Kev Tshawb Fawb Kev Tshawb Fawb Txog Kev Ua Haujlwm Ntawm Fecal Microbiota Transplantation hauv Kev Kho Mob Ntawm Kev Ua Haujlwm Tsis Txaus Siab
Sep 14, 2023
Chronic Functional Constipation (CFC) yog ib yam kab mob uas tshwm sim los ntawm qhov nyuaj ntawm kev tso quav, txo qhov defecation ntau zaus, thiab kev xav ntawm qhov quav tsis tiav raws li cov tsos mob tseem ceeb, thiab tsis ua raws li cov txheej txheem kuaj mob ntawm plab hnyuv siab raum. Kev tshuaj xyuas zoo los ntawm Barberio thiab al qhia tias lub ntiaj teb feem ntau ntawm cem quav yog 10.1%. Qhov tshwm sim ntawm kev cem quav hauv kuv lub tebchaws yog 8.5%. Yav dhau los, cov hau kev tseem ceeb ntawm kev kho CFC yog siv cov tshuaj laxative thiab kho cov kev ua neej nyob thiab kev noj haus. Txawm li cas los xij, qee tus neeg mob cov tsos mob tsis zoo dua tom qab kev kho mob thiab tej zaum yuav hnyav zuj zus tuaj, lossis muaj teeb meem tshwm sim. Cov neeg mob uas tau txais txiaj ntsig tsis zoo los ntawm kev saib xyuas kev kho mob yuav xav txog kev kho mob phais. Cov kev kho mob uas twb muaj lawm tsis tuaj yeem daws qhov mob ntawm CFC cov neeg mob, thiab muaj qhov yuav tsum tau ceev nrooj nrhiav kev kho kom zoo thiab muaj txiaj ntsig.
Fecal microbiota transplantation yog ib qho kev hloov pauv hauv nruab nrog cev tshwj xeeb, uas hloov fecal flora los ntawm cov neeg noj qab haus huv rau hauv cov hnyuv ntawm CFC cov neeg mob kom rov tsim cov kab mob plab hnyuv thiab kho cov txheej txheem metabolic, cov khoom, thiab cov kev taw qhia hauv lub cev. , yog li txhim kho cov tsos mob cem quav. Kev tshawb fawb txog kev siv fecal microbiota hloov pauv rau cov neeg mob CFC tau ua tiav hauv qee qhov chaw. Cov txiaj ntsig tau pom tias kev hloov pauv fecal microbiota tuaj yeem txhim kho cov tsos mob ntawm CFC cov neeg mob nyob rau lub sijhawm luv luv thiab muaj qhov tsis zoo tshwm sim tsawg dua. Txawm li cas los xij, qee cov neeg mob muaj kev ua haujlwm tsis zoo thiab qhov cuam tshuam ntev ntawm kev hloov pauv fecal microbiota yog qhov ua tau zoo yuav tsum tau txheeb xyuas. Cov kab lus no tshuaj xyuas cov kev tshawb fawb txog kev ua tau zoo ntawm fecal microbiota transplantation hauv kev kho mob ntawm CFC los muab cov ntaub ntawv siv rau kev ua kom zoo dua nws daim ntawv thov kho mob.
1. Cov neeg mob CFC
Cov yam ntxwv ntawm plab hnyuv flora
Cov kev tshawb fawb tau pom tias cov kab mob hauv plab hnyuv tsis txaus ua lub luag haujlwm tseem ceeb hauv cov kab mob ntawm CFC, uas feem ntau tshwm sim los ntawm kev txo qis hauv kev sib txawv ntawm cov hnyuv thiab txo qis hauv kev ua haujlwm anaerobes, thaum muaj cov kab mob pathogenic thiab fungi nce, ntawm qhov feem ntawm Bacteroidetes nce ntau. Bifidobacteria thiab Lactobacilli tau txo qis, thaum Kim li al pom tias cov neeg mob CFC tau txo qis Bacteroidetes. Qhov sib txawv no yuav tshwm sim los ntawm hnub nyoog, ib puag ncig, thiab kev noj haus. Nws tuaj yeem pom tau tias kev hloov pauv hauv plab hnyuv yog ib kauj ruam tseem ceeb ntawm qhov tshwm sim ntawm CFC, thiab kev tswj cov plab hnyuv kom rov qab mus rau nws qhov qub qub tuaj yeem yog tus yuam sij rau kev txo cov tsos mob ntawm tus neeg mob.
