Kev tshuaj xyuas cov qauv ntawm cov tshuaj suav tshuaj suav tshuaj Cuscuta Chinensis Lam Raws li Cov Ntaub Ntawv Mining
Mar 07, 2024
Abstract:
Lub Hom Phiaj:Raws li cov cai hauv koom haum thiab kev txheeb xyuas pawg, kev tshawb fawb tau ua hauv CuscutaSuav CE rau kev kho mob tshuaj thiab kev tsim cov qauv tshiab.
Txoj kev:Cov tshuaj suav tshuaj suav tshuaj thiab kev npaj yooj yim uas muaj ng Cuscuta chinensisLam nyob rau xyoo 2020 tsab ntawm Suav Pharmacopoeia thiab tsab thib ob ntawm Cov Qauv Tshiab Hauv Tebchaws yogRetrieved thiab soj ntsuam raws li qhov chaw. SPSS Modeler 18.0, SPSS Statistics 27.0, thiab lwm yam.Cov ntsiab lus tshuaj ntawm Cuscuta Suav Lam nyob rau hauv cov tshuaj, nrog rau cov kab mob tseem ceeb, tshuajNtau zaus, cov khoom tseem ceeb, thiab lwm yam. In⁃depth tsom xam ntawm cov tshuaj ua ke yog co. nducted los ntawm kev xaiv high⁃Ntau zaus ntawm kev siv tshuaj thiab hom kab mob.
Cov txiaj ntsig:Cov txiaj ntsig kev tshawb fawb pom tau tias tsib yam tshuaj siv ntau tshaj plaws yog Cuscuta japonica thiab Lily cium barbarum L., Rehmanniae Radix Prapeparata, Angelicas Sinensis Radix, thiab Dioscoreae Rhizoma. Kev txheeb xyuas kev sib raug zoo ntawm cov tshuaj suav tshuaj suav nrog cov neeg yug yaj lub hnab ntim cov noob thiab lawv cov nyiaj tag nrho ua rau 19 feem ntau siv cov tshuaj.
Xaus:Cov tshuaj amaranth feem ntau yog rau kev ua kom tsis txaus thiab tuaj yeem siv ua ke nrog EPI los kho tus txiv neej anterior vaginal kab mob.Cistanche tubulosa. Lawv tuaj yeem ua ke nrog lichen thiab Rehmannia glutinosa raukho mob raum. Lwm cov kab mob thiab cov ntaub ntawv ntau npaum li cas tau kawm los nthuav dav nws txoj kev kho mob.
Ntsiab lus:Suav mole cricket; cov ntaub ntawv mining; kev cai koom haum; kev txheeb xyuas pawg
Cistanche Astragulas Ginseng Capsules
Cuscuta yog Cuscuta australis R.Br. los yog Cuscuta chine los ntawm cov nroj tsuag Convolvulaceae. Cov noob qhuav thiab paub tab ntawm nsis Lam tau pom thawj zaug hauv "Shen Nong's Materia Medica" thiab yog "qib saum toj kawg nkaus" [1]
. Cov tshuaj suav tshuaj suav hais tias Cuscuta cov noob muaj nyob rau hauv daim siab, lub raum, thiab spleen meridians, thiab lawv lub luag haujlwm tseem ceeb yog txhawb nqa lub siab thiab lub raum, ua kom cov phev ruaj khov thiab txo qis tso zis, tiv thaiv fetuses, thiab txhim kho qhov muag [2]. Nws yog pab tau rau kiv taub hau, tinnitus, fetal to vim lub raum tsis muaj peev xwm, thiab raws plab vim spleen deficiency. Cov nyhuv kho tau zoo. Kev txheeb xyuas txoj cai koom haum yog ib txoj hauv kev siv los txheeb xyuas qhov kev sib raug zoo ntawm ntau qhov sib txawv. Nyob rau hauv kev tsom xam ntawm dosing cov cai ntawm dodder npaj, nws feem ntau tshwm raws li kev sib txuas ntawm ob yam tshuaj [3].
