Tshawb nrhiav Cov Cai Siv Tshuaj Ntawm Cov Tshuaj Suav Ntawm Xib Fwb Huang Wenzheng Rau Kev Kho Mob Raum Kab Mob Raws Li Cov Ntaub Ntawv Mining
Mar 13, 2022
Hu rau: Audrey Hu Whatsapp / hp: 0086 13880143964 Email:audrey.hu@wecistanche.com
Shao-Ning Dong, Yao-Guang Wang, Bing Xu, Liang Jin, Cui-Han Wang
1 Tianjin Academy ntawm Tsob Ntoo Suav Tshuaj Afflated Tsev Kho Mob, Tianjin, 300120, Tuam Tshoj;
2 Thawj Qhia Tsev Kho Mob ntawm Tianjin University of Traditional Chinese Medicine, Tianjin, 300193.China.3Tianiin University of Traditional suav tshuaj, Tianjin, 300193, Suav.
Qhov tseem ceeb:
Txoj kev tshawb no pom cov pob txha caj qaum thiab peb-theem network ntawm Suav tshuaj rau kev kho mob ntawm CKD los ntawm homogeneous network tsom xam. Cov 5 cov tshuaj uas siv ntau tshaj plaws yog Dan Shen (Radix Salviae Miltiorrhizae), Fu Ling (Poria), Huang Qin (Radix Scutellariae), Sheng Di Huang (Radix Rehmanmmiae Tsis ntev los no), thiab Sha Ren (Fructus Amomi Villosi), feem.
Cistanche txiaj ntsig: kho mob raum mob
Abstract:
Nyob rau xyoo tas los no,mob raum mob(CKD) tau txais kev saib xyuas ntau ntxiv vim nws qhov muaj feem ntau thiab muaj kev cuam tshuam tsis zoo. Cov kev xaiv kho mob tam sim no rau CKD raug txwv. Ntau tus neeg mob nrhiav lwm txoj kev kho mob, xws li tshuaj suav tshuaj (TCM). TCM tau siv dav hauv kev kho CKD tau ntau xyoo. Lub hom phiaj ntawm txoj kev tshawb no yog txhawm rau tshawb nrhiav cov cai tswj kev noj tshuaj ntawm xibfwb Huang Wenzheng txoj kev kho CKD nrog Suav tshuaj raws li cov ntaub ntawv mining. Cov ntaub ntawv txheej txheem tsim tau tsim rau 131 tus neeg mob CKD kho los ntawm Prof. Huang. Txoj kev sib tham hauv network tau siv los txheeb xyuas cov cai ntawm cov tshuaj suav tshuaj. Txoj kev tshawb no pom cov pob txha caj qaum thiab peb-theem network ntawm Suav tshuaj rau kev kho mob ntawm CKD los ntawm homogeneous network tsom xam. Cov 5 cov tshuaj uas siv ntau tshaj plaws yog Dan Shen (Radix Sahviae Miltiorrhizae), Fu Ling (Poria), Huang Qin (Radix Scutellariae), Sheng Di Huang (Radix Rehmanmniae Tsis ntev los no), thiab Sha Ren (Fructus Amomi Villosi), feem.