2. Kev kho mob Fecal microbiota hloov pauv
Kev ua tau zoo ntawm CFCs
Kev hloov cov kab mob Fecal yog thawj zaug siv los kho cem quav hauv xyoo 1989. Borody li al. Kev hloov pauv cov kab mob fecal los ntawm txoj hnyuv loj thiab qhov kho tau yog 36%. Ntau qhov kev sim ntsuas randomized (RCTs) hauv kuv lub tebchaws tau pom tias kev hloov pauv cov kab mob fecal muaj txiaj ntsig zoo hauv kev kho CFC dua li cov kab mob cathartics, nrog tus nqi zoo ntawm 94.23%. Raws li cov qhab nia cuam tshuam nrog cem quav, cov neeg mob cov tsos mob tshwm sim tau zoo tuaj. Zuag qhia tag nrho, lub sij hawm luv luv ntawm kev hloov cov kab mob fecal hauv cov neeg mob CFC yog qhov tseem ceeb. Txawm li cas los xij, vim nws lub sijhawm siv luv luv, kev ua haujlwm ntev yuav tsum tau kuaj xyuas, thiab RCTs feem ntau yog cov qauv me me. Cov kev tshawb fawb loj, ntau qhov chaw yuav tsum tau muaj yav tom ntej.
3. Yam uas cuam tshuam rau kev ua tau zoo ntawm kev hloov fecal
1. Tus neeg pub dawb:
Qhov ua tau zoo ntawm fecal microbiota hloov pauv kev kho mob feem ntau nyob ntawm tus neeg pub dawb. kuv lub teb chaws tus kws tshaj lij pom zoo rau cov qauv txheej txheem rau kev hloov pauv microbiota pom zoo ib tus neeg uas tsis muaj cov cim zoo hauv kev kuaj lub cev, hnub nyoog 18 txog 30 xyoo, thiab lub cev qhov hnyav ntawm 18.5 txog 23.9 kg / m2. Tus qauv pub dawb uas tau kuaj qhov tsis zoo rau cov kab mob pathogenic thiab tsis muaj keeb kwm yav dhau los. Tseem muaj cov kev xav sib txawv ntawm lub hnub nyoog thiab qhov tseeb ntawm cov neeg pub dawb. European kev pom zoo pom zoo tias cov neeg pub nyiaj yuav tsum raug xaiv los ntawm tib neeg<60 years old. Bibbò et al. believe that the optimal age of donors should be <50 years old. This is inconsistent with the Bacteroidetes and Proteus phylum in people over 70 years old. Bacteria increased. In terms of donor relatedness, the Chinese consensus recommends selecting unrelated standardized donors; while Cao et al. believe that the clinical remission rate of the unrelated donor group is slightly higher, at 36.95%. In short, standard donors should be preferred for fecal bacterial transplantation, which can avoid infection with pathogens to the greatest extent and improve the success rate and safety of transplantation. The age of the donor is controversial, and cohort studies and long-term follow-up can be conducted stratified by age group to refine the optimal age.
2. koob:
Qhov koob tshuaj ntawm fecal microbiota hloov pauv (30 ~ 100 g) muaj qhov cuam tshuam tseem ceeb ntawm kev kho tus nqi kho mob. Xyoo 2017, Tian et al. siv ib qho tshuaj hloov pauv ntawm 100 g, thiab thaum kawg 53.3% ntawm cov neeg mob cov tsos mob zoo tuaj. El-Salhy et al. pom tau hais tias qhov kev txhim kho ntawm cov tsos mob plab hauv cov neeg mob nrog kev hloov pauv koob tshuaj ntawm 60 g yog qhov siab dua li cov neeg mob hloov pauv ntawm 30 g (47.3% vs. 35.2%), thiab cov kab mob hauv plab tsis zoo yog qhov zoo dua li hauv cov neeg mob uas muaj kev hloov pauv ntawm 30 g (39% vs. 50 g). %). Ob qho tib si kuv lub teb chaws tus kws tshaj lij pom zoo rau cov txheej txheem txheej txheem thiab European kev pom zoo pom zoo kom hloov cov koob tshuaj ntau dua lossis sib npaug li 30 g. Kev nce koob tshuaj hloov pauv tuaj yeem pab txo cov tsos mob ntawm tus neeg mob, tab sis cov koob tshuaj zoo tseem tsis tau koom ua ke. Cov koob tshuaj loj tuaj yeem ncua sijhawm txij nkawm ntawm cov kab mob, tab sis seb cov kab mob loj thiab cov kab mob puas tuaj yeem ua rau cov kab mob sib kis xws li kab mob enteritis thiab septic shock? Xav tau kev tshawb nrhiav ntxiv.
