Overview Of Treatment Of Vascular Dementia With Warming Yang Txoj Kev

Vascular dementia(VaD)yog ib hom kab mob cerebrovascular uas nquag tshwm sim hauv cov neeg laus thiab cov neeg laus, nrog rau kev kawm thiab kev nco tsis ua haujlwm raws li kev kho mob tseem ceeb, suav nrog kab mob ischemic cerebrovascular, hemorrhagic cerebrovascular kab mob, thiab dementia tshwm sim los ntawm mob hnyav lossis mob hypoxic cerebrovascular kab mob.. Raws li cov ntaub ntawv cuam tshuam, qhov ntau ntawm VaD hauv Suav teb yog 1.1 feem pua ​​​​rau 3.0 feem pua, cuam tshuam rau lub neej zoo ntawm cov neeg mob. Nrog rau qhov tshwm sim ntawm lub ntiaj teb kev laus era, qhov tshwm sim ntawm VaD tau nce. Ntawm ib sab, kev tiv thaiv VaD tuaj yeem txhim kho lub neej zoo ntawm cov neeg laus, txo lub nra ntawm tsev neeg thiab tib neeg, thiab ntawm qhov tod tes, nws tuaj yeem ua tiav "kev laus noj qab haus huv" uas tau thov los ntawm World Health Organization. VaD belongs rau qeb ntawm "dementia" hauv cov tshuaj suav tshuaj, thiab nws qhov tshwm sim feem ntau cuam tshuam nrog cov yam ntxwv xws li phlegm, ntshav stasis, turbidity, toxicity, thiab deficiency. Kev kho mob feem ntau yog ua raws li cov txheej txheem ntawm enriching essence thiab txawj ntse, tonifying qi thiab ntshav, txhawb cov ntshav ncig thiab daws stasis, daws phlegm, thiab qhib lub orifices. Nyob rau hauv xyoo tas los no, nrog kev nce ntawm Fuyang tsev kawm ntawv hauv kev kawm ntawm cov tshuaj suav tshuaj, qee qhov kev ua tiav tau ua tiav hauv kev kho VaD siv txoj kev ua kom sov yang. Cov hauv qab no yog cov ntsiab lus.

