Kev Ntsuam Xyuas Qhov Ntsuas Thiab Kev Kho Mob Qhov Sib txawv ntawm Kev Ua Haujlwm Thiab Organic Constipation Me Nyuam Yaus: Kev Tshawb Fawb Txog Kev Tshawb Fawb Hauv Pediatric Gastroenterology ClinicsⅡ
Dec 27, 2023
Cov txiaj ntsig
Thaum lub sijhawm kawm, 7,287 lub sijhawm teem sijhawm tau teem rau hauv cov chaw kho mob plab menyuam yaus sab nraud uas tau saib xyuas los ntawm 4,346 tus neeg mob. Ntawm qhov kawg, 639 tus neeg mob (14.7%) tau mus rau hauv tsev kho mob vim yog cem quav ntev. Nees nkaum-peb tus neeg mob (3.6%) raug cais tawm; 20 ntawm lawv muaj duplicaterecords, 2 tus neeg mob tsis ua tiav cov txheej txheem suav nrog thiab lawv muaj hnub nyoog qis dua 1 lub hlis, thiab 1 tus neeg mob raug tshem tawm vim ploj tag nrho cov ntaub ntawv. Qhov seem 616 tus neeg mob (96.4%) tau suav nrog hauv txoj kev tshawb no.
Raws li 2020 Bahrain kev txheeb cais, ntawm 1,472,204 tag nrho cov pejxeem ntawm Bahrain, 481,819 yog menyuam yaus hnub nyoog qis dua 18 xyoo. Yog li ntawd, tag nrho cov feem ntau ntawm cem quav nyob rau hauv cov me nyuam raug xa mus rau tertiary gastrointestinal chaw kho mob yog 0.13% (127.9 cov neeg mob ib 100,000cov neeg uas muaj kev pheej hmoo).Feem ntau ntawm cov neeg mob muaj FC (n=511, 83% ), thaum lub resthad OC (n{15}}, 17%). Cov ntaub ntawv pej xeem ntawm cov neeg mob suav nrog tau pom nyob rau hauv Table 1. Feem ntau yog Bahraini (n{18}}, 95.5%), thaum lwm tus tsis yog Bahraini (n=28,4.5%) (9 tus neeg mob yog los ntawm tim lyiv teb chaws, 6 los ntawm Pakistan, 5 los ntawm Syria, 2 los ntawm Saudi Arabia, Is Nrias teb, thiab Yemen txhua tus, thiab ib tug yog los ntawm Jordan thiab Philippine txhua). FC tau pom tias muaj ntau dua ntawm cov poj niam thiab Bahrainis.
Txawm li cas los xij, tsis muaj qhov sib txawv tseem ceeb ntawm 2 hom cem quav raws li poj niam txiv neej haiv neeg. Lub hnub nyoog nruab nrab ntawm lub sijhawm kuaj mob yog 5.9 xyoo (IQR, 2.3–9.2 xyoo) thaum lub hnub nyoog nruab nrab ntawm lub sijhawm kawm yog 10 xyoo (IQR, 6–13 xyoo). Lub hnub nyoog tshaj plawspab pawg ntawm kev nthuav qhia yog qis dua 5 xyoos (n=275, 44.6%). Muaj qhov sib txawv tseem ceeb ntawm FC thiab OC raws li pawg hnub nyoog (P<0.001). OC was found to be more in younger children compared to FC with a median age at diagnosis of 3.1 years (IQR, 1.5–7.3 years) versus 6.3 years (IQR, 2.7–9.4 years), respectively, P<0.001.
Tsis muaj qhov sib txawv ntawm BMI ntawm OC thiab FC pawg (P=0.204) lossis lub caij huab cua (P=0.592) thaum pib cem quav. Txawm li cas los xij, cov neeg mob uas muaj OCwere txo qis hauv lub cev hnyav (P<0.001) and more stunted (P<0.001) than those with FC. The analysis of growth parameters is shown in Table 1. There was no significant difference between FC and OC in terms of obesity. However, when we combined patients with a possible risk of overweight, overweight, and obesity and compared them with thinness and normal-weight patients, children with FC were more in the higher weight group (P=0.023).
Cov organic ua rau cem quav yog qhia nyob rau hauv Table 2. Covtag nrho cov organic ua tau nyob rau hauv kev txiav txim ntawm neurological ua, ua xua, endocrine, plab hnyuv, thiab caj ces kab mob.Txawm li cas los xij, CMPA yog qhov tshwj xeeb tshaj plaws (n{0}}, 5.7%), raws li kev mob hlwb (n=27) , 4.4%) thiab hypothyroidism (n=15, 2.4%)). Qee cov neeg mob muaj ntau tshaj ib qho ua rau organic.Ib puas tsib caug-tsib tus neeg mob (25.2%) muaj ib lossis ntau dua cov kab mob uas tsis suav tias yog qhov ua rau cem quav. Cov menyuam yaus uas muaj OC muaj feem pua ntawm cov kab mob sib xws (n=120, 33.3%) dua li cov neeg muaj FC (n{15}},23.5%) uas yog qhov tseem ceeb (P=0.037). Cov kab mob uas muaj feem ntau yog enuresis (n=21, 3.4%), raws li SCD (n{23}}, 3%), thiab GERD (n=18, 2.9%).Lwm yam kab mob muaj nyob rau hauv Cov Lus Qhia Ntxiv 1. Kev sib piv ntawm tus neeg mob keeb kwm thiab kev kuaj lub cev nyob nruab nrab ntawm pawg neeg ua haujlwm thiab OC yog qhia hauv Table 3.
