Cov koom haum ntawm kev coj cwj pwm tsis zoo thiab lub cev ua si nrog cov teeb meem kev puas siab puas ntsws thiab qib Testosterone Ntawm Cov Tub Ntxhais Kawm Qib Siab hauv Chongqing, Tuam Tshoj Ⅱ
Aug 29, 2024
2 Kev tshwm sim
2.1 Cov yam ntxwv tseem ceeb
Qhov xwm txheej ntawmkev nyuaj siab, kev ntxhov siab,thiabkev nyuaj siabs nyob rau hauv 582 txiv neej cov tub ntxhais kawm ntawv qib siab hauv Chongqing yog 6.70%, 12.71%, thiab 6.70% feem, thiab feem ntau ntawm zaum tsawg dua 6 teev, 6-10 teev, thiab ntau tshaj 10 teev ib hnub yog 31.96%, 57.04 %, thiab 11.00% feem, saib Table 1.
2.2 Kev soj ntsuam ntawm kev koom tes ntawm kev zaum ntev thiab kev tawm dag zog lub cev thiab kev nyuaj siab, kev ntxhov siab, thiab kev ntxhov siab hauv cov tub ntxhais kawm ntawv qib siab
Covtxaus ntshai cov tsos mob ntawm kev nyuaj siab in the group of college students with long-term sitting time>10 h yog 6.66 npaug ntawm pawg tswj hwm (lub sijhawm zaum ntev<6 h group) (OR=6.66, 95% CI: 2.16-20.49, P=0.001); the incidence of depression symptoms in the Q4 group of college students was 0.34 times that of the Q1 group (OR=0.34, 95% CI: 0.13-0.87, P=0.025); there was no statistically significant difference in the association between long-term sitting and physical exercise and anxiety and stress symptoms in college students (all P>0.05). Saib Table 2.
NEW HERBAL FORMULATION RAUKev nyuaj siab, Kev ntxhov siab,THIABTXOJ CAI TSHIABS
NYEM QHOV CHAW UA HAUJ LWM
2.3 Kev soj ntsuam ntawm kev koom tes ntawm kev zaum ntev thiab kev tawm dag zog lub cev thiab testosterone, qib cortisol, thiab testosterone / cortisol piv ntawm cov tub ntxhais kawm ntawv qib siab
Coj cov tub ntxhais kawm ntawv qib siab nrog lub sijhawm zaum ntev<6 as the control group, the serum testosterone level and testosterone/cortisol ratio of college students with long-term sitting time >10 h txo los ntawm 13.22% (95% CI: -19.56% ~ -6.37%, P<0.001) and 11.47% (95% CI: -19.53% ~ -2.60%, P = 0.013), respectively; taking the sports Q1 group as the control group, the serum testosterone level and testosterone/cortisol ratio of college students in the Q4 group increased by 8.02% (95% CI:
1.37% ~ 15. １０％, Ｐ＝０．０１７) 和１１％(９５％CI:{{ 9}}．２４％-２０．８８％, Ｐ＝０００６); Tsis muaj qhov sib txawv tseem ceeb hauv kev koom tes ntawm kev tawm dag zog lub cev thiab qib cortisol (tag nrho P＞００５). Saib Table 3.
2.4 Kev txheeb xyuas kev sib raug zoo ntawm kev zaum ntev thiab kev nyuaj siab, kev ntxhov siab, cov tsos mob ntawm kev ntxhov siab thiab testosterone, qib cortisol, thiab testosterone / cortisol piv rau cov tub ntxhais kawm ntawv qib siab nrog qib kev tawm dag zog lub cev
Ntawm cov tub ntxhais kawm ntawv qib siab nrog qib kev tawm dag zog lub cev, nrog lub sijhawm zaum ntev ntawm<6 has the reference group, there was no significant difference in the association between long-term sitting of >6 h thiab kev nyuaj siab, ntxhov siab vim, kev ntxhov siab, thiab testosterone, cortisol, thiab testosterone / cortisol piv (tag nrho P＞００５). Saib Table 4.
| Hloov pauv | Qhov tseem ceeb feature | Hloov pauv | Qhov tseem ceeb feature |
|---|---|---|---|
| Hnub nyoog/xyoo | 22.00 (22.00, 23.00) | Sedentary cwj pwm / h | |
| Qhov siab / cm | 173.00 (169.00, 176.00) | <6 | 186 (31.96) |
| Qhov hnyav / kg | 65.00 (59.55, 72.20) | 6-10 | 332 (57.04) |
| BMI / (kg m²) | 21.76 (20.21, 23.73) | >10 | 64 (11.00) |
| Kev haus luam yeeb | 131 (22.51) | PARS -3 qhab-nees/score | 24.00 (8.00, 48.00) |
| Haus | 435 (74.74) | Cov tsos mob ntxhov siab | 74 (12.71) |
| Testosterone / (ng·m⁻¹) | 3.64 (2.99, 4.36) | Cov tsos mob ntawm kev nyuaj siab | 39 (6.70) |
| Cortisol / (μmol·L⁻¹) | 204.74 (179.31, 239.32) | Cov tsos mob ntxhov siab | 39 (6.70) |
Nco tseg:
- PARS-3 yog hais txog qhov ntsuas qhov ntsuas ntawm lub cev -3.
