Kev nkag siab zoo ntawm Parkinson's, Paub tias Parkinson's Disease Tsis ntshai
Apr 13, 2022
Parkinson's disease yog ib hom kab mob degenerative ntawm lub paj hlwb hauv cov neeg laus thiab cov laus. Nws yog feem ntau tshwm sim raws li kev txav qeeb, tshee tshee hauv cov ceg, poob ntawm kev hloov pauv ntawm lub cev, ua kom nruj, sau ntawv me me thiab me me, kev tawm suab ntau dua thiab tsis meej, thiab lwm yam. Cov tsos mob, tab sis lub zog ntawm cov leeg ntawm cov ceg ceg tsis muaj zog. tsis muaj zog heev. Cov lus piav qhia ntxov tshaj plaws ntawm tus kab mob yog los ntawm tus kws kho mob Askiv Askiv James Parkinson, uas tau hu ua tus kab mob "Parkinson's disease" hauv kev hwm ntawm tus kws kho mob, uas tseem hu ua "tremor paralysis" hauv Suav teb. Yog tias koj muaj cov tsos mob xws li lub cev tshee tshee, kev txav qeeb, cov leeg nqaij tawv, thiab kev hais lus tsis meej, koj yuav tsum nrhiav kev kho mob raws sij hawm.
Cov tsos mob ntawm lub cev muaj zog, suav nrog kev so tremor, cov leeg nqaij rigidity, bradykinesia, thiab lwm yam. Kev tshee tshee feem ntau yog qhov tshwm sim ntxov tshaj plaws thiab yog vim li cas rau kev nrhiav kev kho mob. Tus yam ntxwv ntawm so tremor yog tias qhov tshee tshwm sim nyob rau hauv lub xeev tseem, tes taw zoo li dov ib ntsiav tshuaj, qhov tshee tshee hnyav zuj zus thaum tus neeg mob muaj kev xav lossis ntxhov siab, thiab nws tuaj yeem ploj mus thaum pw tsaug zog. Qee cov neeg mob kuj muaj kev nruj ntawm cov ceg los yog lub cev, nyuaj rau kev txav zoo, thiab kev txav qeeb. Tsis tas li vim tias tus neeg mob tsis nrog kev so ntawm kev tshee, cov tsos mob no feem ntau tsis quav ntsej los ntawm tus neeg mob lossis kho raws li kev mob caj dab, ncauj tsev menyuam thiab lumbar spondylosis, thiab lwm yam, txawm tias lawv mus rau lub chaw kho mob neurology, lawv yuav raug kho raws li kab mob cerebrovascular.
Yog li ntawd, txhua leej txhua tus yuav tsum paub hais tias nyob rau hauv lub cev muaj zog cov tsos mob ntawm Parkinson tus kab mob, qeeb zog yog qhov tseem ceeb tshaj plaws kev ua tau zoo. Cov neeg mob tuaj yeem hnov tias kev txav zoo xws li txhuam hniav, ntaus qe, dov dumpling wrappers, tying nyees khawm, thiab tying shoelaces tsis yooj yim, thiab kev sau ntawv yuav me dua. Thaum taug kev, txhais caj npab tsis viav vias ywj pheej, lub cev txav mus rau pem hauv ntej, lub pace yuav me dua, cov lus qhia yuav tiaj tus, thiab lwm yam. Qee cov neeg mob tsuas muaj zog ntawm cov ceg thiab tsis muaj tshee, uas yog hu ua Parkinson's non-tremor. Cov neeg mob uas tsis tshee yog feem ntau yuav raug saib xyuas. Yog li ntawd, kev kuaj mob ntawm Parkinson's disease, tshwj xeeb tshaj yog kev kuaj mob ntxov, tseem yuav tsum tau txiav txim siab ntawm tus kws kho mob hlwb, tshwj xeeb tshaj yog tus kws kho mob tshwj xeeb hauv Parkinson's disease.
Cov tsos mob tsis yog lub cev muaj zog ntawm tus kab mob Parkinson, feem ntau suav nrog:
1. Psychoneurological tsos mob: kev nyuaj siab, ntxhov siab vim, apathy, dementia, delirium, thiab lwm yam.
2. Kev pw tsaug zog tsis zoo: insomnia, pw tsaug zog ntau thaum nruab hnub, ntau yam npau suav, npau suav tiag tiag, nyob tsis tswm ceg, REM pw tsaug zog tsis zoo, thiab lwm yam.
3. Autonomic dysfunction: nquag tso zis, ceev, nce nocturia, hyperhidrosis, orthostatic hypotension, ntog, kev sib deev tsis ua hauj lwm, thiab lwm yam.