Cov ntaub ntawv keeb kwm ntsig txog muaj nyob rau hauv 589 tus neeg mob (95.6%).Cov tsos mob tshwm sim tshaj plaws hauv ob homcem quav yog dhau ntawm cov quav tawv thiab qhuav; tom qab ntawd rov mob plab hauv FC lossis ntuav hauv OC. Qhov tshwm sim ntawm "cov hnoos qeev nrog cov quav" muaj ntau dua hauv OC (P=0.041).Tab sis, tsis muaj qhov sib txawv tseem ceeb hauv cov tsos mob tshwm sim. Raws li cov qauv kev noj haus, 99 (16%) ntawm 142 tus neeg mob (23%) nrog cov ntaub ntawv muaj tau noj cov khoom noj muaj fiber ntau (89 ntawm 124 tus neeg mob [71.8%) hauv FC pawg piv rau 10 ntawm 18 [55.6%] hauv pawg OC. , P=0.177). Cov ntaub ntawv hais txog kev noj mis nyuj muaj nyob hauv 52 tus neeg mob (8.4%), 14 (26.9%) ntawm lawv muaj keeb kwm ntawm kev noj ntau (11 ntawm 35 tus neeg mob [34.4%) hauv FC pawg piv rau 3 ntawm 17 [17.7%] hauv pawg OC, P=0.341). Cov ntaub ntawv hais txog tsev neeg keeb kwm tau zoo rau cem quav hauv ib tus neeg mob nrog FC tawm ntawm 17 nrog cov ntaub ntawv muaj (5.8%). Kev kuaj lub cev tsis zoo nyob rau hauv feem ntau ntawm cov neeg mob (n=494, 80.2%) thaum pom lub cev zoo hauv 93 tus neeg mob (15.1%), 80 (19.5%) los ntawm FCgroup, thiab 13 (12.4%) los ntawm OC. pab pawg.
Qhov feem ntau pom nyob rau hauv ob pawg yog mob plab (n=56, 9.1%) ua raws li perianal fissure (n=33, 5.4%). Nyob rau hauv cov nqe lus ntawm deformities, qhov quav prolapse (n=5) thiab umbilical hernia (n=1) tau pom tsuas yog hauv cov neeg mob FC thaum hypotonia (n=3), qhov quav stenosis (n{{ 9}}), thiab meningomyelocele caws pliav (n{10}}) tsuas yog pom nyob rau hauv cov neeg uas muaj OC. Ntawm 616 tus neeg mob, 587 (95.3%) tau txais cov tshuaj kho mob cem quav nrog rau cov lus qhia txog kev noj haus. Qee tus neeg mob xav tau ntau tshaj ib lub laxative rau kev kho mob cem quav. Ua ntej tus neeg mob mus ntsib, 136 tus neeg mob (22%) muaj keeb kwm ntawm kev siv tshuaj laxative los ntawm thawj tus kws kho mob los ntawm Lub Tsev Haujlwm Saib Xyuas Xwm Ceev.
Feem ntau siv laxative siv ua ntej mus ntsib yog lactulose (n{0}}, 64%), tom qab los ntawm magnesium hydroxide (n=22, 16.2%), polyethylene glycoln{{{{10}}}}, 10.3%), bisacodyl (n=9, 6.6%), glycerin suppositories (n=2, 1.5%), disodium phosphate thiab tshuaj ntsuab (n=1, 0.7% txhua). Thaum 508 tus neeg mob (82.5%) tau txais kev kho mob tom qab kuaj mob gastroenterology. Ntau hom kev kho mob muab los ntawm cov kws kho mob gastroenterologist rau kev kho mob cem quav yog qhia nyob rau hauv Table 4. Cov tshuaj siv ntau tshaj plaws yog lactulose (n=395, 64.1%), ua raws li magnesiumhydroxide (n=265, 43%). thiab glycerin suppository (n=255, 41.4%). Ob tus neeg mob (0.3%) tau noj tshuaj ntxiv hlau. Tsis muaj qhov sib txawv ntawm hom laxative siv tau pom nyob nruab nrab ntawm FC thiab OC.Cov ntaub ntawv hais txog cov lus teb rau kev kho mob muaj rau 126 tus neeg mob (20.5%), 114 (90.5%) ntawm lawv muaj cov lus teb zoo thaum 12 tus neeg mob (9.5%) muaj cov lus teb tsis zoo.
