Ntev-ntev cem quav tuaj yeem cuam tshuam rau kev paub txog kev ua haujlwm?

Kev cem quav, qhov mob tsis txaus ntseeg, ua rau muaj kev nyuaj siab ntau tus phooj ywg. Txawm hais tias tib neeg kev nyuaj siab thiab kev xyiv fab tsis zoo ib yam, thaum cem quav, tej zaum lawv kuj zoo ib yam. Lawv tau sim lawv qhov zoo tshaj plaws, tab sis tseem muaj "tsis muaj qoob loo". Kev xav hauv chav dej mus ib txhis tsis zoo ib yam. Xav zoo.

Nyem rau tam sim ntawd cem quav nyem

Struggling to have a bowel movement once in a while is not considered constipation. Constipation refers to having less than three bowel movements per week, dry and hard stools, and difficulty in defecation. Occasional constipation is common, but when constipation lasts for >12 lub lis piam, nws suav hais tias yog cem quav.

Raws li peb txhua tus paub, kev cem quav ntev ntev ua rau lub cev tsis zoo. Piv txwv li, mob plab thiab tsam plab cuam tshuam rau lub neej zoo thiab tuaj yeem ua rau cov hemorrhoids sib xyaw, qhov quav fissures, thiab qhov quav prolapse. Yog li cov lus nug yog, koj puas paub tias qhov zaus ntawm lub plab zom mov tuaj yeem cuam tshuam rau kev txawj ntse?

Tsis ntev los no, University of Massachusetts, Harvard University, thiab lwm lub tsev kawm ntawv tau koom ua ke luam tawm cov ntaub ntawv tshawb fawb hauv phau ntawv xov xwm Neurology uas muaj npe nrov, hu ua "Association between Bowel-Movement Pattern and Cognitive Function: Prospective Cohort Study and a Metagenomic Analysis of the Gut Microbiome" . Cov txiaj ntsig tau pom tias, piv nrog rau cov neeg uas muaj plab hnyuv ib hnub ib zaug, cov neeg uas muaj lub plab zom mov txhua 3 hnub lossis ntau dua tau muaj kev paub tsis zoo, uas yog sib npaug rau peb xyoos ntawm kev txawj ntse poob. Qhov no tej zaum yuav muaj feem xyuam rau plab hnyuv microbiota thiab cov kab mob tshwj xeeb. Hom muaj feem cuam tshuam.

Nyob rau hauv txoj kev tshawb no yav tom ntej, cov kws tshawb fawb tau tshuaj xyuas qhov kev sib raug zoo ntawm lub plab zom mov ntau zaus thiab lub hom phiaj ntsuas kev paub txog kev ua haujlwm hauv 12,696 tus poj niam kawm los ntawm Tus Saib Xyuas Kev Noj Qab Haus Huv II (NHHSII); Kev sib raug zoo ntawm kev ua haujlwm ntawm lub plab zom mov thiab kev paub txog kev ua haujlwm ntawm 113,145 tus poj niam thiab txiv neej hauv peb pawg ntawm Kev Tshawb Fawb Kev Ua Haujlwm (HPFS). Hauv kev tshuaj ntsuam xyuas, peb tau tshuaj xyuas qhov kev sib cuam tshuam ntawm qhov tso zis ntau zaus, plab microbiota, thiab kev paub txog kev ua haujlwm hauv 515 yam ntawm NHSII thiab HPFS.

Cov kws tshawb fawb tau faib cov pej xeem txoj kev tshawb fawb no ua plaub pawg raws li qhov zaus ntawm lub plab zom mov: txhua peb hnub lossis ntau dua, txhua hnub, txhua hnub, thiab ob lossis ntau zaus hauv ib hnub. Thaum lub sij hawm ntawm qhov kev ntsuam xyuas lub plab zom mov, qhov nruab nrab hnub nyoog ntawm cov neeg kawm yog 75.7 xyoo hauv NHS, 58.6 xyoo hauv NHS II, thiab 74.5 xyoo hauv HPFS.