- Cov txiaj ntsig hauv kab lus yog qhov sib txawv ntawm qhov sib txawv.
Table 2: Kev Koom Tes ntawm Kev Coj Tus Cwj Pwm thiab Lub Cev Ua Si Nrog Kev Nyuaj Siab, Kev ntxhov siab, thiab kev ntxhov siab hauv cov tub ntxhais kawm ntawv qib siab
| Hloov pauv | LOSSIS Tus nqi | P Tus nqi | (95% CI) | LOSSIS Tus nqi | P Tus nqi | (95% CI) | LOSSIS Tus nqi | P Tus nqi | (95% CI) | |
| Sedentary cwj pwm / h | ||||||||||
| <6 | 1.00 | 1.00 | ||||||||
| 6-10 | 2.61 (0.99–7.07) | 0.059 | 1.69 (0.92–3.08) | |||||||
| >10 | 6.66 (2.16–20.49) | 0.094 | 2.31 (0.90–5.92) | |||||||
| Lub cev ua haujlwm | ||||||||||
| Q1 | 1.00 | 1.00 | ||||||||
| Q2 | 0.37 (0.14–1.00) | 0.050 | 0.98 (0.49–1.96) | 0.949 | 0.74 (0.26–1.86) | 0.560 | ||||
| Q3 | 0.68 (0.30–1.56) | 0.197 | 0.62 (0.30–1.31) | 0.850 | 0.42 (0.14–1.22) | 0.107 |
Nco tseg:
- Logistic regression tsom xam tau siv, kho lub hnub nyoog, BMI, haus luam yeeb, thiab haus.
Lub cev ua si tau muab faib ua quartiles raws li cov qhab nia ntawm qhov ntsuas lub cev ua si -3.
Table 3: Kev Koom Tes ntawm Kev Coj Tus Cwj Pwm thiab Lub Cev Ua Si nrog Testosterone thiab Cortisol Qib, thiab Testosterone / Cortisol Ratio hauv Cov Tub Ntxhais Kawm Qib Siab
3 Kev sib tham
Kev txhawb nqa cov tub ntxhais kawm kev noj qab haus huv ntawm lub cev thiab lub hlwb thiab kev loj hlob thoob plaws txhua qhov yog qhov teeb meem loj ntawm kev txhawj xeeb hauv zej zog. Txoj kev tshawb no pom tau tias zaum ntev yog ib qho kev pheej hmoo raucov menyuam kawm ntawv qib siab kev nyuaj siabthiabtestosterone qib txo, thaum lub cev qoj ib ce yog ib qho kev tiv thaiv rau kev nyuaj siab thiab muaj feem xyuam nrognce qib testosterone. Kev tawm dag zog lub cev siab tuaj yeem cuam tshuam qhov tsis zoo ntawm kev zaum ntev ntawm lub cev.
Daim ntawv tshaj tawm "China National Mental Health Development Report" tau taw qhia tias 21.48% thiab 45.28% ntawm Suav cov tub ntxhais kawm ntawv qib siab muaj kev pheej hmoo ntawm kev nyuaj siab thiab kev ntxhov siab [10]. Wang Hao et al. [11] tau tshawb fawb 3,461 cov tub ntxhais kawm ntawv qib siab thiab pom tias qhov tshwm sim ntawm kev nyuaj siab, kev ntxhov siab, thiab cov tsos mob ntawm kev ntxhov siab yog 11.04%, 10.49%, thiab 4.90% raws li. Txoj kev tshawb no tau pom tias qhov tshwm sim ntawm kev nyuaj siab, ntxhov siab, thiab kev ntxhov siab ntawm cov txiv neej kawm ntawv qib siab hauv Chongqing yog 6.70%, 12.71%, thiab 6.70% feem. Cov ntaub ntawv saum toj no qhia tias kev mob hlwb ntawm cov tub ntxhais kawm hauv tsev kawm qib siab hauv Suav tsis zoo.
Kev zaum ntev yog txuam nrog ntau yam kab mob, nrog rau cov qog nqaij hlav, mob plawv, mob stroke, thiab teeb meem kev puas hlwb. Cov kev tshawb fawb tau pom tias cov neeg uas zaum ntev yog 1.52 npaug ntau dua yuav muaj kev nyuaj siab thiab 3.11 npaug ntau dua yuav muaj cov tsos mob ntawm kev ntxhov siab, feem, piv nrog cov neeg zaum ntev [12].
