Phenethyl Cawv Glycosides hauv Cistanche Deserticola, Lawv Mechanism Ntawm Kev Ua Thiab Kev Tswj Xyuas Zoo
Jul 04, 2023
Cistanche deserticola, ib txwm suav tshuaj, yog lub cev qhuav dej nrog cov nplooj scaly ntawm Cistanche deserticola los yog Cistanche tubulosa, ib tsob nroj ntawm Orobanchaceae. Nws tseem hu ua Da Yun. Nws yog ib qho tshuaj suav tshuaj rau tonifying lub raum thiab yang, thiab thawj zaug luam tawm hauv Shennong Ben Cao Jing. Nws muaj cov teebmeem ntawm tonifying lub raum thiab yang, txhim kho cov ntshav essence, thiab soothing cov hnyuv thiab plab hnyuv. Qhia txog kev kho tus txiv neej impotence, poj niam infertility, los ntshav, thiab cem quav, nws yog hu ua "desert ginseng".
Phenylethanol glycoside yog lub luag haujlwm tseem ceeb ntawm Cistanche deserticola
Nyem qhov no mus saib Cistanche cov khoom
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Txij li thaum xyoo 1970, cov kws tshawb fawb hauv tsev thiab txawv teb chaws tau pib kawm txog cov tshuaj lom neeg thiab cov tshuaj ua haujlwm ntawm Cistanche cov nroj tsuag. Txog tam sim no, ze li ntawm ib puas yam tshuaj lom neeg thiab cov kab mob tau raug cais tawm thiab txheeb xyuas los ntawm Cistanche deserticola, ntawm cov tshuaj Phenethyl cawv glycosides muaj cov ntsiab lus siab tshaj plaws, uas yog ib qho ntawm cov khoom tseem ceeb ntawm Cistanche cov nroj tsuag, thiab tseem yog ib qho kev qhia rau kev txheeb xyuas. thiab kev txiav txim siab cov ntsiab lus raws li cov khoom "Cistanche deserticola" hauv Suav Pharmacopoeia. Los ntawm kev tshawb fawb tob tob los ntawm Tu Pengfei pab pawg ntawm Peking University, txog rau tam sim no, ze li 40 hom Phenethyl cawv glycosides tau muab cais tawm kom meej thiab txheeb xyuas. Tsis tas li ntawd, tag nrho Phenethyl cawv glycosides los ntawm Cistanche tubulosa kuj tau tsim, nrog echinacin thiab Verbascum thapsus glycosides ua cov khoom tseem ceeb.
Cov tshuaj tseem ceeb ntawm Cistanche deserticola
Phenethyl cawv glycosides (PHGs) yog ib hom glycosides tsim los ntawm kev sib xyaw ntawm Phenethyl cawv aglycones thiab pawg suab thaj. Feem ntau ntawm Phenethyl cawv glycosides hauv Cistanche deserticola muaj cov qauv dav dav (saib daim duab 1), thiab lawv cov suab thaj feem ntau yog cov piam thaj thiab Rhamnose; Lub hauv paus qab zib txuas ncaj qha mus rau aglycone yog qabzib; Rhamnose tau txuas rau 3 txoj haujlwm ntawm cov piam thaj hauv nruab nrab tsuas yog monosaccharide; Cov piam thaj thib ob hauv triglycoside feem ntau txuas nrog 6 txoj haujlwm ntawm cov piam thaj hauv nruab nrab; Ntawm txoj haujlwm 4 lossis 6 ntawm cov piam thaj hauv nruab nrab, nws feem ntau tsim cov esters nrog phenylacryloyl pawg xws li caffeioyl, ferulic, lossis coumarinyl.
Suab puam ginseng
Ntau qhov kev tshawb fawb tau pom tias Phenethyl cawv glycosides ua rau qib cellular ntawm lub cev, thiab cov tshuaj pharmacodynamic tseem ceeb yog ua los ntawm kev tswj hwm cov txheej txheem ntawm tes. Cov tshuaj pharmacological tseem ceeb suav nrog kev tiv thaiv kev laus, antioxidant, kev tiv thaiv ntawm tes, kev tiv thaiv kab mob, lub raum tonifying thiab yang ntxiv dag zog. Piv txwv li, Phenethyl cawv glycoside tuaj yeem cuam tshuam qhov txo qis ntawm cov ntshav qab zib thiab lub hlwb Superoxide dismutase (SOD) kev ua, txo daim siab thiab cov ntshav MDA, thiab pab lub cev ua lub luag haujlwm ntawm kev tiv thaiv oxidation thiab tiv thaiv kev laus.
Cov teebmeem ntawm Cistanche-Resist qaug zog
Tonifying lub raum thiab ntxiv dag zog rau yang feem ntau ua haujlwm nyob rau hauv ob txoj kev: ua ntej, txhim kho lub hypothalamic pituitary adrenal muaj nuj nqi, txhawb kev tso tawm ntawm cov neurotransmitters thiab cov tshuaj hormones hauv lub cev, thiab ua kom muaj kev sib deev muaj siab; Qhov thib ob, nws muaj cov nyhuv ntawm kev qaug zog thiab txhim kho lub cev ua haujlwm. Phenethyl cawv glycosides kuj muaj lub luag haujlwm ntawm kev tiv thaiv cov paj hlwb thiab cov hlwb myocardial, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv qog, txhim kho kev nco thiab kev ua haujlwm ntawm kev sib deev. Phenethyl cawv glycosides yog lub active Cheebtsam ntawm Cistanche deserticola uas ua si lub luag hauj lwm neuroprotective.
Cistanche deserticola kev sim
Tam sim no, ntau tus kws tshawb fawb tswj cov ntsiab lus ntawm Phenethyl cawv glycosides hauv Cistanche deserticola tsuas yog los ntawm ultraviolet spectrophotometric thiab High-performance kua chromatography, thiab cov ntsiab lus tseem ceeb yog echinacea, guanosine A, Verbascum thapsus glycoside, thiab isostamen glycoside.
