Polyvisceral Polycystic Disease-a Case Study And Review
Apr 19, 2023
Abstract
Polycystic raum kab mob (PKD) tshwm sim li ntawm ib ntawm 20,000 yug. Nws yog qhov tsis tshua muaj cysts hauv lwm yam kabmob xws li qog adrenal, daim siab, thiab zais zis. Kev tshuaj xyuas cov ntaub ntawv, muaj pov thawj tias PKD tshwm sim ua ke nrog cov kab mob siab polycystic, tab sis txog niaj hnub no, tsis muaj cov kab mob sib kis tau tshaj tawm. Kev kuaj mob ntawm tus menyuam hauv ib lub lis piam 36- pom muaj ntau yam kab mob hauv lub raum, siab, qog adrenal, thiab zais zis. Cov ntaub ntawv histopathological ntxiv tau lees paub qhov kev kuaj mob ntawm tus kab mob polycystic raum. Keeb kwm ntawm yav dhau los hauv-utero tuag ntawm lwm tus menyuam ntawm 28 lub lis piam ntawm cev xeeb tub qhia pom tias muaj tsev neeg phenotype. Consecutive prenatal ultrasounds tsis qhia txawv txawv, hais txog lub luag hauj lwm tseem ceeb ntawm fetal autopsy nyob rau hauv cov ntsiab lus ntawm tsis tiav obstetric keeb kwm. Kev kuaj mob ntawm fetal anomalies yog pab tau rau cov niam txiv sab laj txog qhov rov tshwm sim ntawm cev xeeb tub tshiab.
Ntsiab lus
Polycystic raum kab mob; Kev kuaj mob; Chromosomal microarray;Cistanche cov teebmeem.
Nyem qhov no kom paubcov txiaj ntsig ntawm Cistanche.
Taw qhia
Kev loj hlob ntawm fetal yog ib qho txheej txheem nyuaj uas tau teeb tsa hauv lub sijhawm thiab hierarchy. Kev cuam tshuam hauv kev sib nrig sib qhia thaum lub sij hawm embryogenesis yog lub luag haujlwm rau ntau yam kev loj hlob tsis xws luag. Congenital anomalies ntawm lub raum thiab urinary tract (CAKUT) account rau ib feem peb ntawm tag nrho cov congenital malformations thiab kwv yees yuav tshwm sim nyob rau hauv 3-6 mob rau 1000 nyob yug. Lub raum fetal anomalies ib leeg suav txog 20 feem pua ntawm fetal congenital defects. Cov kab mob hauv lub raum tsis zoo muaj xws li ntau yam kab mob nrog txoj kev pathophysiology, sib txawv cov txiaj ntsig kev kho mob, thiab kev cuam tshuam txog kev tswj hwm. Cov kab mob hauv lub raum no muaj feem cuam tshuam rau cov menyuam mos thiab menyuam mos thiab kev tuag.
Cov kab mob polycystic raum (PKD) yog ib hom kab mob sib txawv hauv kev kho mob thiab kab mob sib txawv uas suav nrog ntau hom kab mob thiab tsis muaj kab mob, piv txwv li, ib leeg lossis ob sab; cais los yog tshaj tawm cysts; lub raum los yog extrarenal kev koom tes. PKD yog ib qho kev hnov mob ciliopathy nrog nce kev loj hlob thiab nce apoptosis. PKD muaj cov kab mob nyuaj uas cuam tshuam nrog ntau txoj hauv kev molecular uas sib tshooj, ntxiv, lossis tawm tsam ib leeg. Lub raum abnormalities tuaj yeem tshwm sim ib leeg lossis ua ke nrog lwm yam txawv txav lossis cov tsos mob. Lawv feem ntau tshwm sim hauv cov menyuam mos thiab menyuam yaus thiab suav nrog autosomal dominant polycystic raum kab mob (ADPKD), autosomal recessive polycystic raum kab mob (ARPKD), polycystic dysplasia, glomeruli cystic raum, Bardet-Biedl, beckwith_wiedemann, Ivemark, Jeune, juvenile nephropathy, Von Hippel-Lindau kab mob thiab qog hlwv, thiab lwm yam kab mob. Cov qauv caj ces, kev kwv yees, thiab kev nthuav qhia ntawm cov kab mob no sib txawv, ua qhov kev kuaj mob kom raug yog qhov tseem ceeb rau kev tswj kom raug thiab kev tawm tswv yim txog caj ces. Kev nce qib tsis ntev los no tau pom ntau cov noob caj noob ces cuam tshuam nrog PKD, yog li ua rau muaj kev sib tw rau kev txheeb xyuas kom raug.