Kev tawm dag zog lub cev tuaj yeem txo qhov tshwm sim ntawm cov kab mob tsis sib xws xws li kab mob plawv, ntshav siab, thiab ntshav qab zib, thiab txhim kho cov teeb meem kev puas siab puas ntsws [13-14]. Cov kev tshawb fawb tau pom tias cov theem tsim nyog ntawm kev tawm dag zog lub cev muaj feem cuam tshuam nrog txo cov tsos mob ntawm kev nyuaj siab, kev ntxhov siab, thiab kev ua tsis tau zoo [13-14]. Cov kev tshawb fawb tau pom tias 20 mus rau 40 feeb ntawm kev tawm dag zog lub cev ib hnub tuaj yeem cuam tshuam feem ntau ntawm kev pheej hmoo ntawm kev zaum ntev [15]. Cov kev tshawb fawb saum toj no qhia tias kev zaum ntev thiab tsis muaj kev tawm dag zog lub cev yog cuam tshuam nrog kev puas tsuaj rau lub cev thiab lub hlwb. Ib qib siab ntawm kev tawm dag zog lub cev tuaj yeem cuam tshuam qhov tsis zoo ntawm kev zaum ntev ntawm lub cev. Txo lub sijhawm ntawm lub sijhawm sedentary thiab koom nrog kev tawm dag zog lub cev yog qhov tseem ceeb rautxhawb kev noj qab haus huv ntawm lub cev thiab lub hlwb ntawm cov tub ntxhais kawm ntawv qib siab.
Testosterone / cortisol piv yog ib qho rhiab qhia txog qhov sib npaug ntawm tib neeg synthesis thiab catabolism. Kev nce hauv qhov piv tau qhia txog kev txhim kho hauv kev tawm dag zog [16]. Txoj kev tshawb no pom tias zaum ntev tau cuam tshuam nrog kev txo qis hauv cov ntshav cov ntshav testosterone thiab testosterone / cortisol piv, thaum lub cev qoj ib ce muaj feem cuam tshuam nrog kev nce qib hauv cov ntshav testosterone thiab testosterone / cortisol piv. Zoo ib yam li cov txiaj ntsig ntawm txoj kev tshawb fawb no, qee qhov kev tshawb fawb tau pom tias kev cob qhia kev tawm dag zog tuaj yeem nce qib testosterone hauv cov txiv neej thiab poj niam [8]. Txij li qhov sib piv ntawm testosterone / cortisol yog qhov taw qhia rhiab ntawm kev tawm dag zog, feem ntau ntawm cov neeg tuaj yeem pab dawb hauv cov kev tshawb fawb uas twb muaj lawm yog cov neeg ncaws pob, thiab muaj ob peb cov lus ceeb toom ntawm cov pej xeem. Txoj kev tshawb no tau txheeb xyuas qhov sib koom ntawm kev zaum ntev thiab kev tawm dag zog lub cev thiab qhov sib piv ntawm testosterone / cortisol nyob rau hauv cov pej xeem ntawm cov txiv neej kawm ntawv qib siab. Cov kev tshawb fawb xaus muaj qee qhov kev siv tus nqi rau kev txhim kho lub cev ua haujlwm ntawm cov tub ntxhais kawm ntawv qib siab.
Txoj kev tshawb no muaj qee yam kev txwv. Ua ntej, txoj kev tshawb no tsuas yog tsom rau cov txiv neej cov tub ntxhais kawm ntawv qib siab hauv lawv lub xyoo plaub ntawm kev kawm qib siab. Muaj qhov tsis paub tseeb hauv kev nthuav tawm cov kev tshawb fawb xaus rau cov poj niam lossis lwm pab pawg hnub nyoog thiab pab pawg neeg ua haujlwm tshwj xeeb. Qhov thib ob, qhov kev tshawb fawb no yog kev tshawb fawb hla ntu, thiab kev ua qauv qhia ntawm causality yuav tsum muaj kev tshawb fawb sib koom ua ke thiab cov ntaub ntawv hauv vitro xeem nrog cov pov thawj siab dua. Hauv cov ntsiab lus, txoj kev tshawb fawb no pom tias zaum ntev yog qhov muaj feem cuam tshuam rau cov tsos mob ntawm kev nyuaj siab thiab txo qis testosterone qib hauv cov tub ntxhais kawm ntawv qib siab, kev tawm dag zog lub cev yog ib qho kev tiv thaiv rau qhov tshwm sim ntawm cov tsos mob kev nyuaj siab thiab muaj feem xyuam rau kev nce qib testosterone, thiab qib siab. kev tawm dag zog lub cev tuaj yeem cuam tshuam qhov tsis zoo ntawm kev zaum ntev ntawm lub cev.
Cov ntaub ntawv
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