Kev Koom Tes Ntawm Cov Txheej Txheem Pw Tsaug Zog Thiab Nocturia

Cov kev tshawb fawb yav dhau los tau tshaj tawm txog kev sib txuas bidirectional ntawm nocturia thiab pw tsaug zog. Ib txoj kev tshawb fawb luam tawm nyob rau hauv phau ntawv Journal Continence nyob rau hauv lub npe ntawm International Continence Society (ICS) tshawb nrhiav kev sib txuas ntawm kev pw tsaug zog ntsig txog yam thiab nocturia thiab tau muab tso ua ke hauv qab no rau cov txiaj ntsig ntawm cov neeg nyeem.

Nyem rau Cistanche rau mob raum

Kev tshawb fawb keeb kwm

Nocturia is defined as waking up to urinate ≥2 times during sleep. Nocturia occurs in more than 15% of men and women aged 20-40 years, and in older people, the prevalence is >50 xyoo. nce mus rau ntau tshaj 50%. Nws yog txuam nrog comorbidities xws li ntshav qab zib, kab mob plawv, thiab pw tsaug zog. Ntawm cov kab mob no, kev pw tsaug zog tsis zoo, tshwj xeeb tshaj yog obstructive pw tsaug zog apnea, feem ntau cuam tshuam nrog nocturia. Muaj kev sib txuas ntawm ob txoj kev sib txuas ntawm nocturia thiab kev pw tsaug zog tsis zoo, thiab kev pw tsaug zog ntsig txog, xws li snoring lossis pw tsaug zog ntev, tej zaum yuav yog qhov ua rau lossis qhov tshwm sim ntawm nocturia. Txoj kev tshawb no tsom los tshawb txog kev sib koom ua ke ntawm kev pw tsaug zog ntsig txog thiab nocturia thaum tsis muaj kev pw tsaug zog.

Kev tshawb fawb tsim

Pab pawg tshawb fawb tau siv cov ntaub ntawv los ntawm cov neeg teb uas ua tiav Cov Lus Nug Txog Kab Mob Raum thiab Pw Tsaug Zog los ntawm 2005-2018 National Health and Nutrition Examination Survey (NHANES) database. Cov neeg teb xov tooj uas tau tshaj tawm tus kws kho mob-poj niam pw tsis tsaug zog tsis teb cov lus nug txog kev pw tsaug zog lossis muaj lwm yam mob cuam tshuam rau nocturia raug cais tawm. Kev txheeb xyuas ntawm qhov tshwm sim ntawm nocturia los ntawm cov xwm txheej pw tsaug zog (lub sijhawm pw tsaug zog, sijhawm ua haujlwm, snoring zaus, snoring lossis apnea zaus, tsaug zog, thiab tsaug zog) tau ua los tshawb txog kev koom tes ntawm kev pw tsaug zog nrog nocturia, suav nrog hnub nyoog, poj niam txiv neej. , haiv neeg, thiab hnyav. Index (BMI).

Kev tshawb fawb tshwm sim

Pab pawg tshawb fawb zaum kawg suav nrog 23,895 tus neeg teb los ntawm NHANES database (xws li 11,672 txiv neej thiab 12,223 tus poj niam; lub hnub nyoog nruab nrab yog 45.2 ± 20.1 xyoo). Ntawm cov xwm txheej pw tsaug zog, pw tsaug zog<6 hours (38.4%) or >8 teev (38. lub hli Cov neeg uas muaj 16 txog 30 zaug (44.7%) muaj qhov siab tshaj plaws nocturia. Tsis muaj qhov sib txawv ntawm qhov sib txawv ntawm nocturia lossis cov tsos mob tseem ceeb ntawm nocturia los ntawm cov sijhawm ua haujlwm (kev ua haujlwm sawv ntxov, ua haujlwm yav tsaus ntuj, ua haujlwm sawv ntxov thiab yav tsaus ntuj). Kev txheeb xyuas qhov sib txawv tau pom tias cov zis tso zis nocturnal muaj feem xyuam rau hnub nyoog (OR=1.035, p<0.001), BMI (OR=1.038, p<0.001), sleep <6 h (OR=1.603, p<0.001) or >8 h (OR =1}.673, p<0.001), snoring ≥5 nights a week (OR=1.192, p=0.004), snoring or apnea 3 to 4 nights a week (OR=1.425, p<0.001), and snoring or apnea every week ≥5 nights (OR=1.528, p<0.001), sleepiness and drowsiness 5-15 times/month (OR=1.579, p<0.001) to 16-30 times/month (OR=1.970, p<0.001). In multivariate analysis, only age (OR=1.035, p<0.001), BMI (OR=1.032, p<0.001), and sleepiness and sleepiness (OR=1.169, p<0.001) were associated with nocturia.

Analysis xaus

Txawm hais tias feem ntau cov teeb meem ntsig txog kev pw tsaug zog tau pom tias muaj kev nce ntxiv ntawm nocturia ntawm qhov siab tshaj, tsuas yog somnolence thiab pw tsaug zog tau cuam tshuam nrog nocturia hauv kev tshuaj xyuas ntau yam. Kev ua haujlwm yav tom ntej yog xav tau los tshuaj xyuas ntxiv txog cov teeb meem pw tsaug zog uas cuam tshuam nrog nocturia thiab elucidate causal kev sib raug zoo.

Cistanche kho mob raum li cas?