Cov neeg koom nrog ntau lub plab zom mov tau tshaj tawm tias kev noj zaub mov muaj fiber ntau ntau dua thiab siv laxative tsawg dua. Cov neeg koom nrog uas muaj ntau dua lossis tsawg dua cov kev tso zis ntau zaus tsis muaj lub cev tsis muaj zog thiab feem ntau yuav muaj cov tsos mob ntawm kev nyuaj siab thiab siv cov tshuaj tiv thaiv kev ntxhov siab ntau dua li cov neeg uas muaj ib qho quav hauv ib hnub.

Cov kws tshawb fawb tau siv CogState computer neuropsychological ntsuam xyuas software los ntsuas lub hom phiaj kev paub txog kev ua haujlwm. Txoj kev tshawb no tau pom tias tom qab hloov kho qhov muaj peev xwm ua rau muaj qhov tsis txaus ntseeg, lub plab zom mov zaus cuam tshuam rau lub hom phiaj kev paub txog kev ua haujlwm hauv qhov hloov pauv J-zoo li koob tshuaj teb. Cov koom haum tshuaj zoo sib xws tau pom muaj rau kev kawm thiab kev ua haujlwm nco, nrog rau kev ceev thiab kev xav ntawm psychomotor.

Hais txog lub hom phiaj kev paub txog kev ua haujlwm, piv nrog rau cov neeg uas tau tso quav tso zis txhua hnub, cov neeg uas muaj plab hnyuv txhua 3 hnub los yog ntau dua muaj qhov kev xav tsis zoo sib npaug rau cov laus los ntawm 3.0 xyoo. Tshwj xeeb yog hais txog kev kawm thiab kev nco ua haujlwm, cov neeg uas muaj lub plab zom mov txhua 3 hnub lossis ntau dua kev paub txog kev puas siab puas ntsws sib npaug rau cov laus los ntawm 7.1 xyoo.

Kev paub txog kev poob qis tau raug soj ntsuam nrog cov lus nug yog / tsis muaj, suav nrog 7 cov lus nug los ntawm NHSII thiab NHS thiab 6 cov lus nug los ntawm HPFS, hais txog tus kheej-pom tsis ntev los no thiab kev paub hloov pauv. Cov txiaj ntsig tau pom qhov hloov pauv J-zoo li koob tshuaj- teb kev sib raug zoo ntawm lub plab zom mov ntau zaus thiab kev paub txog kev xav tsis zoo hauv peb pawg neeg ywj pheej.

Nyob rau hauv cov nqe lus ntawm kev txawj ntse muaj nuj nqi, piv nrog rau cov neeg uas muaj ib tug niaj hnub plab hnyuv txav, cov neeg uas muaj tsawg zaus plob tsis so tswj (ib zaug txhua txhua 3 hnub los yog ntau tshaj) thiab cov neeg uas muaj feem ntau plob tsis so tswj (ob los yog ntau tshaj ib hnub twg) muaj feem ntau dua. ntawm kev txo qis kev paub txog kev txawj ntse. yog 73% thiab 37% siab dua, feem, thiab yog 19% thiab 10% feem ntau yuav yws yws ntawm kev paub txog kev poob qis hauv lub sijhawm. Nyob rau tib lub sijhawm, kuj tseem muaj kev sib raug zoo ntawm cov tshuaj tsis sib haum xeeb ntawm lub plab zom mov thiab qhov yuav ua rau muaj kev puas tsuaj mus ntev hauv kev nco, kev ua haujlwm, kev saib xyuas, thiab kev txawj visuospatial.

Tom ntej no, cov kws tshawb fawb kuj tau tshawb nrhiav lub luag haujlwm ntawm plab hnyuv microbes hauv kev sib raug zoo ntawm plab hnyuv ntau zaus thiab kev paub txog kev ua haujlwm hauv 515 yam. Cov kws tshawb fawb tau taw qhia tias txawm hais tias qhov defecation zaus tsis yog tus tsav tsheb tseem ceeb ntawm txoj hnyuv microbial muaj pes tsawg leeg, PERMANOVA tau pom tias muaj kev cuam tshuam tseem ceeb ntawm qhov defecation zaus thiab tag nrho cov kev hloov pauv hauv plab hnyuv microbiome, thiab muaj qhov tsis sib xws tseem ceeb ntawm qhov defecation zaus thiab. PCO1. Tsis tas li ntawd, kev txawj ntse poob qis tau cuam tshuam nrog tag nrho cov kev hloov pauv hauv plab microbiome thiab tau cuam tshuam zoo nrog PCo1.