3. zaus:
Tam sim no, feem ntau cov kev tshawb fawb siv ib qho kev hloov kab mob fecal. Rau cov neeg mob uas rov ua dua lossis ua tsis tau zoo ntawm kev hloov cov kab mob fecal ib zaug, ntau qhov kev hloov cov kab mob fecal tuaj yeem txiav txim siab. Kev tshawb fawb los ntawm Zhang Xuelei thiab lwm tus tau pom tias tom qab ntau qhov kev hloov cov kab mob fecal, tus neeg mob lub neej zoo tau zoo dua qub, thiab tus nqi defecation tus kheej kuj tau nce ntxiv. Kev hloov cov kab mob fecal ntau tuaj yeem txhim kho tus neeg mob lub neej zoo thiab tus nqi tshem tawm, thiab nws raug pom zoo kom siv ntau yam kab mob fecal hloov ib txwm. Tam sim no, feem ntau cov kev tshawb fawb tsuas yog tsom rau qhov koob tshuaj lossis zaus ntawm kev hloov pauv fecal microbiota, thiab muaj qee qhov kev tshawb fawb sib koom ua ke ntawm koob tshuaj thiab zaus. Qhov koob tshuaj zoo tshaj plaws ntawm kev hloov fecal microbiota ib leeg thiab ntau qhov kev hloov fecal microbiota tuaj yeem pab daws cov tsos mob. Muab ob qho tib si tshawb nrhiav qhov zoo tshaj plaws tag nrho cov tshuaj hloov pauv tuaj yeem yog cov kev taw qhia ntawm kev siv zog yav tom ntej. Raws li qhov no, nws yog ib qho tseem ceeb sib npaug los tshawb txog tag nrho cov kev kho mob thiab lub caij nyoog. Qhov muag tsis pom loj-cov qauv RCT tuaj yeem muab lub hauv paus txhim khu kev qha.
4. Txoj kev Infusion:
① Upper gastrointestinal tract txoj kev. Tam sim no, gastroscopy, gastrostomy, lossis nasojejunal raj feem ntau yog siv rau hauv plab hnyuv sab sauv. Txoj kev no yog ib qho yooj yim rau kev khiav lag luam, yuav tsum muaj cov kab mob fecal tsawg dua, thiab muaj kev nyab xeeb. Txawm li cas los xij, nws yog ib qho nyuaj los xyuas kom meej tias cov kua fecal kab mob kis thoob plaws hauv tag nrho cov hnyuv, uas cuam tshuam rau kev ua tau zoo. Kev tshawb nrhiav rov qab tau pom tias rau cov neeg mob uas muaj cem quav qeeb, transnasointestinal tube fecal bacterial transplantation muaj qhov kev kho mob ntau dua li cov kab mob colonoscopy (74.2% vs. 53.3%) thiab qis dua qhov tshwm sim tsis zoo (39.2% vs. 76.7%). Tian Hongliang thiab lwm tus tau pom tias kev tswj hwm qhov ncauj ntawm cov kab mob nyob hauv cov hmoov qhuav qhuav tau ua rau muaj kev txhim kho kev kho mob zoo dua thiab txo qis qhov tshwm sim tsis zoo hauv cov neeg mob nrog cem quav qeeb, tab sis cov txiaj ntsig kho tau poob qis dhau sijhawm. Cov kab mob Fecal yog ib qho yooj yim khaws cia, tab sis lawv cov txiaj ntsig thiab kev ruaj ntseg yuav tsum tau tshawb xyuas los ntawm kev soj ntsuam mus sij hawm ntev ntawm cov plab hnyuv siab raum thiab cov ntsuas ntsuas (xws li fecal flora composition thiab gastrointestinal hormone theem). Tsis tas li ntawd, tshem tawm cov kab mob uas muaj txiaj ntsig zoo rau kev txhim kho cem quav thiab npaj cov kab mob fecal kab mob tuaj yeem txhim kho qhov kev kho mob ntawm cov neeg mob.
