab xis khaws cia yog {{20}}.75 ± 0.06 N. Lub nplaum nplaum ntawm CP-F tom qab khaws cia ntawm 25 ◦C / 75 feem pua ​​RH thiab 45 ◦ C / 30 feem pua ​​​​RH rau 12 lub hlis tau txo qis rau 0.54 ± 0.03 N thiab 0.31 ± 0.05 N, feem. Yog li ntawd nws tau pom zoo tias cov av noo thiab qhov kub thiab txias cuam tshuam rau cov khoom nplaum ntawm CP-F.

3.11. CP Tseem tshuav tom qab Lub Sij Hawm Ntev

Kev ruaj ntseg ntawm CP thaum lub sij hawm ntev cia nyob rau hauv txawv tej yam kev mob yog nthuav tawm raws li degradation profiles, raws li nyob rau hauv daim duab 8. Tom qab cia rau 12 lub hlis ntawm 25 ◦C/75 feem pua ​​RH thiab 45 ◦C/30 feem pua ​​RH , CP cov ntsiab lus tau txo qis los ntawm tus nqi pib (p <0.05). Txawm li cas los xij, CP hauv CP-F khaws cia ntawm 25 ◦C / 30 feem pua ​​RH pom tias muaj kev ruaj ntseg ntau dua li khaws cia ntawm lwm qhov chaw cia. Kev txo qis hauv CP tau pom, tsis muaj qhov sib txawv tseem ceeb hauv CP cov ntsiab lus ntawm lub sijhawm. Thaum kawg ntawm lub sijhawm xeem ntawm 12 lub hlis, cov ntsiab lus CP tseem nyob hauv qhov xwm txheej no tau pom tias muaj txog li 96.23 ± 3.05 feem pua, tom qab ntawd khaws cia ntawm 25 ◦C / 75 feem pua ​​RH (68.37 ± 4.17 feem pua). Khaws ntawm 45 ◦C / 30 feem pua ​​​​RH, CP tsis tuaj yeem pom tom qab 6 lub hlis dhau los, qhia tias tag nrho CP tej zaum yuav raug degraded tag nrho. Cov txiaj ntsig tseem qhia tau tias qhov kub thiab txias tau cuam tshuam rau CP degradation dua li cov av noo.

Raws li lub sijhawm luv luv nyob rau hauv cov kev ntxhov siab ntawm 60, 70, thiab 80◦C raws li tau hais los saum toj no, kev suav cov txee lub neej ntawm CP hauv CP-F, tau los ntawm kev kwv yees degradation tus nqi ntawm Arrhenius thaj av ntawm 25◦C, yog kwv yees li 1 xyoo. Qhov txiaj ntsig no tau pom zoo nrog qhov ntsuas qhov tseeb ntawm CP hauv CP-F khaws cia ntawm 25◦C / 30 feem pua ​​RH. Txawm li cas los xij, ntawm 25 ◦C / 75 feem pua ​​RH, cov txiaj ntsig tau pom tias CP degradation tshwm sim tom qab 3 lub hlis. Qhov txiaj ntsig no qhia tau hais tias qhov muaj av noo hauv ib puag ncig tuaj yeem ua rau CP degradation tus nqi.

4. Cov lus xaus

Cov khoom siv ntxiv:Cov hauv qab no muaj nyob online, Daim duab S1: HPLC chromatogram ntawm (a) triphenylphosphine oxide thiab residual ntawm triphenylphosphine tom qab oxidation los ntawm CP thiab (b) HPLC chromatogram ntawm triphenylphosphine.

Tus sau kev koom tes: Conceptualization, SO, PC, thiab AK; methodology, SO, PC, thiab AK; validation, TSO; kev txheeb xyuas, SO, thiab AK; kev tshawb nrhiav, AK; kev sau ntawv—kev npaj ua ntej, AK; sau ntawv- tshuaj xyuas thiab kho, SO thiab AK; kev saib xyuas, SO; kev tswj xyuas qhov project, SO; Kev nrhiav nyiaj txiag, SO Txhua tus kws sau ntawv tau nyeem thiab pom zoo rau cov ntawv luam tawm ntawm cov ntawv sau.

Nyiaj txiag: Qhov kev tshawb fawb no tau txais nyiaj los ntawm Thaib Kev Tshawb Fawb Nyiaj Txiag los ntawm Kev Tshawb Fawb thiab Kev Tshawb Fawb Kev Lag Luam (Grant No. PHD58I0012), Lub Chaw Tshawb Fawb Txog Kev Tshawb Fawb Txog Kev Ua Liaj Ua Teb, thiab Kev Tshawb Fawb Kev Kawm Qib Siab thiab National Research University Project ntawm Thaib teb, Lub Chaw Haujlwm Saib Xyuas Kev Kawm Qib Siab.