Case report
Ib tug poj niam muaj hnub nyoog 23-xyoo, nyob hauv ib cheeb tsam, nthuav tawm mus rau lub tsev kho mob obstetric nrog 36 lub lis piam ntawm cev xeeb tub thiab fetal poob. Nws yog gestation 2, 1st trimester, nchuav menyuam 1 ntawm 28 lub lis piam gestation; - tsis yog-consanguineous sib yuav. Nws tau mus kuaj plaub zaug ntawm lub tsev kho mob nyob ze, thiab peb qhov kev kuaj mob antenatal ntawm lub lis piam 12, 18, thiab 24, uas pom tau tias tus me nyuam hauv plab loj hlob zoo li qub thiab muaj cov kua dej amniotic txaus, tab sis qhov kev ntsuam xyuas zaum kawg pom tias cov kua dej amniotic tsawg. Txwv tsis pub, nws lub sij hawm prenatal yog qhov tsis zoo. Tsis muaj keeb kwm muaj mob, noj tshuaj, lossis ua npaws. Muaj keeb kwm yav dhau los ntawm kev tuag intrauterine ntawm 28 lub lis piam vim yog plab hnyuv me. Tus neeg mob yog los ntawm ib cheeb tsam nyob deb nroog thiab tsis muaj ntaub ntawv yug. Nws tsis muaj kev tshawb fawb txog caj ces rau kev nchuav menyuam hauv plab los yog kev qhia txog caj ces rau kev xeeb tub yav tom ntej. Nws tau nthuav tawm rau tus kws kho menyuam yaus hauv ib lub nroog hauv nroog yws yws ntawm fetal poob ntawm fetal txav thiab ultrasound (USG) pom qhov kev tuag ntawm tus menyuam hauv plab. Vim nws muaj ntau yam nchuav menyuam, tus me nyuam hauv plab tau raug xa mus rau peb lub chaw kuaj mob hauv 10 feem pua ntxhiab tsw buffered formalin rau fetal autopsy thiab me ntsis ntawm cov ntaub so ntswg tau coj mus rau microarray. Cov keeb kwm kho mob saum toj no tau muab los ntawm tus kws kho obstetrician. Ib tsev neeg kev tshuaj ntsuam genealogy tsis tau ua los ntawm tus kws kho mob thiab yog li ntawd tsis tau muab rau peb. Vim tus neeg mob tsis muaj kev koom tes, tsis tuaj yeem tshawb xyuas ntxiv.
Standardized Cistanche
Kev tshawb pom ntawm lub cev
Kev kuaj mob hauv lub cev tau ua tiav thiab tag nrho cov khoom nruab nrog raug kho hauv formalin thiab tom qab ntawd kuaj histopathologically, nrog cov ntaub so ntswg paraffin-embedded txiav mus rau 4 microns thickness thiab stained nrog cov pa hematoxylin thiab eosin stain (H&E). Qhov no yog poj niam fetus hnyav 3 kg thiab 43 cm ntev; qhov ntsuas anthropometric ntawm tus menyuam hauv plab yog sib npaug rau 36 lub lis piam ntawm lub hnub nyoog gestational. Lub fetus muaj ib tug luv luv, dav, bulbous qhov ntswg thiab ib tug tuab daim di ncauj. Tsis pom muaj lwm yam txawv txav txawv txav tseem ceeb. Internal kuaj pom cysts nyob rau hauv ntau lub cev. Cov kab mob siab tau nthuav tawm ntau lub hlwv ntawm 0 75 - 1 cm nyob rau hauv txoj kab uas hla uas muaj cov kua dej ntshiab, zoo ib yam nrog kev kuaj mob polycystic daim siab. Kev kuaj xyuas microscopic tau qhia ntau qhov chaw cystic interstitial nrog ib lub voj voos hauv qee qhov chaw (Daim duab 1a, b).
