Cov neeg mob raum tsis zoo yuav muaj tawv nqaij tsaus nti, mob rau mob rau, thiab ntxau me me. Nco ntsoov kom ceeb toom rau qhov kev ua txhaum no! Ntxov paub thiab kho ntxov
Oct 21, 2024
Calciphylaxis hauv Hemodialys cov neeg mob tsis tshua muaj kab mob thiab cov kab mob sib txawv thiab cov hlab ntsha, thiab cov tawv nqaij mob tawv nqaij thiab necrosis. Calciphylaxis yog ib txwm muaj nyob rau hauv cov neeg mob uas muaj tus kab mob raum xaus (ESRD). Nws yog tus cwj pwm me me ntawm kev suav me me thiab microthrombosis coj mus rau cov tawv nqaij uas nyuaj rau ntawm cov tawv nqaij thiab mob necrosis, nrog kev paub lub nroog siab thiab muaj kev nyuaj siab heev.
Nyem rau Cistance rau Mob Mob Mob Mob
1. Kev paub yooj yim ntawm calciphylaxis
Calciphylaxis, tseem muaj tus mob calcific uremific Nws yog tus cwj pwm los ntawm kev suav cov ntsiab lus ntawm cov xov xwm ntawm cov tub sab me me, uas tuaj yeem ua rau ischemia thiab subcutaneous necrosity. Cov yam ntxwv ua kom muaj zog yog viole, mob, plaque-zoo li subcutaneous nodules, thiab tuaj yeem nce mus rau ischemic / necrotic mob.
Causes and high-risk factors: The cause of calciphylaxis is not fully understood, but most people believe that it is related to bone and mineral metabolism disorders. Dialysis, the elderly, obesity (BMI>30), ntshav qab zib, hyperphosphatemia, cov tshuaj muaj txiaj ntsig, cov tshuaj tiv thaiv kab mob siab, kev siv tshuaj tiv thaiv kev tiv thaiv, kev tiv thaiv kev tiv thaiv kab mob thiab cov tshuaj tiv thaiv kev tiv thaiv thiab cov tshuaj tiv thaiv kab mob, Glucocorticoids, theem nrab Hyperparatathyroidism, thiab lwm yam Txhua yam muaj feem xyuam rau calcipylaxis.
2. Kev Tiv Thaiv Cov Kev Tiv Thaiv Cov calciphylaxis
Tswj siab ntau-pheej hmoo
Txhawm rau paub qhov muaj feem muaj kev pheej hmoo ntawm calciphylaxis, xws li hypercalcemia, hyperphosphazyroidism, thiab lwm yam kev ntsuas kev kho kom zoo. Piv txwv li, los ntawm kho cov lim ntshav, siv phosphate khi, ntxiv, kom muaj kev sib npaug ntawm cov calcium ntshav thiab ntshav phosphorus.
Kev tiv thaiv thiab kho cov hyperphosphatemia
Nws raug nquahu kom tswj hyperphosphatemia hauv CKD cov neeg mob kom txo qis kev pheej hmoo ntawm vascular calcular. Kev Tiv Thaiv thiab Kev Ntsuas Kho thiab Kev Xaiv Tsim Kev Noj Qab Haus Huv, Kev Ua Si Txiaj Ntsig Ua Si, Kev Tiv Thaiv Zoo Ua Si, thiab Tswj Tau Zoo ntawm. (Tsis sib xws) rau cov neeg mob CKD G3A-G5D uas xav tau pom zoo rau kev siv calcium-muaj phosphate binders. (2b)
Zam kev hypercalcemia
Nws raug nquahu kom zam zam hypercalcemia hauv CKD cov neeg mob kom txo qis kev pheej hmoo ntawm vascular calcular. Lim dej nrog cov calcium concentration ntawm 1. 25-1. 5 hli / u yog pom zoo. (2C) Nws raug nquahu kom raug kom raug cov calcium-muaj cov tshuaj thiab cov vitamin D thiab nws cov analogs. (Ungraded)
Kev Tiv Thaiv thiab Kev Kho Mob ntawm Cov Kev Herperaratathyroidism lossis hypoparathyroidism
Nws raug nquahu kom kho ob lub hypoparathyroidism thiab siv cov vitamin d thiab nws cov analogs, calcimimetics, los yog ua lwm yam kev sib koom tes. Thaum lub sijhawm kho, ntshav calcium thiab phosphorus qib yuav tsum raug saib xyuas kom tsis txhob saib xyuas hypercalcemia thiab hyperphosphatemia. (Ungraded)
Kho cov tshuaj siv
Txog cov tshuaj uas yuav ua tsis muaj calfinylaxis, xws li Warfarin thiab cov vitamin D, cov vitamin D, lawv yuav tsum zam kev siv tshuaj txo ntau li ntau tau. Yog tias lawv yuav tsum tau siv, tus neeg mob cov mob yuav tsum tau saib xyuas thiab txoj kev npaj kho mob yuav tsum tau hloov kho nyob rau lub sijhawm.