4. Cov tsos mob ntawm plab hnyuv: salivation, poob ntawm saj, dysphagia, choking, xeev siab, cem quav, thiab lwm yam.
5. Kev puas siab puas ntsws: tsis hnov tsw tsw, loog loog ntawm ceg, mob, thiab lwm yam.
6. Lwm cov tsos mob: qaug zog, qhov muag tsis pom kev, nce tso tawm ntawm cov qog sebaceous, hnyav nce lossis poob, pob txha pob txha, thiab lwm yam.
Qee yam ntawm cov tsos mob tsis yog lub cev muaj zog tshwm sim tom qab cov tsos mob ntawm tus kab mob Parkinson, xws li kev puas hlwb, feem ntau tshwm sim ua ntej cov tsos mob ntawm tus kab mob Parkinson tshwm sim, thiab nyob rau hauv tag nrho cov txheej txheem kab mob, Piv txwv li, nquag tso zis, cem quav, kev nyuaj siab. , tsis hnov tsw tsw, pw tsaug zog tsis zoo, tshwj xeeb tshaj yog ib hom kev pw tsaug zog tsis meej tshwm sim raws li qw, xuas nrig ntaus thiab ncaws hauv pw tsaug zog, feem ntau yog nrog npau suav phem, zoo li lawv tau ua tawm. Peb hu nws ceev ceev qhov muag txav tus cwj pwm tsis zoo, los yog RBD luv luv, uas feem ntau tshwm sim ob peb xyoos los yog ntau tshaj kaum xyoo ua ntej tshaj tus kab mob Parkinson.
Yuav kho tus kab mob Parkinson li cas?
Tam sim no, cov tshuaj sab hnub poob txoj kev kho mob ntawm Parkinson tus kab mob feem ntau yog los ntawm kev hloov kho dopamine supplementation. Txawm li cas los xij, thaum ntxov daim ntawv thov ntawm cov koob tshuaj loj ntawm levodopa npaj tuaj yeem ua rau kom muaj teeb meem ntawm lub cev muaj zog. Yog li ntawd, nyob rau theem pib ntawm tus kab mob Parkinson, cov tsos mob ntawm kev kho mob tsis cuam tshuam rau lub neej txhua hnub. Nws raug nquahu kom siv cov tshuaj suav tshuaj suav tshuaj, kho lub cev thiab kho lub cev, thiab lwm yam, txhawb cov neeg mob kom tawm dag zog ntau dua, sunbathe, haus dej tshuaj yej ntsuab, tswj kev ua neej zoo, thiab sim ncua kev siv cov tshuaj Western thiab noj tshuaj. Cov koob tshuaj maj mam nce mus txog thaum nws tuaj yeem ua tau raws li kev ua haujlwm niaj hnub. Kev kho mob phais (lub hlwb sib sib zog nqus DBS) yog ib qho zoo ntxiv rau kev kho mob sab hnub poob. Kev kho kom rov zoo, kho kev puas siab puas ntsws, thiab kev saib xyuas neeg mob zoo tuaj yeem txhim kho cov tsos mob rau qee yam.
Kev qhia txog kev noj qab haus huv rau cov neeg mob Parkinson's disease
1. Kev qoj ib ce ntxiv: Kev tshawb fawb thiab kev tawm dag zog yog qhov zoo rau kev tiv thaiv tus kab mob Parkinson. Cov neeg mob Parkinson yuav tsum tau siv zog ntau npaum li lawv tuaj yeem ua tau raws li kev qhia ntawm tus kws kho mob tshwj xeeb. Piv txwv li, hais kom cov neeg mob tsa lawv ob txhais ceg, ua cov kauj ruam loj, thiab ua txoj hauv kev nkhaus yog qhov zoo rau kev ncua kev poob ntawm lub cev muaj zog. Piv txwv li, qee qhov kev tawm dag zog xws li Tai Chi tuaj yeem cob qhia tus neeg mob qhov sib npaug.
2. Kev saib xyuas kev noj haus: Tus kab mob Parkinson yog ib yam kab mob ntawm lub hauv nruab nrab lub paj hlwb, uas tuaj yeem ua rau lub cev tsis muaj zog, thiab cov neeg mob ua rau cem quav. Nws raug pom zoo tias cov neeg mob uas muaj tus kab mob Parkinson noj cov zaub mov muaj fiber ntau thiab cov txiv hmab txiv ntoo uas muaj cov nyhuv laxative xws li txiv tsawb thiab txiv tsawb los ntawm kev noj zaub mov zoo. Tsis tas li ntawd, cov tshuaj levodopa yuav tsum tau noj ntawm lub plab khoob kom ntau li ntau tau, tshwj xeeb tshaj yog kom tsis txhob noj lawv tib lub sijhawm nrog cov zaub mov muaj protein ntau, thiaj li tsis cuam tshuam rau kev ua tau zoo ntawm cov tshuaj.