Ntsiab lus:Mob raum mob, Huang Wenzheng, Clinical xyaum, Complex network
Cistanche txiaj ntsig: kho mob raum
1. Keeb kwm
Mob raum mob(CKD) yog hom mob raum uas qhov glomerular filtration rate (GFR) tau qis dua RSV 60ml (min 1.73 m²) tsawg kawg 3 lub hlis. Lub raum puas yog kuaj los ntawm cov kab mob pathological txawv txav, lossis kev puas tsuaj rau lub raum kev ntsuas ntsuas (xws li ntshav, zis, lossis cov duab hauv plab)[1]. CKD hais txog ntau yam kab mob xws li mob glomerulonephritis, IgA nephropathy, thiab ntshav qab zib nephropathy. Kev tshawb fawb hauv teb chaws tsis ntev los no tau pom tias qhov kev nthuav dav ntawm CKD mus txog 10.8 feem pua hauv Suav teb [2]. CKD tau txais kev saib xyuas ntau ntxiv vim nws qhov muaj feem ntau, cov teebmeem tsis zoo, thiab cov nqi kho mob zoo heev3]. Cov kev kho mob tam sim no raumob raum mobtxwv. Ntau tus neeg mob nrhiav lwm txoj kev kho mob xws li tshuaj suav tshuaj (TCM).TCM tau dav siv los kho ntau yam kab mob hauv Suav teb rau ntau txhiab xyoo. TCM hauv kev kho mob ntawm CKD tuaj yeem txhim kho cov tsos mob, txo hematuria thiab proteinuria, txo cov tshuaj sab hnub poob 'kev phiv tshuaj, ua rau muaj kev tiv thaiv lub raum, thiab txhim kho lub neej zoo ntawm cov neeg mob, txhawm rau txhim kho cov tshuaj kho mob ntawm CKD. Kev tshawb fawb tau qhia TCM tuaj yeem txhim kho lub raum ua haujlwm los ntawm kev cuam tshuam cov glomerular pom tus nqi [4.5].
Huang Wenzheng(Lub Yim Hli 5, 1941-), txiv neej. Xib fwb Huang Wensheng yog tus kws kho mob thiab kws qhia ntawv hauv Department of Internal Medicine ntawm Thawj Tsev Kho Mob Koom Tes nrog Tianjin Traditional Chinese Medicine University. Nws kuj yog tus thib ob thiab plaub tus kws kho mob Suav qub qub nrog rau tus kws qhia paub txog keeb kwm yav dhau los. Prof. Huang muaj kev paub ntau los kuaj thiab kho CKD thiab ua tiav cov txiaj ntsig zoo hauv kev kho CKD. Tus kws sau ntawv sau cov ntaub ntawv kho mob ntawm xibfwb Huang Wenzheng cov tshuaj suav tshuaj suav tshuaj rau kev kho mob glomerulonephritis (CG), IgA nephropathy, mob ntshav qab zib nephropathy, thiab lub raum tsis ua haujlwm los tsim kom muaj cov ntaub ntawv kho mob. Txoj kev tshawb no tau nthuav qhia tus xibfwb Huang Wen Zheng txoj kev paub txog kev kho mobmob raum mobntawm herbal prescription law los ntawm retrospective tsom xam ntawm cov ntaub ntawv kho mob thiab cov ntaub ntawv mining txoj kev.
Cov txiaj ntsig Herba Cistanche
2. Cov ntaub ntawv thiab cov txheej txheem
2.1 Cov ntaub ntawv Source
Sau thiab sau cov ntaub ntawv kho mob rau CKD yog los ntawm xibfwb. Huang Wenzheng nyob rau hauv TCM Nephropathy Clinic of First Affiliated Hospital of Tianjin University of TCM los ntawm Lub Kaum Hli 20, 2003 txog Lub Ib Hlis 13, 2015. Cov ntaub ntawv no koom nrog 131 tus neeg mob thiab 1909 mus ntsib hauv tsev kho mob, suav nrog CG yam tsis muaj lub raum biopsy; IgA nephropathy thiab ntshav qab zib nephropathy nrog rau lub raum biopsy, nrog rau lub raum tsis ua haujlwm ntev tau nce los ntawm tus kab mob saum toj no nrog tsis-dialysis-yuav tsum tau lub raum tsis ua haujlwm.
2.2 Cov txheej txheem kuaj mob
2.2.1 Western tshuaj ntsuam xyuas cov qauv
①Ua raws li cov txheej txheem kuaj mob rau CKD hauv raum Kab Mob Qhov Ua Tau Zoo Tshaj Tawm (K / DOQl) tawm los ntawm National Raum Foundation (NKF) hauv xyoo 2002. CKD yog hais txog kab mob raum puas lossis GFR tsawg dua 60ml / (min·1.73m²) kav ntev li ntawm 3 lub hlis. Lub raum puas yog hais txog lub raum pathological abnormalities, los yog lub raum puas tsuaj indexes (xws li ntshav, zis, los yog imaging abnormalities)[1, 2].