Daim duab 1a.Gross tsos qhia lub siab nrog ntau lub hlwv ntawm qhov sib txawv; b. microscopic low-power saib nrog ib nrab autolyzed ib txwm hepatic parenchyma thiab cov hlwv uas nyob ib sab ib nrab kab los ntawm cuboidal epithelium (H&E, 100 ×)
Kev ntsuam xyuas sab nraud ntawm lub raum pom ib feem ntawm kev saib xyuas ntawm txoj cai lub raum zoo li tus qauv thiab congestive hloov nyob rau hauv sab laug lub raum-shaped qauv. Ntau lub hlwv, 0 6-0.2 cm nyob rau hauv txoj kab uas hla, nyob rau hauv lub cortex thiab medulla, tau pom nyob rau hauv lub raum sab xis, thaum me me sab laug raum seem qhia 1- 0.3 cm-loj cysts npog tag nrho lub raum parenchyma. Cov kab mob microscopic tau lees paub tias muaj ntau tus glomerular cysts npaj los ntawm ib txheej ntawm cuboidal epithelium, zoo ib yam nrog ob sab polycystic raum kab mob (Daim duab 2a-d).
Daim duab 2a.Gross tsos uas qhia lub raum txoj cai nrog tswj reniform zoo thiab ntau hlwv nyob rau hauv lub raum parenchyma; b. tag nrho cov tsos uas qhia ntau cuam tshuam sab laug lub raum nrog poob ntawm reniform zoo thiab ntau cov hlwv piv rau sab xis; c, d low-power microscopy uas qhia lub raum parenchyma ib txwm nrog pawg glomeruli thiab ob peb hlwv kab los ntawm ib txheej ntawm cuboidal epithelium (H&E, 100 ×)
Kev kuaj mob qog nqaij hlav qog nqaij hlav qog nqaij hlav qog adrenal; Txawm li cas los xij, lub caj pas sab laug tau nthuav tawm cov qauv cystic loj uas npog cov ciam teb sab laug ntawm lub raum ntsuas 6 cm × 5 cm × 4.3 cm. Tom qab kev phais ntxiv, nws tau yooj yim cais tawm ntawm lub raum nto. Tshooj qhia tau hloov pauv tag nrho nyias-walled cyst uas muaj cov kua ntshiab thiab foci uas qhia tau hais tias compressed adrenal parenchyma li hypertrophic yellowish lug (Daim duab 3a, b). Ntau lub hlwv me me (0.2-0.3 cm) tau muab faib rau ntawm qhov chaw ntawm lub zais zis thiab pom cov hlwv me me uas muaj cov kab mob hypertrophied epithelium ntawm cov plasma membrane nam, thaum lub subsurface muscular txheej yog histologically li qub. Lub plawv, hlwb, thiab lub ntsws yog ib txwm nyob rau hauv tag nrho thiab histomorphology. Raws li cov kev tshawb pom no, kev kuaj mob zaum kawg ntawm ntau tus kab mob visceral polycystic tau tsim, raws li qhov kev tshawb pom tag nrho thiab morphological, tau lees paub los ntawm kev txiav txim siab, hauv qhov tsis tshua muaj tshwm sim ntawm qhov mob hnyav thiab ntxov ntawm cov kab mob polycystic raum.