Kev Siv Zog Txhawb Nqa
Txhim kho tus neeg mob txoj kev noj haus thiab txhim kho kev tiv thaiv kev tiv thaiv tuaj yeem pab txo cov kev pheej hmoo ntawm calcipylaxis. Piv txwv, los ntawm cov calories txaus thiab protein txaus, tswj hwm tus neeg mob hnyav thiab cov leeg nqaij loj; Nyob rau tib lub sijhawm, ntxiv dag zog rau cov kev tu tawv nqaij, khaws cov tawv nqaij kom huv thiab ziab, thiab tsis txhob kis kab mob.
Lwm txoj kev xaiv
Lub micro-inflammatory lub xeev ntawm cov hlab lim dej yog cov neeg mob sib dhos, hais kom cov ntawv sau ua kom zoo lossis cov kev lim ntshav qab zib tuaj yeem txo cov vascular calcification. Sodium thiosulfate thiab vitamin K yuav ncua kev nce qib ntawm vascular calcification hauv CKD.
3. Kev kho mob ntawm calciphylaxis
Kev cim ntxov thiab kev kuaj mob
Kev paub thaum ntxov ntawm calciphylaxis yog qhov tseem ceeb. Thaum cov tsos mob thaum ntxov xws li Nadulularis, viethous plaques lossis harnthed nodules rau kev kuaj mob lub cev thiab cov ntsuas tseem ceeb kom paub meej tias kev kuaj mob.
Qhov txhab saib xyuas
Thaum cuam tshuam nrog cov qhov txhab los ntawm calcipylaxis, nws yog qhov tseem ceeb los xaiv cov khaub ncaws zoo. Qhov no tsis tsuas yog khaws ib puag ncig noo uas muaj kev ua kom puas tsuaj rau kho kom zoo, tab sis kuj ua tau zoo cais cov kev phom sij thiab tswj cov kev pheej hmoo kis mob. Nyob rau tib lub sijhawm, lub qhov txhab no ib txwm muaj thiab tshem tawm cov ntaub so ntswg nab kuab thiab cov zais cia tseem muaj cov kauj ruam tseem ceeb los txhawb kev kho mob kho kom zoo thiab tiv thaiv kev kis tus kab mob. Cov neeg kho mob yuav tsum tau them sai sai rau qhov kev ua kom lub qhov txhab kho kom zoo thiab kho tus neeg saib xyuas cov neeg laus nyob rau lub sijhawm.
Kev xoo
Cov teeb liab thiab infrared nyob rau hauv lub spectrum kho cuab yeej ua lub luag haujlwm tseem ceeb hauv kev kho cov calcipylaxis. Cov teeb pom no tuaj yeem nkag mus tob rau hauv daim tawv nqaij, txhawb kev sab laj hauv zos, ua kom nrawm dua qhov ploj mus, thiab yog li yooj yim kho kom zoo. Ib qho ntxiv, daim ntawv phototherapy tuaj yeem txo tus neeg mob qhov mob thiab txhim kho kev nplij siab ntawm kev kho mob. Thaum ua yeeb yam ntaub ntawv thaij duab, lub teeb siv zog thiab lub sijhawm raug kho kom raug muab kho raws li tus neeg mob qhov xwm txheej tshwj xeeb.