(②) Raws li cov txheej txheem kuaj mob rau tus mob nephritis nyob rau hauv tus qauv tsim los ntawm Lub raum Kab Mob Pab Pawg ntawm Tuam Tshoj Journal of Internal Medicine editorial committee hauv Taiping, Anhui lub rooj sib tham nyob rau lub Rau Hli 1922 [6].
③Ua raws li cov txheej txheem kuaj mob rau IgA nephropathy nyob rau hauv Phau Ntawv Qhia Txog Kev Kho Mob thiab Kev Kho Mob: Cov Lus Qhia Txog Kev Kho Mob · Nephrology Volume [7] thiab Nephrology [8] tawm los ntawm Pab Pawg Kab Mob Raum ntawm Tuam Tsev Kho Mob hauv xyoo 2012.
④Ua raws li cov txheej txheem kuaj mob rau ntshav qab zib nephropathy hauv Phau Ntawv Qhia Txog Kev Kho Mob thiab Kev Kho Mob: Cov Txheej Txheem Kev Cai Kho Mob ·Nephrology Volume [7] tawm los ntawm Pab Pawg Kab Mob Raum ntawm Tuam Tsev Kho Mob hauv xyoo 2012 thiab cov kev kuaj mob kuaj mob rau ntshav qab zib nephropathy hauv WHO [9].
⑤Ua raws li cov txheej txheem kuaj mob rau lub raum tsis ua haujlwm nyob rau hauv tus qauv tsim los ntawm Pawg Kab Mob Raum ntawm Suav Phau Ntawv Xov Xwm ntawm Internal Medicine editorial committee hauv Taiping, Anhui lub rooj sib tham thaum Lub Rau Hli 1992 [8].
2.2.2 TCM Syndrome Diagnostic Criteria
Yog tias cov ntaub ntawv kho mob thawj zaug muaj xibfwb Huang Wenzheng cov ntawv sau tseg, cov ntaub ntawv kho mob thawj zaug yuav tsum yeej.
2.3 Kev soj ntsuam cov ntaub ntawv kho mob
2.3.1 Cov Txheej Txheem suav nrog
Tus kab mob ua tau raws li cov txheej txheem kuaj mob ntawm 4 kab mob tau teev tseg saum toj no. Cov ntaub ntawv kho mob tau ua tiav thiab txhim khu kev qha, Cov neeg mob tau kho nrog TCM decoction nkaus xwb, tsis noj lwm cov tshuaj suav. Tus neeg mob tsis tau txais kev lim ntshav.
2.3.2 Exclusion Criteria
Cov neeg mob uas muaj mob hnyav; Myocardial infarction lossis lub plawv tsis ua haujlwm; Hepatic insufficiency; Malignant hypertension thiab mob hnyav cerebrovascular; Mob ntshav qab zib ketoacidosis; Cov neeg mob uas mob malignancy thiab lwm yam mob tshwm sim los yog mob hnyav; Cov neeg mob uas tau txais kev hloov lub raum; Tsis muaj cov ntaub ntawv kho mob. 2.4. Txoj kev tshawb fawb
Tsim kom muaj cov ntaub ntawv kho mob hauv hluav taws xob nrog kev pab ntawm "Cov ntaub ntawv sib qhia ntawm Kev Kho Mob thiab Kev Tshawb Fawb Kev Kho Mob hauv TCM" (Cov txheej txheem sib qhia luv luv). Nkag mus rau hauv cov ntaub ntawv los ntawm kev siv PL / SQL Development software, siv SQL nqe lus rau query lub database, thiab txuag cov lus nug tshwm sim. Siv Liquorice software los ua homogeneous thiab heterogeneous network soj ntsuam los ntawm kev siv cov txheej txheem network nyuaj, thiab rho tawm 3 qib ntawm cov ntawv sau tshuaj los ntawm cov ntaub ntawv.
