Kev Tshawb Fawb Kev Txhim Kho ntawm Lactulose Hauv Kev Npaj plab hnyuv hauv cov neeg mob nrog cem quav Ⅲ
Aug 23, 2023
04 Lactulose ua ke nrog PEG rau kev npaj plab hnyuv hauv cov neeg mob cem quav
Kev soj ntsuam soj ntsuam thiab kev tshawb fawb tau pom tias cov neeg mob cem quav mus ntev muaj qhov tsis zoo rau kev npaj plab hnyuv. Suav cov lus qhia [10] pom zoo tias cov tshuaj ntxuav PEG yuav tsum noj ob zaug, thiab cov tshuaj laxatives (xws li Pixacol) yuav tsum noj 2 mus rau 3 hnub ua ntej kev npaj plab hnyuv. pyridine, senna, phenolphthalein, thiab lwm yam).
Lu J et al [38] tau kawm txog kev npaj plab hnyuv ntawm lactulose + polyethylene glycol electrolyte hmoov (Polyethylene glycol electrolyte hmoov, PEG-EP) thiab PEG-EP ib leeg rau cov neeg mob cem quav. Lactulose qhov ncauj tshuaj thiab PEG-EP tau muab, thaum pab pawg tswj tau tsuas yog muab PEG-EP.
Tom qab ntawd ua raws li cov lus qhia hauv qab no: lub sijhawm tso tseg thawj zaug (lub sijhawm los ntawm kev noj cov tshuaj mus rau thawj qhov tso quav), zaus ntawm qhov tso quav, lub sijhawm kom ua tiav qhov quav (lub sijhawm los ntawm thawj qhov quav mus rau lub sijhawm thaum cov quav pom tseeb), thiab kev phiv tshuaj. Cov txiaj ntsig ntawm kev ntxuav lub plab hauv pawg kev tshawb fawb tau zoo dua li qhov hauv pawg tswj hwm (P < 0.05). Ntawm lawv, thawj lub sijhawm defecation thiab lub sijhawm defecation tiav ntawm pab pawg kawm tau ntxov dua li ntawm pawg tswj hwm (P<0.05), and the number of defecation was significantly higher than that of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). The combined application of lactulose oral solution and PEG-EP is superior to the traditional method of PEG-EP alone for colonoscopy bowel preparation in patients with constipation.
Yog li ntawd, kev sib xyaw ntawm ob lub tebchaw rau kev npaj plab hnyuv colonoscopic hauv cov neeg mob cem quav yog pom zoo rau kev siv tshuaj kho mob. Txoj kev tshawb no los ntawm Wang Qiao et al. [39] suav nrog 148 tus neeg mob, 74 tus neeg mob hauv pawg soj ntsuam thiab 74 tus neeg mob hauv pawg tswj hwm. Hauv pab pawg soj ntsuam, kev ua kom huv ntawm plab hnyuv tau zoo heev hauv 29 tus neeg mob, zoo hauv 34 kis, ncaj ncees hauv 10 kis, thiab tsis zoo hauv 1 kis. Tag nrho cov txiaj ntsig tau zoo yog 85%. . 1% yog '; 19, 27, 21, 7 mob thiab 62. 2% hauv pawg tswj hwm; qhov kev sib piv ntawm tag nrho cov txiaj ntsig zoo ntawm ob pawg, P < 0. 01. Qhov kev vam meej ntawm colonoscopy hauv pawg soj ntsuam yog 95.9%, uas yog qhov siab tshaj 85.1% hauv pawg tswj hwm (P<0.01). The acceptability of colonoscopy in the observation group was 93.2%, which was significantly higher than that in the control group (81.1% (P < 0.05). There were no serious adverse events in the two groups, and there was no statistically significant difference in the incidence of adverse reactions.
Txoj kev tshawb no xaus lus tias cov khoom sib xyaw PEG-EP ua ke nrog lactulose muaj kev huv huv ntawm plab hnyuv ua ntej colonoscopy hauv cov neeg mob cem quav, kev ua tau zoo ntawm kev kuaj microscopic, kev lees paub ntawm cov neeg mob siab, thiab kev nyab xeeb zoo. Ib yam li ntawd, qee tus kws tshawb fawb [40] tau ua kev tshawb fawb. Hauv txoj kev tshawb no, cov neeg mob tau muab faib ua pawg lactulose thiab pawg tswj hwm, nrog rau 60 tus neeg mob hauv txhua pab pawg. Lactulose qhov ncauj kua tau siv rau kev npaj plab hnyuv hauv pab pawg lactulose, thiab cov tshuaj PEG-EP tau siv rau pawg tswj hwm. Kev npaj plab hnyuv.
