Nyob rau theem twg ntawm cov kab mob raum, Uremia yog qhov tsis tuaj yeem zam tau?
Apr 19, 2023
"Tus kws kho mob, kuv puas yuav tau uremia?" Yeej, txhua tus neeg mob raum tau nug tus kws kho mob cov lus nug zoo sib xws. Qee lub sij hawm tus kws kho mob teb tias: "Kev txiav txim los ntawm koj tus mob tam sim no, peb tuaj yeem tswj tau nws zoo, thiab nws cia siab tias nws yuav tsis loj hlob mus rau hauv uremia!" Qee lub sij hawm kuv teb tias: "Koj qhov xwm txheej tam sim no hnyav heev. Txawm hais tias uremia tsis tuaj yeem zam tau, peb yuav tsum ua haujlwm ua ke kom ncua kev loj hlob mus rau uremia thiab ncua kev lim ntshav."
Nyem rau cistanche tubulosa capsules rau kab mob raum
Qhov "watershed" ntawm lub raum kab mob yog qhov tseem ceeb!
Tsis yog txhua tus neeg mob uas mob raum yuav ua rau uremia. Yuav txiav txim "deb" thiab "ze" los ntawm uremia li cas? Ntawm lawv, muaj cov ntaub ntawv tseem ceeb tshaj plaws, uas yog: kab mob raum mob ntev (CKD staging). Hauv CKD staging, CKD3b theem yog qhov dej tseem ceeb rau cov kab mob raum.
Ua ntej CKD theem 3b, nws tuaj yeem hais tias txhua yam kev pheej hmoo raug tswj tau zoo, thiab muaj kev cia siab tias uremia yuav tsis tsim. Tab sis thaum nws los txog rau CKD3b, uremia yog qhov nyuaj rau zam, tshwj xeeb tshaj yog thaum tus neeg mob tseem hluas thaum nws mus txog CKD3b. Thaum cov neeg mob raum paub txog lawv theem CKD, lawv yuav paub tias lawv nyob deb npaum li cas los ntawm uremia.
CKD ua li cas?
CKD staging feem ntau yog nyob ntawm qhov kwv yees glomerular filtration rate (eGFR) ntawm tus neeg mob ntawm lub xeev khov kho.
CKD theem 1 yog eGFR ntau dua 90ml / min; CKD theem 2 yog eGFR ntawm 60-90ml/min.
CKD theem 3 yog thaum eGFR nyob nruab nrab ntawm 30 thiab 60ml / min. Nrog 45ml / min raws li ciam teb, CKD theem 3 tau muab faib ua CKD3a theem thiab CKD3b theem. eGFR ntawm 45 ~ 60ml / min yog CKD3a theem; eGFR ntawm 30 ~ 45ml / min yog CKD3b theem.
CKD theem 4 yog nruab nrab ntawm eGFR15 ~ 30ml / min; CKD theem 5 yog eGFR tsawg dua 15ml / min, thiab CKD theem 5 yog qhov kawg ntawm lub raum tsis ua haujlwm, uas yog, uremia.
Nws yuav tsum tau muab sau tseg tias thaum xam eGFR, cov serum creatinine tus nqi suav nrog yuav tsum tau khaws cia rau hauv lub xeev ruaj khov ntawm lub raum rau yam tsawg kawg 3 lub hlis.
Yog tias nws yog qhov mob raum mob raum, cov ntshav creatinine hloov pauv sai thiab ua nruj ua tsiv nyob rau lub sijhawm luv luv, xws li kev kis kab mob, cov kab mob hauv lub raum, thiab siv cov tshuaj nephrotoxic, thiab qhov xwm txheej no hloov zuj zus. eGFR xam los ntawm cov xwm txheej tsis ruaj khov no tsis suav nrog hauv theem no.
Tsis tas li ntawd, yog tias nws yog tus neeg tsis muaj kab mob raum, qhov ntsuas glomerular filtration rate (GFR) ntau dua 60ml / min, uas yog ib txwm muaj thiab tsis suav nrog CKD theem 1 thiab theem 2.
CKD theem 1 thiab theem 2 tseem nyob deb ntawm uremia, thaum CKD theem 3b thiab CKD theem 4 tseem nyob ze.
Lub ntsiab lus ntawm "watershed" yog dab tsi?