Noob ntawm Cuscuta yog ib hom tshuaj suav tshuaj hauv kev kho mob. Txhawm rau ua kom zoo dua qhov sib txawv ntawm qhov sib txawv, kev kho mob, thiab daim ntawv thov kev sib raug zoo, kom ua tau zoo dua cov txiaj ntsig ntawm Noob ntawm Cuscuta, tsab xov xwm no ua cov ntaub ntawv mining ntawm cov tshuaj suav tshuaj uas muaj noob ntawm Cuscuta thiab tshuaj xyuas lawv cov kab mob tseem ceeb thiab cov tsos mob. Qhov kev tsis tu ncua thiab kev sib raug zoo ntawm cov tshuaj siv feem ntau tau kawm, yog li muab qee yam kev siv thiab cov ntaub ntawv siv rau kev kho mob thiab kev loj hlob ntawm Cuscuta phev.
1 Cov ntaub ntawv thiab cov txheej txheem
1.1 Qhov chaw ntawm cov ntaub ntawv
Cov qauv tshuaj hauv tebchaws tau tshawb nrhiav thiab kev txheeb xyuas cov ntaub ntawv tshawb fawb txog cov tshuaj uas muaj cov noob dodder nyob rau hauv 2nd tsab ntawm "Tshiab National Prescriptions" thiab 2020 tsab ntawm "Suav Pharmacopoeia", thiab tag nrho ntawm 314 tau txais [{{ 3}}]
Raws li daim ntawv tshuaj uas muaj Cuscuta phev, cov tshuaj muaj pes tsawg leeg tau tshawb nrhiav thiab tag nrho ntawm 39 cov tshuaj siv ntau zaus raug tshuaj xyuas.
1. 2 Daim ntawv sau npe
Raws li lub teb chaws tus qauv "Clinical Diagnosis and Treatment Terminology of Traditional Chinese Medicine Part 2: Syndrome"
[6], faib cov tshuaj suav tshuaj sau tseg, npe cov noob qoob loo dodder, cov noob txiv hmab txiv ntoo dodder, cov noob dodder kib, thiab cov noob dodder steamed li dodder noob, thiab faib cov kab mob uas lawv kho, xws li raum dej, raum tsis ua haujlwm, thiab lwm yam. . yog cais raws li nephropathy; Carbuncle, phlegm, cystic carbuncle, thiab lwm yam yog cais raws li txiv neej anterior vaginal kab mob; amenorrhea, menstrual leakage, thaum ntxov menstruation, thiab lwm yam yog cais raws li cov poj niam txoj kev coj khaub ncaws, tawm qhov chaw mos, thiab lwm yam kab mob. Nkag mus rau cov ntawv sau tshuaj uas muaj cov noob dodder rau hauv Excel software los tsim cov ntaub ntawv kaw lus, thiab teeb tsa thiab txheeb xyuas cov tshuaj hauv cov ntaub ntawv.
1.3 Kev ua cov ntaub ntawv ntawm cov tshuaj
Siv Excel software los ua cov txheeb cais ntawm qhov zaus thiab meridian tropism ntawm cov tshuaj. Raws li qhov no, lub Plaub Hlis algorithm hauv SPSS Modeler 18.0 software tau siv los ua qauv, thiab kev sib raug zoo ntawm cov tshuaj tseem ceeb raug tshuaj xyuas. Kev sib koom ua ke tau txheeb xyuas siv SPSS Statistics 27.0 software, thiab cov txiaj ntsig kev tshuaj ntsuam tau tshwm sim hauv dendrogram.