② Mid-digestive tract mus kom ze: Qhov nruab nrab-digestive tract mus kom ze yog ib txoj hauv kev tshiab los ntawm xibfwb Zhang Fangfa. Nws feem ntau yog hais txog endoscopic plab hnyuv grafting, uas siv titanium clips los kho cov hlab ntsha hauv cov hnyuv raws li qhov pom kev ncaj qha. Qhov kev siv tshuab endoscopic no tuaj yeem ua tiav tag nrho cov khoom siv hauv plab hnyuv, nrog rau tus neeg mob txaus siab ntawm 98.1%. Yog tias yuav tsum tau hloov cov kab mob fecal ntau, endoscopic plab hnyuv grafting tuaj yeem txiav txim siab, tab sis tam sim no tsis tshua siv thiab feem ntau yog siv rau cov neeg mob uas mob plab hnyuv thiab tsis tshua siv rau cov neeg mob CFC. Yog li ntawd, RCTs nrog cov qauv loj thiab cov kev txwv nruj thiab kev cais tawm tseem xav tau los tshawb nrhiav kev ua haujlwm ntawm fecal microbiota hloov pauv los ntawm nruab nrab-GI ib puag ncig hauv CFC thiab nws cov txiaj ntsig hauv kev ua raws li tus neeg mob.
③ Cov kab mob hauv plab qis dua: Kev hloov cov kab mob Fecal yog ua los ntawm colonoscopy, sigmoidoscopy, enema, thiab lwm yam. Qhov kev ua tau zoo tag nrho yog txhim khu kev qha, tab sis qhov tshwm sim ntawm qhov tshwm sim tsis zoo yog siab. Tam sim no, retention enema yog txoj kev siv tau zoo tshaj plaws rau cov neeg mob, tab sis qhov chaw uas cov kab mob fecal tov tuaj yeem ncav cuag tau txwv, thiab nws nyuaj rau kev ua haujlwm zoo rau cov kab mob plab hnyuv siab tshaj cov hnyuv sigmoid. Colonoscopy tuaj yeem tua cov kab mob fecal zoo, tab sis nws tsis zoo los ntawm cov neeg mob thiab ua rau muaj kev pheej hmoo ntawm perforation. Nyob rau tib lub sijhawm, nws yog qhov nyuaj rau cov kab mob fecal kua khaws cia rau hauv txoj hnyuv mus ntev. Tian Hongliang thiab lwm tus tau pom tias qhov ua tau zoo ntawm kev hloov cov kab mob fecal los ntawm colonoscopy yog 53.3%, thiab qhov tshwm sim ntawm kev tsis zoo yog 76.7%. Tam sim no, txoj hauv kev zoo tshaj plaws rau kev hloov pauv fecal microbiota tseem tsis tau txiav txim siab. Nws yuav tsum tau txiav txim siab raws li tus yam ntxwv ntawm tus kab mob thiab tus neeg mob tus mob. Muaj qee qhov kev tshawb fawb txog nws daim ntawv thov hauv CFC. Ntau cov kev tshawb fawb los yog RCTs nrog cov qauv loj loj yuav tsum tau muaj yav tom ntej kom paub meej cov txiaj ntsig. Cov kab mob fecal sib txawv ntawm kev hloov pauv kab mob muaj lawv qhov zoo. Kev sib xyaw ua ke ntau txoj hauv kev rau kev hloov pauv tuaj yeem ua qhov tseem ceeb ntawm kev tshawb fawb yav tom ntej. Piv txwv li, kev sib xyaw ua ke ntawm nasojjunal raj thiab colonoscopy tuaj yeem ua tiav tag nrho txoj hnyuv hauv plab thiab ua kom cov ntsiab lus ntawm cov kab mob fecal ntau npaum li sai tau, tab sis nws tuaj yeem ua haujlwm tau zoo yuav tsum tau soj ntsuam tshwj xeeb.