3. Tsis txhob sib cuag nrog cov tshuaj lom neeg: Cov tshuaj lom neeg muaj xws li tshuaj tua kab, tshuaj tua kab, tshuaj tua kab, thiab lwm yam. Nyob rau tib lub sijhawm, cov hlau hnyav hlau manganese thiab hluav taws xob yuav tsum raug zam. Cov neeg ua haujlwm hauv cheeb tsam no yuav tsum tau saib xyuas lawv cov kev sib cais los ntawm cov xwm txheej txaus ntshai.
4. Kev noj zaub mov tsis tu ncua: lub sij hawm noj mov yuav tsum tsis tu ncua thiab kho, thiab cov khoom noj yuav tsum tsis txhob loj dhau los yog tag nrho. Thib ob, hais txog cov ntsiab lus ntawm kev noj haus, peb yuav tsum noj cov khoom noj uas muaj txiaj ntsig thiab yooj yim zom xws li cov protein tsawg, cov vitamins siab, cov fiber ntau, thiab lwm yam.
5. Kev tshem tawm tsis tu ncua: Txhawm rau kom ua tiav qhov defecation, koj yuav tsum sim ua kom tiav ib hnub ib zaug, tsis pub ntau tshaj 3 hnub, thiab nws tuaj yeem ua tiav thaum sawv ntxov lossis ua ntej yuav mus pw.
6. Tswj lub cev kom raug: Ua tib zoo saib xyuas qhov tseeb zaum thiab sawv cev thiab kho qhov tsis zoo hauv lub neej txhua hnub.
Tsis muaj kev kho rau tus kab mob no, thiab cov kev kho mob uas twb muaj lawm xws li kev kho tshuaj, kev kho lub cev, thiab cov tshuaj suav tshuaj tuaj yeem txhim kho cov tsos mob zoo nyob rau lub sijhawm. Yog li ntawd, kev txhim kho thiab nthuav kev paub txog tus kab mob no tuaj yeem ua rau cov neeg mob tau kuaj pom ntxov, kho ntxov, thiab tau txais txiaj ntsig ntxov.
EchinacosidehauvCistanchetuaj yeem txhim kho tus cwj pwm tsis zoo ntawm MPTP-induced PD qauv nas, nce striatal dopamine (DA) metabolite 3,4-dihydroxypheny lacetic acid (3,4-dihydroxypheny lacetic acid, DOPAC), thiab siab Vanillic acid. (homovanillic acid, HVA) cov ntsiab lus tseem ceeb inhibits apoptosis ntawm cerebellar granule neurons tshwm sim los ntawm kev ua kom cov caspase-3 thiab caspase-8; txo qhov overexpression ntawm biliverdin reductase B nyob rau hauv lub hlwb ntawm Parkinson cov neeg mob, qhia Echinacoside txo qhov nce ntawm biliverdin reductase B los ntawm oxidative kev nyuaj siab los ntawm nws anti-oxidative kev nyuaj siab, thiab tiv thaiv dopaminergic neurons los ntawmoxidativekev puas tsuaj. Nws cov txheej txheem tiv thaiv neuroprotective yuav zoo ib yam li cov kua tsib Cov qib ntawm chlorophyll reductase B muaj feem xyuam; mus rau qhov txo ntawmtshuaj dopaminergicneuronsthiab dopamine transporters nyob rau hauv substantia nigra ntawm lub paj hlwb ntawm cov neeg mob Parkinson tus kab mob, thiab tuaj yeem txhim khoneurotrophicfactor [Neurotrophic factor, NTF. hlwb-derived neurotrophic factor, BDNF) thiab cov hlab ntsha Cov kev ua ub no thiab cov protein qhia theem ntawm glial cell line-derived neurotrophic factor (GDNF) muab tau los ntawm glial cell kab tuaj yeem txo qhov piv ntawm mRNA thiab protein nyob rau hauvapoptosisthiab Bax/Bcl-2. Ntxiv rau,echinacoside cov tshuajtuaj yeem nce cov ntsiab lus ntawm dopamine, DOPAC, thiab HVA nyob rau hauv cov kua dej ntxiv ntawm cov striatum ntawm cov neeg mob.Parkinson tus kab mobkab mob.
Yog xav paub ntxiv: Ali.ma@wecistanche.com