2. 2 Kev txheeb xyuas ntawm qhov xwm thiab tsw ntawm cov tshuaj ntsuab ib leeg-tseem siv tshuaj suav tshuaj
Txoj kev xav ntawm cov khoom siv tshuaj ntawm cov tshuaj suav tshuaj yog ib feem tseem ceeb ntawm cov txheej txheem theoretical ntawm cov tshuaj suav tshuaj. Nws suav nrog plaub qi, tsib flavors, meridians, nce thiab poob, tshuaj lom thiab tsis muaj tshuaj lom, thiab lwm yam. Cov khoom thiab saj yog lub hauv paus tseem ceeb rau kev ua tau zoo ntawm cov tshuaj [7]. Cov txiaj ntsig tau txheeb xyuas tau pom nyob rau hauv Table 2. 3. Raws li qhia hauv Table 4. Cov khoom siv tshuaj muaj txiaj ntsig yog sov, ua raws li lub tiaj thiab txias (saib daim duab 1); cov tshuaj saj yog qab zib, ua raws li iab thiab pungent (saib daim duab 2); lub ntsiab meridians yog lub raum, lub siab, thiab tus po, cov txiaj ntsig yog raws li hauv daim duab 3.
2. 3 Cov kev cai koom haum thiab kev txheeb xyuas pawg
Kev txheeb xyuas kev sib raug zoo yog ib txoj hauv kev mining high-frequency khoom teev. Kev txhawb nqa yog tus naj npawb ntawm qhov tshwm sim tsis tu ncua. Qhov loj dua nws tus nqi, qhov ntau dua nws qhov kev faib ua feem. Kev ntseeg siab yog kev ntseeg siab ntawm txoj cai. Qhov loj dua tus nqi, qhov ze ntawm qhov kev sib txuas ntawm ob. Los ntawm SPSS Modeler18. Teem kev ntseeg siab rau 100%, raws li kev txhim kho qib> 1. Raws li qhov system default siab tshaj plaws ntawm cov kev sib txuas yog 80, cov kev sib txuas tsis muaj zog yog teem rau 5, thiab cov kev sib txuas muaj zog yog teem rau 60. Cov kab tuab, qhov ze dua. kev sib txuas. Tom qab mining tej zaum cov tshuaj sib xyaw ua ke, 19 cov tshuaj ua ke nrog Cuscuta raws li cov tub ntxhais tau txais. Cov txiaj ntsig kev txheeb cais tau pom nyob rau hauv Table 5, thiab cov kev sib raug zoo ntawm cov tshuaj siv tshuaj ntau zaus tau pom hauv daim duab 4.
2. 2 Kev txheeb xyuas ntawm qhov xwm thiab tsw ntawm cov tshuaj ntsuab ib leeg-tseem siv tshuaj suav tshuaj
Txoj kev xav ntawm cov khoom siv tshuaj ntawm cov tshuaj suav tshuaj yog ib feem tseem ceeb ntawm cov txheej txheem theoretical ntawm cov tshuaj suav tshuaj. Nws suav nrog plaub qi, tsib flavors, meridians, nce thiab poob, tshuaj lom thiab tsis muaj tshuaj lom, thiab lwm yam. Cov khoom thiab saj yog lub hauv paus tseem ceeb rau kev ua tau zoo ntawm cov tshuaj [7]. Cov txiaj ntsig tau txheeb xyuas tau pom nyob rau hauv Table 2. 3. Raws li qhia hauv Table 4. Cov khoom siv tshuaj muaj txiaj ntsig yog sov, ua raws li lub tiaj thiab txias (saib daim duab 1); cov tshuaj saj yog qab zib, ua raws li iab thiab pungent (saib daim duab 2); lub ntsiab meridians yog lub raum, lub siab, thiab tus po, cov txiaj ntsig yog raws li hauv daim duab 3.