Suav tshuaj ntsuab cistanche- Tiv thaiv Alzheimer's Disease khoom

TCM kev kho mob

VaD nyob rau hauv lub hlwb thiab hauv paus hauv tsib lub hauv nruab nrog cev. Tus kab mob no tshwm sim los ntawm qhov tsis txaus thiab ntau dhau ntawm keeb kwm thiab muaj ntau dua hauv cov neeg mob laus. Nws qhov tsis txaus yog vim qhov tsis txaus ntawm yang thiab qi.Yog li, kev xaiv tshuaj kho mob thiab tshuaj yuav tsum tau ua raws li kev cai lij choj ua kom sov yang, ntxiv los ntawm cov txheej txheem xws li sau cov ntsiab lus thiab cov pob txha, tonifying qi thiab ntshav, txhawb cov ntshav ncig thiab daws qhov tsis zoo, thiab tshem tawm cov hluav taws thiab tshem tawm phlegm raws li cov tsos mob sib txawv, uas tuaj yeem ua tau. ua tiav cov txiaj ntsig zoo. Rosa et al. [9] ntseeg hais tias cov neeg niaj hnub no feem ntau yog tus cwj pwm los ntawm yang deficiency vim muaj cov yam ntxwv xws li kev ua neej, yog li VaD feem ntau tshwm sim los ntawm yang deficiency, muab cov tswv yim tshiab thiab cov hau kev rau kev kho mob thiab kev sib txawv ntawm cov tsos mob thiab cov cim ntawm VaD. Zhang Ruijie (10) ntseeg li ntawdua kom sov yang thiab kho phlegm yog tus yuam sij rau kev kho mob ntawm VaD. Nws tau muab faib ua 60 tus neeg mob nrog VaD ua ob pawg. Pab pawg tswj hwm tau noj cov tshuaj nimodipine, 40 mg txhua zaus, peb zaug ib hnub; Pab pawg kho mob coj Wenyang Huatan Decoction (qhuav qhiav, Morinda Officinalis, osmanthus cassia "Branches, npaj Spinelli ternata, Acorus calamus, Poria cocos (15g txhua), ua tiav aconite (decocted ua ntej) 12g, tangerine tev, npaj nan xing, ginseng. txhua, thiab ci licorice 6g txhua), nrog rau lub sijhawm kho mob 2- hli. Tom qab 6 lub hlis ntawm kev kho mob, ADL cov qhab nia, MMSE cov qhab nia, thiab tag nrho cov txiaj ntsig zoo ntawm ob pawg tau muab piv rau. "Cov txiaj ntsig tau pom tias tom qab kev kho mob, qhov qhab nia ALD hauv pab pawg kho mob poob qis dua piv nrog qhov ua ntej kho thiab tom qab kev kho mob hauv pawg tswj hwm (P<0.05), while the MMSE score increased compared with that before treatment and after treatment in the control group (P<0.01). The total effective rate in the treatment group was significantly better than that in the control group (P<0.05), indicating that Wenyang Huatan Decoction can effectively improve the daily living ability of patients, improve their cognitive function, and improve their quality of life. Wang Qizhi et al. [11] believe that the formation of VaD is mainly related to the weakness of the lung function, which leads to insufficient intake of clear qi in the human body, resulting in passive gasification of the body, inability to replenish the brain due to qi deficiency, accumulation of turbid qi in the body, interaction of turbid qi and blood as blood stasis, and turbid qi ascending with blood in the brain and stagnation of the brain meridians. They also use the "Wenfei Jiangzhuo Tang Tang Tang Tang Tang Decoction", which was prepared by Professor Tang Nong of the Fuyang School and consists of prepared aconite (decocted first) 30g, ginseng 15g, roasted licorice, dried ginger, wine rhubarb Tian Sanqi (10g each) is used to treat patients with VaD, supporting the body's yang qi, and eliminating phlegm, dampness, and cold. Results: There were 16 cases with significant effect, 12 cases with effective effect, and 2 cases with ineffective effect. The clinical efficacy was 93.3%, indicating that Wenfei Jiangzhuo Decoction can achieve certain efficacy in the treatment of VaD. Tang Nong et al. [12] believe that the etiology and pathogenesis of VaD are mainly qi stagnation, phlegm turbidity, and blood stasis, and their formation is rooted in the deficiency of yang in the five zang organs. Based on this understanding, 44 patients with atherosclerotic VaD were treated with a self-developed Wuzang Wenyang Huayu Decoction (30g monkshood, 15g epimedium, ginger, morinda officinalis, cassia twig, Spinelli ternata, notoginseng, Acorus tatarinowii, ginseng, and 6g rhubarb), with a total effective rate of 86.36%. Qhov kev kho no tuaj yeem txhim kho tus neeg mob lub neej txhua hnub muaj peev xwm thiab kev ua haujlwm tsis zoo ntawm lub paj hlwb.

Cistanche hmoov cov txiaj ntsig kev noj qab haus huv- Tiv thaiv Alzheimer's Disease khoom

Integrated tsoos suav thiab Western tshuaj kho

Kev kho mob ntawm VaD nrog Wenyang Cov Ntawv Tshuaj ua ke nrog cov tshuaj Western tuaj yeem ua si lawv cov txiaj ntsig zoo thiab ua tiav cov txiaj ntsig ntxiv, yog li txhim kho kev kho mob zoo. Lv Liv et al. [13] faib cov neeg laus uas muaj VaD (yam tsis muaj peev xwm) ua ob pawg. Pab pawg tswj hwm tau txais kev kho mob yooj yim thiab muab tshuaj rau qhov ncauj butylphthalide capsules. Cov pab pawg tshawb fawb tau muab Wenpi Tongluo Kaiqiao Decoction (30g astragalus cag, 10g txhua ntawm Yizhiren, Sanqi, Shichangpu, Polygonum multiflorum, Gynostemma pentaphyllum, Npaj aconite, Eucommia ulmoides, 6g cinnamon, 15g.cistanche deserticola) raws li pawg tswj hwm. Tom qab peb qhov kev kho mob sib law liag, qhov yooj yim ntawm kev ntsuam xyuas kev puas siab puas ntsws ntsuas ntsuas MMSE, HDS, thiab MoCA tau siv BI cov qhab nia tau siv los ntsuas cov neeg mob kev paub txog kev ua haujlwm thiab kev ua ub no ntawm kev ua neej nyob txhua hnub, sib piv ntau yam kev soj ntsuam kev soj ntsuam, thiab sau qhov tshwm sim ntawm qhov tshwm sim tsis zoo. . Cov txiaj ntsig tau pom tias cov tsos mob tshwm sim hauv pawg tshawb fawb tau txhim kho zoo dua piv rau yav dhau los, thiab tau zoo dua rau pawg tswj hwm (P<0.05). The incidence of adverse reactions in the study group was lower than that in the control group. This indicates that this prescription combined with butylphthalide can effectively improve the cognitive function and daily living ability of elderly patients with VaD (yang deficiency type). Zhuang He et al. [14] studied the improvement of cognitive function and daily living ability of VaD patients with integrated traditional Chinese and Western medicine. They divided VaD patients into two groups. The control group was treated with Liuwei Dihuang Decoction alone (30g bovine spinal cord, 20g tortoiseshell, 12g Poria cocos, and ginseng each, 12g yam, rhizoma polygonal, and Acorus tatarinowii each, 6g alisma orientalis, 9g peony bark, 10g gastrodia elata, Fructus oxyphylli, and cistanche deserticola ma, 5g aconite, thiab 3g cassia twig txhua), Cov pab pawg ua ke tau muab buflomedil hauv qhov ncauj los ntawm pawg tswj hwm rau 2 lub hlis. MMSE thiab BI cov qhab nia tau siv nyob rau hauv thawj thiab thib ob lub hlis ntawm kev kho mob, feem. Cov txiaj ntsig tau pom tias MMSE thiab BI cov qhab nia ntawm pab pawg kho mob ntawm ob lub sijhawm no tau siab dua cov pab pawg tswj hwm (P. Huang Xunfu li al. [15] kho tus kab mob nrog cov tshuaj suav tshuaj suav thiab Western, thaum lub Pab pawg tswj hwm tau kho nrog cov tshuaj sab hnub poob.Cov kev soj ntsuam pab pawg tau kho nrog hloov kho Dihuang Yinzi Decoction ntawm lub hauv paus no, kev kho mob yog 3 lub hlis, thiab cov qhab nia ntawm ADL thiab HDS tau muab piv.