Thaum kawg, cov kws tshawb fawb tau txheeb xyuas 19 cov kab mob uas muaj feem cuam tshuam nrog kev tso zis ntau zaus thiab 15 cov kab mob uas muaj feem cuam tshuam rau kev txawj ntse; 3 cov kab mob muaj feem cuam tshuam rau ob qho tib si defecation ntau zaus thiab kev paub txog kev ua haujlwm, suav nrog Tumorococcus tumefaciens thiab Clostridium citrate. thiab anaerobes (An250). Cov kab mob dysbiosis ntsig txog Lepidobacteria, xws li Vibrio parvum, Vibrio allostasis, thiab Vibrio atypical, yog cov kab mob gram-negative thiab nruj me ntsis anaerobic kab mob feem ntau pom nyob rau hauv lub qhov ncauj kab noj hniav, plab hnyuv ib ntsuj av, thiab genitourinary system, thiab yog feem ntau txuam nrog rau defecation.

Hauv cov neeg mob uas tsis tshua muaj lub plab zom mov, qhov txo qis ntawm Roseburia spp., suav nrog cov kab mob loj butyrate uas tsim cov kab mob R. inulinivorans thiab R. faecis, tau pom. Nyob rau hauv cov nqe lus ntawm kev txawj ntse muaj nuj nqi, enrichment ntawm opportunistic pathogen Erysipelatoclostridium ramosum thiab anaerobic kab mob Blautia sp. CAG 257 tau cuam tshuam nrog kev ua haujlwm ntawm kev txawj ntse. Kev noj haus fiber ntau processor thiab butyrate tsim Eubacterium eligens muaj ntau dua nyob rau hauv cov kev kawm uas muaj kev txawj ntse zoo dua.

Feem ntau, cov neeg uas cem quav yuav tsum tau saib xyuas ntau dua. Qhov qis dua qhov kev tso quav, qhov ua rau qhov kev paub txog kev ua haujlwm tsis zoo ntsuas lub hom phiaj, thiab qhov kev pheej hmoo siab ntawm kev paub txog kev poob qis. Kev txhawb nqa ntawm cov kab mob pro-inflammatory microbial thiab depletion ntawm butyrate-ua cov kab mob uas cuam tshuam nrog plab hnyuv microbial dysbiosis tuaj yeem piav qhia qee qhov kev sib txuas ntawm cov txheej txheem ntawm lub plab zom mov thiab kev paub txog kev ua haujlwm.

Coincidentally, ib txoj kev tshawb nrhiav hla hauv kuv lub teb chaws [2] pom tias feem ntau ntawm cem quav yog siab dua rau cov neeg laus hauv Suav teb, thiab feem ntau ntawm cem quav hauv cov neeg mob dementia thiab na-MCI (na-MCI) yog siab dua piv nrog kev paub. cov neeg noj qab nyob zoo. siab dua. Lub Tsev Kawm Ntawv Tshuaj ntawm Suav University of Hong Kong kuj tau luam tawm ib tsab xov xwm [3], uas ntseeg hais tias microbiota-gut-brain axis raug suav hais tias ua lub luag haujlwm tseem ceeb hauv Parkinson's disease (PD), thiab PD-zoo li plab hnyuv dysbiosis. tshwm sim nyob rau hauv prodromal theem ntawm PD. , uas muaj lub ntsiab lus zoo ib yam li txoj kev tshawb no.

Los ntawm cov saum toj no, peb paub tias kev cem quav ntev tsis yog qhov tseem ceeb thiab tsis cuam tshuam rau kev noj qab haus huv ntawm lub cev. Txhawm rau kom txaus siab txaus, peb yuav tsum txhim kho peb txoj kev ua neej thiab mob siab rau nws. Cov kws sau ntawv tau taw qhia tias txoj kev tshawb no tseem muaj qee qhov kev txwv, thiab kev tshawb fawb yav tom ntej yuav tsum tau ua kom paub meej txog kev sib koom ua ke ntawm plab hnyuv ntau zaus thiab kev paub txog kev ua haujlwm thiab ntxiv dag zog rau lub luag haujlwm ntawm lub plab microbiota hauv kev paub tsis meej thiab dementia.