5. Kev Kho Kom Zoo:
Cov kev tshawb fawb yav dhau los tau pom tias kev hloov pauv cov kab mob fecal ib leeg muaj kev nyab xeeb thiab siv tau zoo hauv kev kho CFC, thiab qee cov kws tshawb fawb tau ua ke nrog cov tshuaj laxatives. Kev tshawb fawb los ntawm Liu Qiaoyun thiab lwm tus tau pom tias qhov kev kho mob thiab kev txhim kho ntawm cov kab mob fecal hloov pauv nrog polyethylene glycol yog 37.1% thiab 77.1% raws li, thiab tus neeg mob lub siab lub ntsws thiab lub neej zoo tau zoo tuaj. Zhang et al. tau ua 1-xyoo kev soj ntsuam ntawm cov neeg mob uas sib xyaw cov kab mob fecal hloov pauv thiab pectin thiab pom tias kev kho mob ua ke tau zoo dua (kev kho mob thiab kev txhim kho tus nqi yog 69.0% thiab 75.9%, feem) , tab sis qhov kev ua tau zoo yog qhov tsis zoo thaum kawg ntawm kev ua raws. poob. Nws tuaj yeem pom tau tias kev hloov pauv cov kab mob fecal nrog rau cov tshuaj laxatives ib txwm muaj kev ntseeg siab nyob rau lub sijhawm luv luv, tab sis cov nyhuv ntev yuav tsum tau lees paub los ntawm cov ntaub ntawv loj nrog kev soj ntsuam ntawm 3 mus rau 5 xyoo lossis ntau dua. Nyob rau tib lub sijhawm, kev tsom xam stratified, Cox regression, thiab lwm yam tuaj yeem siv tau. Kev hloov kho rau cov teeb meem tsis meej pem tau tsim los txhim kho kev ntseeg siab ntawm cov txiaj ntsig.
Cov kev tshawb fawb tau pom tias kev hloov pauv fecal microbiota ua ke nrog kev kho mob biofeedback zoo dua, thiab cov tshuaj tua kab mob thiab cov tshuaj suav tshuaj muaj txiaj ntsig zoo hauv kev txo cov tsos mob ntawm cov neeg mob CFC. Kev sib xyaw ua ke nrog fecal microbiota hloov pauv tuaj yeem pab cov neeg mob rov zoo. Yang et al. pom tias fecal microbiota transplantation ua ke nrog biofeedback kev kho mob rau CFC tuaj yeem ua rau kom muaj qhov tso zis ntau zaus, txhim kho cov neeg mob lub neej zoo, thiab txhim kho kev sib txawv ntawm cov kab mob hauv cov neeg mob cov hnyuv. Rifaximin, vancomycin, thiab lwm yam tshuaj tua kab mob tuaj yeem cuam tshuam qhov kev loj hlob ntawm Enterococcus faecalis thiab Escherichia coli thiab rov tsim kho lub plab hnyuv microecology, uas muab lub tswv yim tshiab rau kev kho mob ntawm cov kab mob fecal transplantation. Kev sib raug zoo ntawm cov tshuaj suav tshuaj thiab cem quav ntev tau kawm dav. Qee cov tshuaj suav tshuaj tuaj yeem ua rau cov tshuaj hormones digestinal hauv cov neeg mob thiab muaj cov nyhuv laxative pom tseeb. Piv txwv li, kev hloov cov kab mob fecal ua ke nrog Liuwei Nengxiao capsule tuaj yeem txhim kho cov tsos mob cem quav ntawm cov neeg mob CFC, qhia tias kev hloov cov kab mob fecal nrog rau cov tshuaj suav tshuaj suav tias yog txoj kev kho tshiab rau CFC. Txawm li cas los xij, vim muaj cov qauv me me thiab qhov muaj nyob ntawm kev xaiv tsis ncaj ncees hauv txoj kev tshawb no, kev hloov kho ntawm kev kho mob tseem xav tau kev kawm ntxiv. Nws tseem yuav tsum tau ua los ntawm kev nce tus qauv loj thiab nruj me ntsis tsim kev suav nrog thiab tsis suav nrog. Tus qauv, daim ntawv thov ntawm propensity matching thiab lwm txoj kev los txo cov kev cuam tshuam ntawm confounding yam ntawm cov kev tshwm sim.