Superman tshuaj ntsuab cistanche-Prevent Alzheimer's Disease khoom

Nyem qhov no mus saib Cistanche Txhim Kho Kev Nco thiab Tiv Thaiv Alzheimer's Disease cov khoom

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Cov txiaj ntsig tau pom tias tag nrho cov txiaj ntsig zoo ntawm kev coj tus cwj pwm muaj peev xwm hauv pab pawg soj ntsuam tom qab kho tau ntau dua li hauv pawg tswj hwm (P＜{{0}}}05). Tom qab kev kho mob, qhov qhab nia ADL hauv pawg soj ntsuam tau siab dua qhov ua ntej kev kho mob thiab hauv pawg tswj hwm (P＜0.05), thiab cov qhab nia HDS tau qis dua qhov ua ntej kev kho mob thiab hauv pawg tswj hwm (P＜0.05). Yog li ntawd, nws ntseeg tau tias kev siv tshuaj suav tshuaj suav nrog Western tshuaj tuaj yeem txhim kho kev txawj ntse thiab muaj peev xwm ua neej nyob niaj hnub ntawm Va cov neeg mob, uas tsim nyog ntawm kev kho mob.

Mechanism ntawm kev ua

1) Ib daim ntawv tshuaj rau kom sov yang.

Nyob rau hauv xyoo tas los no, kev tshawb fawb yooj yim tau pom tias Sini Decoction, Shenfu Txhaj, Dipsacus, Epimedium,Cistanche deserticola, thiab lwm yam yang warming formulas muaj cov teebmeem neuroprotective tseem ceeb. Cov nyhuv neuroprotective ntawmCistanche deserticola tau raug lees paub, thiab nws cov txheej txheem tiv thaiv yog ze ze rau kev txhim kho lub peev xwm txhawm rau tshem tawm cov pa dawb radicals, txhim kho GSH-Px kev ua haujlwm, txo NOS synthesis, thiab txhim kho antioxidant muaj peev xwm. Qee qhov kev tshawb fawb tau lees paub tiasCistanche deserticolamuaj kev tiv thaiv ntawm hippocampal neurons raug mob los ntawm cerebral ischemia, thiab nws cov txheej txheem muaj feem cuam tshuam nrog kev tshem tawm cov pa dawb radicals, anti-neuronal apoptosis, thiab stabilizing intracellular calcium ions. Zhu Dan et al. [17] tau los ntawm Morris dej tshawb nrhiav kev coj cwj pwm uas txhaj tshuaj intraperitoneal ntawm 4 ml / (kg · d)Cistanche deserticolatuaj yeem nce tus naj npawb ntawm lub sijhawm VaD nas hla lub platform thiab txhim kho lawv txoj kev kawm thiab kev nco muaj peev xwm.

Cistanche ua dab tsi rau lub cev - Tiv thaiv Alzheimer's Disease cov khoom

2) Suav tshuaj ntsuab rau sov yang.