Ntuj Herbal Tshuaj Rau Relieving cem quav-Cistanche

Cistanche yog ib tug genus ntawm parasitic nroj tsuag uas belongs rau tsev neeg Orobanchaceae. Cov nroj tsuag no paub txog lawv cov khoom siv tshuaj thiab tau siv hauv Cov Tshuaj Suav Tshuaj (TCM) rau ntau pua xyoo. Cov hom Cistanche feem ntau pom muaj nyob hauv thaj av qhuav thiab suab puam ntawm Tuam Tshoj, Mongolia, thiab lwm qhov chaw ntawm Central Asia. Cistanche nroj tsuag yog tus cwj pwm los ntawm lawv cov nqaij tawv, yellowish stems thiab muaj nuj nqis heev rau lawv cov txiaj ntsig kev noj qab haus huv. Hauv TCM, Cistanche ntseeg tau tias muaj cov khoom siv tonic thiab feem ntau yog siv los kho lub raum, txhim kho qhov tseem ceeb, thiab txhawb kev ua haujlwm ntawm kev sib deev. Nws kuj yog siv los daws cov teeb meem ntsig txog kev laus, qaug zog, thiab kev noj qab haus huv tag nrho. Thaum Cistanche muaj keeb kwm ntev ntawm kev siv tshuaj ib txwm siv, kev tshawb fawb tshawb fawb txog nws txoj kev ua tau zoo thiab kev nyab xeeb yog tsis tu ncua thiab txwv. Txawm li cas los xij, nws paub tias muaj ntau yam bioactive tebchaw xws li phenylethanoid glycosides, iridoids, lignans, thiab polysaccharides, uas tuaj yeem ua rau nws cov teebmeem tshuaj.

Wecistanche covcistanche hmoov, cistanche ntsiav tshuaj, cistanche capsules, thiab lwm yam khoom tsim los sivsuab puamcistancheraws li cov khoom siv raw, txhua yam muaj txiaj ntsig zoo rau kev tshem tawm cem quav. Cov txheej txheem tshwj xeeb yog raws li hauv qab no: Cistanche ntseeg tau tias muaj cov txiaj ntsig zoo rau kev tshem tawm cem quav raws li nws cov kev siv ib txwm siv thiab qee cov tshuaj uas nws muaj. Txawm hais tias kev tshawb fawb tshawb fawb tshwj xeeb ntawm Cistanche qhov cuam tshuam rau cem quav yog txwv, nws tau xav tias muaj ntau lub tswv yim uas yuav ua rau nws muaj peev xwm txo tau cem quav. Laxative nyhuv:Cistanchetau ntev tau siv nyob rau hauv tsoos suav tshuaj raws li ib tug tshuaj rau cem quav. Nws ntseeg tau tias muaj cov nyhuv laxative me me, uas tuaj yeem pab txhawb kev zom zaub mov thiab ua rau cem quav. Cov nyhuv no tuaj yeem raug ntaus nqi rau ntau lub tebchaw nyob hauv Cistanche, xws li phenylethanoid glycosides thiab polysaccharides. Moistening cov hnyuv: Raws li kev siv ib txwm siv, Cistanche suav hais tias muaj cov khoom siv moisturizing, tshwj xeeb yog tsom rau cov hnyuv. Txhawb nqa dej thiab lubrication ntawm cov hnyuv yuav pab tau cov cuab yeej soften thiab yooj yim dua, yog li no relieving cem quav. Anti-inflammatory Effect: cem quav tej zaum yuav txuam nrog o nyob rau hauv lub plab zom mov. Cistanche muaj qee qhov sib txuas, suav nrog phenylethanoid glycosides thiab lignans, uas ntseeg tau tias muaj cov tshuaj tiv thaiv kab mob. Los ntawm kev txo cov kab mob hauv cov hnyuv, nws tuaj yeem pab txhim kho kev zom zaub mov tsis tu ncua thiab txo qhov cem quav.