Cistanche herba thiab cistanche extract
3. Qhov tshwm sim
3.1 Kev tshuaj xyuas cov tshuaj
3.1.1 Tshuaj rau CG
Qib I sub-network ntawm cov tshuaj rau CG sawv cev rau thawj feem ntawm xibfwb Huang cov tshuaj hauv kev kho mob (Daim duab 1A), uas Huang Qi (Radix Astragali seu Hedysari) thiab Mai Dong (Radix Ophiopogonis) tuaj yeem noj yin thiab tau txais txiaj ntsig qi. , Shan Yao (Rhizoma Dioscoreae), Fu Ling (Poria), thiab Sha Ren (Fructus Amomi Villosi) tuaj yeem ua kom cov poov xab kom tshem tawm dampness, Bai Mao Gen (Rhizoma Imperatae) tuaj yeem txias ntshav kom tsis txhob los ntshav. Hauv qib 2 sub-network ntawm daim ntawv sau tshuaj, Bian Dou Yi (Pej Txiv Hmab Txiv Ntoo Dolichoris Album), Nws Ye (Folium Nelumbinis), Si Gua Luo (Retinervus Lufae Fructus), thiab Liu Yi San muaj cov tshuaj tshuaj ntsuab uas nquag siv rau lub caij ntuj sov- cua txias. Cov pab pawg ntawm Dan Dou Chi (Semen Sojae Preparatum), Sang Ye (Folium Mori), She Gan (Rhizoma Belamcandae), thiab Ku Xing Ren (Semen Armeniacae Amarum) zoo li muaj cov tshuaj ntsuab siv dav dav rau kev hnoos cua sov. (Daim duab 1B). Ntxiv mus, lub sub-network nyob rau theem thib peb qhia txog cov khub tshuaj ntsuab uas xibfwb Huang siv ntau zaus rau CG (Daim duab 1C). Ua ke nrog Wu Wei Zi (Fructus Schisandrae Chinensis), Wu Mei (Fructus Mume) tuaj yeem txhawb kev tsim cov kua dej hauv lub cev kom txo qis nqhis dej thiab noj yin los txhawb lub plawv. Kev sib xyaw ua ke ntawm DeLong (Lumbricus) thiab Hong Hua (Flos Carthami) tuaj yeem qhib cov ntshav thiab dredge collaterals. Dong Kui Zi (Fructus Mahal) nrog Wang Bu Liu Xing (Pej Vaccariae) tuaj yeem txo qis stranguria los ntawm diuresis. Tsis tas li ntawd, Bai Wei (Radix Cymanchi Atrati ).Yu Zhu (Rhizoma Polygonati Odorat) thiab Cong Bai (Bulbus Alli Fistulosi) tuaj yeem kho cua. -kub txias txuam nrog yin deficiency. Jiao Bin Lang (Semen Areca), Ji Nei Jin (Endothelium Corneum Gigerige Galli. Yu Jin (Radix Curcumae), Fo Shou (Fructus Citri Sarcadactylis), thiab Mai Ya (Fructus Hordei Germingtus) tuaj yeem kho gastrectasia thiab anorexia vim yog khoom noj khoom haus thiab Gua Lou (Fructus Trichosanthis), Xie Bai (Bulbus Alli Macrostemomis), Jiang Xiang (Lignum Dalbergiae Odoriferae), Yan Hu Suo (Rhizoma Corydalis), San Qi (Radix Notoginseng). Hu Bo (Succinum) thiab Gui Ban ( Carapax Testudinis) tuaj yeem kho mob hauv siab, angina thiab palpatataion.
3.1.2 Kev tshuaj ntsuam xyuas ntawm IgA nephropathy
Cov kev tshawb fawb tseem ceeb tau pom tias Xib Fwb Huang tau siv txoj kev txhawb nqa yin kom tau txais txiaj ntsig qi [Sheng Huang Qi (Radix Astragali seu Hdsari), Tai Zi Shen (Radix Pseudostellariae). Mai Dong (Radix Ophiopogonis)] ua ke nrog cov txheej txheem invigorating spleen rau tshem tawm dampness [Sha Ren (Fructus Amomi Villosi), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Fu Ling (Poria), Shi Wei (Folium Pyrrosiae), Bi Rhizoma Dioscoreae Hypoglaucae)], thiab txoj kev ntawm dredging san jiao [Chai Hu (Radix Bupleuri), Huang Qin (Radix Scutellariae)] kho IgA nephropathy (Daim duab 3).