Hyperbaric oxygen kho
Hyperbaric oxygen txoj kev kho kom muaj qhov tseem ceeb rau kev kho cov tshuaj calcipylaxis los ntawm kev nce qib ib nrab ntawm cov ntaub thiab kev txhawb nqa txoj kev tsim kho tshiab thiab kev txhim kho. Qhov kev kho mob no tuaj yeem nrawm lub qhov txhab kho kom zoo, txo tus kab mob kom txo tau tus mob, thiab yuav txhim kho tus neeg mob lub siab tag nrho. Txawm li cas los xij, hyperbaric oxygen txoj kev kho yuav tsum tau nqa tawm hauv cov tuam tsev kws kho mob tshaj lij, thiab cov qauv kev qhia tau nruj thiab ua kom muaj kev kho mob zoo thiab muaj txiaj ntsig.
Kev tswj hwm qhov mob
Qhov mob los ntawm calciphylaxis ua rau mob hnyav rau cov neeg mob thiab yog ib qho nyuaj tshaj plaws ntawm cov txheej txheem kev kho mob. Yog li ntawd, kev tswj hwm qhov mob yog qhov tseem ceeb heev. Cov neeg kho mob kho mob yuav tsum tau saws cov kev tiv thaiv kev tiv thaiv tsis tu ncua thiab raws sijhawm raws li tus neeg mob tus mob mob thiab txhim kho lub neej zoo. Nyob rau tib lub sijhawm, nws tseem tsim nyog yuav tau them sai sai rau tus neeg mob lub hlwb lub paj thiab muab cov kev txhawb nqa hlwb thiab xis nyob.
Kev Kho Tshuaj
Hauv cov tshuaj kho ntawm calciphylaxis, tshuaj xws li sodium thiosulfate thiab bisphosphonates ua lub luag haujlwm tseem ceeb. Sodium thiosulfate tuaj yeem inhibit txoj kevcaicular txheej txheem thiab txo qhov kev loj hlob ntawm tus kab mob; Thaum Bisphosphorates pab tswj cov pob txha me metabolism thiab txo cov ntshav calcium thiab cov phosphorus qib. Thaum siv cov tshuaj no, koj yuav tsum ua raws li kws kho mob cov lus qhia thiab kev mob tshuaj kom ntseeg tau tias kev kho mob thiab tus neeg mob kev nyab xeeb. Tib lub sijhawm, cov neeg khomob kho mob tseem yuav tsum tau ua tib zoo saib xyuas kom hloov pauv ntawm tus neeg mob thiab kho cov phiaj xwm kho mob thiab phiaj xwm kev kho mob.
Cov Pab Cuam Tshwj Xeeb Kev Koom Tes Nrog
Cotifencia tiv thaiv yog qhov nyuaj thiab kev ua tiav hnyav uas yuav tsum muaj kev sib koom tes los ntawm pab pawg sib koom tes ntau pawg. Ntau lub chaw haujlwm xws li Neprological, dermatology, thiab yavatical phais yuav tsum ua haujlwm ze rau kev kho cov teebmeem thiab tus neeg mob lub neej muaj sia nyob.
Cistanche kho tus mob raum li cas?
ContancheYog cov tshuaj suav tshuaj ntsuab siv rau ntau pua xyoo los kho ntau yam kev noj qab haus huv, suav nrog mob raum. Nws yog muab tau los ntawm cov ntoo qhuav ntawmCistanche Squaticola, ib tug nroj tsuag ib txwm mus rau cov tiaj suab puam ntawm Tuam Tshoj thiab Mongolia. Cov nquag nquag tivthaiv cov cistance yogPhenylethanoid Glycosides, Echinacoside, thiabua yeeb yam, uas tau pom tias muaj cov txiaj ntsig zooLub raum noj qab haus huv.
Kab mob raum, tseem hu ua raws li cov kab mob raum, yog hais txog ib qho xwm txheej uas lub raum tsis ua haujlwm zoo. Qhov no tuaj yeem ua rau kev tsim cov khoom pov tseg thiab co co toxins hauv lub cev, ua rau muaj cov tsos mob thiab mob ntau yam. Contanche tuaj yeem pab kho mob raum kom dhau los ntawm ntau lub tshuab.