Institutional Review Board Statement: Tsis siv tau.

Cov Lus Qhia Txog Kev Pom Zoo: Tsis siv tau.

Cov ntaub ntawv muaj nyob:Cov ntaub ntawv muaj nyob rau ntawm kev thov rau tus neeg sau ntawv.

Kev lees paub:Cov kws sau ntawv ua tsaug rau Lub Chaw Tshawb Fawb ntawm Pharmaceutical Nanotechnology, Chiang Mai University, Thaib teb, rau cov khoom siv thiab kev txhawb nqa.

Kev tsis sib haum xeeb ntawm kev txaus siab: Cov kws sau ntawv tshaj tawm tsis muaj kev sib cav txog kev txaus siab.

Cov ntaub ntawv

1. Joiner, A.; Luo, W. Hniav xim thiab dawb: Kev tshuaj xyuas. J. Dent. 2017, 67, S3–S10. [CrossRef]

2. Kub, SI Cov Keeb Kwm Thaum Ntxov ntawm hydrogen peroxide siv hauv kev tu lub qhov ncauj: Daim ntawv keeb kwm. J. Periodontol. 1983, 54, 247. [CrossRef]

3. Farrell, G.; McNichols, W. Kev ua tau zoo ntawm ntau yam tshuaj hauv kev kho mob ntawm Vincent's stomatitis. J. Am. Med. Assoc. 1937, 108, 630–633 ib. [CrossRef]

4. Bonesi, CDM; Ulian, LS; Balam, P.; Angeli, VW Carbamide peroxide gel stability nyob rau hauv qhov sib txawv kub tej yam kev mob: Yog manipulated formulation ib qho kev xaiv? Braz. J. Pharm. Sci. Xyoo 2011, 47, 719–724. [CrossRef]

5. Joiner, A. Cov tshuaj ntxuav hniav dawb: Kev tshuaj xyuas cov ntaub ntawv. J. Dent. 2006, 34, 412–419. [CrossRef]

6. Dahl, JE; Pallesen, U. Hniav bleaching-Ib qho kev tshuaj xyuas tseem ceeb ntawm cov kab mob lom. Crit. Rev. Oral Biol. Med. 2003, 14, 292–304. [CrossRef]

7. Kawamoto, K.; Tsujimoto, Y. Cov teebmeem ntawm hydroxyl radical thiab hydrogen peroxide ntawm cov hniav bleaching. J. Endod. 2004, 30, 45–50. [CrossRef] [PubMed]

8. Christensen, GJ Puas yog cov hniav dawb xav tau? J. Am. Khob. Assoc. 2005, 136, 933–935. [CrossRef]

9. Putt, MS; Proskin, HM Custom tray application of peroxide gel as an adjunct to scaling and root planing in the treatment of periodontitis: Cov txiaj ntsig ntawm kev sib tw randomized tom qab rau lub hlis. J. Clin. Khob. 2013, 24, 100–107.

10. Bentley, CD; Leonard, RH; Crawford, JJ Cov nyhuv ntawm cov tshuaj ntxuav hniav dawb uas muaj carbamide peroxide ntawm cov kab mob cariogenic. J. Esthet. Xyoo 2000, 12, 33–37. [CrossRef]

11. Yao, CS; Waterfifield, JD; Shen, Y.; Hapasalo, M.; MacEntee, MI In vitro antibacterial nyhuv ntawm carbamide peroxide ntawm qhov ncauj biofilm. J. Oral Microbiol. 2013, 5, 1–6.

12. Polydorou, O.; Hellwig, E.; Auschill, TM Cov nyhuv ntawm cov tshuaj bleaching sib txawv ntawm qhov chaw zoo nkauj ntawm cov khoom siv kho dua tshiab. Ua haujlwm. Khob. 2006, 31, 473–480. [CrossRef]

13. Buchalla, W.; Attin, T. Sab nrauv bleaching txoj kev kho nrog ua kom sov, lub teeb los yog laser-A systematic tshuaj xyuas. Khob. Mater. 2007, 23, 586–596. [CrossRef] [PubMed]

14. Matis, BA; Matis, JI; Wang, Y.; Monteiro, S.; ib. Al-Qunaian, TA; Millard, R. Labeled vs. qhov tseeb concentration ntawm cov tshuaj bleaching. Ua haujlwm. Khob. Xyoo 2013, 38, 334–343. [CrossRef]

15. Blanco, M.; Coob, J.; Sánchez, MJ Kev sim tsim rau optimization ntawm peroxide formulation stability thiab nqi. J. Surfactants Deterg. 2006, 9, 341–347. [CrossRef]

16. Francine, KVM; Celso Afonso, KJ; Eduardo, GR; Rubem Beraldo, DS; Fernando Freitas, P. Keiichi, H. Cia kub cuam tshuam cov carbamide peroxide concentration ntawm cov tshuaj bleaching tom tsev. Biomed. J. Sci. Tech. Res. Xyoo 2018, 9, 6898–6902.