3.1.3 Lub Ntsiab Tshuaj Ntsuam Xyuas rau Ntshav Qab Zib Nephropathy
Peb pom cov ntawv sau tseem ceeb rau Diabetic Nephropathy (DN) raws li kev txheeb xyuas pob txha caj qaum (Daim duab 4), uas Sheng Huang Qi (Radix Astragali seu Hedysari), Tai Zi Shen (Radix Pseudostellariae), Mai Dong (Radix Ophiopogonis) tau siv rau. tonifying qi thiab nourishing yin thiab Shan Zhu Yu (Fructus Comi), Rou Gui (Cortex Cinmnamomi), Tu Si Zi (Semen Cuscutae) aimed to invigorate tus po thiab raum. Fu Ling (Poria), Fang Ji (Radix Stephaniae Tetrandrae), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Tu Fu Ling (Rhizoma Smilacis Glabrae) ua lub luag haujlwm ntawm dampness remover thiab Gui Jian Yu (Ramulus Euomymi), Tao Ren (Pej Persicae). ), Jiu Da Huang (Radix et Rhizoma Rhei) ua raws li cov neeg ua haujlwm pabcuam ntshav. Cov tshuaj los ntawm xib fwb Huang tau concocted rau tonifying qi, nourishing yin thiab invigorating spleen thiab lub raum kom ntxiv dag zog rau lub hauv paus thiab invigorating ntshav, thiab tshem tawm dampness mus tshem tawm cov tsos mob.
3.1.4 Lub Ntsiab Tshuaj Ntsuam Xyuas rau Kev Kho Mob Raum Tsis Zoo
Nyob rau hauv tshuaj kho mob CRF, Sheng Huang Oi (Radix Astragali seu Hedysari), Mai Dong (Radix Ophiopogonis), Tai Zi Shen (Radix Pseudostellariae), Zhi Gan Cao (Radix Ghcyrrhizae) yog tsuas yog rau tonifying qi thiab nourishing (yin, Dan Shen). Radix Salviae Miltiorrhizae), Dang Gui (Radix Angelicae Sinensis), Yi Mu Cao (Herba Leonuri), Gui Jian Yu (Ramulus Euomymi), Jiu Da Huang (Radix et Rhizoma Rhei) yog tsom los txhawb cov ntshav ncig thiab ua kom cov ntshav muaj zog. Fu Ling (Poria) thiab Sha Ren (Radix Adenophorae) tau siv los rov qhia tus po, He Shou Wu (Radix Polygomi Multiflori) thiab Tu Si Zi (Semen Cuscutae) muaj lub luag haujlwm ntawm lub raum tonifying. Tu Fu Ling (Poria) thiab Bi Xie (Rhizoma Dioscoreae Hypoglauca) npaj kom tshem tawm dampness (Daim duab 5). Kev tswj hwm qi Xue yin yang yog lub hauv paus ntsiab lus tseem ceeb rau kev kho CRF coj los ntawm xibfwb Huang, thiab peb yuav tsum ua tib zoo saib xyuas kom muaj zog spleen thiab ntxiv qi, thiab txhawb lub raum, thiab ua kom cov ntshav ncig.