Fig. 3ib. Tag nrho cov kev tshawb pom ntawm sab laug adrenal qhia txog kev txiav qhib, nyias-walled, uninoculated cyst nrog fattened yellowish cheeb tsam ntawm compressed ib txwm adrenal parenchyma ( xub); b. Tsis tshua muaj hwj chim microscopy qhia ib feem ntawm primitive adrenal parenchyma nrog cov kab mob cystic uas nyob ib sab lined los ntawm fattened cuboidal epithelium (H&E, 100 ×)
Kev tshuaj xyuas Chromosome microarray (CMA) tau ua tiav siv Affymetrix CytoScan 750K arrays ntawm tus menyuam hauv plab cov ntaub so ntswg thiab fetal feem ntawm cov placenta xa los ntawm saline-soaked gauze slices. Cov ntaub ntawv tau txheeb xyuas siv Chromosome Analysis Suite. Kev tsom xam yog raws li tib neeg siv genome (GRCh37 / hg 19). Tsis muaj qhov pom tseeb thaj tsam ntawm kev hloov pauv purity lossis rov ua dua-nruab nrab ntev txuas purity stretches tau kuaj pom hauv cov qauv.
Kev sib tham
Kev kho mob txiav tawm ntawm cev xeeb tub feem ntau pom zoo nyob rau hauv cov ntaub ntawv txheeb xyuas los ntawm USG los yog kev tshawb fawb caj ces uas tsis ua raws li qhov tseem ceeb tsis txaus ntseeg. Nyob rau hauv cov ntaub ntawv no, ib tug autopsy yuav pab kom mus txog qhov tseeb kev kuaj mob ntawm qhov txawv txav thiab tseem yuav pab txiav txim seb qhov tseeb ntawm lub ultrasound xeem. Fetal autopsies ntxiv cov ntaub ntawv tseem ceeb thiab hloov qhov kev pheej hmoo ntawm kev rov tshwm sim hauv 2.3 feem pua ntawm cov neeg mob. Piv txwv li, ib rooj plaub nrog ib daim ntawv qhia txog ultrasound ntawm autosomal recessive polycystic raum kab mob tau raug txiav tawm thiab ib qho kev txiav txim siab ntawm lub zais zis qhov hluav taws xob cuam tshuam nrog posterior urethral li qub thiab theem nrab cystic hloov nyob rau hauv ob lub raum. Ntawm no, ob kab mob muaj cov qauv qub qub sib txawv thiab tsis tshua muaj kev pheej hmoo ntawm kev rov tshwm sim tsawg dua piv rau polycystic raum uas muaj 25 feem pua ntawm qhov rov tshwm sim.
Polycystic raum kab mob
Kev nthuav qhia ntau ntawm PKD suav nrog ntau lub raum hlwv thiab lub raum loj thaum menyuam yaus lossis hluas. Raws li qhov no, nws tau muab faib ua plaub yam sib txawv: 1. Porter's Syndrome I-ARPKD; 2. cystic dysplasia ntawm lub raum; 3. ADPKD thiab 4. hydronephrosis lossis lub raum capsule. Qhov sib txawv ntawm kev soj ntsuam thiab kev nthuav qhia pathological pab peb piav qhia txog hom kab mob. Cov kua dej uas muaj focal cysts tshwm sim vim muaj kev tsis sib haum xeeb ntawm ntau txoj hauv kev, xws li kev loj hlob ntawm tes, qhov txawv txav ntawm epithelial polarity, apoptosis, thiab kua dej tso tawm, ua rau cov tsos mob xws li mob plab, hematuria, plawv plawv, thiab lub raum calculi. Cov kab mob urinary rov tshwm sim nrog qhov tshwm sim ntawm lub raum tsis ua haujlwm tshwm sim tom qab lub neej ntawm ADPKD, sau tubular shuttle dilation, loj thiab fibrotic portal cheeb tsam, bile duct hyperplasia, thiab portal vein ceg hypoplasia ua rau portal hypertension hauv ARPKD nrog rau thaum yau thaum yau kawg. Lub raum kab mob thiab congenital hepatic fibrosis piv rau echogenic lub raum loj pom nyob rau hauv utero los yog lub sij hawm neonatal [13]. Nyob ntawm hom kab mob, kev kuaj caj ces yuav txawv. Kev nthuav qhia kho mob thiab spectrum yuav pab peb ua qhov kev kuaj mob. Qhov no ntxiv rau qhov tseem ceeb ntawm kev faib cov kab mob kom raug rau kev kho mob kom tsim nyog.