Cistanche Astragulas Ginseng Capsules
2. 3 Cov kev cai koom haum thiab kev txheeb xyuas pawg
Kev txheeb xyuas kev sib raug zoo yog ib txoj hauv kev mining high-frequency khoom teev. Kev txhawb nqa yog tus naj npawb ntawm qhov tshwm sim tsis tu ncua. Qhov loj dua nws tus nqi, qhov ntau dua nws qhov kev faib ua feem. Kev ntseeg siab yog kev ntseeg siab ntawm txoj cai. Qhov loj dua tus nqi, qhov ze ntawm qhov kev sib txuas ntawm ob. Los ntawm SPSS Modeler18. Teem kev ntseeg siab rau 100%, raws li kev txhim kho qib> 1. Raws li qhov system default siab tshaj plaws ntawm cov kev sib txuas yog 80, cov kev sib txuas tsis muaj zog yog teem rau 5, thiab cov kev sib txuas muaj zog yog teem rau 60. Cov kab tuab, qhov ze dua. kev sib txuas. Tom qab mining tej zaum cov tshuaj sib xyaw ua ke, 19 cov tshuaj ua ke nrog Cuscuta raws li cov tub ntxhais tau txais. Cov txiaj ntsig kev txheeb cais tau pom nyob rau hauv Table 5, thiab cov kev sib raug zoo ntawm cov tshuaj siv tshuaj ntau zaus tau pom hauv daim duab 4.
Raws li lub koom haum txoj cai kawm ntawm cov tshuaj suav tshuaj suav tshuaj sib xyaw ua ke ntawm Cuscuta, 19 cov yeeb tshuaj tseem ceeb tau txais, xws li Cuscuta - Lycium barbarum (yang-tonifying tshuaj - deficiency-tonifying tshuaj), Cuscuta - Salvia miltiorrhiza (yang-tonifying tshuaj - ntshav-tiv thaiv thiab ntshav-stasis-tshem cov tshuaj), Cuscuta - Polygonatum (Yang-tonifying tshuaj - yin-tonifying tshuaj), Cuscuta phev - golden Cherry noob (Yang-tonifying tshuaj -
Cov tshuaj astringent), Cuscuta-Polygala (yang-tonifying tshuaj-soothing tshuaj), Cuscuta-Ophiopogon japonicus (yang-tonifying tshuaj-yin-nourishing tshuaj), Cuscuta-cinnamon (yang-tonifying tshuaj-sov tshuaj), Cuscuta noob-Dipsacus (cov tshuaj tonifying) Cuscuta noob - Ligusticum chuanxiong (Yang tshuaj - activating ntshav ncig thiab tshem tawm cov ntshav stasis), Cuscuta noob - Codonopsis cag (Yang tshuaj - Qi tonic tshuaj), Cuscuta noob - Rehmannia glutinosa (Yang tshuaj - tshav kub clearing tshuaj), Cuscuta noob - Deer antler (Yang-tonifying tshuaj-Yang-tonifying tshuaj), Cuscuta Semen-Polygonum multiflorum (Yang-tonifying tshuaj-deficiency-tonifying tshuaj), Cuscuta Seed-Ginseng (Yang-tonifying tshuaj-Qi-tonifying tshuaj), Cuscuta Seed-Psoralen (Yang-tonifying tshuaj-deficiency-tonifying tshuaj), Cuscuta - Achyranthes bidentata (yang-tonifying tshuaj - ntshav-activate thiab ntshav-stasis-tshem tshuaj), Cuscuta - Eucommia ulmoides (yang-tonifying tshuaj - deficiency- tonifying tshuaj), Cuscuta - Astragalus (Yang-tonifying tshuaj - qi-tonifying tshuaj), Cuscuta - Angelicae (Yang-tonifying tshuaj - ntshav tonic). Txhawm rau ua kom tiav, thaum Cuscutae tau siv tshuaj kho mob hauv cov tshuaj suav tshuaj, nws feem ntau siv nrog cov tshuaj tonic, ua kom ntshav thiab ntshav-stasis-tshem cov tshuaj, thiab qi-tonifying tshuaj.