Tom qab cov neeg mob noj cov tshuaj, qhov kev tsis zoo tshwm sim, kev ua kom lub plab zom mov, thiab kev ua siab ntev ntawm cov neeg mob tau raug soj ntsuam. Cov txiaj ntsig tau pom tias tom qab ob pawg ntawm cov neeg mob tau txais cov tshuaj sib xws los ntxuav cov hnyuv, feem ntau ntawm cov tshuaj tiv thaiv tsis zoo xws li mob plab, mob plab, qaug zog, xeev siab, ntuav, thiab kiv taub hau hauv pab pawg lactulose tau qis dua qhov ntawd. nyob rau hauv pawg tswj (P < 0.05), thiab pawg tswj tau muaj ntau tus neeg mob nyob rau hauv qib Ⅲ thiab qib Ⅳ (kev ua kom lub plab huv si) dua li cov nyob rau hauv pawg lactulose (P<0. 05).
Yu Zhibin et al. [41] Kev sib piv tau kawm txog cov txiaj ntsig ntawm compound PEG-EP ib leeg (paub A), compound PEG-EP + lactulose qhov ncauj kua (pawg B), thiab compound PEG-EP + senna (paub C) ntawm txoj hnyuv hauv txoj kev tshawb no, 1{ {15}}8 cov neeg mob tau suav nrog, thiab cov qhab nia ntawm plab hnyuv thiab qhov ua tau zoo ntawm peb pawg tau muab piv rau (Pab A 5. 11 ± 1. 02, 66. 7%; Pawg B 7. 96 ± { {34}}. 75, 94. 3%; Pawg C 5. 83 ± 1. 13, 22. 2%), tag nrho cov qhab nia thiab kev ua tau zoo ntawm pawg B tau siab dua cov pab pawg A thiab C, thiab qhov sib txawv yog qhov tseem ceeb (P ＜ 0. 05); Qhov tshwm sim ntawm kev mob plab hnyuv xws li ntuav thiab mob plab hauv pawg B yog qis dua li ntawm pawg C (2. 7% thiab 8. 3% hauv pawg B, 13. 8% thiab 25% hauv pawg C), thiab Qhov sib txawv yog qhov tseem ceeb (P < 0. 05), tsis muaj qhov sib txawv tseem ceeb hauv kev ua raws li kev noj tshuaj ntawm peb pawg (Class I: 66. 7% hauv pawg A, 63. 8% hauv pawg B, thiab 55. 6% hauv Pawg C).
Sun Yiyi et al[42] coj mannitol + castor roj los ua pawg tswj hwm, thiab lactulose + compound PEG-EP raws li pab pawg soj ntsuam, thiab muab piv rau qhov ua tau zoo ntawm kev kuaj kab mob colonoscopy, qhov zoo ntawm kev npaj plab hnyuv thiab kev tsis zoo ntawm ob pawg. tom qab noj tshuaj. Cov txiaj ntsig Kev ntsuam xyuas kev ua tiav ntawm pawg soj ntsuam yog 97.1%, ntau dua li ntawm pawg tswj hwm (88.6%), thiab qhov sib txawv ntawm ob pawg yog qhov tseem ceeb (P<0.05); the bowel preparation quality of the observation group was The efficiency was 94. 3%, which was significantly higher than 81. 4% in the control group (P ＜ 0. 05); the incidence of adverse reactions in the observation group was 4. 3%, which was significantly lower than 12. 9% in the control group (P ＜ 0. 05).
Cov kev tshawb fawb saum toj no tag nrho qhia tau hais tias lactulose ua ke nrog PEG tuaj yeem ua rau muaj kev huv huv ntawm cov hnyuv thiab txo cov tshuaj tsis zoo rau cov neeg mob cem quav. Kev nyab xeeb thiab kev ua tau zoo ntawm txoj kev npaj yuav tsum tau tshawb nrhiav ntxiv.