4. Kev hloov pauv Fecal microbiota
kev kho mob mechanism
1. Hloov cov kab mob hauv plab hnyuv:
Tom qab kev kho mob nrog fecal microbiota hloov pauv, ntau haiv neeg ntawm cov kab mob hauv tus neeg mob lub cev tau nce ntxiv, sib tw nrog cov kab mob tsis zoo kom loj hlob, inhibiting lawv cov kev tsim tawm thiab tsim cov co toxins, thiab tib lub sij hawm inducing cov kev qhia ntawm transcription factor aryl hydrocarbon receptor los txhim kho colonic. kev txav chaw. Tom qab hloov fecal, tus naj npawb ntawm Bifidobacteria thiab Lactobacilli nyob rau hauv txoj hnyuv ntawm cov neeg mob nce, thiab tus naj npawb ntawm Bacteroidetes thiab Firmicutes txo. Bifidobacteria thiab Lactobacilli tuaj yeem qhib lub chromogranin A / 2A adrenergic receptor cascade signaling thiab hloov kho lub sijhawm hloov pauv receptor muaj peev xwm / tryptophan hydroxylase-olfactory receptor txoj hauv kev los txhawb 5-hydroxytryptamine secretion. Tsis tas li ntawd, cov poov xab cov ntsiab lus nyob rau hauv tus neeg mob cov hnyuv tau txo, uas tej zaum yuav muaj feem xyuam rau cov tsos mob ntawm cem quav.
2. Kho lub plab zom mov cov tshuaj hormones:
Tom qab kev kho mob fecal microbiota hloov pauv, tus neeg mob cov ntshav qib ntawm 5-hydroxytryptamine, acetylcholine, motilin, thiab tshuaj P tau nce ntxiv. Kev khi ntawm serotonin rau nws cov receptor activates serotonin 4-zoo enteric neurons, yog li txhawb txoj hnyuv motility. Kev tso tawm ntau ntxiv ntawm acetylcholine, tshuaj P, thiab motilin tuaj yeem txhawb kev zom zaub mov ntawm cov leeg nqaij thiab plab hnyuv, yog li txhim kho cov tsos mob cem quav.
3. Tswj cov txheej txheem metabolic thiab cov khoom lag luam:
Butyrate ntau lawm nyob rau hauv cov neeg mob kho nrog fecal microbiota transplantation yog ho nce. Butyrate tsis yog tsuas yog lub zog tseem ceeb ntawm cov hnyuv epithelial hlwb, tab sis kuj tuaj yeem ua rau cov kab mob colonic. Xie et al. pom tias metabolites ntawm kev zom cov protein thiab kev nqus ntawm cov neeg mob (xws li phenylalanine, indoleacrylic acid, N-acetyl-L-glutamic acid, thiab lwm yam) tau nce ntau. Yog li, nws tau kwv yees tias kev hloov pauv ntawm cov kab mob fecal tuaj yeem tswj hwm kev zom zaub mov thiab nqus tau los txhim kho cem quav.
5. Cov teeb meem uas yuav tsum tau kawm yav tom ntej
Kev hloov pauv Fecal microbiota yuav tsum tau ua haujlwm nruj thiab ua qauv, thiab cov neeg mob cov xwm txheej sib txawv, ua rau nws nyuaj rau kev tsim cov phiaj xwm kev sib koom ua ke. Ib qho kev npaj hloov pauv ntawm tus neeg mob fecal microbiota yuav tsum tau tsim raws li tus neeg mob tus mob, thiab kev soj ntsuam mus sij hawm ntev yuav tsum tau ntsuas qhov ua tau zoo mus ntev. Cov tshuaj muaj pes tsawg leeg ntawm cov kab mob fecal kua rho tawm ncaj qha los ntawm cov quav yog complex, thiab cov kab mob kab mob tsis meej kiag li. Yuav ua li cas kom tshem tawm cov kab mob muaj txiaj ntsig zoo rau kev kho CFC los ntawm cov quav thiab nws qhov sib piv yog lub hom phiaj ntawm kev tshawb fawb yav tom ntej. Formulated flora transplantation thiab fecal artificial flora Lub tswv yim kho mob taw qhia rau cov lus qhia rau kev tshawb fawb yav tom ntej. Tsis tas li ntawd, piv nrog cov kab mob fecal yooj yooj yim, kev sib xyaw ua ke ntawm CFC nrog cov tshuaj laxatives, tshuaj tua kab mob, biofeedback kho, tshuaj suav tshuaj, thiab lwm yam kuj yog cov kev taw qhia ntawm kev siv zog yav tom ntej.