Herba Cistanche
Genetics ntawm PKD
PKD1 noob ntawm caj npab luv ntawm chromosome 16 (4304 amino acids) thiab PKD2 noob ntawm caj npab ntev ntawm chromosome 4 (969 amino acids) tau txuam nrog ADPKD hauv 85 feem pua thiab 15 feem pua ntawm cov neeg mob, feem. Ntxiv nrog rau hemizygous variants ntawm PKD1 thiab PKD2, ARPKD kuj tseem cuam tshuam nrog ob npaug allelic variants ntawm PKHD1 [13]. Kev tshem tawm lossis kev puas tsuaj ntawm cov khoom lag luam protein ntawm PKD1 thiab PKD2 noob, polycystin-1 (PC-1) thiab polycystin-2 (PC-2), tau pom tias muaj feem cuam tshuam nrog rau lub raum. cysts. PC-1 thiab PC-2, uas yog nyob rau hauv lub raum tubules, yog lub luag hauj lwm rau kev sib txawv, tu, thiab kho lub raum tubular hlwb. Nws kuj tseem koom nrog hauv kev thauj mus los ntawm calcium intracellular thiab cell cycle regulation.PC-1 yog qhov loj integrin txiav txim siab ntau lub cev phenotype thiab muaj nyob rau hauv cilia thiab plasma daim nyias nyias ntawm txhua qhov chaw cyst (ob raum, siab, pancreas) thiab kuj hauv PKD rooj plaub; lawv tau pom tias overexpressed. Cov qauv caj ces ntawm ADPKD yog ze li ntawm 100 feem pua ntawm cov kab mob epistatic, raws li keeb kwm yav dhau los ntawm kev tuag ntawm niam txiv hauv tsev menyuam yog cuam tshuam nrog tsev neeg ADPKD, tab sis tsis tuaj yeem lees paub vim niam txiv tsis pom zoo.
Ntshav siab yog qhov tshwm sim ntxov ntawm PKD, tshwm sim hauv 50-62 feem pua ntawm cov neeg mob uas lub raum ua haujlwm tsis zoo thiab hauv 100 feem pua ntawm cov neeg mob lub raum tsis ua haujlwm. Kev cuam tshuam ntawm ductal phaj reconstruction thaum lub sij hawm lig embryonic txoj kev loj hlob yog lub luag hauj lwm rau tus mob no. Qhov pib ntawm cysts pib nyob rau hauv lub embryonic theem ntawm lub raum txoj kev loj hlob thiab loj hlob mus rau cov neeg laus, b raws li pom tseeb los ntawm peb cov ntaub ntawv. Qhov pib ntxov ntawm tus kab mob no yog tshwm sim los ntawm kev sib koom ua ke ntawm qhov sib txawv lossis tsis tiav penetrant allele ntawm PKD1 noob nrog mutant 1. PKD ua rau lub raum poob nws cov duab, qhov loj, thiab qhov hnyav, uas yog qhov ua rau lub raum tsis zoo. ua tsis tiav. Muaj ntau cov hlwv ntawm lub raum cortex lossis medulla yog qhov qhia tau tias muaj mob hnyav ntawm PKD, uas yog raws li peb daim ntawv tshaj tawm.