Suav tshuaj ntsuab xws li Dipsacus, Epimedium, thiab Cistanche deserticola thiab lawv cov extracts muaj qee yam kev tiv thaiv ntawm neurons.. Qee qhov kev tshawb fawb tau lees paub tias cov txheej txheem ntawm vascular puas tsuaj los ntawm VaD feem ntau cuam tshuam nrog kev tsim cov pa oxygen dawb radicals ntau tom qab cerebral ischemia thiab hypoxia, yog li ua rau cov hlab ntsha hauv lub hlwb puas, thaum Bcl -2 noob muaj cov nyhuv ntawm inhibiting cell apoptosis. Hong Ru et al. [18] pom nyob rau hauv kev sib tham txog kev tiv thaiv los ntawm Dipsacus extract ntawm kev kawm thiab kev nco muaj peev xwm thiab hippocampal neurons hauv VaD nas uas Dipsacus extract tuaj yeem ua rau kom muaj kev qhia ntawm Bcl -2 gene, txhim khu lub peev xwm los tshem tawm cov pa oxygen dawb radicals, txhim kho lub cev muaj peev xwm antioxidant, thiab muaj peev xwm tiv thaiv apoptosis. Nws muaj qee yam kev tiv thaiv ntawm neurons hauv cerebral ischemia thiab hypoxia nas, yog li txhim kho kev kawm thiab kev nco muaj peev xwm ntawm VaD nas. Xu Ruixia et al. [19] lees paub hauv lawv txoj kev tshawb fawb txog kev tiv thaiv ntawmCistanche deserticolantawm kev kawm thiab kev nco hauv cov nas uas nws cov txiaj ntsig neuroprotective cuam tshuam nrog nws lub peev xwm los nce SOD kev ua haujlwm, nce kev qhia ntawm ChAT thiab AChE, txo MDA cov ntsiab lus, thiab inhibit kev tsim cov lipid peroxides hauv cov neurons. Yang Bo et al. [20] tau kawm txog kev ua tau zoo ntawm tag nrho glycosides ntawmCistanche deserticolanyob rau hauv kev kho mob ntawm VaD cov neeg mob uas muaj me me mus rau nruab nrab kev paub tsis meej.Cov txiaj ntsig tau pom tias tag nrho glycosides ntawmCistanche deserticolatuaj yeem txhim kho kev txawj ntse, txo qhov degree ntawm dementia, thiab txhim kho lub peev xwm ntawm kev ua neej nyob niaj hnub hauv VaD cov neeg mob, uas muaj feem xyuam nrog cov yam ntxwv xws li kev tshem tawm ntau cov pa oxygen dawb radicals los ntawm tag nrho glycosides ntawm cistanche.

Suab puam nyob cistanche

Cov ntsiab lus

Hauv cov ntsiab lus, cov tshuaj suav tshuaj tau ua tiav qee yam hauv kev tiv thaiv thiab kho VaD. Lub tsev kawm ntawv kev kawm ntawm Fuyang siv "yang deficiency" raws li lub ntsiab lus tseem ceeb ntawm kev sib txawv ntawm cov tsos mob, thiab siv txoj kev ua kom sov yang los kho VaD, uas tau ua tiav qee yam kev ua tau zoo thiab txhawb kev nkag siab ntawm VaD. Txoj kev ua kom sov yang yuav coj cov tswv yim tshiab thiab kev cia siab dav rau kev kho VaD. Nyob rau hauv lub neej yav tom ntej, ntau tus qauv thiab kev tshawb fawb soj ntsuam kev tshawb fawb yuav tsum tau ua, thiab cov txiaj ntsig kev tshawb fawb yuav tsum tau siv rau kev kho mob kom cov tshuaj suav tshuaj kho mob tuaj yeem ua lub luag haujlwm ntau dua hauv kev kho cov neeg mob VaD.

siv

[1] Weng Yinghong, Huang Jianhong. Kev txhais thiab kev kuaj mob ntawm vascular dementia ［J］. Guangdong Medical Journal, 2010, 31 (14): 1881-1882

[2] Zhao Qinghan. Siv txoj kev xav ntawm ib Qi ncig los tshawb txog cov txheej txheem ntawm kev kho mob vascular dementia los ntawm lub ntsws ［ J］. Phau ntawv Journal of Guiyang College of Traditional Chinese Medicine, 2013, 35 (6): 51-53

[3] Jia Menghui, He Xiaohui, Tian Jianying. Kev Kho Mob Alzheimer's Disease los ntawm Yang Deficiency [J]. New Chinese Medicine, 2005, 37 (7): 80-81

[4] Lu Chaw. Cov lus qhuab qhia ntawm Fuyang. Beijing: Tuam Tshoj tsoos suav tshuaj Xovxwm, 2006: 47176189

[5] Xing Bin, Huang Li. Zhu Weiju: Kev Ntsuam Xyuas Ntawm Tsib Phau Ntawv Kho Mob. Beijing: Tuam Tshoj tsoos suav tshuaj Xovxwm, 2008: 169