Los ntawm kev txheeb xyuas pawg, tag nrho ntawm 5 pawg ua ke tau txais los ntawm kev sib txuas nruab nrab ntawm cov pedigree (saib daim duab 5). Cluster 1: Suav yam (ua kom cov poov xab thiab plab, nourishes lub raum thiab astringes essence, moistens lub ntsws thiab relieves hnoos), Poria cocos (ua kom cov poov xab thiab calms lub plawv, diuresis thiab dampness), qhia tias hom tshuaj no muaj. cov teebmeem ntawm ntxiv dag zog rau tus po thiab plab, nourishing lub raum, thiab moistening lub ntsws; pawg 2: Rehmannia glutinosa (nourishing yin, replenishing essence, thiab ntshav),Cistanche tubulosa (tonifying lub raum thiab yang, moisturizing cov hnyuvthiab laxative), qhia tau hais tias hom tshuaj no muaj cov txiaj ntsig ntawm nourishing yin thiab nourishing lub raum, moistening cov hnyuv thiab laxatives; Pawg 3: Angelica sinensis (tonifying lub plab hnyuv thiab laxatives) (laxative, tswj kev coj khaub ncaws thiab txo qhov mob), Atractylodes (lub zog spleen thiab replenishing qi, ziab dampness thiab diuresis), thiab Astragalus (tonifying qi thiab ntxiv dag zog rau saum npoo, astringing sores thiab diuresis). txhawb kev loj hlob ntawm cov leeg), qhia tias hom tshuaj no tuaj yeem kho qhov mob thiab cov leeg loj hlob, spleen deficiency syndrome, thiab qi thiab ntshav tsis txaus. Deficiency thiab lwm yam kab mob; Pawg 4: Achyranthes bidentata (tonifying lub siab thiab ntxiv dag zog rau cov leeg, tshem tawm cov ntshav stasis thiab txhawb kev coj khaub ncaws), Psoralen psoralen (ua kom sov lub raum, txhawb yang, absorbing qi thiab nres qi)
raws plab), qhia tau hais tias hom tshuaj no muaj cov nyhuv tonifying lub raum, ntxiv dag zog rau yang, ntxiv dag zog rau cov leeg thiab pob txha, thiab lwm yam.; Cluster 5: Epimedium (tonifying lub raum thiab ntxiv dag zog rau yang, dispelling cua thiab tshem tawm dampness), ginseng (lub zog ntawm tus po thiab lub ntsws, calming lub plawv thiab txhim kho kev txawj ntse, nourishing ntshav thiab txhawb cov kua ntau lawm), Lycium barbarum (tonifying lub raum thiab replenishing. essence, ncua kev laus) thiab Schisandra chinensis (tonifying lub raum thiab calming lub siab, kho qhov chaw thiab tsis txhob tawm hws) qhia tias hom tshuaj no yog siv los kho cov kab mob xws li daim siab thiab lub raum tsis txaus, mob ntawm lub duav thiab lub hauv caug, spleen thiab raum tsis txaus thiab raws plab.
2. 4 Daim ntawv faib khoom noj
Muaj ntau hom tshuaj uas muaj dodder, feem ntau suav nrog cov tshuaj, tshuaj ntsiav, thiab ntsiav tshuaj. Ntawm lawv, qhov zaus ntawm cov ntsiav tshuaj yog 102, suav txog 34%, qhov zaus ntawm cov tshuaj ntsiav yog 48, suav txog 18%, thiab zaus ntawm cov ntsiav tshuaj yog 43, suav txog 16%. Lwm cov txiaj ntsig tau pom nyob rau hauv Table 6. Cov ntsiav tshuaj yog cov tshuaj suav tshuaj suav tshuaj uas yooj yim rau noj, muaj kev ua tau zoo, thiab nqa tau yooj yim. Kuj tseem muaj ntau cov tshuaj ntsiav thiab ntsiav tshuaj, uas muaj qhov zoo ntawm daim ntawv thov dav, siv tau yooj yim, thiab siv tau ntev ntev [8].