Lub raum sab laug feem ntau cuam tshuam rau hauv cov mob polycystic piv rau lub raum sab xis, uas yog raws li peb qhov kev tshawb pom.PKD yog ib qho systemic ciliopathy uas tuaj yeem ua rau lub raum thiab lub raum ntxiv, thiab daim siab, pancreas, spleen, seminal vesicles, testes lossis zes qe menyuam. thiab arachnoid cysts muaj nyob hauv kwv yees li 5 feem pua ntawm cov neeg laus. Txawm li cas los xij, qhov muaj cov kab mob hauv lub raum tsis tshua muaj tshwm sim hauv cov neeg mob hluas thiab yog li ntawd peb cov ntaub ntawv tsis tshua muaj. Hepatic cysts yog qhov tshwm sim ntau tshaj plaws ntawm lub raum ntawm PKD, qee zaum tseem ceeb tshaj qhov tshwm sim ntxiv rau lub raum. Tus kab mob polycystic siab (PLD) feem ntau yog asymptomatic, tab sis cov neeg mob tau tshaj tawm nrog cov teeb meem kho mob vim hepatomegaly.
Qhov tshwm sim ntawm cov qog adrenal cais nyob rau hauv cov neeg mob autopsy yog 0.06-0.18 feem pua . Cov no yog ib pawg heterogeneous ntawm qhov txhab, feem ntau unilateral, zoo ib yam li peb cov ntaub ntawv, nrog cysts nyob rau hauv sab laug adrenal cheeb tsam. Lawv qhov tseem ceeb tshaj plaws ntawm cov poj niam ntau dua li cov txiv neej (3: 1), uas yog raws li peb qhov xwm txheej. Feem ntau, nws cov etiology tsis paub, tab sis qee zaum, nws cuam tshuam nrog intracapsular hemorrhage lossis cystic deterioration ntawm thawj cov qog adrenal thiab vascular. Nws yog asymptomatic feem ntau thiab yuav tsis raug kuaj pom.
Bergmann thiab al qhia yim yim tsev neeg uas muaj ntau yam fetus poob vim PKD1 noob hloov. Qee qhov ntawm peb qhov kev tshawb pom zoo sib xws nrog nws txoj kev tshawb fawb, tab sis muaj cov kab mob sib kis tsis tau pom nyob rau hauv ib qho ntawm nws cov ntawv tshaj tawm txog kev tuag. Yog li, muaj ntau yam kab mob hauv lub cev nrog PKD hauv peb cov ntaub ntawv qhia tias muaj lwm cov noob koom nrog hauv txoj kev loj hlob ntawm embryonic ua ke nrog PKD1 noob. Lub xub ntiag ntawm aneurysms thiab kab mob hauv lub plawv tau cuam tshuam nrog PKD nrog qhov ntau ntawm 8 feem pua thiab 26 feem pua , feem.
Txoj kev loj hlob ntawm CMA tau coj mus rau 12-15 feem pua nce hauv kev tshawb nrhiav cov kab mob caj ces piv rau cov qauv siv. Hauv cov qauv cyst ntau lub cev no, tsis muaj thaj chaw tseem ceeb ntawm cov zygotes dawb huv lossis rov ua dua-nruab nrab ntev txuas nrog cov zygotes, uas tseem tsis tau paub thiab qhia txog kev koom tes ntawm cov tsis paub cov kab mob sib txawv lossis kev cuam tshuam ntawm epigenetic.
Hauv peb qhov xwm txheej, tsis muaj qhov txawv txav digital, lossis mob plawv, CNS, lossis kev ua pa tsis zoo. Yog li, Meckel's, Di George, VACTERL abnormalities, BNAR, BOR, thiab CHARGE syndromes raug cais tawm. Xav txog cov cim qhia, cov tsos mob, thiab kev nthuav qhia, peb ntseeg tias qhov no yog qhov tshwm sim ntawm cov kab mob polycystic raum thaum ntxov thiab hnyav ua ke nrog ntau cov kab mob hauv nruab nrog cev, suav nrog cov qog adrenal, ntxiv rau nws qhov tsis tshua muaj. Lub xub ntiag ntawm noob caj noob ces tsis tuaj yeem txiav txim siab, tab sis nws qhov kev txheeb xyuas yog qhov tseem ceeb los txiav txim qhov keeb kwm thiab kev pheej hmoo ntawm kev rov tshwm sim.