Vim li cas CKD theem 3 muab faib ua theem 3a thiab theem 3b hauv tshuaj? Qhov no yog vim hais tias, thaum mus txog theem CKD3b, qhov kev loj hlob ntawm cov kab mob hauv lub raum yuav nrawm dua, thiab qhov kev poob qis txhua xyoo ntawm eGFR yuav nce sai.
Piv txwv li, hauv qhov kev tshawb nrhiav mus sij hawm ntev no ntawm ntau dua 100, 000 cov neeg, ua ntej cov hauv paus ntsiab lus eGFR ntau dua 45ml / min, qhov nruab nrab eGFR ib xyoos ib zaug poob li ntawm 0-1ml / min ; ib zaug nws poob qis dua 45ml / min, qhov nruab nrab txhua xyoo eGFR poob li ntawm 3ml / min.
Nco tseg: Qhov no tsuas yog cov ntaub ntawv nruab nrab ntawm ib pawg neeg coob hauv txoj kev tshawb fawb. Tshwj xeeb, qhov kev poob qis hauv eGFR txawv ntawm ib tus neeg mus rau ib tus neeg vim muaj cov kab mob sib txawv.
Yuav ua li cas to taub qhov txawv? Yog tias ib tus neeg eGFR yog 45ml / min, thiab qhov nruab nrab txhua xyoo eGFR poob li ntawm 3ml / min, nws siv sijhawm ntev npaum li cas los tsim uremia?
Cov lus teb yog hais txog 10 xyoo.
Nyob rau hauv cov ntaub ntawv ntawm lub raum tsis ua hauj lwm cia, thiab lub xyoo cia tseem poob qis, qhov no yog vim li cas nws thiaj li hais tias CKD theem 3b yog ze rau uremia.
Qhov no yuav luag tag nrho cov hom CKD.
Noj hom kab mob nephritis feem ntau hauv cov tub ntxhais hluas, uas yog IgA nephropathy, kev tshawb fawb tseem hais ntxiv tias qhov kev pheej hmoo ntawm kev kis kab mob yuav ntau dua hauv CKD3b theem.
Yog li, nws puas txhais tau tias cov neeg mob CKD theem 1 thiab theem 2 tuaj yeem so yooj yim vim lawv nyob deb ntawm uremia? Cov neeg mob uas muaj CKD theem 3b thiab 4 yuav tsum tsis txhob tswj hwm. Txawm li cas los xij, txawm tias lawv tswj tau li cas, lawv yuav tsim uremia.
dab tsi yog lub mechanism ntawm Cisanche kho mob raum?
Cistanche yog tshuaj ntsuab siv hauv cov tshuaj suav tshuaj rau kev kho mob raum. Nws cov txheej txheem ntawm kev txiav txim yog xav kom koom nrog nws lub peev xwm los txhim kho cov ntshav khiav thiab cov khoom noj khoom haus xa mus rau ob lub raum, nrog rau nws cov tshuaj tiv thaiv kab mob thiab antioxidant.
Ib txoj kev tshawb fawb luam tawm nyob rau hauv Phau Ntawv Xov Xwm ntawm Ethnopharmacology tau tshaj tawm tias Cistanche extracts txhim kho lub raum ua haujlwm hauv cov nas uas muaj kab mob raum los ntawm kev txo qis kev mob thiab oxidative kev nyuaj siab hauv lub raum. Lwm txoj kev tshawb fawb luam tawm nyob rau hauv European Journal of Pharmacology pom tias Cistanche extracts tswj cov kev ua ntawm qee cov proteins koom nrog rau lub raum ua haujlwm, uas ua rau nws tiv thaiv kev raug mob rau lub raum.
Cov ntaub ntawv:
1. Yang X, Zhang Y, Chen J, Chen J, Chen N. Cov nyhuv tiv thaiv ntawm cistanche flavones ntawm lub raum puas hauv cov nas muaj ntshav siab. Phau ntawv Journal of Ethnopharmacology. 2010; 131(1):221-225. doi: 10.1016/j.jep.2010.06.012
2. Liu W, Liu S, Huang R, Zheng M, Chen R, Tao T. Cistanche deserticola polysaccharide inhibits lub raum apoptosis ntawm PPAR- txoj hauv kev hauv ntshav qab zib nephropathy. European Journal of Pharmacology. 2018;825:{4}}. doi: 10.1016/j.ejphar.2018.02.015.