17. Kurthy, R. Kev tshawb fawb ntawm kev ntxuav hniav dawb gel tub yees. Ib KöR Whitening Sci. Pap. 2016, 10, 9–15.

18. Shetab Boushehri, MA; Dietrich, D.; Lamprecht, A. Nanotechnology raws li lub platform rau kev txhim kho ntawm kev txhaj tshuaj parenteral formulations: Kev tshuaj xyuas kev paub txog kev paub thiab lub xeev ntawm kos duab. Pharmaceutics 2020, 12, 510. [CrossRef]

19. Kriegel, C.; Arrechi, UA; Kev, K.; McClements, DJ; Weiss, J. Fabrication, functionalization, thiab daim ntawv thov ntawm electrospun biopolymer nanofibers. Crit. Rev. Food Sci. Nutr. Xyoo 2008, 48, 775–797. [CrossRef]

20. Persano, L.; Camposeo, UA; Tekmen, C.; Pisignano, D. Industrial upscaling of electrospinning and applications of polymer nanofibers: Kev tshuaj xyuas. Macromol. Mater. Eng. 2013, 298, 504–520. [CrossRef]

21. Tian, ​​Y.; Orlu, M.; Woerdenbag, HJ; Scarpa, M.; Kiefer, UA; Kottke, D.; Sjöholm, E.; Öblom, H.; Sandler, N.; Hinrichs, WLJ; ua al. Oromucosal films: Los ntawm tus neeg mob centricity mus rau ntau lawm los ntawm kev luam ntawv. Expert Opin. Drug Deliv. Xyoo 2019, 16, 981–993. [CrossRef]

22. Okonogi, S.; Kawpinta, A.; Rades, T.; Müllertz, A.; Yaj, M.; Khonghunthian, S.; Chaijareenont, P. Txhim khu kev ruaj ntseg thiab cov hniav ntxuav hniav dawb ntawm carbamide peroxide los ntawm electrospun nanofibrous zaj duab xis. Pharmaceuticals 2020, 13, 381. [CrossRef] [PubMed]

23. Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv. Cov lus qhia rau kev soj ntsuam kev ruaj ntseg ntawm cov khoom siv tshuaj uas muaj cov tshuaj tsim tau zoo nyob rau hauv cov ntaub ntawv ntau npaum li cas (Annex 5). Hauv WHO Technical Report Series; World Health Organization: Geneva, Switzerland, 1996; ib., 65–80.

24. Kawpinta, A.; Khonghunthian, S.; Chaijareenont, P.; Okonogi, S. Kev npaj thiab ua tus cwj pwm ntawm cov nplej gels uas muaj cov tshuaj txhuam hniav. Drug Discov. Ther. 2018, 12, 275–282. [CrossRef]

25. Stark, G.; Fawcett, JP; Tucker, IG; Weatherall, IL Instrumental ntsuam xyuas ntawm cov xim ntawm cov ntaub ntawv ntau npaum li cas thaum kuaj kev ruaj ntseg. Int. J. Pharm. 1996, 143, 93–100. [CrossRef]

26. Jantrawut, P.; Boonsermsukcharoen, K.; Thipnan, K.; Chaiwarit, T.; Hwang, KM; Park, ES Txhim kho cov kab mob tua kab mob ntawm cov txiv kab ntxwv roj hauv pectin nyias zaj duab xis los ntawm microemulsion. Nanomaterials 2018, 8, 545. [CrossRef]

27. Kawpinta, A.; Khonghunthian, S.; Chaijareenont, P.; Okonogi, S. Tooth whitening efficiency ntawm pigmented mov gels uas muaj carbamide peroxide. Drug Discov. Ther. 2018, 12, 126–132. [CrossRef]

28. Gimeno, P.; Bousquet, C.; Lus, N.; Maggio, AF; Kev, C.; Brenner, C.; ib. Lempereur, L. High-performance kua chromatography txoj kev rau kev txiav txim ntawm hydrogen peroxide tam sim no los yog tso rau hauv cov hniav bleaching cov khoom thiab cov plaub hau cosmetic khoom. J. Pharm. Biomed. Qhov quav. 2015, 107, 386–393. [CrossRef]

29. Yoshioka, S.; Stella, VJ Kev Ruaj Ntseg Ntawm Cov Ntawv Siv Tshuaj thiab Siv Tshuaj; Springer: Boston, MA, USA, 2002; Ib., 1–270.