Xaus
Daim ntawv tshaj tawm rooj plaub no yuav hais ntxiv txog qhov tseem ceeb ntawm fetal autopsy nyob rau hauv qhov teeb meem ntawm cov keeb kwm tsis tiav obstetric. Feem ntau, nws tseem muab cov txiaj ntsig ntsig txog keeb kwm thiab kev pheej hmoo ntawm kev rov qab los ntawm kev xeeb tub yav tom ntej. Kev cob qhia tsim nyog thiab kev sib tham txog caj ces raws li cov txheeb ze yuav tsum tau muab rau cov neeg hauv tsev neeg.
Cistanche tubulosa
Yuav ua li cas txhim kho polycystic raum kab mob nrog Cistanche extract?
Polycystic raum kab mob (PKD) yog ib yam kab mob caj ces uas ua rau kev loj hlob ntawm cov hlwv hauv ob lub raum, ua rau lub raum tsis zoo thiab ua rau lub raum tsis ua haujlwm. Tam sim no, tsis muaj kev kho rau PKD, tab sis cov khoom siv ntuj xws li Cistanche extract tau pom cov lus cog tseg hauv kev txhim kho tus mob.
Cistanche extract yog muab los ntawm Cistanche cog, uas paub txog nws cov khoom siv tshuaj hauv Suav tshuaj. Nws muaj ntau yam bioactive tebchaw xws li echinacoside thiab Acteoside, uas tau pom tias muaj ntau yam tshuaj rau lub cev, suav nrog antioxidant, tiv thaiv kab mob, thiab kev tiv thaiv kab mob.
Cov kev tshawb fawb tau pom tias Cistanche extract tuaj yeem txhim kho lub raum ua haujlwm hauv cov neeg mob PKD. Ib txoj kev tshawb fawb pom tau tias cov nas tsuag nrog PKD uas tau muab Cistanche extract tau txo qis cov cyst loj hlob thiab txhim kho lub raum ua haujlwm piv rau cov nas uas tsis tau txais cov extract. Lwm txoj kev tshawb nrhiav pom tias kev tswj hwm Cistanche extract rau cov neeg mob nrog PKD ua rau txo qis hauv cyst loj thiab txhim kho lub raum ua haujlwm.
Cistanche extract kuj tseem tuaj yeem pab txo qis oxidative kev nyuaj siab, uas ua lub luag haujlwm hauv kev loj hlob ntawm PKD. Cov khoom antioxidant ntawm Cistanche extract tuaj yeem pab tiv thaiv kev puas tsuaj rau lub raum los ntawm cov dawb radicals thiab lwm yam khoom tsis zoo.
Hauv kev xaus, Cistanche extract tej zaum yuav yog ib qho kev cog lus ntuj ntxiv rau cov tib neeg nrog PKD tab tom nrhiav kev txhim kho lawv lub raum ua haujlwm. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tau sab laj nrog tus kws kho mob ua ntej noj cov tshuaj tshiab, vim tias lawv yuav cuam tshuam nrog cov tshuaj los yog muaj kev phiv.
Cov ntaub ntawv
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K. Indumathi1;G. Bhavani1; K. Sudha2; G. Srinivasaraman2; R. Manjunathan1.
1 Department of Pathology, Anderson Labs and Diagnostics, Chennai, Tamil Nadu 600084, India
2 Department of Radiology, Anderson Labs and Diagnostics, Chennai, Tamil Nadu 600084, India
