Cov xwm txheej tam sim no ntawm Pharmacological teebmeem ntawm Glycosides Ntawm Cistanches Herba
Apr 23, 2024
2.5 Txhim kho kev tiv thaiv
Jiang Xiaoyan et al [saib cov teebmeem ntawm GCs ntawm kev hloov pauv ntawm cov thymus, spleen, thiab testicles ntawm nas tom qab irradiation nrog Coy rays. Cov txiaj ntsig tau pom tias CCs tuaj yeem txhawb kev puas tsuaj ntawm thymus, spleen, testicular biofilm, thiab organelles hauv cov nas tom qab hluav taws xob. Nws tau pom zoo tias GCs tiv thaiv ultrastructure ntawm lub cev rhiab hauv cov nas irradiated los ntawm kev tiv thaiv oxidation thiab txhawb DNA thiab RNA synthesis. Zou Liya Yiming! 7 et al. pom tias CCs tuaj yeem txhim kho qeeb-hom hypersensitivity cov tshuaj tiv thaiv hauv cov nas irradiated, txhim kho T lymphocyte proliferation teb thiab interleukin -2 kev ua, nce thymus Performance index, yog li tswj ib txwm.T lymphocyte ua haujlwm.
2.6 Tiv thaiv daim siab
Lub siab fibrosisyog tus txheej txheem ntawm kev puas tsuaj thiab kho tom qab daim siab mob rov qab los yogmob mob. Feem ntaukab mob siabNws thiaj li loj hlob mus rau theem lig cirrhosis los ntawm daim siab fibrosis. Cov kev tshawb fawb tau pom tias GCs cuam tshuam cov platelet-derived kev loj hlob zoo-BB-kho kev qhia ntawm nas hepatic stellate hlwb los ntawm kev tswj cov kev qhia ntawm platelet-derived growth factor (PDGF)/extracellular signal-regulated kinase 1/2 (ERK1/2) taw qhia txoj kev. Proliferation activation 8], yog li inhibiting cov txheej txheem ntawm daim siab fibrosis,
Nws yuav siv sij hawm ntev npaum li cas rau CISTANCHE ua haujlwm?
2.7 Kev kho cov kab mob spermatogenic
Zhao Donghai et al. 9] txhaj nas nrogcyclophosphamidelos tsim cov spermatogenic teeb meem nas qauv, thiab tom qab ntawd muab Cistanche tubulosa phenylethanoid glycoside los ntawm gavage. Cov txiaj ntsig tau pom tias Cistanche tubulosa phenylethanoid glycoside tuaj yeem txhawb nqa phev ceev thiab phev motility hauv cov nas hauv txhua pab pawg. tus nqi, nce qib Testosterone nyob rau hauv cov qog nqaij hlav homogenate, cov qauv testicular yog qhov tseeb, thiab cov spermatogenic hlwb raug teeb tsa zoo, nruj thiab tsis tu ncua. Liang Hualun [20] et al. tsim ib qho hauv vitro phev oxidative kev puas tsuaj qauv, siv Raman spectroscopy thev naus laus zis los kuaj xyuas cov kev hloov pauv hauv cov phev nuclear DNA, thiab tshawb xyuas cov txiaj ntsig ntawm Cistanche tubulosa phenylethanol glycoside ntawm cov phev oxidative puas. Kev tshawb fawb tau pom tias Raman spectrum siv thiab spectral peak hloov ntawm oxidatively puas phev cell nuclei hloov pauv loj. Tom qabCistanche tubulosa phenylethanoid glycosideyog muab, Raman spectrum siv thiab spectral peak hloov pauv hloov pauv tau zoo heev, ua pov thawj tias Cistanche tubulosa phenylethanoid glycoside tuaj yeem ua rau qee yam, nws inhibits oxidative puas tsuaj los ntawm cov oxidants muaj zog rau tib neeg phev DNA.
2.8 Lwm yam
Raws li lub ntsiab active ingredient ntawmCistanche extract, CCs kuj muaj tshuaj tua kab mob, tiv thaiv kab mob, tiv thaiv qaug zog, thiab txhim kho kev sib deev ua haujlwm [2]
3 Kev sib tham
Raws li kuv lub teb chaws cov neeg muaj hnub nyoog thiab cov neeg xav tau kev noj qab haus huv nce ntxiv, Cistanche tubulosa, ua ib qho tseem ceeb ntawm cov tshuaj suav tshuaj ntsuab, muaj txiaj ntsig zoo thiab muaj kev cia siab dav thiab tseem ceeb hauv kev txhim kho thiab siv cov tshuaj thiab cov zaub mov noj qab haus huv. Nyob rau hauv xyoo tas los no, kev vam meej tau ua tiav nyob rau hauv kev tshawb fawb ntawm cov tshuaj pharmacological thiab tshuaj Cheebtsam ntawm Cistanche tubulosa. Raws li nws cov khoom xyaw tseem ceeb, cov tshuaj pharmacological thiab cov txheej txheem ntawm cistanche tubulosa glycosides kuj tau txais kev saib xyuas ntau dua. Raws li qhov no, kev tshawb fawb tob tob yuav tsum tau ua los ntawm nws cov txheej txheem tshwj xeeb ntawm kev ua.
Cov ntaub ntawv:
[1] Meng Shengxi, Huo Qingping, Kev tshawb fawb nce qib ntawm cov khoom xyaw nquag ntawm Cistanche tubulosa ntawm lub paj hlwb [J]. Suav Journal of Traditional Chinese Medicine Information, 2016, 23(10): 123-126. National Pharmacopoeia Commission, Pharmacopoeia of the People's Republic of China (Part 1). [M]. Beijing: Chemical Industry Xovxwm, 2010: 126.
[3] Chen Xu, Qin Wei, Yang Shasha, et al. Kev tshawb nrhiav kev nce qib ntawm kev siv tshuaj kho mob thiab kev ua tau zoo ntawm Cistanche tubulosa [J]. Strait Pharmacy, 2017, 29(5): 1-4. [4] Hu Jiaqi, Feng Jiayuan, Cistanche tubulosa Tshuaj muaj pes tsawg leeg thiab cov tshuaj pharmacological [J]. Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Tshuaj Suav, 2012, 4(15)26-28.
Wang Xiaowen, Jiang Wanyan, Wulia Yiming, et al. Hauv vitro scavenging ntawm dawb [5] radicals los ntawm tag nrho glycosides ntawm Cistanche tubulosa thiab nws cov nyhuv tiv thaiv DNA puas los ntawm OH·[J]. Suav Pharmaceutical Journal, 2000, 36(1):29 -33.
Wu Liya Yiming, Wang Xiaowen, Wubuli Aishan, thiab al., tiv thaiv cov nyhuv ntawm tag nrho glycosides ntawm Cistanche tubulosa ntawm nas hlwb[6] hypoxia[J]. Pharmacological Communications, 2003, 20(1):73.[7]XIA0 Q, YAN P, MA Cov teebmeem ntawm tag nrho glycosides (CCs) ntawm synaptic morphological plasticity nyob rau hauv cov nas aging sai[8][J]. Phau ntawv Journal of Baotou Medical College, 2017, 33(8):