05 Cov ntsiab lus
Txoj kev chinesoscopy yog ib txoj kev tseem ceeb los xyuas cov xim txhab xim, thiab cem quav yuav cuam tshuam rau kev npaj ua kom huv thiab txo cov tshuaj tiv thaiv kev mob plab hnyuv. Kev tshawb fawb tam sim no qhia tau hais tias kev siv lactulose ua ke nrog PEG rau kev npaj plab hnyuv tuaj yeem txhim kho txoj hnyuv ntawm cov neeg mob cem quav Txawm li cas los xij, kev siv tshuaj ntau npaum li cas thiab siv sijhawm ntawm lactulose ua ke nrog PEG tseem xav tau kev tshawb fawb ntxiv.
Ntuj Herbal Tshuaj Rau Relieving cem quav-Cistanche
Cistanche yog ib tug genus ntawm parasitic nroj tsuag uas belongs rau tsev neeg Orobanchaceae. Cov nroj tsuag no paub txog lawv cov khoom siv tshuaj thiab tau siv hauv Cov Tshuaj Suav Tshuaj (TCM) rau ntau pua xyoo. Cov hom Cistanche feem ntau pom muaj nyob hauv thaj av qhuav thiab suab puam ntawm Tuam Tshoj, Mongolia, thiab lwm qhov chaw ntawm Central Asia. Cistanche nroj tsuag yog tus cwj pwm los ntawm lawv cov nqaij tawv, yellowish stems thiab muaj nuj nqis heev rau lawv cov txiaj ntsig kev noj qab haus huv. Hauv TCM, Cistanche ntseeg tau tias muaj cov khoom siv tonic thiab feem ntau yog siv los kho lub raum, txhim kho qhov tseem ceeb, thiab txhawb kev ua haujlwm ntawm kev sib deev. Nws kuj yog siv los daws cov teeb meem ntsig txog kev laus, qaug zog, thiab kev noj qab haus huv tag nrho. Thaum Cistanche muaj keeb kwm ntev ntawm kev siv tshuaj ib txwm siv, kev tshawb fawb tshawb fawb txog nws txoj kev ua tau zoo thiab kev nyab xeeb yog tsis tu ncua thiab txwv. Txawm li cas los xij, nws paub tias muaj ntau yam bioactive tebchaw xws li phenylethanoid glycosides, iridoids, lignans, thiab polysaccharides, uas tuaj yeem ua rau nws cov teebmeem tshuaj.
Wecistanche covcistanche hmoov, cistanche ntsiav tshuaj, cistanche capsules, thiab lwm yam khoom tsim los sivsuab puamcistancheraws li cov khoom siv raw, txhua yam muaj txiaj ntsig zoo rau kev tshem tawm cem quav. Cov txheej txheem tshwj xeeb yog raws li hauv qab no: Cistanche ntseeg tau tias muaj cov txiaj ntsig zoo rau kev tshem tawm cem quav raws li nws cov kev siv ib txwm siv thiab qee cov tshuaj uas nws muaj. Txawm hais tias kev tshawb fawb tshawb fawb tshwj xeeb ntawm Cistanche qhov cuam tshuam rau cem quav yog txwv, nws tau xav tias muaj ntau lub tswv yim uas yuav ua rau nws muaj peev xwm txo tau cem quav. Laxative nyhuv:Cistanchetau ntev tau siv nyob rau hauv tsoos suav tshuaj raws li ib tug tshuaj rau cem quav. Nws ntseeg tau tias muaj cov nyhuv laxative me me, uas tuaj yeem pab txhawb kev zom zaub mov thiab ua rau cem quav. Cov nyhuv no tuaj yeem raug ntaus nqi rau ntau lub tebchaw nyob hauv Cistanche, xws li phenylethanoid glycosides thiab polysaccharides. Moistening cov hnyuv: Raws li kev siv ib txwm siv, Cistanche suav hais tias muaj cov khoom siv moisturizing, tshwj xeeb yog tsom rau cov hnyuv. Los ntawm kev txhawb hydration thiab lubrication ntawm cov hnyuv, nws yuav pab tau soften cov cuab yeej thiab pab kom yooj yim dua, li no relieving cem quav. Anti-inflammatory Effect: cem quav tej zaum yuav txuam nrog o nyob rau hauv lub plab zom mov. Cistanche muaj qee qhov sib txuas, suav nrog phenylethanoid glycosides thiab lignans, uas ntseeg tau tias muaj cov tshuaj tiv thaiv kab mob. Los ntawm kev txo cov kab mob hauv cov hnyuv, nws tuaj yeem pab txhim kho kev zom zaub mov tsis tu ncua thiab txo qhov cem quav.