30. Yos Hav Zoov, JP; Taube, H. The photochemical decomposition of hydrogen peroxide. J. Phys. Chem. 1952, 74, 5999–6002.

31. Lima, DANL; Aguiar, FHB; Liporoni, PCS; Munin, E.; Ambrosano, GMB; Lovadino, JR Hauv vitro kev ntsuam xyuas ntawm kev ua haujlwm ntawm cov tshuaj bleaching tau qhib los ntawm qhov sib txawv ntawm lub teeb. J. Prosthodont. 2009, 18, 249–254. [CrossRef]

32. Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv. Kev ntsuam xyuas kev ruaj ntseg ntawm cov khoom xyaw tshuaj nquag thiab cov khoom siv tshuaj tiav (Annex 10). Hauv WHO Technical Report Series, No. 1010; World Health Organization: Geneva, Switzerland, 2018; Ib., 310–351.

33. Huang, L.; Wang, S. Cov teebmeem ntawm kev kho cua sov ntawm cov khoom tensile ntawm high-strength poly (vinyl cawv) fibers. J. Appl. Polym. Sci. 2000, 78, 237–242. [CrossRef]

34. Johnston, WM; Kao, EC Kev ntsuam xyuas ntawm cov tsos zoo sib xws los ntawm kev soj ntsuam qhov muag thiab kev kho mob colorimetry. J. Dent. Res. Xyoo 1989, 68, 819–822. [CrossRef]

35. Wijanarko, TAW; Kusumaatmaja, A.; Chotimah, R.; Triyana, K. Cov nyhuv ntawm kev kho cua sov ntawm morphology thiab crystallinity ntawm electrospun poly (vinyl cawv) nanofibers. Am. Inst. Phys. Conf. Proc. 2016, 1755, 1–4.

36. Moraes, RR; Marimon, JLM; Schneider, LFJ; Correr Sobrinho, L. Camacho, GB; Bueno, M. Carbamide peroxide bleaching agents: Cov teebmeem ntawm roughness ntawm enamel, composite thiab porcelain. Clin. Qhov ncauj tshawb nrhiav. 2006, 10, 23–28. [CrossRef]

37. Ranganathan, S.; Sieber, V. Tsis ntev los no kev nce qib hauv kev sib txuas ncaj qha ntawm hydrogen peroxide siv tshuaj catalysis—Kev tshuaj xyuas. Catalysts 2018, 8, 379. [CrossRef]

38. Seif, S.; Franzen, L.; Windbergs, M. Overcoming drug crystallization in electrospun fibers—Elucidating key parameters and developing strategies for drug delivery. Int. J. Pharm. Xyoo 2015, 478, 390–397. [CrossRef] [PubMed]

39. Feng, X.; Yog, X.; Park, JB; Lu, W.; Morott, J.; Beissner, IB; Lian, ZJ; Pinto, E.; Ib, V.; Porter, S.; ua al. Kev ntsuam xyuas ntawm recrystallization kinetics ntawm kub-melt extruded polymeric khoom dispersions siv kev txhim kho Avrami sib npaug. Drug Dev. Ind. Pharm. 2015, 41, 1479–1487. [CrossRef] [PubMed]

40. Ueda, H.; Kadota, K.; Ib, M.; Ib, T.; Kunita, A.; Tozuka, Y. Co-amorphous Tsim Induced los ntawm kev sib xyaw ntawm Tranilast thiab Diphenhydramine Hydrochloride. J. Pharm. Sci. 2017, 106, 123–128. [CrossRef] [PubMed]

41. Polaskova, M.; Sib, P.; Cermak, R.; Ponizil, P. Cov nyhuv ntawm thermal kho ntawm crystallinity ntawm poly (ethylene oxide) electrospun fibers. Polymers 2019, 11, 1384. [CrossRef]

42. Rumondor, ACF; Stanford, LA; Taylor, LS Qhov cuam tshuam ntawm polymer hom thiab cia tus txheeb ze av noo ntawm kinetics ntawm felodipine crystallization los ntawm amorphous khoom dispersions. Pharm. Res. 2009, 26, 2599–2606. [CrossRef]