Firstly, cistanche tau pom muaj cov khoom diuretic, lub ntsiab lus nws tuaj yeem nce cov zis ntau thiab pab tshem cov khoom khib nyiab ntawm lub cev. Qhov no tuaj yeem pab daws rau lub nra ntawm ob lub raum thiab tiv thaiv cov buolup ntawm toxins. Los ntawm kev txhawb nqa DIuresis, contanche yuav pab txo cov ntshav siab, muaj kab mob mob raum siab.
Ntxiv mus, cistanche tau pom tias muaj kev cuam tshuam antioxidant. Kev ntxhov siab oxidative, tshwm sim los ntawm qhov tsis txaus ntseeg ntawm kev tsim cov dawb radicals thiab lub cev antioxidant defenses, ua lub luag haujlwm tseem ceeb hauv kev ua kom muaj mob raum. IES pab neutralize dawb radicals thiab txo qhov kev ntxhov siab oxidative, yog tiv thaiv lub raum los ntawm kev puas tsuaj. Cov phenysanoid glycosides pom hauv cistanche tau ua tau zoo rau hauv cov radicals dawb thiab inhibiting lipid peroxidation.
Tsis tas li ntawd, cistance tau pom tias muaj kev cuam tshuam los tiv thaiv. Kev voos yog lwm qhov tseem ceeb hauv kev txhim kho thiab kev nce qib ntawm lub raum kab mob. Cistance's Cistance cov khoom siv pab txo cov khoom siv pro-inflammatory uas yuav tsum tau ua, yog li kev ua pa tawm hauv lub raum.
Tsis tas li ntawd, cistanche tau pom tias muaj kev mob immunomodulatory. Hauv kab mob raum, lub cev tiv thaiv kab mob tuaj yeem yog dysregulated, ua rau mob ntau dhau thiab cov nqaij puas tsuaj. Contanche pab tswj lub cev tiv thaiv kab mob los ntawm kev tsim cov kev tsim khoom thiab kev ua haujlwm ntawm lub cev tiv thaiv kab mob, xws li t hlwb thiab macrophages. Qhov kev tiv thaiv kab mob no yuav pab txo qhov mob thiab tiv thaiv kev puas tsuaj ntxiv rau lub raum.
Ntxiv mus, contanche tau pom tias txhim kho lub zog rau lub raum ua haujlwm los ntawm kev txhawb nqa kev ua haujlwm ntawm lub raum uas muaj lub hlwb. Lub hlwb tubular epithelial cells ua si lub luag haujlwm tseem ceeb hauv kev pom thiab reausorption ntawm cov khib nyiab khoom thiab elecolytes. Hauv kab mob raum, cov hlwb no tuaj yeem puas, ua rau kev puas tsuaj ntawm lub raum tsis muaj dua. Contanche lub peev xwm los txhawb kev tsim kho tshiab ntawm cov cell no pab kho kom muaj nuj nqi redal kom zoo thiab txhim kho tag nrho lub raum noj qab haus huv.
Ntxiv rau cov teebmeem no ncaj qha ntawm ob lub raum, contanche tau pom tias muaj cov muaj txiaj ntsig zoo ntawm lwm cov nruab nrab thiab cov kab ke hauv lub cev. Qhov kev sib ze no rau kev noj qab haus huv yog tshwj xeeb hauv lub raum kab mob, raws li qhov xwm txheej feem ntau cuam tshuam ntau cov kabmob thiab cov tshuab. Che tau pom tias muaj cov teebmeem tiv thaiv kev tiv thaiv lub siab, lub plawv, thiab cov hlab ntshav, uas feem ntau cuam tshuam los ntawm mob raum. Los ntawm kev txhawb nqa kev noj qab haus huv ntawm cov kabmob no, contanche pab txhim kho kev ua haujlwm tag nrho cov haujlwm thiab tiv thaiv kev teeb meem ntxiv.
Hauv kev xaus, cistance yog cov tshuaj suav tshuaj ntsuab siv rau ntau pua xyoo los kho mob raum. Nws cov nquag tivtus muaj diuretic, antioxidant, anti-incoridatoratory, thiab cov kev pab cuam uas rov ua haujlwm dua thiab tiv thaiv lub raum los ntawm kev puas tsuaj ntxiv. , contistance muaj cov txiaj ntsig zoo rau lwm cov nruab nrog thiab cov tshuab, ua rau nws pab kab mob raum.