3.2 Kev tshawb fawb hauv kev siv tshuaj
3.2.1 Kev txheeb xyuas zaus ntawm cov tshuaj ntsuab Tom qab xam qhov zaus ntawm qhov tshwm sim ntawm 100 tsw tshuaj ntsuab, tshuaj ntsuab tau pom ntau dua 50 zaug (Table 1). Sab saum toj 25 yog Dan Shen (Radix Salviae Miltiorrhizae), Fu Ling (Poria), Huang Qin (Radix Scutellariae), Sheng Huang Qi (Radix Astragali seu Hedysari), Sha Ren (Fructus Amomi Villosi), Mai Dong (Radix Ophiopogonis), Gan Cao (Radix Gbcyrrhizae), Shan Yu Rou (Fructus Cormi), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Chai Hu (Radix Bupleuri1), Tai Zi Shen (Radix Pseudostellariae).Bai Mao Gen (Rhizoma Imperatae), Dang Gui (Radix Pseudostellariae). Angelicae Sinensis), Shan Yao (Rhizoma Dioscoreae), Sheng Di Huang (Radix Rehmanmiae Tsis ntev los no), Shi Wei (Folium Pyrrosige), Lu Han Cao (Pyrola Calliantha), Di Jin Cao (Herba Euphorbiae Humifusae), Gui Jian Yu (Rammulus Euomymi). ), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Ze Xie (Rhizoma Alismatis). Tu Fu Ling (Rhiomg Smilacis Glabrge). Xiao Ji (Herba Corsi). Yi Mu Cao (Herba Leomuri), Mu Dan Pi (Cortex Moutan Radicis).
3.2.2 Kev txheeb xyuas cov pob txha caj qaum rau cov tshuaj uas nquag siv
Tag nrho cov tshuaj feem ntau siv rau kev soj ntsuam cov pob txha caj qaum muaj 19 tshuaj ntsuab (Daim duab 6). Lawv tau muab faib ua plaub pawg raws li lawv txoj kev sib koom ua ke. Thawj pab pawg yog Di Jin Cao (Herba Euphorbiae Humifusae) thiab Ji Cai Hua (Capsella Bursapastoris Medic), uas yog lub hauv paus ntawm kev kho cov ntshav tso zis; pawg thib ob yog Jie Geng (Radix Platycodonis) thiab Gan Cao (Radix Glycyrrhizae) yam tsis muaj kev qhia tshwj xeeb hauv kev kho mob; pawg thib peb yog Fu Ling (Poria), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Ze Xie (Rhizoma Alismatis), Mu Dan Pi (Cortex Moutan Radicis), Zhi Gan Cao (Radix Ghcyrhizae) thiab Sha Ren (Fructus Amomi illos), uas yog siv rau invigorating spleen rau diuresis; pawg plaub muaj ntau yam tshuaj ntsuab xws li Tai Zi Shen (Radix Pseudostellariae) thiab Mai Dong (Radix Ophiopogonis) uas yog siv rau supplementing Qi thiab nourishing Yin; Chai Hu (Radix Bupleuri) thiab Huang Qin (Radix Scutellariae) uas yog siv los kho Shaoyang; Bai Hua She She Cao (Herba Hedyotis) thiab Bi Xie (Rhizoma Dioscoreae Hypoglauca) uas yog siv rau kev tshem tawm cua sov thiab txhawb nqa diuresis; Dan Shen (Radix Salviae Miltiorrhiae) thiab Gui Jian Yu (Ramulus Euonymi) uas yog siv los txhawb cov ntshav ncig kom tshem tawm cov ntshav stasis thiab Bai Mao Gen (Rhizoma Imperatae) siv los ua kom cov ntshav txias thiab hemostasis.