43. Peresin, MS; Haib, Y.; Vesterinen, AH; Rojas, OJ; Pawla, JJ; Seppälä, JV Cov nyhuv ntawm noo noo ntawm electrospun nanofiber composites ntawm poly (vinyl cawv) thiab cellulose nanocrystals. Biomacromolecules 2010, 11, 2471–2477. [CrossRef]

44. Ueda, H.; Aikawa, S.; Kasim, Y.; Kikuchi, J.; Ib, Y.; Tanino, T.; Kadota, K.; Tozuka, Y. Anti-plasticizing nyhuv ntawm amorphous indomethacin-induced los ntawm cov kev sib cuam tshuam intertermolecular nrog PVA copolymer. J. Pharm. Sci. 2014, 103, 2829–2838. [CrossRef]

45. Prudic, A.; Ji, Y.; Lusbert, C.; Sadowski, G. Kev cuam tshuam ntawm cov av noo ntawm theem tus cwj pwm ntawm API/polymer formulations. Eur. J. Pharm. Biopharm. 2015, 94, 352–362. [CrossRef]

46. ​​Tran, TTD; Tran, PHL Molecular kev sib cuam tshuam hauv cov khoom tawg ntawm cov tshuaj tsis zoo dej-soluble. Pharmaceutics 2020, 12, 745. [CrossRef]

47. Alwan, TJ; Toma, ZA; Kudhier, MA; Ziadan, KM Kev Npaj thiab kev ua tus cwj pwm ntawm PVA nanofibers ua los ntawm electrospinning. Mar. J. Nanotechnol. Nanosci. 2016, 1, 1–3. [CrossRef]

48. Subramanian, UM; Kumar, SV; Neeb, N.; Sivagnanam, UT Fabrication ntawm polyvinyl cawv-polyvinylpyrrolidone blend scaffolds ntawm electrospinning rau daim ntaub so ntswg engineering daim ntaub ntawv. Int. J. Polym. Mater. Polym. Biomater. 2014, 63, 462–470. [CrossRef]

49. Huang, S.; Zhou, L.; Li, MC; qw, w;. Kojima, Y.; Zhou, D. Kev npaj thiab cov khoom ntawm electrospun poly (vinyl pyrrolidone) / cellulose nanocrystal / silver nanoparticle composite fibers. Cov ntaub ntawv 2016, 9, 523. [CrossRef]

50. Wei, Y.; Zhang, W. Li, S.; Patel, AC; Wang, C. Electrospinning ntawm ntxeem tau silica nanofibers uas muaj nyiaj nanoparticles rau catalytic daim ntaub ntawv. Chem. Mater. 2007, 19, 1231–1238.

51. Panarin, EF; Kalninsh, KK; Pestov, DV Complexation ntawm hydrogen peroxide nrog polyvinylpyrrolidone: Ab initio xam. Eur. Polym. J. 2001, 37, 375–379. [CrossRef]

52. Zegli ´Ski, J.; Piotrowski, GP; Pieko's, R. Kev tshawb fawb txog kev sib cuam tshuam ntawm hydrogen peroxide thiab silica gel los ntawm FTIR spectroscopy thiab quantum chemistry. J. Mol. Qauv. 2006, 794, 83–91. [CrossRef]

53. Ping, ZH; Nguyen, QT; Chen, SM; Zhou, JQ; Ding, YD Cov dej hauv cov dej sib txawv hydrophilic polymers-DSC thiab FTIR kev tshawb fawb. Polymer 2001, 42, 8461–8467. [CrossRef]

54. Vasudevan, P.; Thomas, S.; Biju, PR; Sudarsanakumar, C.; Unnikrishnan, NV Synthesis thiab structural characterization of sol-gel derived titania/poly (vinyl pyrrolidone) nanocomposites. J. Sol-Gel Sci. Tshuab. 2012, 62, 41–46. [CrossRef]

55. Tian, ​​H.; Yog, J.; Rajulu, AV; Xiang, A.; Luo, X. Fabrication and properties of polyvinyl alcohol/starch blend films: Effect of composition and humidity. Int. J. Biol. Macromol. 2017, 96, 518–523. [CrossRef] [PubMed]

56. Abral, H.; Chairani, MK; Rizki, MD; Mahardika, M.; Handayani, D.; Sugiarti, E.; Muslimin, IB; Saum, SM; Ilyas, RA Tus cwj pwm ntawm compressed kab mob cellulose nano ntawv zaj duab xis tom qab raug rau qhuav thiab ntub dej. J. Mater. Res. Tshuab. 2021, 11, 896–904. [CrossRef]

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