Tsis muaj qhov txawv txav hauv cov lus teb zoo rau kev siv laxative tau pom nyob nruab nrab ntawm FC thiab OC (104 ntawm 115 tus neeg mob [90.4%] hauv FCgroup vs. 10 ntawm 11 [90.9%] hauv pawg OC, P=1.{{ 9}}). Xya tus neeg mob (5.6%) tau ua raws li cov tshuaj tsis zoo. Tawm ntawm 616 tus neeg mob, 527 (85.6%) xav tau ntau dua 1 qhov kev soj ntsuam xyuas, thaum seem 89 (14.4%) tau tuaj koom lub tsev kho mob ib zaug. Tsis muaj qhov sib txawv ntawm qhov nruab nrab ntawm kev mus ntsib kws kho mob sab nraud ntawm 2 pawg (P{{ 22.310). Cov menyuam yaus uas muaj OC yuav tsum tau ua raws sijhawm ntev dua piv rau cov uas muaj FC, tab sis qhov kev tshawb pom no tsis tseem ceeb (P=0.059) (Table1).
Ntuj Herbal Tshuaj Rau Relieving cem quav-Cistanche
Cistanche yog ib tug genus ntawm parasitic nroj tsuag uas belongs rau tsev neeg Orobanchaceae. Cov nroj tsuag no paub txog lawv cov khoom siv tshuaj thiab tau siv hauv Cov Tshuaj Suav Tshuaj (TCM) rau ntau pua xyoo. Cov hom Cistanche feem ntau pom muaj nyob hauv thaj av qhuav thiab suab puam ntawm Tuam Tshoj, Mongolia, thiab lwm qhov chaw ntawm Central Asia. Cistanche nroj tsuag yog tus cwj pwm los ntawm lawv cov nqaij tawv, yellowish stems thiab muaj nuj nqis heev rau lawv cov txiaj ntsig kev noj qab haus huv. Hauv TCM, Cistanche ntseeg tau tias muaj cov khoom siv tonic thiab feem ntau yog siv los kho lub raum, txhim kho qhov tseem ceeb, thiab txhawb kev ua haujlwm ntawm kev sib deev. Nws kuj yog siv los daws cov teeb meem ntsig txog kev laus, qaug zog, thiab kev noj qab haus huv tag nrho. Thaum Cistanche muaj keeb kwm ntev ntawm kev siv tshuaj ib txwm siv, kev tshawb fawb tshawb fawb txog nws txoj kev ua tau zoo thiab kev nyab xeeb yog tsis tu ncua thiab txwv. Txawm li cas los xij, nws paub tias muaj ntau yam bioactive tebchaw xws li phenylethanoid glycosides, iridoids, lignans, thiab polysaccharides, uas tuaj yeem ua rau nws cov teebmeem tshuaj.
Wecistanche covcistanche hmoov, cistanche ntsiav tshuaj, cistanche capsules,thiab lwm yam khoom tsim los sivsuab puamcistancheraws li cov khoom siv raw, txhua yam muaj txiaj ntsig zoo rau kev tshem tawm cem quav. Cov txheej txheem tshwj xeeb yog raws li hauv qab no: Cistanche ntseeg tau tias muaj cov txiaj ntsig zoo rau kev tshem tawm cem quav raws li nws cov kev siv ib txwm siv thiab qee cov tshuaj uas nws muaj. Txawm hais tias kev tshawb fawb tshawb fawb ntawm Cistanche qhov cuam tshuam rau cem quav yog txwv, nws xav tias muaj ntau lub tswv yim uas tuaj yeem pab txhawb rau nws lub peev xwm los daws cem quav. Laxative nyhuv:Cistanchetau ntev tau siv nyob rau hauv tsoos suav tshuaj raws li ib tug tshuaj rau cem quav. Nws ntseeg tau tias muaj cov nyhuv laxative me me, uas tuaj yeem pab txhawb kev zom zaub mov thiab ua rau cem quav. Cov nyhuv no tuaj yeem raug ntaus nqi rau ntau lub tebchaw nyob hauv Cistanche, xws li phenylethanoid glycosides thiab polysaccharides. Moistening cov hnyuv: Raws li kev siv ib txwm siv, Cistanche suav hais tias muaj cov khoom siv moisturizing, tshwj xeeb yog tsom rau cov hnyuv. Txhawb nqa dej thiab lubrication ntawm cov hnyuv yuav pab tau cov cuab yeej soften thiab yooj yim dua, yog li no relieving cem quav. Anti-inflammatory Effect: cem quav tej zaum yuav txuam nrog o nyob rau hauv lub plab zom mov. Cistanche muaj qee qhov sib txuas, suav nrog phenylethanoid glycosides thiab lignans, uas ntseeg tau tias muaj cov tshuaj tiv thaiv kab mob. Los ntawm kev txo cov kab mob hauv cov hnyuv, nws tuaj yeem pab txhim kho kev zom zaub mov tsis tu ncua thiab txo qhov cem quav.