3.2.3.Level 3 network tsom rau cov tshuaj uas nquag siv
Qib 1 sub-network sawv cev rau 10 tshuaj ntsuab rau kev kho mobmob raum mob, xws li raw Huang Qi (Radix astragali) Chai Hu (Radix Bupleuri), Huang Qin (Radix Scutellariae), Bai Mao Gen (Rhizoma Imperatae), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Dan Shen (Radix Sahviae Miltiorrhizae), Fu Ling (Poria), Shan Zhu Yu (Fructus Cormi), Sha Ren (Fructus Amomi Villosi) thiab Mai Dong (Radix Ophiopogonis) Shui Zhi (Hirudo) (Daim duab 7)
Theem 2 sub-network sawv cev rau 42 tshuaj ntsuab siv los kho hom mob lossis tus mob tseem ceeb thiab nrog cov tsos mob, uas tau muab faib ua plaub pawg (Daim duab 8). Thawj pab pawg yog Mo Han Lian (Herba Eclipse) siv rau kev tsis txaus ntawm daim siab thiab lub raum; pab pawg thib ob yog cov tshuaj cab xws li Chuan Shan Jia (Squama Manis), Tu Bie Chong (Eupolphaga Seu Steleophaga), uas yog siv rau kev kho mob collateral stasis thiab obstructive; pawg thib peb yog tshuaj ntsuab txhua yam siv los ua kom cov ntshav txias thiab hemostasis. xws li Chao Pu Huang (Pollen Tiphae), Ou Jie (Nodus Nehumbimnis Rhizomatis), thiab Ce Bai Ye (Cacumen Platyclad), uas yog cov tshuaj sib xyaw ua ke rau kev kho cov ntshav hauv cov zis los ntshav pawg plaub, muaj 10 tshuaj ntsuab ntawm sab laug, xws li Ban Lan Gen (Radix Isatidis), Zhu Ye (Herba Lophatheri), Niu Bang Zi (Fructus Arctic), Sang Ye (Folaum Mori), Bo He (Herba Menthae), Dan Dou Chi (Semen Soige Preparatum). Zhe Bei Mu (Bulbus
Thunbergi), Jing Jie (Herba
Fritillarae T.
Schizonepetae) Fang Feng (Radix Saposhmikovice) thiab Zhi Ke (Fructus Auranti), uas yog siv rau kev tshem tawm cua los daws cov sab nrauv thiab tshem tawm cov khoom siv hluav taws xob thiab tshuaj lom, thiab tshwj xeeb hauv kev kho mob hauv Wei theem syndrome, Oi theem syndrome, thiab cov kab mob nyob rau sab sauv. -jiao. Muaj 9 tshuaj ntsuab nyob nruab nrab, xws li Yuan Shen (Radix Scrophulariae), Di Gu Pi (Cortex Lycii). Ge Gen(Radix Puerariae), Hai Piao Shao(Os Sepiellae seu Sepiae), Bai Bian Dou (Semen Dolichoris Album), Zi Su Geng(Perilla Sem), Qing Ban Xia (Rhizoma Pinelliae Preparata), Chen Pi (Pericarpium Citri Reticulate) , thiab Chao Yi Yi Ren (Semen Coicis), uas yog siv los txhawb Yin los kho lub plab, thiab tshwj xeeb tshaj yog kho cov mob hauv nruab nrab-jiao.Muaj 16 tshuaj ntsuab ntawm sab xis, thiab qee cov tshuaj ntsuab inclined kho cov kab mob hauv qab. -jiao, xws li Sang Ji Sheng (Herba Taxilli), Niu Xi (Radix Achyranthis Bidentatae), Fu Pen Zi (Fructus Rubi), Jin Ying Zi (Fructus Rosae Laevigatae), Qian Shi (Pej Xeem Euryales), Yi Zhi Ren (Alpinia). oxyphylla Mig), Shi Chang Pu (Rhizoma Acori Tatarinowi), thiab Xi Xian Cao (Herba Siegesbeckiae), thiab qee qhov yog siv rau kev kho cov ntshav theem syndromes, xws li Chuan Xiong (Rhizoma Ligustici Chuanxiong), Chi Shao (Radix Paeoniae Rubra), Ji Xue Teng (Caulis Spatholobi), Bai Shao (Radix Paeoniae Alba) thiab Shu Di (Radix Rehmanmniae Preparata). Theem 3 sub-network sawv cev rau kev kho tshuaj raws li cov tsos mob, suav nrog cov tshuaj nquag siv: Chao Gu Ya (Fructus Setariae Germinatus)-Chao Dao Ya (Fructus Oryzae Germinatus), Tian Ma (Rhizoma Gastrodiae)-Gou Teng (Ramuhus Uncariae Cum Uncis), She Gan (Rhizoma Belamcandae)-Mu Hu Die (Semen Oroxyi), Chong Wei Zi(Fructus Leonuri)-Sheng Pu Huang (Pollen Typhae), Liu Ji Nu(Herba Artemisia Anomalae)- Ma Bian Cao(Herba Verbena), Yin Chen (Herba Artemisia Scopariae)- Ji Gu Cao (Herba Abri), Shi Hu (Herba Dendrobi)-Jin Yin Hua (Flos Lonicerae) (Daim duab 9).