Cistancheyog ib hom tshuaj suav tshuaj ntsuab siv rau ntau pua xyoo los kho ntau yam mob, suav nrograumkab mob. Nws yog muab los ntawm qhuav stems ntawmCistanchedeserticola, ib tsob nroj nyob rau hauv cov suab puam ntawm Tuam Tshoj thiab Mongolia. Lub ntsiab active Cheebtsam ntawm cistanche yogphenylethanoidglycosides, echinacoside cov tshuaj, thiabacteoside, uas tau pom tias muaj txiaj ntsig zoo rauraumnoj qab haus huv.

Kab mob raum, tseem hu ua kab mob raum, hais txog ib yam mob uas lub raum ua haujlwm tsis zoo. Qhov no tuaj yeem ua rau muaj cov khoom pov tseg thiab cov co toxins hauv lub cev, ua rau muaj ntau yam tsos mob thiab teeb meem. Cistanche tuaj yeem pab kho mob raum ase los ntawm ntau lub tshuab.

Ua ntej, cistanche tau pom tias muaj cov nyhuv diuretic, txhais tau tias nws tuaj yeem ua rau cov zis ntau ntxiv thiab pab tshem tawm cov khoom pov tseg ntawm lub cev. Qhov no tuaj yeem pab txo lub nra ntawm lub raum thiab tiv thaiv kev tsim cov co toxins. Los ntawm kev txhawb nqa diuresis, cistanche kuj tseem tuaj yeem pab txo qis ntshav siab, ib qho teeb meem ntawm cov kab mob raum.

Ntxiv mus, cistanche tau pom tias muaj cov teebmeem antioxidant. Kev ntxhov siab oxidative, tshwm sim los ntawm qhov tsis sib xws ntawm kev tsim cov dawb radicals thiab lub cev tiv thaiv antioxidant, ua lub luag haujlwm tseem ceeb hauv kev mob raum. ies pab neutralize dawb radicals thiab txo Oxidative kev nyuaj siab, yog li tiv thaiv lub raum los ntawm kev puas tsuaj. Cov phenylethanoid glycosides pom hauv cistanche tau tshwj xeeb hauv kev tshem tawm cov dawb radicals thiab inhibiting lipid peroxidation.

Tsis tas li ntawd, cistanche tau pom tias muaj cov nyhuv anti-inflammatory. Kev mob yog lwm yam tseem ceeb hauv kev loj hlob thiab kev loj hlob ntawm cov kab mob raum. Cistanche's anti-inflammatory zog pab txo cov zus tau tej cov pro-inflammatory cytokines thiab inhibit qhov ua kom o yuav tsum tau txoj kev, yog li alleviating o nyob rau hauv lub raum.

Tsis tas li ntawd, cistanche tau pom tias muaj cov teebmeem immunomodulatory. Hauv kab mob raum, lub cev tiv thaiv kab mob tuaj yeem ua rau tsis zoo, ua rau muaj kev mob ntau dhau thiab cov ntaub so ntswg puas. Cistanche pab tswj lub cev tiv thaiv kab mob los ntawm kev hloov kho kev tsim khoom thiab kev ua haujlwm ntawm lub cev tiv thaiv kab mob, xws li T hlwb thiab macrophages. Txoj cai tiv thaiv kab mob no pab txo qhov mob thiab tiv thaiv kev puas tsuaj ntxiv rau lub raum.

Ntxiv mus, cistanche tau pom los txhim kho lub raum kev ua haujlwm los ntawm kev txhawb nqa kev tsim kho ntawm lub raum hlab nrog cov hlwb. Lub raum tubular epithelial hlwb ua lub luag haujlwm tseem ceeb hauv kev pom thiab rov nqus cov khoom pov tseg thiab electrolytes. Hauv kab mob raum, cov hlwb no tuaj yeem raug puas tsuaj, ua rau lub raum ua haujlwm puas. Cistanche lub peev xwm los txhawb kev tsim kho ntawm cov hlwb no pab kho lub raum kom zoo thiab txhim kho lub raum tag nrho.

Ntxiv nrog rau cov kev cuam tshuam ncaj qha rau lub raum, cistanche tau pom tias muaj txiaj ntsig zoo rau lwm yam kabmob thiab lub cev hauv lub cev. Txoj hauv kev zoo rau kev noj qab haus huv no tseem ceeb tshwj xeeb hauv cov kab mob raum, vim tias tus mob feem ntau cuam tshuam rau ntau lub cev thiab lub cev. che tau pom tias muaj kev tiv thaiv rau lub siab, lub plawv, thiab cov hlab ntsha, uas feem ntau cuam tshuam los ntawm kab mob raum. Los ntawm kev txhawb nqa kev noj qab haus huv ntawm cov kabmob no, cistanche pab txhim kho lub raum tag nrho thiab tiv thaiv kev mob ntxiv.

Hauv kev xaus, cistanche yog cov tshuaj suav tshuaj ntsuab siv rau ntau pua xyoo los kho mob raum. Nws cov active Cheebtsam muaj diuretic, antioxidant, anti-inflammatory, immunomodulatory, thiab regenerative teebmeem, uas pab txhim kho lub raum ua haujlwm thiab tiv thaiv ob lub raum los ntawm kev puas tsuaj ntxiv. , cistanche muaj txiaj ntsig zoo rau lwm yam kabmob thiab lub cev, ua rau nws txoj hauv kev zoo rau kev kho mob raum.