Molecular Mechanisms Thiab Biomarkers Associated With Chemotherapy-Induced AKI Ⅲ
Aug 16, 2024
7. Cov lus xaus
Qhov xwm txheej tiag tiag ntawm AKI-txuas nrog nephrotoxicity tsis paub, thiab tsis muaj kev vam meej me ntsis hauv nws txoj kev kho thiab tiv thaiv. Qhov no yuav yog vim qhov sib txawv tseem ceeb hauv peb txoj kev paub txog lub raum teb cov txheej txheem rau AKI. Peb tsis ntev los no tau pom tias polyploidy ntawm TEC sawv cev rau yav dhau los tsis paub txog cov lus teb rau lub raum puas. Cov polyploid TEC no tau raug ntes nyob rau hauv G1 [54,215], qhia txog qhov kev xav zoo sib xws nrog Nephro-Check assay uas cuam tshuam txog kev puas tsuaj biomarkers ntawm lub voj voog ntawm tes raug ntes nrog qhov muaj feem yuav tsim AKI.
NEW HERBAL FORMULATION FOR CKD
Kev txheeb xyuas cov txheej txheem teb tshiab tuaj yeem pab ua ntej thiab siv cov cim kev raug mob raum txhawm rau txhim kho AKI kuaj mob. Ntau cov pov thawj qhia tias txoj hauv kev biomarker-based tuaj yeem cog lus rau kev txheeb xyuas cov neeg mob uas muaj kev pheej hmoo siab ntawm kev tsim AKI. Qhov no yog qhov tseem ceeb los tiv thaiv thiab kho qhov tshwm sim ntawm AKI thiab kws khomob cuam tshuam-AKI thiab pab rau kev tswj xyuas thaum ntxov ntawm cov neeg mob uas muaj tshuaj tua kab mob-AKI. Txawm hais tias muaj kev hloov pauv sai ntawm kev tshawb fawb hauv daim teb no, qhov kev kuaj mob ntawm lub raum biomarkers tau pom ntau qhov kev txwv thiab qhia txog qhov tsis sib xws hauv peb txoj kev paub, uas yuav cuam tshuam qhov tsis muaj cov qauv lees paub [140,216]. Qee qhov kev puas tsuaj biomarkers ua tau txawv raws li cov neeg mob tau kawm, muaj cov CKD uas twb muaj lawm, thiab seb puas muaj tus qauv kev pheej hmoo kho mob rau cov neeg muaj kev pheej hmoo siab tau siv ua ntej siv biomarkers. Yog li, cov pov thawj uas twb muaj lawm rau kev siv biomarkers los saib xyuas cov txiaj ntsig ntawm cov tshuaj thiab tiv thaiv lawv cov kev tswj hwm tseem tsis tau xav txog cov npe ntawm cov neeg tsis sib haum xeeb uas tuaj yeem cuam tshuam rau lawv qhov kev kuaj mob. Yog li, cov lus pom zoo los ntawm 23rd ADQI lub rooj sib tham pom zoo qhia tias kev sib txuas AKI cov ntsiab lus raws li sCr thiab cov zis tso zis nrog rau lub raum raug mob biomarkers yuav txhim kho qhov tseeb ntawm AKI chav kawm prognostication [146]. Hauv kev xaus, peb tsuas yog pib nkag siab txog qhov muaj txiaj ntsig zoo ntawm inte grating puas biomarkers rau hauv kev kho mob txhua hnub, thiab cov kev tshawb fawb yav tom ntej yuav tsum ua kom txaus siab rau qhov cuam tshuam ntawm kev saib xyuas neeg mob kom raug. Kev tshawb fawb ntxiv yog xav tau kom paub meej seb puas kuaj xyuas biomarkers puas tsuaj yam tsis muaj kev hloov pauv hauv cov zis tso zis lossis sCr cuam tshuam nrog lub raum tsis zoo thiab cov txiaj ntsig ntawm tus neeg mob.
Tus sau kev koom tes:Kev Sau-thawj cov kev npaj, LDC, GL, GV, FH-S., PR thiab EL; sau- tshuaj xyuas thiab kho, LDC, GL, EL, PR thiab VR Cov duab thiab cov rooj-drafting FR, LDC, EL, GL thiab VR Txhua tus kws sau ntawv tau nyeem thiab pom zoo rau cov ntawv luam tawm ntawm cov ntawv sau.
Nyiaj txiag:Qhov kev tshawb fawb no tau txais nyiaj los ntawm European Union's Marie Sklodowska-Curie kev sib raug zoo rau LDC, muab daim ntawv cog lus N◦ 845774. LDC kuj yog tus tau txais txiaj ntsig ntawm L'Oreal-Unesco rau Cov Poj Niam hauv Kev Tshawb Fawb. PR tau txais kev txhawb nqa los ntawm PRIN: progetti di ricerca di interesse Nazionale (2017T95E9X).
Kev tsis sib haum xeeb ntawm kev txaus siab:Cov kws sau ntawv tshaj tawm tsis muaj kev sib cav txog kev txaus siab.
Cov ntaub ntawv
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