Ntuj Herbal Tshuaj Rau Relieving cem quav-Cistanche
Cistanche yog ib tug genus ntawm parasitic nroj tsuag uas belongs rau tsev neeg Orobanchaceae. Cov nroj tsuag no paub txog lawv cov khoom siv tshuaj thiab tau siv hauv Cov Tshuaj Suav Tshuaj (TCM) rau ntau pua xyoo. Cov hom Cistanche feem ntau pom muaj nyob hauv thaj av qhuav thiab suab puam ntawm Tuam Tshoj, Mongolia, thiab lwm qhov chaw ntawm Central Asia. Cistanche nroj tsuag yog tus cwj pwm los ntawm lawv cov nqaij tawv, yellowish stems thiab muaj nuj nqis heev rau lawv cov txiaj ntsig kev noj qab haus huv. Hauv TCM, Cistanche ntseeg tau tias muaj cov khoom siv tonic thiab feem ntau yog siv los kho lub raum, txhim kho qhov tseem ceeb, thiab txhawb kev ua haujlwm ntawm kev sib deev. Nws kuj yog siv los daws cov teeb meem ntsig txog kev laus, qaug zog, thiab kev noj qab haus huv tag nrho. Thaum Cistanche muaj keeb kwm ntev ntawm kev siv tshuaj ib txwm siv, kev tshawb fawb tshawb fawb txog nws txoj kev ua tau zoo thiab kev nyab xeeb tsis tu ncua thiab txwv. Txawm li cas los xij, nws paub tias muaj ntau yam bioactive tebchaw xws li phenylethanoid glycosides, iridoids, lignans, thiab polysaccharides, uas tuaj yeem ua rau nws cov teebmeem tshuaj.
Wecistanche covcistanche hmoov, cistanche ntsiav tshuaj, cistanche capsules, thiab lwm yam khoom tsim los sivsuab puamcistancheraws li cov khoom siv raw, txhua yam muaj txiaj ntsig zoo rau kev tshem tawm cem quav. Cov txheej txheem tshwj xeeb yog raws li hauv qab no: Cistanche ntseeg tau tias muaj cov txiaj ntsig zoo rau kev tshem tawm cem quav raws li nws cov kev siv ib txwm siv thiab qee cov tshuaj uas nws muaj. Txawm hais tias kev tshawb fawb tshawb fawb tshwj xeeb ntawm Cistanche qhov cuam tshuam rau cem quav yog txwv, nws tau xav tias muaj ntau lub tswv yim uas yuav ua rau nws muaj peev xwm txo tau cem quav. Laxative nyhuv:Cistanchetau ntev tau siv nyob rau hauv tsoos suav tshuaj raws li ib tug tshuaj rau cem quav. Nws ntseeg tau tias muaj cov nyhuv laxative me me, uas tuaj yeem pab txhawb kev zom zaub mov thiab ua rau cem quav. Cov nyhuv no tuaj yeem raug ntaus nqi rau ntau lub tebchaw nyob hauv Cistanche, xws li phenylethanoid glycosides thiab polysaccharides. Moistening cov hnyuv: Raws li kev siv ib txwm siv, Cistanche suav hais tias muaj cov khoom siv moisturizing, tshwj xeeb yog tsom rau cov hnyuv. Txhawb nqa dej thiab lubrication ntawm cov hnyuv yuav pab tau cov cuab yeej soften thiab yooj yim dua, yog li no relieving cem quav. Anti-inflammatory Effect: cem quav tej zaum yuav txuam nrog o nyob rau hauv lub plab zom mov. Cistanche muaj qee qhov sib txuas, suav nrog phenylethanoid glycosides thiab lignans, uas ntseeg tau tias muaj cov tshuaj tiv thaiv kab mob. Los ntawm kev txo cov kab mob hauv cov hnyuv, nws tuaj yeem pab txhim kho kev zom zaub mov tsis tu ncua thiab txo qhov cem quav.