Cov txiaj ntsig Cistanche: tshem tawm dawb radicals
Kev sib tham
Hauv cov ntsiab lus ntawm kev kho CDK kev kho mob los ntawm cov tshuaj suav tshuaj, xibfwb Huang Wenzheng tau tawm tswv yim los kho cov kab mob no raws li TCM syndrome sib txawv thiab kev kho mob thiab coj cov kab mob sab hnub poob ntawm cov kab mob mus rau tib lub sijhawm, uas tseem hu ua Kev sib xyaw ua ke ntawm cov kab mob thiab cov tsos mob sib txawv. Peb tuaj yeem xaus qhov tseem ceeb cov tshuaj thiab triple-tshuaj cai lij choj ntawm xibfwb Huang Wenzheng hauv kev kho CG, IgA nephropathy, ntshav qab zib nephropathy, thiab lub raum tsis ua haujlwm los ntawm txoj hauv kev sib tham hauv network. Cov yam ntxwv ntawm kev kho mob thiab tshuaj ntsuab yog raws li nram no: 1) tonifying qi thiab yin: Huang Qi (Radix Astragali seu Hedysari), Bai Zhu (Rhizoma Aractylodis Macrocephalae), Fang Feng (Radix Saposhmnikoviae); 2) ntxiv dag zog rau tus po thiab txhawb lub raum: Sheng Huang Qi (Radix Astragali seu Hedysari), Shan Zhu Yu (Fructus Cormi), Chai Hu (Radix Bupleuri), Dan Shen (Radix Salviae Miltiorrhizae), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Tu Fu Ling (Rhizoma Smilacis Glabrae), Gui Jian Yu (Ramulus Euonymi), Tu Si Zi (Semen Cuscutae), Tai Zi Shen (Radix Pseudostellariae), Sha Ren (Fructus Amomi Villosi), Huang Qin (Radix Scutellariae), Gan Cao (Radix Glhyeyrhizae), Shan Yao (Rhizoma Dioscoreae), Fu Ling (Poria), Dang Gui (Radix Angelicae Sinensis), Yi Mu Cao (Herba Leomuri ); 3) dispersing ntshav stasis thiab dredging collaterals: Huang Qi (Radix Astragali seu Hedy. ), Tai Zi Shen (Radix Pseudostellariae), Dan Shen (Radix Salyiae Miltiorrhizae), Yi Mu Cao (Herba Leonuri), Gui Jian Yu (Ramulus Euomymi), Tao Ren (Semen Juglandis), Dang Gui (Radix Angelicae Sinensis), Tu Si Zi (Semen Cuscutae), Sha Ren (Fructus Amomi Vllosi), Shan Zhu Yu (Fructus Corni), Fu Ling (Poria), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Hua ng Qin(Radix Scutellariae), Tu Fu Ling(Rhizoma Smilacis Glabrae), Tu Bie Chong (Eupolyphaga Seu Steleophaga); 4) Shu-li triple energizer: Sheng Huang Qi (Radix Astragali seu Hedysari), Chai Hu (Radix Bupleuri), Huang Qin (Radix Scutellariae), Dan Shen (Radix Salviae Miltiorrhizae), Tai Zi Shen (Radix Pseudostellariae), Mai Dong (Radix Ophiopogonis), Bi Xie (Rhizoma Dioscoreae Hypoglaucae), Shi Wei (Folium Prrosiae), Bai Mao Gen (Rhizoma Imperatae), Xiao Ji (Herba Cirsii). Bai Hua She She Cao (Herba Hedvotis), Zhu Ma Gen (Radix Boehmeriae), Di Jin Cao (Herba Euphorbiae Humifusae), Lu Han Cao (Pyrola Calliantha), Shan Zhu Yu (Fructus Cormi).
Cistanche txiaj ntsig: kho mob raum
Kev siv
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